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Total 1739 results found since Jan 2013.
Polygenic genetic variation affecting antibody formation underlies hypertensive renal injury in the Stroke-Prone Spontaneously Hypertensive Rat
Am J Physiol Renal Physiol. 2023 Jul 13. doi: 10.1152/ajprenal.00058.2023. Online ahead of print.ABSTRACTMost SHR lines are resistant to hypertensive renal disease. However, the SHR-A3 line (stroke-prone SHR or SHRSP) experiences end organ injury (EOI) and provides a model that can be used to uncover genetic causation. In the present study we have generated a congenic line in which three distinct disease loci in SHR-A3 are concurrently replaced with the homologous loci from an injury-resistant SHR line (SHR-B2). Verification that all three loci were homozygously replaced in this triple congenic line (SHR-A3(Trip B2)) while...
Source: American Journal of Physiology. Renal Physiology - July 13, 2023 Category: Physiology Authors: Isha S Dhande Yaming Zhu Aniket S Joshi M John Hicks Michael C Braun Peter A Doris Source Type: research
Using the ear photoplethysmographic waveform as an early indicator of central hypovolemia in healthy volunteers utilizing LBNP induced hypovolemia model
Objective. To study the photoplethysmographic (PPG) waveforms of different locations (ear and finger) during lower body negative pressure (LBNP) induced hypovolemia. Then, to determine whether the PPG waveform can be used to detect hypovolemia during the early stage of LBNP. Approach. 36 healthy volunteers were recruited for progressive LBNP induced hypovolemia, with an endpoint of −60 mmHg or development of hypoperfusion symptoms, whichever comes first. Subjects tolerating the entire protocol without symptoms were designated as high tolerance (HT), while symptomatic subjects were designated as low tolerance (LT). Subjec...
Source: Physiological Measurement - July 9, 2023 Category: Physiology Authors: Anna-Maria Eid, Mohamed Elgamal, Antonio Gonzalez-Fiol, Kirk H Shelley, Hau-Tieng Wu and Aymen Awad Alian Source Type: research
Pregnancy-Associated Takotsubo Cardiomyopathy Hospitalizations in the United States
Am J Physiol Heart Circ Physiol. 2023 Jul 7. doi: 10.1152/ajpheart.00262.2023. Online ahead of print.ABSTRACTTakotsubo cardiomyopathy (TCM) is most common in postmenopausal women aged ≥ 50 years but also affects pregnant individuals. However, there are no national estimates on the prevalence, timing of occurrence, correlates, and outcomes of Pregnancy-associated TCM. Using the Nationwide Inpatient Sample (NIS: 2016-2020), we describe rates of pregnancy-associated TCM hospitalizations among 13 - 49 years old pregnant individuals in the United States by selected demographic, behavioral, hospital, and clinical characteristi...
Source: American Journal of Physiology. Heart and Circulatory Physiology - July 7, 2023 Category: Physiology Authors: Mulubrhan F Mogos Soojung Ahn James M Muchira Sarah Osmundson Mariann R Piano Source Type: research
Training drills in high performance badminton —effects of interval duration on internal and external loads
Conclusion: Anaerobic metabolic stimulus increases while running distance and velocity decrease, in case of longer interval durations. Even though there was no impact on stroke precision, extending the intervals beyond 30 s might impair external training load and skill performance. Consequently, interval duration should be defined carefully depending on the training goals.
Source: Frontiers in Physiology - June 30, 2023 Category: Physiology Source Type: research
Using Statistical Parametric Mapping as a statistical method for more detailed insights in swimming: a systematic review
Swimming is a time-based sport and hence strongly dependent from velocity. Most studies about swimming refer to velocity as discrete variable, i.e., 0-D (no time dimension). However, it was argued that using swimming velocity as a continuous variable (1-D, with time dimension) with Statistical Parametric Mapping (SPM) can bring deeper and detailed insights about swimming performance. Therefore, the aim of this study was to perform a systematic review about the current body of knowledge of using Statistical Parametric Mapping in a swimming context. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRIS...
Source: Frontiers in Physiology - June 29, 2023 Category: Physiology Source Type: research
