Fight Aging! Newsletter, October 16th 2023
In conclusion, a number of studies have shown that CD4+ Treg cells are crucial in the maintenance of peripheral tolerance and have an important role in the control of atherosclerosis-related inflammation. Therefore, Treg cells are a promising target of major research efforts focused on immune-modulating therapies against atherosclerosis. Developing anti-atherosclerotic Treg-based therapies faces challenges. However, rapid progress in genetic, epigenetic, and molecular aspects of cellular immunology gives hope for a fast-track solution.
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Delivering Senolytic Nanoparticles to Atheroscle...
Source: Fight Aging! - October 15, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A patient ’ s resilience and the challenge of dialysis
After she developed a serious complication, she wanted to know the facts plainly stated. I told her the treatment would change her quality of life; it would be hard but doable. To this, she replied, “Now, don’t bullsh*t me, I don’t like bullsh*tters.” These words were uttered by my resilient, 75-year-old patient undergoing peritoneal dialysis.
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A patient’s resilience and the challenge of dialysis originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - October 14, 2023 Category: General Medicine Authors: Tariq Shaheed, DO Tags: Conditions Nephrology Source Type: blogs
Delivering Senolytic Nanoparticles to Atherosclerotic Plaques in Mice
Cells become senescent in response to stress and damage, and there is a great deal of stress and damage taking place in the toxic environment of an atherosclerotic plaque. These fatty plaques develop with age in blood vessel walls throughout the body. Many contributing factors determine the age of onset and pace of progression of atherosclerosis, but at the center of it all, atherosclerotic plaques form and grow because macrophage cells of the innate immune system fail to keep up with clearance of excess cholesterol delivered from the bloodstream into blood vessel walls. After a plaque becomes established, it contains toxi...
Source: Fight Aging! - October 12, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
Bonus Features, HLTH Edition – October 11, 2023 – Announcements from Best Buy, General Catalyst, Google Cloud, Microsoft, Walgreens, and more
This article will be a roundup of interesting stories, product announcements, partnerships, research studies, company launches, and more from the annual conference. Because there’s so much happening out there at HLTH that we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
Top Headlines
VC firm General Catalyst is creating Health Assurance Transformation Corp., which will partner with 20+ health system partners to guide their transition to value-based care and potentially acquire a health ...
Source: EMR and HIPAA - October 11, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Acuity aidoc athenahealth b.well Best Buy BrightInsight care.ai Circadian Health CLEAR ClearDATA DatosX DAX Copilot DeepScribe Dexcom DUOS Elation Health Evernorth Health Services General Catalyst Google Source Type: blogs
Wednesday Bible Study: Going around in circles
The ridiculous repetition continues, and I ' m not sure what to do about it. This is incredibly boring. They just keep saying the same thing, over and over, at absurd length. I pledged we ' d read the whole damn thing however so in order to keep my word, we just need to plow ahead. Unfortunately, I must warn you, it goes on for quite a while longer in the same circles. This does give us a few popular cliches, e.g. nothing but skin and bones, the skin of my teeth. Whether that makes the whole thing worthwhile I can ' t say. Anyway I ' ll give you two chapters to try to get this over with as soon as possible.19 Then Job...
Source: Stayin' Alive - October 4, 2023 Category: American Health Source Type: blogs
Expert human ECG interpretation and/or the Queen of Hearts could have saved this patient's anterior wall
This is a re-post of an excellent case from 2021. See it again now, along with our new Queen of Hearts functionality. We ' ve come a long way in 2 years! And the pace only quickens.A man in his mid 60s with history of CAD and stents experienced sudden onset epigastric abdominal pain radiating up into his chest at home, waking him from sleep. He called EMS who brought him to the ED. He had active chest pain at the time of triage at 0137 at night, with this triage ECG:What do you think?I sent this ECG, without any text at all, to Dr. Smith, and he replied: " LAD OMI with low certainty. V3 is the one that is convincing. "&nbs...
Source: Dr. Smith's ECG Blog - October 1, 2023 Category: Cardiology Authors: Pendell Source Type: blogs
Wednesday Bible Study: My apologies
This endless yammering is totally frosting my pumpkin. I ' m not sure what to do about it, however, because these chapters are long and it seems like an awful lot to do two of them at once. But what the hell, we have to get this over with. In Ch. 15, Eliphaz castigates Job for complaining to God, basically, and just says, as MacLeish translates it, " In Adam ' s fall we sinned all/We ' re like the flies the creep and crawl/Across the dusty windowpanes, " IIRC, or something like that. In Ch. 16, Job essentially adds the would-be comforters to his afflictions, which is fair enough. What Job doesn ' t know, however, is that t...
Source: Stayin' Alive - September 27, 2023 Category: American Health Source Type: blogs
Implantable Bioreactor for Kidney Cells
Researchers at the University of California San Francisco have developed an implantable bioreactor that may pave the way for artificial kidneys. Dialysis and kidney transplants both have significant disadvantages for patients with kidney failure, and so scientists are trying to develop a lab created kidney that would not require harsh immunosuppression or a donor kidney. This implantable bioreactor may be a step in the right direction, and it includes a type of cell found in the kidney which is protected from the immune system behind a silicon membrane. Blood can flow through the device, and so far the researchers have sho...
Source: Medgadget - September 26, 2023 Category: Medical Devices Authors: Conn Hastings Tags: Medicine Surgery Urology artificial kidney UCSF Source Type: blogs
WHO Report: Tackling Hypertension Could Avert 76M Deaths Globally
Conclusion
Hypertension, often referred to as the “silent killer,” isn’t just a mere health term; it’s a pressing global challenge with vast implications.
As the World Health Organization’s report underscores, controlling high blood pressure is more than a matter of personal health. It’s about potentially averting millions of deaths worldwide by 2050.
It’s heartening to see countries like Canada and South Korea lead the charge with effective treatment programs, offering hope and a pathway for others to follow.
Yet, the contrasting statistics on sodium intake and the p...
Source: The EMT Spot - September 26, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs
The Carenostics Interview
In my other day job of advising companies, I was introduced to Carenostics by my friends at Bayer G4A. This is a super interesting company which is using AI to diagnose serious chronic diseases like kidney disease, asthma, and others much earlier. So far they are working with health systems like Hackensack in NJ and the VA, and have just raised a $5m round. Last week I spoke with father and son team, Kanishka Rao, COO & Bharat Rao, CEO. In particular look out for Bharat’s explanation of what has to go on behind the curtain to make AI become effective. (Source: The Health Care Blog)
Source: The Health Care Blog - September 25, 2023 Category: Consumer Health News Authors: matthew holt Tags: Health Tech AI Bayer G4A Bharat Rao Carenostics chronic kidney disease Kanishka Rao Source Type: blogs
PSA screening: What you need to know [PODCAST]
Subscribe to The Podcast by KevinMD. Catch up on old episodes! Join Stephen Lieberman, a urologist, as we navigate the nuances of prostate care, discussing the evolution of PSA screening, the controversies it has sparked, and the crucial insights that can empower individuals to make informed decisions about their health. Stephen Lieberman is a urologist. He
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PSA screening: What you need to know [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - September 24, 2023 Category: General Medicine Authors: The Podcast by KevinMD Tags: Podcast Oncology/Hematology Source Type: blogs
Bonus Features – September 24, 2023 – 72 percent of patients say affordability is the biggest challenge for paying medical bills
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job.
News and Studies
The American Telemedicine Association released three tools aimed at addressing disparity and inequity in care: Digital Infrastructure Disparities Score and Map, Economic and Social Value-Added Calculator, and a...
Source: EMR and HIPAA - September 24, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT ABOUT Accelecom Accenture Adriana Day AHA AMA Amazon Bedrock Angie Franks Arcadia ATA AVIA Babyscripts Biofourmis Cadence Cedar Censinet CirrusMD CliniComp ClosedLoop Collette Health CrowdStrike Da Source Type: blogs
Fight Aging! Newsletter, September 25th 2023
In conclusion, this individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls.
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Results from Human Clinical Trials Do Not Support Metformin as a Longevity Drug
https://www.fightaging.org/archives/2023/09/results-from-human-clinical-trials-do-not-support-metformin-as-a-longevity-drug/
The SENS Research Fou...
Source: Fight Aging! - September 24, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Medical Control of Hypertension Largely Removes Increased Risk of Dementia
In conclusion, this individual patient data meta-analysis of longitudinal cohort studies found that antihypertensive use was associated with decreased dementia risk compared with individuals with untreated hypertension through all ages in late life. Individuals with treated hypertension had no increased risk of dementia compared with healthy controls. (Source: Fight Aging!)
Source: Fight Aging! - September 20, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
