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Total 1739 results found since Jan 2013.
Cardiovascular changes during phototherapy in newborns
Physiol Res. 2022 Dec 31;71(S2):S179-S186.ABSTRACTPhototherapy is the most effective non-invasive method of neonatal hyperbilirubinemia treatment. Application of this method can be associated with side effects including changes in the cardiovascular system. During phototherapy, the primary effects in the cardiovascular system include cutaneous vasodilation leading to skin hyperperfusion and subsequent redistribution of blood. The increased blood flow through the skin is associated with increased transepidermal water loss. Further effects include an increase in cerebral blood flow. Redistribution of blood to the cutaneous b...
Source: Physiological Research - January 17, 2023 Category: Physiology Authors: K Javorka L Nandr ážiová Z Uhr íková B Czippelov á K Ma ťašová M Javorka M Zibolen Source Type: research
Evaluation of blood-brain barrier integrity by the analysis of dynamic contrast-enhanced MRI - a comparison of quantitative and semi-quantitative methods
Physiol Res. 2022 Dec 31;71(S2):S259-S275.ABSTRACTDisruption of the blood-brain barrier (BBB) is a key feature of various brain disorders. To assess its integrity a parametrization of dynamic magnetic resonance imaging (DCE MRI) with a contrast agent (CA) is broadly used. Parametrization can be done quantitatively or semi-quantitatively. Quantitative methods directly describe BBB permeability but exhibit several drawbacks such as high computation demands, reproducibility issues, or low robustness. Semi-quantitative methods are fast to compute, simply mathematically described, and robust, however, they do not describe the s...
Source: Physiological Research - January 17, 2023 Category: Physiology Authors: D Kala V Šulc A Ol šerová J Svoboda Y Prysiazhniuk A Po šusta M Kyn čl J Šanda A Tomek J Ot áhal Source Type: research
Cardiovascular changes during phototherapy in newborns
Physiol Res. 2022 Dec 31;71(S2):S179-S186.ABSTRACTPhototherapy is the most effective non-invasive method of neonatal hyperbilirubinemia treatment. Application of this method can be associated with side effects including changes in the cardiovascular system. During phototherapy, the primary effects in the cardiovascular system include cutaneous vasodilation leading to skin hyperperfusion and subsequent redistribution of blood. The increased blood flow through the skin is associated with increased transepidermal water loss. Further effects include an increase in cerebral blood flow. Redistribution of blood to the cutaneous b...
Source: Physiological Research - January 17, 2023 Category: Physiology Authors: K Javorka L Nandr ážiová Z Uhr íková B Czippelov á K Ma ťašová M Javorka M Zibolen Source Type: research
Habituation of the stress response multiplex to repeated cold pressor exposure
Humans show remarkable habituation to aversive events as reflected by changes of both subjective report and objective measures of stress. Although much experimental human research focuses on the effects of stress, relatively little is known about the cascade of physiological and neural responses that contribute to stress habituation. The cold pressor test (CPT) is a common method for inducing acute stress in human participants in the laboratory; however, there are gaps in our understanding of the global state changes resulting from this stress-induction technique and how these responses change over multiple exposures. Here...
Source: Frontiers in Physiology - January 10, 2023 Category: Physiology Source Type: research
Exaggerated exercise pressor reflex in male UC Davis type 2 diabetic rats is due to the pathophysiology of the disease and not aging
Discussion: Our findings suggest that the exaggerated exercise pressor reflex and mechanoreflex seen in T2DM are due to the pathophysiology of the disease and not aging.
Source: Frontiers in Physiology - January 10, 2023 Category: Physiology Source Type: research
Age at Natural Menopause Impacts Cerebrovascular Reactivity and Brain Structure
Am J Physiol Regul Integr Comp Physiol. 2023 Jan 9. doi: 10.1152/ajpregu.00228.2022. Online ahead of print.ABSTRACTMenopause is associated with adverse changes in vascular health coinciding with an increased risk of stroke and vascular cognitive impairment. However, there is significant variation in the age at menopause. The present study examined how the age at natural menopause impacts cerebrovascular reactivity and structural biomarkers of brain aging. Thirty-five healthy postmenopausal women were classified as early onset menopause (Early; n = 19, age at menopause: 47 ± 2 years) or later onset menopause (Late; n = 16,...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - January 9, 2023 Category: Physiology Authors: M Erin Moir Adam T Corkery Katherine A Senese Kathleen B Miller Andrew G Pearson Nicole A Loggie Anna J Howery Sarean H A Gaynor-Metzinger Karly A Cody Laura B Eisenmenger Sterling C Johnson Jill N Barnes Source Type: research
