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Total 1739 results found since Jan 2013.
Age at Natural Menopause Impacts Cerebrovascular Reactivity and Brain Structure
Am J Physiol Regul Integr Comp Physiol. 2023 Jan 9. doi: 10.1152/ajpregu.00228.2022. Online ahead of print.ABSTRACTMenopause is associated with adverse changes in vascular health coinciding with an increased risk of stroke and vascular cognitive impairment. However, there is significant variation in the age at menopause. The present study examined how the age at natural menopause impacts cerebrovascular reactivity and structural biomarkers of brain aging. Thirty-five healthy postmenopausal women were classified as early onset menopause (Early; n = 19, age at menopause: 47 ± 2 years) or later onset menopause (Late; n = 16,...
Source: American Journal of Physiology. Regulatory, Integrative and Comparative Physiology - January 9, 2023 Category: Physiology Authors: M Erin Moir Adam T Corkery Katherine A Senese Kathleen B Miller Andrew G Pearson Nicole A Loggie Anna J Howery Sarean H A Gaynor-Metzinger Karly A Cody Laura B Eisenmenger Sterling C Johnson Jill N Barnes Source Type: research
Iron Chelation Therapy to Prevent Post-Stroke Cognitive Impairments: Role of Diabetes and Sex
Am J Physiol Heart Circ Physiol. 2023 Jan 6. doi: 10.1152/ajpheart.00004.2023. Online ahead of print.NO ABSTRACTPMID:36607799 | DOI:10.1152/ajpheart.00004.2023
Source: American Journal of Physiology. Heart and Circulatory Physiology - January 6, 2023 Category: Physiology Authors: Siva S V P Sakamuri Venkata N Sure Prasad V G Katakam Source Type: research
Menstrual phase influences cerebrovascular responsiveness in females but may not affect sex differences
Conclusion: Females during O and ML phases have an enhanced vasoconstrictive capacity of the MCA compared to the EF phase. Additionally, biological sex differences can influence cerebrovascular-CO2 responsiveness, dependent on the insonated vessel.
Source: Frontiers in Physiology - January 4, 2023 Category: Physiology Source Type: research
Deferoxamine Prevents Post-Stroke Memory Impairment in Female Diabetic Rats: Potential Links to Hemorrhagic Transformation and Ferroptosis
Am J Physiol Heart Circ Physiol. 2022 Dec 23. doi: 10.1152/ajpheart.00490.2022. Online ahead of print.ABSTRACTDiabetes increases the risk of post-stroke cognitive impairment (PSCI). Greater hemorrhagic transformation (HT) after stroke is associated with vasoregression and cognitive decline in male diabetic rats. Iron chelator deferoxamine (DFX) prevents vasoregression and improves outcomes. While diabetic female rats develop greater HT, its impact on post-stroke cerebrovascularization and cognitive outcomes remained unknown. We hypothesized that diabetes mediates pathological neovascularization, and DFX attenuates post-str...
Source: American Journal of Physiology. Heart and Circulatory Physiology - December 23, 2022 Category: Physiology Authors: Weiguo Li Yasir Abdul Raghavendar Chandran Sarah Jamil Rebecca A Ward Mohammed Abdelsaid Guangkuo Dong Susan C Fagan Adviye Ergul Source Type: research
