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Total 1739 results found since Jan 2013.
Body mass index, but not sex, influences exertional heat stroke risk in young healthy men and women
Am J Physiol Regul Integr Comp Physiol. 2022 Nov 7. doi: 10.1152/ajpregu.00168.2022. Online ahead of print.ABSTRACTExertional heat stroke (EHS) remains a persistent threat for individuals working or playing in the heat, including athletes, the military and emergency service personnel. However, influence of biological sex and/or body mass index (BMI) on the risk of EHS remain poorly understood. The purpose of this study was to retrospectively assess the influence of sex and BMI on risk of EHS in the active duty U.S. Army. We analyzed data from 2016-2021, using a matched case-control approach, where each individual with a di...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - November 7, 2022 Category: Physiology Authors: Gabrielle E W Giersch Kathryn M Taylor Aaron R Caldwell Nisha Charkoudian Source Type: research
Tonic extracellular glutamate and ischemia: Glutamate antiporter system x < sub > c < /sub > < sup > - < /sup > regulates anoxic depolarization in hippocampus
This article is protected by copyright. All rights reserved.PMID:36321247 | DOI:10.1113/JP283880
Source: The Journal of Physiology - November 2, 2022 Category: Physiology Authors: Bradley S Heit Alex Chu Abhay Sane David E Featherstone Thomas J Park John Larson Source Type: research
Functional compliance and protective stiffness: cross-veins in the hind wing of locust Locusta migratoria
This study evaluated the cross-veins of the locust hind wing using uniaxial tensile tester, scanning electron microscope, and finite element methods. Four cross-vein types were identified at different locations on the hind wing, including periodical semi- and full-ellipsoidal humps and periodical semi- and full-conical humps. The four cross-veins showed similar tensile stiffness but differed in bending compliance. We suggest that the mechanical properties of the four cross-veins can be attributed to their physiological functions. This study elucidates cross-veins of locust hind wing and contributes our understanding of the...
Source: Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology - October 27, 2022 Category: Physiology Source Type: research
Identification of therapeutic targets in a murine model of severe exertional heat stroke
Am J Physiol Regul Integr Comp Physiol. 2022 Oct 25. doi: 10.1152/ajpregu.00150.2022. Online ahead of print.ABSTRACTExertional heat stroke (EHS) is a potentially lethal condition resulting from high core body temperatures (TC) in combination with a systemic inflammatory response syndrome (SIRS) with varying degrees of severity across victims, and limited understanding of the underlying mechanism(s). We established a mouse model of severe EHS in an effort to identify mechanisms of hyperthermia / inflammation that may be responsible for organ damage. Mice were forced to run on a motorized wheel in a 37.5°C chamber until los...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - October 25, 2022 Category: Physiology Authors: Kentaro Oki Chloe G Henderson Shauna M Ward Jermaine A Ward Mark L Plamper Thomas A Mayer Aaron R Caldwell Lisa R Leon Source Type: research
Neuromotor deficits and altered physiological responses to repeated exertional heat stroke exposures in mice
In conclusion, exposure to a second EHS after two weeks, leads to increased exercise times in the heat, symptom limitation at a lower Tc,max, and greater deficits in neuromotor and behavioral function during recovery.PMID:36279505 | DOI:10.1152/ajpregu.00152.2022
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - October 24, 2022 Category: Physiology Authors: Jamal M Alzahrani Kevin O Murray Bryce J Gambino Christian K Garcia Laila H Sheikh Kevin J Cusack Orlando Laitano Thomas L Clanton Source Type: research
The Essential Role of Arterial Pulse in Venous Return
Am J Physiol Regul Integr Comp Physiol. 2022 Oct 24. doi: 10.1152/ajpregu.00204.2022. Online ahead of print.ABSTRACTThe close proximity of arteries and veins is a well-known anatomical finding documented in the extremities of all vertebrates. However, the physiological consequences of this arrangement are rarely given proper consideration, nor are they covered in the textbook list of mechanisms that aid blood flow. We hypothesized that arterial pressure pulsations can significantly increase blood flow in the adjacent valve-containing vein segments. To demonstrate the existence of this mechanism, 10-15-cm sections of the bo...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - October 24, 2022 Category: Physiology Authors: Narine M LeFevre Narine Sarvazyan Source Type: research
Neuromotor deficits and altered physiological responses to repeated exertional heat stroke exposures in mice
In conclusion, exposure to a second EHS after two weeks, leads to increased exercise times in the heat, symptom limitation at a lower Tc,max, and greater deficits in neuromotor and behavioral function during recovery.PMID:36279505 | DOI:10.1152/ajpregu.00152.2022
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - October 24, 2022 Category: Physiology Authors: Jamal M Alzahrani Kevin O Murray Bryce J Gambino Christian K Garcia Laila H Sheikh Kevin J Cusack Orlando Laitano Thomas L Clanton Source Type: research
