The Vitamin-Like Deficiency Linked To Alzheimer ’ s Disease
Inadequate daily intake of this vitamin-like compound can lead to an enlarged heart, liver damage, weight gain as well as Alzheimer’s disease. (Source: PsyBlog | Psychology Blog)
Source: PsyBlog | Psychology Blog - November 4, 2023 Category: Psychiatry & Psychology Authors: Mina Dean Tags: Dementia Source Type: blogs
The critical link between America ’ s obesity epidemic and the liver
Obesity has undeniably become the top health issue of our time, with its prevalence and impact on our bodies making headlines across health care and popular media. This isn’t merely a matter of carrying extra pounds; it’s about the multitude of serious health complications that come in its wake. The conversation around obesity often gravitates
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The critical link between America’s obesity epidemic and the liver originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - November 3, 2023 Category: General Medicine Authors: Darryn Potosky, MD Tags: Conditions Gastroenterology Source Type: blogs
Deathcap mushrooms – Amanita phalloides
What makes the death cap fungus (toadstool or mushroom), Amanita phalloides, so poisonous?
Well, the primary toxin present in this fungus is alpha-amanitin. This chemical goes by the following systematic name, although you’re unlikely to see it spelled out in full in the news about the ongoing murder trial that’s in the Australian news at the moment:
2-[(1R,4S,8R,10S,13S,16S,34S)-34-[(2S)-2-Butanyl]-13-[(2R,3R)-3,4-dihydroxy-2-butanyl]-8,22-dihydroxy-27-oxido-2,5,11,14,30,33,36,39-octaoxo-27-thia-3,6,12,15,25,29,32,35,38-nonaazapentacyclo[14.12.11 .06,10.018,26.019,24]nonatriaconta-18(26),19,21,23-tetraen-4-yl]...
Source: David Bradley Sciencebase - Songs, Snaps, Science - November 2, 2023 Category: Science Authors: David Bradley Tags: Chemistry Health and Medicine Source Type: blogs
Bonus Features – October 29, 2023 – 66% of patients prefer email or text for reminders about medical bills, 94% of clinicians said lack of timely access to insights within EHR impacts patient care, and 28 more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News
CMMI released the 2022 performance results for the direct contracting value-based care model, which has since been redesigned and renamed the ACO REACH Model. All told, participating entities achieved net savings of more t...
Source: EMR and HIPAA - October 29, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT 1upHealth ACO REACH AGS Health Avenda Health Bluefin California HHS Carestream Dental CB Insights Cedar Gate Technologies CMMI CORE eClinicalWorks Fivetran Found Freshpaint FutureRx GSR Ventures Healthcare Source Type: blogs
Fight Aging! Newsletter, October 30th 2023
In conclusion, reported adherence to a healthy lifestyle is associated with reduced risk of all-cause and cause-specific mortality. Adherence to all four lifestyle factors resulted in the strongest protection.
« Back to Top (Source: Fight Aging!)
Source: Fight Aging! - October 29, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Microfluidic System Incorporates Eight Organ Tissues for Drug Testing
Researchers at Northwestern University have developed a sophisticated microfluidic system that incorporates tissue from up to eight different organ systems. The technology is unprecedented in allowing researchers to study complex interactions between different organs during disease. Moreover, it also allows for more comprehensive drug testing that investigates the effects of drug candidates on multiple organ systems at once. Called Lattice, the system is a significant advancement over pre-existing in vitro systems, which typically only allow researchers to study two organ tissues at once. The entire system fits into a spac...
Source: Medgadget - October 26, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Materials Medicine northwestern Source Type: blogs
Higher Serum Klotho Correlates with Lower Systemic Inflammation
The objective of this research is to determine the linkage between soluble Klotho (S-Klotho) level and systemic immune-inflammation index (SII).
Eligible participants with complete information of S-Klotho level and SII were selected from the National Health and Nutrition Examination Surveys (NHANES). Subsequently, weighted multivariate linear regression and subgroup analysis were carried out to evaluate the association. Totally, 11,108 adults with complete data on S-Klotho level, SII and other important covariates were included in final analysis. Multivariate liner regression revealed that high level of S-Klotho wa...
Source: Fight Aging! - October 26, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Rate vs Rhythm Control in Atrial Fibrillation
Rate vs rhythm control as a management strategy in atrial fibrillation has been a long standing topic for debate. Though at one look rhythm control would appear to be the ideal strategy, long term adverse effects of the currently available medications for rhythm control is the often cited down side. AFFIRM [1] and RACE [2] trials were the main reason for the debate as they failed to show any benefit for the rhythm control strategy. AF-CHF trial in those with AF and congestive heart failure also failed to show any advantage for the rhythm control strategy [3]. But there have been important criticisms as well [4]. In AFFIRM...
Source: Cardiophile MD - October 26, 2023 Category: Cardiology Authors: Johnson Francis Tags: ECG / Electrophysiology General Cardiology Source Type: blogs
poem
Op Note XLIOur diagnosis was never in doubt. It was the definitive treatment that remained elusive. Knowing the well-described occasional efficacy of placebo interventions we offered the patient a procedure of last resort. We were down to our last couple of bullets. A proposition strictly in the experimental stages, we told her. A double blinded study. But what other choice did we have? Unbeknownst to her it was a sham surgery. Nothing would be fixed, nothing cut out. We termed it her “special procedure”, as if she were a child being told that grandma was “only sleeping”. We reviewed the risks and benefits, t...
Source: Buckeye Surgeon - October 24, 2023 Category: Surgery Authors: Jeffrey Parks MD FACS Source Type: blogs
Serum Galectin-3 Correlates with Frailty Risk
In this study, we aimed to address the change of Gal-3 levels in human whole blood with frailty. We performed serum biochemical and peripheral blood mononuclear cells (PBMC) microarray analyses in humans to determine the secretory phenotype characteristics of frailty. Furthermore, we used the frail mouse model to study the significantly altered behavioral phenotype and associated secreted Gal-3 levels in blood samples to reveal the Gal-3-dependent inflammatory dysregulation of frailty. (Source: Fight Aging!)
Source: Fight Aging! - October 23, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Klotho Improves Cell Defenses in Brain Cells
This study offers new insights into the roles of Klotho in regulating energy metabolism and the redox state in the brain.
Link: https://doi.org/10.1038/s41598-023-41166-6 (Source: Fight Aging!)
Source: Fight Aging! - October 23, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Sensor Monitors Transplanted Organs for Signs of Rejection
Researchers at Northwestern University have developed a sensor that can monitor transplanted organs for signs of rejection. Patients who receive transplants require immunosuppressive medication to ensure that their body does not reject the transplanted tissue, but this can still happen, sometimes years after the initial transplant. Current methods to monitor for immune rejection involve taking biopsies or monitoring blood markers, but these techniques are invasive and blood markers may not show up until the rejection has already progressed somewhat. This new sensor is thin and flexible and is designed to sit on the surface...
Source: Medgadget - October 19, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Surgery northwestern transplant rejection Source Type: blogs
The dark truth about dialysis
When a colleague recommended a book, I hoped it would be something enjoyable – perhaps a sports anthology, a music biography, or even a novel. Unfortunately, it was about dialysis, the great American scam that it is. As a nephrologist (kidney doctor), I had already come to the same conclusion. Here’s why, supported by Tom
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The dark truth about dialysis originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 19, 2023 Category: General Medicine Authors: Amol Shrikhande, MD Tags: Physician Nephrology Source Type: blogs
How is forward cardiac output affected in MR & TR ?
AV valves exist to divert blood to the outflows when ventricles are contracting. If they leak significantly, obviously there are major consequences. What happens to the net cardiac output when these valves leak?
Clincally , we know ,fatigue is sign of reduced forward cardaic out put , that is more common in MR. But, edema , congestion, muscle fatigue is eqaully if not more common with TR. One importnat diference is MR jet is mainly a hemodynamic trouble in pulmonary circuit while TR jet , has one more component hits on liver function making it metabolic consequnce as well.
Can’t escape, tell us your answer for...
Source: Dr.S.Venkatesan MD - October 18, 2023 Category: Cardiology Authors: dr s venkatesan Tags: Uncategorized atrial functional tr cardiac out put in tr forward cardiac out out meer vs teer mitra clip RESEARCH TOPIC FOR DM CARDIOLOGY tricuspid annulus tricuspid vs mitral regurgitation Source Type: blogs
Imaging of Chromatin Structure as a Basis for an Aging Clock
Researchers here report a novel approach to building an aging clock, a system that can usefully measure biological age, the growing burden of damage and dysfunction. Epigenetic data, usually the status of DNA methylation at various sites on the genome, has been used to construct aging clocks in the past. Epigenetic changes of all sorts alter gene expression by altering the structure of chromatin, folded DNA in the cell nucleus, determining which regions and genes are exposed to transcriptional machinery. Thus why not directly assess changes in the structure of chromatin via microscopy imaging approaches? Researchers have n...
Source: Fight Aging! - October 16, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
