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Total 1739 results found since Jan 2013.

Carotid dysfunction in senescent female mice is mediated by increased α < sub > 1A < /sub > -adrenoceptor activity and COX-derived vasoconstrictor prostanoids
In conclusion, senescence intensifies vasoconstriction mediated by a1A-adrenergic signaling in the carotid of female mice by mechanisms involving increased iCa+2 and release of cyclooxygenase-derived prostanoids.PMID:36705993 | DOI:10.1152/ajpheart.00495.2022
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Tiago J Costa Paula R Barros Diego A Duarte J úlio A Silva-Neto Sara Cristina Hott Thamyris Santos-Silva Claudio M Costa-Neto Felipe V Gomes Eliana H Akamine Cameron G McCarthy Francesc Jim énez-Altayó Ana Paula Dantas Rita C Tostes Source Type: research

Impact of Right Ventricular Reserve on Exercise Capacity and Quality of Life in Patients with Left Ventricular Assist Device
Am J Physiol Heart Circ Physiol. 2023 Jan 27. doi: 10.1152/ajpheart.00626.2022. Online ahead of print.ABSTRACTAlthough measuring right ventricular (RV) function during exercise is more informative than assessing it at rest, the relationship between RV reserve function, exercise capacity, and health-related quality-of-life (HRQoL) in patients with left ventricular assist devices (LVAD) remains unresolved. We aimed to investigate whether RV reserve assessed by the change in RV stroke work index (RVSWI) during exercise is correlated with exercise capacity and HRQoL in patients with LVAD. We prospectively assessed 24 consecuti...
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Sakae Takenaka Takuma Sato Toshiyuki Nagai Kazunori Omote Yuta Kobayashi Kiwamu Kamiya Takao Konishi Atsushi Tada Yoshifumi Mizuguchi Yuki Takahashi Seiichiro Naito Kohei Saiin Suguru Ishizaka Satoru Wakasa Toshihisa Anzai Source Type: research

Carotid dysfunction in senescent female mice is mediated by increased α < sub > 1A < /sub > -adrenoceptor activity and COX-derived vasoconstrictor prostanoids
In conclusion, senescence intensifies vasoconstriction mediated by a1A-adrenergic signaling in the carotid of female mice by mechanisms involving increased iCa+2 and release of cyclooxygenase-derived prostanoids.PMID:36705993 | DOI:10.1152/ajpheart.00495.2022
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Tiago J Costa Paula R Barros Diego A Duarte J úlio A Silva-Neto Sara Cristina Hott Thamyris Santos-Silva Claudio M Costa-Neto Felipe V Gomes Eliana H Akamine Cameron G McCarthy Francesc Jim énez-Altayó Ana Paula Dantas Rita C Tostes Source Type: research

Impact of Right Ventricular Reserve on Exercise Capacity and Quality of Life in Patients with Left Ventricular Assist Device
Am J Physiol Heart Circ Physiol. 2023 Jan 27. doi: 10.1152/ajpheart.00626.2022. Online ahead of print.ABSTRACTAlthough measuring right ventricular (RV) function during exercise is more informative than assessing it at rest, the relationship between RV reserve function, exercise capacity, and health-related quality-of-life (HRQoL) in patients with left ventricular assist devices (LVAD) remains unresolved. We aimed to investigate whether RV reserve assessed by the change in RV stroke work index (RVSWI) during exercise is correlated with exercise capacity and HRQoL in patients with LVAD. We prospectively assessed 24 consecuti...
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Sakae Takenaka Takuma Sato Toshiyuki Nagai Kazunori Omote Yuta Kobayashi Kiwamu Kamiya Takao Konishi Atsushi Tada Yoshifumi Mizuguchi Yuki Takahashi Seiichiro Naito Kohei Saiin Suguru Ishizaka Satoru Wakasa Toshihisa Anzai Source Type: research

Carotid dysfunction in senescent female mice is mediated by increased α < sub > 1A < /sub > -adrenoceptor activity and COX-derived vasoconstrictor prostanoids
In conclusion, senescence intensifies vasoconstriction mediated by a1A-adrenergic signaling in the carotid of female mice by mechanisms involving increased iCa+2 and release of cyclooxygenase-derived prostanoids.PMID:36705993 | DOI:10.1152/ajpheart.00495.2022
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Tiago J Costa Paula R Barros Diego A Duarte J úlio A Silva-Neto Sara Cristina Hott Thamyris Santos-Silva Claudio M Costa-Neto Felipe V Gomes Eliana H Akamine Cameron G McCarthy Francesc Jim énez-Altayó Ana Paula Dantas Rita C Tostes Source Type: research

Impact of Right Ventricular Reserve on Exercise Capacity and Quality of Life in Patients with Left Ventricular Assist Device
Am J Physiol Heart Circ Physiol. 2023 Jan 27. doi: 10.1152/ajpheart.00626.2022. Online ahead of print.ABSTRACTAlthough measuring right ventricular (RV) function during exercise is more informative than assessing it at rest, the relationship between RV reserve function, exercise capacity, and health-related quality-of-life (HRQoL) in patients with left ventricular assist devices (LVAD) remains unresolved. We aimed to investigate whether RV reserve assessed by the change in RV stroke work index (RVSWI) during exercise is correlated with exercise capacity and HRQoL in patients with LVAD. We prospectively assessed 24 consecuti...
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Sakae Takenaka Takuma Sato Toshiyuki Nagai Kazunori Omote Yuta Kobayashi Kiwamu Kamiya Takao Konishi Atsushi Tada Yoshifumi Mizuguchi Yuki Takahashi Seiichiro Naito Kohei Saiin Suguru Ishizaka Satoru Wakasa Toshihisa Anzai Source Type: research

Carotid dysfunction in senescent female mice is mediated by increased α < sub > 1A < /sub > -adrenoceptor activity and COX-derived vasoconstrictor prostanoids
In conclusion, senescence intensifies vasoconstriction mediated by a1A-adrenergic signaling in the carotid of female mice by mechanisms involving increased iCa+2 and release of cyclooxygenase-derived prostanoids.PMID:36705993 | DOI:10.1152/ajpheart.00495.2022
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Tiago J Costa Paula R Barros Diego A Duarte J úlio A Silva-Neto Sara Cristina Hott Thamyris Santos-Silva Claudio M Costa-Neto Felipe V Gomes Eliana H Akamine Cameron G McCarthy Francesc Jim énez-Altayó Ana Paula Dantas Rita C Tostes Source Type: research

Impact of Right Ventricular Reserve on Exercise Capacity and Quality of Life in Patients with Left Ventricular Assist Device
Am J Physiol Heart Circ Physiol. 2023 Jan 27. doi: 10.1152/ajpheart.00626.2022. Online ahead of print.ABSTRACTAlthough measuring right ventricular (RV) function during exercise is more informative than assessing it at rest, the relationship between RV reserve function, exercise capacity, and health-related quality-of-life (HRQoL) in patients with left ventricular assist devices (LVAD) remains unresolved. We aimed to investigate whether RV reserve assessed by the change in RV stroke work index (RVSWI) during exercise is correlated with exercise capacity and HRQoL in patients with LVAD. We prospectively assessed 24 consecuti...
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Sakae Takenaka Takuma Sato Toshiyuki Nagai Kazunori Omote Yuta Kobayashi Kiwamu Kamiya Takao Konishi Atsushi Tada Yoshifumi Mizuguchi Yuki Takahashi Seiichiro Naito Kohei Saiin Suguru Ishizaka Satoru Wakasa Toshihisa Anzai Source Type: research

Carotid dysfunction in senescent female mice is mediated by increased α < sub > 1A < /sub > -adrenoceptor activity and COX-derived vasoconstrictor prostanoids
In conclusion, senescence intensifies vasoconstriction mediated by a1A-adrenergic signaling in the carotid of female mice by mechanisms involving increased iCa+2 and release of cyclooxygenase-derived prostanoids.PMID:36705993 | DOI:10.1152/ajpheart.00495.2022
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Tiago J Costa Paula R Barros Diego A Duarte J úlio A Silva-Neto Sara Cristina Hott Thamyris Santos-Silva Claudio M Costa-Neto Felipe V Gomes Eliana H Akamine Cameron G McCarthy Francesc Jim énez-Altayó Ana Paula Dantas Rita C Tostes Source Type: research

Impact of Right Ventricular Reserve on Exercise Capacity and Quality of Life in Patients with Left Ventricular Assist Device
Am J Physiol Heart Circ Physiol. 2023 Jan 27. doi: 10.1152/ajpheart.00626.2022. Online ahead of print.ABSTRACTAlthough measuring right ventricular (RV) function during exercise is more informative than assessing it at rest, the relationship between RV reserve function, exercise capacity, and health-related quality-of-life (HRQoL) in patients with left ventricular assist devices (LVAD) remains unresolved. We aimed to investigate whether RV reserve assessed by the change in RV stroke work index (RVSWI) during exercise is correlated with exercise capacity and HRQoL in patients with LVAD. We prospectively assessed 24 consecuti...
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 27, 2023 Category: Physiology Authors: Sakae Takenaka Takuma Sato Toshiyuki Nagai Kazunori Omote Yuta Kobayashi Kiwamu Kamiya Takao Konishi Atsushi Tada Yoshifumi Mizuguchi Yuki Takahashi Seiichiro Naito Kohei Saiin Suguru Ishizaka Satoru Wakasa Toshihisa Anzai Source Type: research

Ensemble averaging for categorical variables: Validation study of imputing lost data in 24-h recorded postures of inpatients
Acceleration sensors are widely used in consumer wearable devices and smartphones. Postures estimated from recorded accelerations are commonly used as features indicating the activities of patients in medical studies. However, recording for over 24 h is more likely to result in data losses than recording for a few hours, especially when consumer-grade wearable devices are used. Here, to impute postures over a period of 24 h, we propose an imputation method that uses ensemble averaging. This method outputs a time series of postures over 24 h with less lost data by calculating the ratios of postures taken at the same time...
Source: Frontiers in Physiology - January 26, 2023 Category: Physiology Source Type: research

Rehabilitation assisted by Space technology —A SAHC approach in immobilized patients—A case of stroke
Discussion: These alterations were attributed to the short-arm human centrifuge intervention. This case study provides novel evidence supporting the use of the short-arm human centrifuge as a promising therapeutic strategy in patients with restricted mobility, with application to astronauts with long-term muscle disuse in space.
Source: Frontiers in Physiology - January 18, 2023 Category: Physiology Source Type: research

Evaluation of blood-brain barrier integrity by the analysis of dynamic contrast-enhanced MRI - a comparison of quantitative and semi-quantitative methods
Physiol Res. 2022 Dec 31;71(S2):S259-S275.ABSTRACTDisruption of the blood-brain barrier (BBB) is a key feature of various brain disorders. To assess its integrity a parametrization of dynamic magnetic resonance imaging (DCE MRI) with a contrast agent (CA) is broadly used. Parametrization can be done quantitatively or semi-quantitatively. Quantitative methods directly describe BBB permeability but exhibit several drawbacks such as high computation demands, reproducibility issues, or low robustness. Semi-quantitative methods are fast to compute, simply mathematically described, and robust, however, they do not describe the s...
Source: Physiological Research - January 17, 2023 Category: Physiology Authors: D Kala V Šulc A Ol šerová J Svoboda Y Prysiazhniuk A Po šusta M Kyn čl J Šanda A Tomek J Ot áhal Source Type: research

Cardiovascular changes during phototherapy in newborns
Physiol Res. 2022 Dec 31;71(S2):S179-S186.ABSTRACTPhototherapy is the most effective non-invasive method of neonatal hyperbilirubinemia treatment. Application of this method can be associated with side effects including changes in the cardiovascular system. During phototherapy, the primary effects in the cardiovascular system include cutaneous vasodilation leading to skin hyperperfusion and subsequent redistribution of blood. The increased blood flow through the skin is associated with increased transepidermal water loss. Further effects include an increase in cerebral blood flow. Redistribution of blood to the cutaneous b...
Source: Physiological Research - January 17, 2023 Category: Physiology Authors: K Javorka L Nandr ážiová Z Uhr íková B Czippelov á K Ma ťašová M Javorka M Zibolen Source Type: research