Optimism for the Future of Amyloid- β Clearance
In today's popular science article, the SENS Research Foundation offers a more rosy picture of the near future of amyloid-β clearance than is the usual fare these days. Amyloids are misfolded or otherwise altered proteins that can aggregate to form solid deposits that disrupt cellular biochemistry. In principle they should all be removed. Their existence is a form of harmful change that takes place with age, and the connections to cell dysfunction are quite clear. The failure of amyloid-β clearance to produce meaningful benefits in Alzheimer's patients has led to some disillusionment, however. Alzheimer's may be a...
Source: Fight Aging! - June 21, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

The inspirational journey of an 82-year-old WWII veteran battling cancer
He was 82 years old when he came into our ER, writhing in excruciating abdominal pain. After an ultrasound and a subsequent CT scan, the devastating diagnosis was revealed—end stage pancreatic and liver cancer. Despite enduring a pain level of 10, he managed to maintain his sense of humor, joking about “biting the bullet.” However, Read more… The inspirational journey of an 82-year-old WWII veteran battling cancer originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 21, 2023 Category: General Medicine Authors: Tags: Conditions Critical Care Nursing Oncology/Hematology Source Type: blogs

What to do about problematic medication taking?
Welcome to another episode of BDI Briefs! Our aim with BDI Briefs is to take a brief look at important issues about the emotional side of diabetes.In this short discussion, Scott, Bill, and Susan explore problematic medication taking and what you can do about it. You may be surprised by some insights – I know I was! Enjoy! And please let us know what you think and what you’d like to hear more about. And remember to subscribe to BDI’s YouTube channel! Detailed show notes and transcript ...
Source: Scott's Diabetes Blog - June 21, 2023 Category: Endocrinology Authors: Scott K. Johnson Tags: Blog Posts Source Type: blogs

Pump Up the Potassium
The element potassium plays a pivotal role in our bodies. It’s found in all our cells, where it regulates their volume and pressure. To do this, our bodies carefully control potassium levels so that the concentration is about 30 times higher inside cells than outside. Potassium works closely with sodium, which regulates the extracellular fluid volume and has a higher concentration outside cells than inside. These concentration differences create an electrochemical gradient, or a membrane potential. Potassium is the primary regulator of the pressure and volume inside cells, and it’s important for nerve transmiss...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 21, 2023 Category: Research Authors: Chrissa Chverchko Tags: Chemistry, Biochemistry and Pharmacology Molecular Structures Cellular Processes Element Proteins Source Type: blogs

Can You Follow A Keto Diet With Hypertension?
Conclusion Navigating the maze of diet and health can indeed be a challenge. Especially when it comes to the trendy keto diet and its potential effects on hypertension. So, where do we land on the question, “Can you follow a keto diet with hypertension?” From the studies we’ve reviewed and the real-life experiences we’ve heard, the answer is a cautious yes. It seems a well-managed keto diet could potentially benefit individuals with hypertension, mainly through weight loss, improved metabolic health, and lower blood sugar levels. However, it’s not a one-size-fits-all approach. The key...
Source: The EMT Spot - June 21, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Will Success in Reversing Aging Shape the Regulatory System to Accommodate It?
A sizable fraction of the therapies produced by the medical industry are, not to put too fine a point on it, garbage. The benefit is not worth the cost of diverting the resources into the full scale production of the drug, versus those resources going towards some better form of medical research and development. Giving a cancer patient an extra month or two of life, reducing fibrosis in the liver by 10% over a year of treatment, incrementally improving mitophagy to half the degree that exercise achieves, and so forth. Small molecule development in particular excels at producing this sort out outcome, as the effects on gene...
Source: Fight Aging! - June 19, 2023 Category: Research Authors: Reason Tags: Longevity Industry Source Type: blogs

Bonus Features – June 18, 2023 – 68% of health systems lack the staff to handle another health crisis, 46% of Americans are using consumer health tech, and more
This article will be a weekly roundup of interesting stories, product announcements, new hires, partnerships, research studies, awards, sales, and more. Because there’s so much happening out there in healthcare IT we aren’t able to cover in our full articles, we still want to make sure you’re informed of all the latest news, announcements, and stories happening to help you better do your job. Reports More than two-thirds of health systems lack the nursing staff to handle a large-scale health crisis, according to an Incredible Health survey. A staggering 94% of executives said the nurse shortage at their organization ...
Source: EMR and HIPAA - June 18, 2023 Category: Information Technology Authors: Brian Eastwood Tags: Healthcare IT Alivia Analytics AnalyticsIQ Barbara Greising Bill Lucia Brightside Health Carenet Health Clarify Advance Clarify Health Clayton Duncan Damyon Smith eClinicalWorks eCW Electronic Caregiver Formlabs Healthcare IT Source Type: blogs

Fight Aging! Newsletter, June 19th 2023
In conclusion, among Swedish middle-aged subjects, nearly two-thirds showed complete fatty degeneration of thymus on CT. Age-Related Dysfunction of Water Homeostasis https://www.fightaging.org/archives/2023/06/age-related-dysfunction-of-water-homeostasis/ Dehydration can be an issue in older people. As in every complex system in the body, the mechanisms by which hydration is regulated become dysfunctional with advancing age. Researchers here look at the brain region responsible for regulating some of the response to dehydration, cataloging altered gene expression in search of the more important mechan...
Source: Fight Aging! - June 18, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

75% Commit To Daily Blood Pressure Checks At Home: Survey Finds
Conclusion: The Way Forward The home blood pressure monitoring initiative by the American Heart Association, supported by the Elevance Health Foundation, aims to help thousands of individuals manage their hypertension better. The high participation and positive feedback from patients underscore the effectiveness of this approach, demonstrating a promising trend towards a healthier future for all. The survey methodology included the participation of adult patients from 11 clinics across nine markets in the U.S. who were diagnosed with high blood pressure. The aim was to identify gaps in knowledge and barriers ...
Source: The EMT Spot - June 16, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

How the U.S. blood pressure validated device listing (VDL) ensures accurate readings and revolutionizes hypertension control
Blood pressure is an important upstream indicator of overall patient health, and high blood pressure can be a precursor to more serious medical conditions like cardiovascular disease, kidney disease, and stroke. Measuring blood pressure frequently is the best way to stay on top of any changes, but as telehealth and at-home monitoring gain in popularity, Read more… How the U.S. blood pressure validated device listing (VDL) ensures accurate readings and revolutionizes hypertension control originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - June 15, 2023 Category: General Medicine Authors: Tags: Conditions Cardiology Source Type: blogs

St. John ’ s Wort: A Hidden Danger For Hypertension?
Conclusion: Navigating The Use Of St. John’s Wort Amidst Hypertension While St. John’s Wort is generally safe for most people, it may pose challenges for individuals managing high blood pressure, especially those on specific medications, such as calcium blockers. Reflecting on Trista Best’s wisdom, informed decision-making and regular healthcare consultations are key to safely traversing the landscape of supplements. As we continually unearth the potentials of these natural remedies, balancing their benefits and risks is fundamental to our health journey. This in-depth understanding helps ensur...
Source: The EMT Spot - June 14, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: News Source Type: blogs

Senolytic Treatments as a Strategy to Improve Immune Function in Late Life
Senescent cells accumulate in tissues throughout the body with age. Cells become senescent constantly throughout life, largely by reaching the Hayflick limit on replication, but a small number due to potentially cancerous mutations, or other forms of damage and stress. Senescent cells are rapidly removed by the immune system in youth, keeping their numbers low, but the balance between creation and destruction is disrupted with aging. There is greater stress, but perhaps more importantly the immune system becomes less efficient, less able to clear senescent cells in a timely fashion. Since senescent cells actively secrete p...
Source: Fight Aging! - June 14, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Career Conversations: Q & A With Physiologist Elimelda Moige Ongeri
Credit: Courtesy of Dr. Elimelda Moige Ongeri. A career path in science is rarely clear cut and linear, which Elimelda Moige Ongeri, Ph.D., can attest adds to its excitement. She went from working in animal reproductive biology to studying proteins involved in inflammation and tissue injury. Dr. Ongeri is also currently dean of the Hairston College of Health and Human Sciences and professor of physiology at North Carolina Agricultural and Technical State University (NC A&T) in Greensboro. In this interview, she shares details of her career, including a change in research focus to human physiology; her goals for the f...
Source: Biomedical Beat Blog - National Institute of General Medical Sciences - June 14, 2023 Category: Research Authors: Chrissa Chverchko Tags: Being a Scientist Profiles Proteins Source Type: blogs

7 Diagnosis And Tests For Low Blood Pressure: A Comprehensive Guide
Conclusion Accurate assessment and recognition of low blood pressure are crucial for effective management. Diagnostic techniques, including medical history assessment, physical examination, ECG, blood tests, Holter monitor, tilt table test, stress test, and imaging tests, help identify underlying causes, assess severity, and rule out complications. Smart blood pressure monitors connected to mobile devices have revolutionized diagnosis and monitoring. These devices provide instant, accurate readings for real-time tracking and analysis. This involves increasing salt intake, staying hydrated, exercising regularly,...
Source: The EMT Spot - June 13, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

ChatGPT Alternatives For Healthcare And Research
ChatGPT has made a name for itself in the world of AI, along with Bard and MedPaLM. Following the success of these first-generation language models, a host of alternatives, including the open-source project Spark NLP for Healthcare, have emerged. Our exploration today focuses on alternative solutions that, while underpinned by the principles of ChatGPT, have potential utility in the healthcare and research sectors. ChatGPT is remarkable, but it does have its drawbacks: a knowledge cut-off in November 2021, unilateral control and updates by OpenAI, an iOS-exclusive mobile app, and API-only integration, which can be quite...
Source: The Medical Futurist - June 13, 2023 Category: Information Technology Authors: Andrea Koncz Tags: TMF Artificial Intelligence in Medicine digital health large language models GPT in healthcare ChatGPT in healthcare AI Source Type: blogs