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Total 1739 results found since Jan 2013.

A Genetic Variant of miR-34a Contributes to Susceptibility of Ischemic Stroke Among Chinese Population
This study was supported by National Natural Science Foundation of China (Nos. 81560552, 81260234), Natural Science Foundation of Guangxi Zhuang Autonomous Region (CN) (2017JJA180826), Innovation Project of Guangxi Graduate Education (CN) (201601009) and Key Laboratory Open Project Fund of Guangxi Zhuang Autonomous Region (CN) (kfkt20160064). Conflict of Interest Statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Supplementary Material The Supplementary Material for this article can be fou...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Distinct plasma proteomic changes in male and female African American stroke patients.
CONCLUSION: Plasma proteins that differ in quantities between stroke patients and controls were readily detected using a simple proteomic approach. Sex-dependent changes and changes that have not been reported for African American stroke patients offer potentially novel biomarkers for stroke in this underserved population. PMID: 31149323 [PubMed]
Source: International Journal of Physiology, Pathophysiology and Pharmacology - June 4, 2019 Category: Physiology Tags: Int J Physiol Pathophysiol Pharmacol Source Type: research

Patient-Specific Modeling Could Predict Occurrence of Pediatric Stroke
Moyamoya disease (MMD) is a progressive steno-occlusive cerebrovascular disease leading to recurrent stroke. There is a lack of reliable biomarkers to identify unilateral stroke MMD patients who are likely to progress to bilateral disease and experience subsequent contralateral stroke(s). We hypothesized that local hemodynamics are predictive of future stroke and set out to noninvasively assess this stroke risk in pediatric MMD patients. MR and X-ray angiography imaging were utilized to reconstruct patient-specific models of the circle of Willis of six pediatric MMD patients who had previous strokes, along with a control s...
Source: Frontiers in Physiology - February 28, 2022 Category: Physiology Source Type: research

Circulating leucocytes perpetuate stroke ‐induced aortic dysfunction
New Findings What is the central question of this study? Does a stroke event influence aortic endothelial function; and what is the role of peripheral circulating leucocytes in stroke on the vascular reactivity of the aorta? What is the main finding and its importance? In vitro co‐culture experiments demonstrated that aortic endothelium‐dependent relaxation was impaired when rat aortic rings were co‐cultured with leucocytes stimulated with serum from stroke patients. Impaired vascular reactivity was not observed in aortic rings without leucocytes stimulated with serum from stroke patients or age‐matched control pa...
Source: Experimental Physiology - September 2, 2017 Category: Physiology Authors: Shinichi Asano, Grant C. O'Connell, Kent C. Lemaster, Evan R. DeVallance, Kayla W. Branyan, James W. Simpkins, Jefferson C. Frisbee, Taura L. Barr, Paul D. Chantler Tags: Research Paper Source Type: research

Circulating leukocytes perpetuate stroke ‐induced aortic dysfunction
This article is protected by copyright. All rights reserved
Source: Experimental Physiology - July 1, 2017 Category: Physiology Authors: Shinichi Asano, Grant C. O'Connell, Kent C. Lemaster, Evan R. DeVallance, Kayla W. Branyan, James W. Simpkins, Jefferson C. Frisbee, Taura L. Barr, Paul D. Chantler Tags: Research Paper Source Type: research

Stroke-GAN Painter: Learning to paint artworks using stroke-style generative adversarial networks
AbstractIt is a challenging task to teach machines to paint like human artists in a stroke-by-stroke fashion. Despite advances in stroke-based image rendering and deep learning-based image rendering, existing painting methods have limitations: they (i) lack flexibility to choose different art-style strokes, (ii) lose content details of images, and (iii) generate few artistic styles for paintings. In this paper, we propose a stroke-style generative adversarial network, called Stroke-GAN, to solve the first two limitations. Stroke-GAN learns styles of strokes from different stroke-style datasets, so can produce diverse strok...
Source: European Journal of Applied Physiology - August 17, 2023 Category: Physiology Source Type: research

Whole genome transcriptomic reveals heat stroke molecular signatures in humans
This article is protected by copyright. All rights reserved.PMID:36951421 | DOI:10.1113/JP284031
Source: The Journal of Physiology - March 23, 2023 Category: Physiology Authors: Abderrezak Bouchama Mamoon Rashid Shuja Shafi Malik Saeed Almahri Yara Yassin Mashan Abdullah Nour Abdulmalek Fuad Maashi Abdulaziz Mashi Altaf Khan Badriah Alotaibi Cynthia Lehe Sameer Mohammad Haitham Alkadi Deemah Al Waadani Saber Yezli Source Type: research

Interactions between the Autonomic Nervous System and the Immune System after Stroke
Compr Physiol. 2022 Jun 29;12(3):3665-3704. doi: 10.1002/cphy.c210047.ABSTRACTAcute stroke is one of the leading causes of morbidity and mortality worldwide. Stroke-induced immune-inflammatory response occurs in the perilesion areas and the periphery. Although stroke-induced immunosuppression may alleviate brain injury, it hinders brain repair as the immune-inflammatory response plays a bidirectional role after acute stroke. Furthermore, suppression of the systemic immune-inflammatory response increases the risk of life-threatening systemic bacterial infections after acute stroke. Therefore, it is essential to explore the ...
Source: Comprehensive Physiology - June 29, 2022 Category: Physiology Authors: Li Zhu Leo Huang Anh Le Tom J Wang Jiewen Zhang Xuemei Chen Junmin Wang Jian Wang Chao Jiang Source Type: research