Filtered By:
Condition: Osteoporosis

This page shows you your search results in order of date. This is page number 8.

Order by Relevance | Date

Total 356 results found since Jan 2013.

Relationship between bone strength index of the hemiparetic tibial diaphysis and muscle strength in people with chronic stroke: influence of muscle contraction type and speed
ConclusionsConcentric muscle power was more predictive of %SSD in p-SSI at the tibial diaphysis than other contraction types and may be an important target for intervention to promote bone health in people with chronic stroke.
Source: Osteoporosis International - November 7, 2020 Category: Orthopaedics Source Type: research

Regulatory role of microRNAs on PTEN signaling.
Abstract Phosphatase and tensin homolog (PTEN) gene encodes a tumor suppressor protein which is altered in several malignancies. This protein is a negative regulator of the PI3K/AKT signaling. Several transcription factors regulate the expression of PTEN in positive or negative directions. Moreover, numerous microRNAs (miRNAs) have functional interactions with PTEN and inhibit its expression. Suppression of PTEN can attenuate the response of cancer cells to chemotherapeutic agents. Based on the critical role of this tumor suppressor gene, the identification of negative regulators of its expression has practical si...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - November 7, 2020 Category: Drugs & Pharmacology Authors: Ghafouri-Fard S, Abak A, Shoorei H, Mohaqiq M, Majidpoor J, Sayad A, Taheri M Tags: Biomed Pharmacother Source Type: research

Characteristic of Clinical Studies on Baduanjin during 2000-2019: A Comprehensive Review.
Authors: Zhou J, Yu Y, Cao B, Li X, Wu M, Wen T, Xiong Y, Jia J, Zhao Y Abstract To date, a growing number of clinical studies have demonstrated the safety and health benefits from Baduanjin intervention. Based on this, our objective is to systematically retrieve and summarize the clinical studies on Baduanjin, with a view to providing more evidence-based evidence in support of the application of Baduanjin for healthcare, and to identify the shortcomings of existing research and provide feasibility suggest for further clinical research. Both four English language and four Chinese language electronic databases were ...
Source: Evidence-based Complementary and Alternative Medicine - November 6, 2020 Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research

Risk of Incident Atrial Fibrillation With Zoledronic Acid Versus Denosumab: A Propensity Score –Matched Cohort Study
ABSTRACTZoledronic acid (ZA) is an effective agent in osteoporosis and malignancy ‐related bone disease but may be associated with increased risk of atrial fibrillation (AF), although current studies disagree on this risk. To examine the risk of incident AF among patients receiving ZA compared with denosumab in the first year of treatment, we performed a new‐user, active comp arator cohort study including privately insured Americans between January 1, 2010, and June 30, 2019. Individuals aged ≥50 years without known arrhythmia or advanced kidney disease who initiated ZA were 1:1 propensity score (PS)‐matched to i...
Source: Journal of Bone and Mineral Research - November 2, 2020 Category: Orthopaedics Authors: Kristin M D'Silva, Sara Jane Cromer, Elaine W Yu, Michael Fischer, Seoyoung C Kim Tags: Original Article Source Type: research

Impact of diabetes in patients with COPD
Conclusion: According to our study, in the COPD population, diabetes seems to be associated with more comorbidities and a worse respiratory function while it does not increase exacerbations rate.
Source: European Respiratory Journal - October 28, 2020 Category: Respiratory Medicine Authors: Slim, A., Kamoun, H., Saidane, A., Hdidene, Y., Ben Abdelghaffar, H., Smadhi, H., Greb, D., Akrout, I., Hassene, H., Fekih, L., Megdiche, M. L. Tags: Clinical problems Source Type: research

When the Nervous System Turns Skeletal Muscles into Bones: How to Solve the Conundrum of Neurogenic Heterotopic Ossification
AbstractPurpose of ReviewNeurogenic heterotopic ossification (NHO) is the abnormal formation of extra-skeletal bones in periarticular muscles after damage to the central nervous system (CNS) such as spinal cord injury (SCI), traumatic brain injury (TBI), stroke, or cerebral anoxia. The purpose of this review is to summarize recent developments in the understanding of NHO pathophysiology and pathogenesis. Recent animal models of NHO and recent findings investigating the communication between CNS injury, tissue inflammation, and upcoming NHO therapeutics are discussed.Recent FindingsAnimal models of NHO following TBI or SCI ...
Source: Current Osteoporosis Reports - October 21, 2020 Category: Orthopaedics Source Type: research

Epidemiological characteristics and related factors of frailty in older Chinese adults with hypertension: a population-based study
Conclusion: The current study provides the first evidence regarding the status of frailty in older Chinese adults with hypertension.
Source: Journal of Hypertension - October 9, 2020 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology and risk factors Source Type: research

Relationship between bone disorders and stroke
AbstractBone disorders are among the most uncommon causes of stroke, but they should be considered as stroke cause in particular clinical scenarios. On the other hand, osteoporosis/osteopenia and increased fracture risk are well documented post stroke complications. The relationship between stroke and bone health is complex. The current facts suggest that these two conditions share same risk factors, but also are risk factors for each other. However, the evidence shows more clear effect of stroke on the bone health, than in the opposite direction. This extensive review is aiming to fill the huge gap of evidence about this ...
Source: Neurological Sciences - October 1, 2020 Category: Neurology Source Type: research

Romosozumab: A Novel Injectable Sclerostin Inhibitor With Anabolic and Antiresorptive Effects for Osteoporosis.
CONCLUSIONS: Romosozumab offers an alternative for patients with a high risk of osteoporotic fractures. Clinicians should avoid romosozumab in patients with a history of myocardial infarction or stroke in the past 12 months. PMID: 32862655 [PubMed - as supplied by publisher]
Source: The Annals of Pharmacotherapy - August 28, 2020 Category: Drugs & Pharmacology Authors: Nealy KL, Harris KB Tags: Ann Pharmacother Source Type: research

Evaluation of the Effectiveness of Treatment with Botulinum Toxin on Sleep Quality in Stroke-Related Spasticity
Stroke is one of the most common causes of mortality and neurological disability worldwide.1 Spasticity is one of the most common findings of hemiplegia after stroke and the rate of spasticity after stroke is 40%.2 Spasticity is defined as sensory-motor control disorder, arising from intermittent or continuous involuntary activation of muscles resulting from upper motor neuron lesion.3 Although spasticity has benefits such as contributing to standing and walking, preventing osteoporosis, deep vein thrombosis and contributing to blood circulation, it is a complex disorder that causes serious disability in daily life activit...
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Hulya Deveci Source Type: research

Risk Factors for the Recurrence of Benign Paroxysmal Positional Vertigo: A Systematic Review and Meta-Analysis.
CONCLUSION: These findings strengthen clinical awareness of early warning to identify patients with potential relapse risk of BPPV and clinicians should counsel patients regarding the importance of follow-up after diagnosis of BPPV. PMID: 32776833 [PubMed - as supplied by publisher]
Source: Ear, Nose and Throat Journal - August 9, 2020 Category: ENT & OMF Authors: Li S, Wang Z, Liu Y, Cao J, Zheng H, Jing Y, Han L, Ma X, Xia R, Yu L Tags: Ear Nose Throat J Source Type: research

Clinical research linking Traditional Chinese Medicine constitution types with diseases: a literature review of 1639 observational studies.
CONCLUSION: Eight biased TCM constitutions were closely related to specific diseases, and could be used to guide individualized prevention and treatment. More rigorously designed studies are recommended to further verify the constitution-disease relationship. PMID: 32744037 [PubMed - in process]
Source: Journal of Traditional Chinese Medicine - July 31, 2020 Category: Complementary Medicine Authors: Liang X, Wang Q, Jiang Z, Li Z, Zhang M, Yang P, Wang X, Wang Y, Qin Y, Li T, Zhang T, Wang Y, Sun J, Li Y, Luo H, Li L Tags: J Tradit Chin Med Source Type: research

Factors associated with fracture after stroke and TIA: a long-term follow-up
ConclusionStroke was positively associated with fracture in patients<  80 years, while TIA was positively associated with fracture in patients ≥ 80 years and females. Dementia and analgesic therapy were also associated with fracture after either stroke or TIA.
Source: Osteoporosis International - July 9, 2020 Category: Orthopaedics Source Type: research

Is there a role for menopausal hormone therapy in the management of postmenopausal osteoporosis?
We present a narrative review of the benefits versus risks of using MHT in the management of postmenopausal osteoporosis. Current literature suggests robust anti-fracture efficacy of MHT in patients unselected for low BMD, regardless of concomitant use with progestogens, but with limited evidence of persisting skeletal benefits following cessation of therapy. Side effects include cardiovascular events, thromboembolic disease, stroke and breast cancer, but the benefit-risk profile differs according to the use of opposed versus unopposed oestrogens, type of oestrogen/progestogen, dose and route of delivery and, for cardiovas...
Source: Osteoporosis International - July 7, 2020 Category: Orthopaedics Source Type: research