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Total 1739 results found since Jan 2013.
Cerebral multimodality monitoring in adult neurocritical care patients with acute brain injury: A narrative review
Cerebral multimodality monitoring (MMM) is, even with a general lack of Class I evidence, increasingly recognized as a tool to support clinical decision-making in the neuroscience intensive care unit (NICU). However, literature and guidelines have focused on unimodal signals in a specific form of acute brain injury. Integrating unimodal signals in multiple signal monitoring is the next step for clinical studies and patient care. As such, we aimed to investigate the recent application of MMM in studies of adult patients with traumatic brain injury (TBI), subarachnoid hemorrhage (SAH), intracerebral hemorrhage (ICH), acute i...
Source: Frontiers in Physiology - December 1, 2022 Category: Physiology Source Type: research
Effects of kinesio taping therapy on gait and surface electromyography in stroke patients with hemiplegia
Conclusion: KT treatment is effective in altering gait and SEMG characteristics in stroke patients with hemiplegia.
Source: Frontiers in Physiology - November 30, 2022 Category: Physiology Source Type: research
Treating exertional heat stroke: Limited understanding of the female response to cold water immersion
According to an expansive body of research and best practice statements, whole-body cold water immersion is the gold standard treatment for exertional heat stroke. However, as this founding evidence was predominantly drawn from males, the current guidelines for treatment are being applied to women without validation. Given the recognised differences in thermal responses experienced by men and women, all-encompassing exertional heat stroke treatment advice may not effectively protect both sexes. In fact, recent evidence suggests that hyperthermic women cool faster than hyperthermic men during cold water immersion. This rais...
Source: Frontiers in Physiology - November 25, 2022 Category: Physiology Source Type: research
V ˙O2 kinetics and tethered strength influence the 200-m front crawl stroke kinematics and speed in young male swimmers
Conclusion: The ability of reaching a high level of V˙O2 fast is essential for a swimmer’s energy production at short- and middle-distance events. Reaching a high level of V˙O2 significantly determines tethered strength and swimming kinematics. The level of V˙O2 influences the maintenance of a proper pulling force and the stroke technique of front crawl swimming in young male swimmers.
Source: Frontiers in Physiology - November 24, 2022 Category: Physiology Source Type: research
Hypoxia induces purinergic receptor signaling to disrupt endothelial barrier function
Blood-brain-barrier permeability is regulated by endothelial junctional proteins and is vital in limiting access to and from the blood to the CNS. When stressed, several cells, including endothelial cells, can release nucleotides like ATP and ADP that signal through purinergic receptors on these cells to disrupt BBB permeability. While this process is primarily protective, unrestricted, uncontrolled barrier disruption during injury or inflammation can lead to serious neurological consequences. Purinergic receptors are broadly classified into two families: the P1 adenosine and P2 nucleotide receptors. The P2 receptors are f...
Source: Frontiers in Physiology - November 21, 2022 Category: Physiology Source Type: research
Microwave-induced thermoacoustic imaging for the early detection of canine intracerebral hemorrhage
Conclusion: This is the first experimental study to explore the use of TAI in the detection of intracerebral hemorrhage in large live animals (canine). The results indicated that TAI could detect canine intracerebral hemorrhage in the early stage and has the potential to be a rapid and noninvasive method for the detection of intracerebral hemorrhage in humans.
Source: Frontiers in Physiology - November 16, 2022 Category: Physiology Source Type: research
Detrimental effects of transient cerebral ischemia on middle cerebral artery mitochondria in female rats
Am J Physiol Heart Circ Physiol. 2022 Nov 11. doi: 10.1152/ajpheart.00346.2022. Online ahead of print.ABSTRACTMitochondrial numbers and dynamics in brain blood vessels differ between young male and female rats under physiological conditions, but how these differences are affected by stroke is unclear. In males, we found that mitochondrial numbers, possibly due to mitochondrial fission, in large middle cerebral arteries (MCAs) increased following transient middle cerebral artery occlusion (tMCAO). However, mitochondrial effects of stroke on MCAs of female rats have not been studied. To address this disparity, we conducted m...
Source: American Journal of Physiology. Heart and Circulatory Physiology - November 11, 2022 Category: Physiology Authors: Ibolya Rutkai Ivan Merdzo Sanjay Wunnava Catherine McNulty Partha K Chandra Prasad V Katakam David W Busija Source Type: research
Automated model calibration with parallel MCMC: Applications for a cardiovascular system model
Computational physiological models continue to increase in complexity, however, the task of efficiently calibrating the model to available clinical data remains a significant challenge. One part of this challenge is associated with long calibration times, which present a barrier for the routine application of model-based prediction in clinical practice. Another aspect of this challenge is the limited available data for the unique calibration of complex models. Therefore, to calibrate a patient-specific model, it may be beneficial to verify that task-specific model predictions have acceptable uncertainty, rather than requir...
Source: Frontiers in Physiology - November 9, 2022 Category: Physiology Source Type: research
Body mass index, but not sex, influences exertional heat stroke risk in young healthy men and women
Am J Physiol Regul Integr Comp Physiol. 2022 Nov 7. doi: 10.1152/ajpregu.00168.2022. Online ahead of print.ABSTRACTExertional heat stroke (EHS) remains a persistent threat for individuals working or playing in the heat, including athletes, the military and emergency service personnel. However, influence of biological sex and/or body mass index (BMI) on the risk of EHS remain poorly understood. The purpose of this study was to retrospectively assess the influence of sex and BMI on risk of EHS in the active duty U.S. Army. We analyzed data from 2016-2021, using a matched case-control approach, where each individual with a di...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - November 7, 2022 Category: Physiology Authors: Gabrielle E W Giersch Kathryn M Taylor Aaron R Caldwell Nisha Charkoudian Source Type: research
