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Condition: Osteoporosis

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Total 356 results found since Jan 2013.

Saving bones without risking brain —bisphosphonates and risk of stroke: matched case-control study
ConclusionsWe found no association between bisphosphonate treatment and risk of stroke, after adjusting for other confounders.
Source: Osteoporosis International - June 16, 2019 Category: Orthopaedics Source Type: research

The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea.
CONCLUSION: The CIFs of fractures are about 8% at 2 years and 13% at 4 years after acute ischemic stroke in Korea. Older age, women, pre-stroke fracture and osteoporosis raised the risk of post-stroke fractures. PMID: 31172697 [PubMed - in process]
Source: Journal of Korean Medical Science - June 8, 2019 Category: Biomedical Science Tags: J Korean Med Sci Source Type: research

The Design and Validation of a New Algorithm to Identify Incident Fractures in Administrative Claims Data
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - June 5, 2019 Category: Orthopaedics Authors: Nicole C. Wright, Shanette G. Daigle, Mary E. Melton, Elizabeth S. Delzell, Akhila Balasubramanian, Jeffrey R. Curtis Tags: ORIGINAL ARTICLE Source Type: research

The Endocannabinoid System and its Modulation by Cannabidiol (CBD).
Abstract The endocannabinoid system (ECS) is an extensive endogenous signaling system with multiple elements, the number of which may be increasing as scientists continue to elucidate its role in human health and disease. The ECS is seemingly ubiquitous in animal species and is modulated by diet, sleep, exercise, stress, and a multitude of other factors, including exposure to phytocannabinoids, like Cannabidiol (CBD). Modulating the activity of this system may offer tremendous therapeutic promise for a diverse scope of diseases, ranging from mental health disorders, neurological and movement disorders, pain, autoi...
Source: Alternative Therapies in Health and Medicine - May 31, 2019 Category: Complementary Medicine Authors: Corroon J, Felice JF Tags: Altern Ther Health Med Source Type: research

Prevent Osteoporotic Fractures With a Fracture Liaison Service
Imagine leaving the hospital after suffering a heart attack without being treated for hypertension or being started on a beta blocker. What would we think of the hospital where patients are never educated about the relationship between treating hypertension and reducing myocardial infarction and stroke risk? Unfortunately, this happens every day with osteoporosis and fractures... [Read More]
Source: The Rheumatologist - May 18, 2019 Category: Rheumatology Authors: Micah Yu, MD, Anna Lafian, DO, & Christina Downey, MD Tags: Conditions Osteoporosis osteoporotic fracture rates Source Type: research

Stroke survivors have four times osteoporosis risk of healthy people
Even though a stroke is the main risk factor for osteoporosis, most survivors don't receive screenings or treatment for the dangerous bone condition.
Source: Health News - UPI.com - April 25, 2019 Category: Consumer Health News Source Type: news

Stroke Patients Infrequently Screened, Treated for Bone Loss
THURSDAY, April 25, 2019 -- Patients with recent stroke are rarely screened and treated for osteoporosis, according to a study published online April 25 in Stroke. Noting that stroke is a risk factor for subsequent osteoporosis and fractures, Eshita...
Source: Drugs.com - Pharma News - April 25, 2019 Category: Pharmaceuticals Source Type: news

After a Stroke, Your Bones Need Care
THURSDAY, April 25, 2019 -- Stroke survivors often face limited mobility, which quadruples their odds of osteoporosis, broken bones and falls. But most are never screened for these problems, new research reveals. " Our study adds to previous...
Source: Drugs.com - Daily MedNews - April 25, 2019 Category: General Medicine Source Type: news

Osteoporosis and Sarcopenia Increase Frailty Syndrome in the Elderly
Conclusions World population is aging and the increase in life expectancy is often unhealthy. In particular, musculoskeletal aging, which leads to sarcopenia and osteoporosis, has several causes such as changes in body composition, inflammation, and hormonal imbalance. Sarcopenia, osteoporosis, and more frequently, sarcopenic obesity are commonly associated with aging and frequently closely linked each other, often leading to the development of a frailty syndrome. Frailty syndrome favors an increased risk of loss function in daily activities, for cardiovascular diseases, cancers, falls, and mortality. As the number of eld...
Source: Frontiers in Endocrinology - April 23, 2019 Category: Endocrinology Source Type: research

Exercise as a Prescription for Patients with Various Diseases
Publication date: Available online 18 April 2019Source: Journal of Sport and Health ScienceAuthor(s): Xin Luan, Xiangyang Tian, Haixin Zhang, Rui Huang, Na Li, Peijie Chen, Ru WangAbstractA growing understanding of the benefits of exercise over the past few decades has prompted researchers to take an interest in the possibilities of exercise therapy. Because each sport has its own set of characteristics and physiological complications that tend to appear during exercise training, the effects and underlying mechanisms of exercise remain unclear. Thus, the first step in probing exercise effects on different diseases is the s...
Source: Journal of Sport and Health Science - April 20, 2019 Category: Sports Medicine Source Type: research

817 Ethanol induces skin hyperpigmentation in mice with aldehyde dehydrogenase 2 deficiency
Excessive alcohol consumption leads to alcohol use disorder. Alcohol is metabolized to acetaldehyde, which is then oxidized to acetic acid by aldehyde dehydrogenases (ALDH), a class of enzymes that facilitate the conversion of aldehydes to their corresponding acids. Among ALDHs, mitochondrial ALDH2 is the primary enzyme involved in the metabolism of acetaldehyde. In addition to its well-known role in ethanol metabolism, recent studies have suggested that ALDH2 dysfunction is associated with a variety of human diseases including cardiovascular diseases, diabetes, neurodegenerative diseases, stroke, cancer, anemia, pain, osteoporosis and aging.
Source: Journal of Investigative Dermatology - April 19, 2019 Category: Dermatology Authors: T. Yamauchi, A. Matsumoto, S. Ito, K. Wakamatsu, T. Suzuki, M. Fujita Tags: Pigmentation and Melanoma Source Type: research

Geniposide Alleviates Glucocorticoid-Induced Inhibition of Osteogenic Differentiation in MC3T3-E1 Cells by ERK Pathway
Conclusion In summary, we demonstrated that geniposide alleviated GC-induced osteogenic suppression in MC3T3-E1 cells. The effects of geniposide were at least partially associated with activating ERK signaling pathway via GLP-1 receptor. Geniposide might be a potential therapeutic agent for protection against GC-induced osteoporosis. Author Contributions BX, DX, CZ, and LW participated in research design. BX, JW, YL, XW, and ZZ conducted the experiments. BX, DX, and LW contributed new reagents or analytic tools and wrote or contributed to the writing of the manuscript. BX, JW, CZ, and DX performed the data analysis. Fu...
Source: Frontiers in Pharmacology - April 17, 2019 Category: Drugs & Pharmacology Source Type: research

Plant-Derived Alkaloids: The Promising Disease-Modifying Agents for Inflammatory Bowel Disease
Conclusion This paper summarizes the current findings regarding the anti-colitis activity of plant-derived alkaloids and shows how these alkaloids exhibit significant and beneficial effects in alleviating colonic inflammation. These natural alkaloids are not only promising agents for IBD treatment but are also components for developing new wonder drugs. However, the underlying molecular mechanisms or toxicological evaluation of most plant-derived alkaloids still require much scientific research, and their actual efficacies for IBD patients have not been verified well in field research. Thus, further clinical trials to elu...
Source: Frontiers in Pharmacology - April 11, 2019 Category: Drugs & Pharmacology Source Type: research