Survival Analysis of Newly Diagnosed Multiple Myeloma Patients after Frontline Autologous Stem Cell Transplantation in a Real-Life Setting
CONCLUSION: ASCT is a feasible, safe, and potent strategy that provides a prolonged median OS and PFS in NDMM patients. This approach can be implemented in low-income countries.PMID:38511422 | DOI:10.14712/18059694.2024.4 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: David Garrido Virginia Bove Fiorella Villano Elo ísa Riva Source Type: research
Gait Disturbance … of Red Herrings, Oranges, and Lemons - A Case of Missed Vitamin C Deficiency and Lessons Learnt
Acta Medica (Hradec Kralove). 2023;66(3):122-127. doi: 10.14712/18059694.2024.5.ABSTRACTVitamin C deficiency resulting in scurvy, is considered to be a rare nutritional disorder in developed countries, thus leading to underdiagnosis with exposure to unnecessary investigations and delay in appropriate treatment. The wide myriad of clinical signs and symptoms with which vitamin C deficiency can present (including haematological, musculoskeletal and vague constitutional symptoms that overlap with other common medical conditions), also contributes to this diagnostic challenge. Despite scurvy being habitually thought to be pres...
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Nadine Anne De Battista Marie Claire Zammit Sandro Galea Soler Stephen Attard Source Type: research
Oral Candidal Infection Misdiagnosed as a Tumour
Acta Medica (Hradec Kralove). 2023;66(3):128-131. doi: 10.14712/18059694.2024.6.ABSTRACTA case report on a 70-year-old male patient with atypical candidal infection on the palate that was misdiagnosed for a tumour based on clinical examination. The lesion was an accidental finding when the patient was at a registered dentist for a preventive check-up.PMID:38511424 | DOI:10.14712/18059694.2024.6 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Wail Abou Assaf Martin Kapit án Lubo š Tuček Jan Laco Source Type: research
Triple Combination with Direct Acting Antivirals in the Treatment of Hepatitis C Does not Prolong the QT Interval
CONCLUSION: The study demonstrates that a combination therapy of 3 antiviral drugs does not significantly prolong the QTc interval and does not cause severe pathological changes on the ECG. Patients undergoing this treatment are not at risk of developing heart disease as an undesirable side effect.PMID:38511419 | DOI:10.14712/18059694.2024.1 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Jakub Šimka Radek Pudil Monika Fialov á Filip Varhan ík Stanislav Pl íšek Petr Pa řízek Source Type: research
Comparison of Short and Long-Term Results after Injection Laryngoplasty with Radiesse ® Voice and Thyroplasty Type I in Unilateral Vocal Fold Palsy
CONCLUSION: These results demonstrate both short and long-term efficiency of injection laryngoplasty and thyroplasty type I in the improvement of voice quality and glottic closure.PMID:38511420 | DOI:10.14712/18059694.2024.2 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Katar ína Smatanová Andr ás Burián Jakub Dr šata Jana Krti čková Anik ó Kőnig-Péter Jan Mejzl ík Viktor Chrobok Source Type: research
The Role of Frailty Scores to Predict the Outcomes in Non Operative Treatment of Valgus Impacted Neck of Femur Fractures
CONCLUSION: This study demonstrates that CFS, AMTS and NHFS can be used as predictors when considering non-operative treatment for the valgus-impacted neck of femur fracture. Patients who are frail, demented and high risk based on the NHFS have higher success rates with non-operative treatment.PMID:38511421 | DOI:10.14712/18059694.2024.3 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Mohammed Ali Chryssa Neo Aysha Rajeev Sharad Bhatnagar Source Type: research
Survival Analysis of Newly Diagnosed Multiple Myeloma Patients after Frontline Autologous Stem Cell Transplantation in a Real-Life Setting
CONCLUSION: ASCT is a feasible, safe, and potent strategy that provides a prolonged median OS and PFS in NDMM patients. This approach can be implemented in low-income countries.PMID:38511422 | DOI:10.14712/18059694.2024.4 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: David Garrido Virginia Bove Fiorella Villano Elo ísa Riva Source Type: research
Gait Disturbance … of Red Herrings, Oranges, and Lemons - A Case of Missed Vitamin C Deficiency and Lessons Learnt
Acta Medica (Hradec Kralove). 2023;66(3):122-127. doi: 10.14712/18059694.2024.5.ABSTRACTVitamin C deficiency resulting in scurvy, is considered to be a rare nutritional disorder in developed countries, thus leading to underdiagnosis with exposure to unnecessary investigations and delay in appropriate treatment. The wide myriad of clinical signs and symptoms with which vitamin C deficiency can present (including haematological, musculoskeletal and vague constitutional symptoms that overlap with other common medical conditions), also contributes to this diagnostic challenge. Despite scurvy being habitually thought to be pres...
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Nadine Anne De Battista Marie Claire Zammit Sandro Galea Soler Stephen Attard Source Type: research
Oral Candidal Infection Misdiagnosed as a Tumour
Acta Medica (Hradec Kralove). 2023;66(3):128-131. doi: 10.14712/18059694.2024.6.ABSTRACTA case report on a 70-year-old male patient with atypical candidal infection on the palate that was misdiagnosed for a tumour based on clinical examination. The lesion was an accidental finding when the patient was at a registered dentist for a preventive check-up.PMID:38511424 | DOI:10.14712/18059694.2024.6 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - March 21, 2024 Category: General Medicine Authors: Wail Abou Assaf Martin Kapit án Lubo š Tuček Jan Laco Source Type: research
Non-contact Vital Signs Monitoring in Paediatric Anaesthesia - Current Challenges and Future Direction
Acta Medica (Hradec Kralove). 2023;66(2):39-46. doi: 10.14712/18059694.2023.14.ABSTRACTNon-contact vital sign monitoring is an area of increasing interest in the clinical scenario since it offers advantages over traditional monitoring using leads and wires. These advantages include reduction in transmission of infection and more freedom of movement. Yet there is a paucity of studies available in the clinical setting particularly in paediatric anaesthesia. This scoping review aims to investigate why contactless monitoring, specifically with red-green-blue cameras, is not implemented in mainstream practise. The challenges, d...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Nicole Grech Jean Calleja Agius Stephen Sciberras Neil Micallef Kenneth Camilleri Owen Falzon Source Type: research
Immunological Parameters in Patients Suffering from Atopic Dermatitis and Either Treated or Non-Treated with Dupilumab
CONCLUSION: We demonstrated the difference in the count of white blood cells populations in patients suffering from AD compared with healthy control. There were a differences in the expression of immunoregulatory molecules CD23 and CD200 on B cells in AD patients (either with or without dupilumab therapy) in comparison to healthy controls.PMID:37930093 | DOI:10.14712/18059694.2023.15 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Petra Boudkov á Jarmila Čelakovská Eva Čermáková Ctirad Andr ýs Jan Krejsek Source Type: research
Evaluation of Diurnal Changes of Mental Fatigue Using a New Portable Device for Visual Cognitive Evoked Potentials
Acta Medica (Hradec Kralove). 2023;66(2):55-60. doi: 10.14712/18059694.2023.16.ABSTRACTIn the age homogenous group of 13 healthy volunteers, we examined visual evoked potentials (VEP) visually evoked cognitive potentials (event-related potentials - ERP) and choice reaction time (CRT) five times during the day (from 10.00 a.m. up to midnight) to verify whether there are significant changes of the measured parameters of the cortical evoked potentials and CRT which might reflect the level of the mental fatigue. The electrophysiological testing was done with the use of a new portable VEP device named "VEPpeak" enabling to perf...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Huey Shin Chua Katrin Ji-In Miller Niha Akhtar Sayyeda Marten Reda Youssef Ibrahim AttaAlla Eithar Osama Eltayeb Babikir Jan Kreml áček Miroslav Kuba Source Type: research
Associations of Serum Total Homocysteine Levels with Various Demographic, Clinical and Genetic Characteristics in Healthy Greek Adults
CONCLUSIONS: Serum tHcy levels are influenced by the existence of MTHFR C677T gene polymorphism (mainly 677TT genotype), serum folate and Cbl levels. Individuals with hyperhomocysteinemia should be further investigated for the existence of MTHFR C677T gene polymorphism, with the aim to determine the suitable treatment.PMID:37930095 | DOI:10.14712/18059694.2023.17 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Elias E Mazokopakis Maria G Papadomanolaki John A Papadakis Source Type: research
COVID-19 Can Unveil Brugada: A Rare Case
Acta Medica (Hradec Kralove). 2023;66(2):68-71. doi: 10.14712/18059694.2023.18.ABSTRACTBrugada syndrome (BRS) is a channelopathy with three characteristic electrocardiogram patterns and an increased risk of sudden cardiac death (SCD), in the absence of gross structural heart disease. Fever is shown to precipitate ventricular arrhythmias in patients with BRS. Here, we report a rare case of Brugada pattern in a patient with Coronavirus Disease 2019 (COVID-19) without fever. A baseline ECG should be considered for patients with COVID-19, even in the absence of fever. COVID-19 by itself may be a factor that can induce Brugada ...
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Savalan Babapoor Zachary Port Philip C Wiener Roozbeh Tarighati Rasekhi Ali Babapour Farrokhran Sumeet K Mainigi Source Type: research
Sodium-Hyaluronate Cystic-like Lesion in the Anterior Chamber Following Cataract Surgery: A Case Report
Acta Medica (Hradec Kralove). 2023;66(2):72-74. doi: 10.14712/18059694.2023.19.ABSTRACTThis is a case report describing the uncommon finding of a cystic-like lesion and its management in the anterior chamber of a male patient after cataract surgery.PMID:37930097 | DOI:10.14712/18059694.2023.19 (Source: Acta Medica: Hradec Kralove)
Source: Acta Medica: Hradec Kralove - November 6, 2023 Category: General Medicine Authors: Christina Mitsi Minas Bakirtzis Eirini-Kanella Panagiotopoulou Georgios Labiris Source Type: research
