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No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Intensive blood pressure-lowering strategy should also be offered to older patients
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Reply
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Gestational blood pressure by 2017 American College of Cardiology/American Heart Association guideline and hypertension associated risks for mothers and newborns
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Evaluating sources of bias in observational studies of angiotensin-converting enzyme inhibitor/angiotensin II receptor blocker use during COVID-19: beyond confounding
Concerns over ACE inhibitor or ARB use to treat hypertension during COVID-19 remain unresolved. Although studies using more robust methodologies provided some clarity, sources of bias persist and it remains critical to quickly address this question. In this review, we discuss pernicious sources of bias using a causal model framework, including time-varying confounder, collider, information, and time-dependent bias, in the context of recently published studies. We discuss causal inference methodologies that can address these issues, including causal diagrams, time-to-event analyses, sensitivity analyses, and marginal struct...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: COVID-19 Source Type: research

Renin–angiotensin-system inhibitors and all-cause mortality in patients with COVID-19: a systematic review and meta-analysis of observational studies
Conclusion: In patients with COVID-19, we found no association between ACEI/ARB treatment and mortality/severe disease. ACEI/ARB should not be discontinued, unless clinically indicated. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: COVID-19 Source Type: research

Regression of left ventricular hypertrophy in primary aldosteronism after adrenalectomy: a meta-analysis of echocardiographic studies
Aim: Available evidence on regression of left ventricular (LV) hypertrophy in patients with primary aldosteronism after unilateral adrenalectomy is scanty. We performed a systematic meta-analysis of echocardiographic studies to provide an updated and comprehensive information on this issue. Methods: The PubMed, OVID-MEDLINE and Cochrane library databases were analyzed to search English-language articles published from 1 January 1990 up to 30 June 2020. Studies were identified by using MeSH terms and crossing the following search items: ‘primary aldosteronism’ ‘Conn's syndrome’ ‘adre...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Renal outcomes and blood pressure patterns in diabetic and nondiabetic individuals at high cardiovascular risk
Conclusion: In patients at high cardiovascular risk, SBP levels more than 140 mmHg and less than 120 are associated with increased risk for renal outcomes. Renal risk was greater in diabetes across the whole range of achieved SBP and DBP. These data suggest similar target BP range in patients with and without diabetes to prevent renal outcomes, a frequent complication in high-risk vascular patients. Clinical trial registration: Clinical Trial registration: http://clinicaltrials.gov.Unique identifier: NCT00153101. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Radiofrequency ablation for adenoma in patients with primary aldosteronism and hypertension: ADERADHTA, a pilot study
Conclusion: Radiofrequency ablation for hypertensive patients with aldosterone-producing adenomas seems to be an emerging promising alternative to surgery. Its efficacy and its feasibility have to be confirmed in a larger sample of patients. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Dapagliflozin decreases ambulatory central blood pressure and pulse wave velocity in patients with type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial
Objectives: Sodium-glucose co-transporter 2 (SGLT-2) inhibitors reduce the incidence of heart failure and death in patients with type-2 diabetes mellitus. Arterial stiffness is a prominent risk factor for heart failure and overall mortality. The aim of this study was to evaluate the effects of dapagliflozin on ambulatory brachial and central blood pressure (BP) levels and arterial stiffness parameters in patients with type-2 diabetes mellitus. Methods: This is a double-blind, randomized, placebo-controlled clinical trial including 85 adult patients with type-2 diabetes mellitus on monotherapy or combination ther...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Trends in hypertension prevalence, awareness, treatment and control rates among Chinese adults, 1991–2015
We examined recent trends in the prevalence, awareness, treatment and control of hypertension among Chinese adults from 1991 to 2015 based on the 2018 Chinese Guideline. Methods: A total of 72 452 adults aged 20–79 years from the China Health and Nutrition Survey conducted between 1991 and 2015 were included in the study. Hypertension status and control rate were defined according to the 2018 Chinese Guideline. Age-standardized estimates were calculated based on the age distribution of the WHO standard population. Results: From 1991 to 2015, the crude/age-standardized hypertension prevalence (14.0/15....
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Effects of a Mediterranean diet on blood pressure: a systematic review and meta-analysis of randomized controlled trials and observational studies
Objective: To conduct a systematic review and meta-analysis investigating effects of MedDiet on blood pressure in randomized controlled trials (RCTs) and associations of MedDiet with risk of hypertension in observational studies. Methods: PubMed, The Cochrane Library and EBSCOhost were searched from inception until January 2020 for studies that met the following criteria: participants aged at least 18 years, RCTs investigating effects of a MedDiet versus control on BP, observational studies exploring associations between MedDiet adherence and risk of hypertension. Random-effects meta-analyses were conducted. Met...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Relations of aortic stiffness with arterial damage beyond brachial pressure are both dependent and independent of central arterial pulsatile load
Aim: We aimed to determine whether the impact of aortic stiffness on atherosclerotic or small vessel end organ damage beyond brachial blood pressure depends in-part on stiffness-induced increases in central arterial pressures produced by an enhanced resistance to flow (characteristic impedance, Zc). Methods: We studied 1021 participants, 287 with stroke or critical limb ischaemia, and 734 from a community sample with atherosclerotic or small vessel end organ measures. Central arterial haemodynamics were determined from arterial pressure (SphygmoCor) and velocity and diameter assessments in the outflow tract (ech...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Early ventricular contraction in children with primary hypertension relates to left ventricular mass
Aims: In hypertensive adults, first-phase ejection fraction (EF1), a measure of early ventricular contraction is reduced and associated with prolonged systolic contraction and diastolic dysfunction. Whether this is true in children with primary hypertension is unknown. Methods: Echocardiography was performed in 47 normotensive and 81 hypertensive children. Hypertensive children were stratified according to tertiles of LVMi (g/m2.7). EF1 was calculated from the fraction of LV volume ejected up to the time of peak aortic flow. E/e’ was used as a measure of diastolic function. Myocardial wall stress (MWS) was...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Arterial hypertension and morphologic abnormalities of cardiac chambers: results from the Copenhagen General Population Study
Objectives: In patients with arterial hypertension (AH), hypertension-mediated organ damage may be manifested by cardiac chamber enlargement and/or remodeling. Cardiac computed tomography imaging has emerged as an important method for morphological assessment of cardiac chambers. We tested the hypothesis that prevalence of cardiac chamber abnormalities is specifically related to clinical categories of AH in the general population. Methods: We studied 4747 individuals, mean age was 60 years (range: 40–93), 46% were men, undergoing 320-detector computed tomography in the Copenhagen General Population Study. ...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Estimated pulse wave velocity is associated with residual-specific mortality: findings from the National Health and Nutrition Examination Survey
Conclusion: ePWV is associated with residual-specific mortality in a nationally representative sample of adults. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Leptin levels predict the development of left ventricular hypertrophy in a sample of adult men: the Olivetti Heart Study
Objective: A higher leptin (LPT) is associated with a greater cardiometabolic risk. Some studies also showed a positive association between LPT and cardiovascular organ damage but no consistent data are available about a predictive role of LPT on cardiac remodelling. Hence, the aim of this study was to evaluate the potential role of LPT on the incidence of left ventricular hypertrophy (LVH) in a sample of adult men. Methods: The study population was made up of 439 individuals (age: 51 years) without LVH at baseline, participating in The Olivetti Heart Study. The ECG criteria were adopted to exclude LVH at baseli...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Longitudinal sleep characteristics and hypertension status: results from the Wisconsin Sleep Cohort Study
Aims: Sleep characteristics such as short sleep duration or sleep-disordered breathing are established predictors of hypertension. However, few studies have used in-lab polysomnography with a longitudinal design to measure how hypertension is associated with different sleep stages over time. The purpose of this study is to examine whether hypertension is associated with the longitudinal course of sleep quality over time. Methods: The current study evaluated data from the Wisconsin Sleep Cohort Study, which consists of 1525 adults in a community-based population of middle-aged to older adults followed for approxi...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Other risk factors Source Type: research

Relationship between casual serum triglyceride levels and the development of hypertension in Japanese
Conclusion: Serum triglyceride levels were significantly associated with development of hypertension in a Japanese worksite population. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Other risk factors Source Type: research

Associations of household solid fuel for heating and cooking with hypertension in Chinese adults
Conclusion: The current large Chinese study revealed a statistically insignificant increase in the association between solid fuel use for heating and hypertension prevalence or BP. As this cross-sectional study has its inherent limitation on causality, findings from this study would have to be confirmed by prospective cohort studies. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Other risk factors Source Type: research

The association between indices of blood pressure waveforms (PTC1 and PTC2) and incident heart failure
Conclusion: The PTC2 measure of the radial artery pulse waveform may represent a novel phenotype related to heart failure, especially heart failure with reduced ejection fraction. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure epidemiology Source Type: research

Social connections and hypertension in women and men: a population-based cross-sectional study of the Canadian Longitudinal Study on Aging
Conclusion: Social ties appear to be more strongly associated with hypertension in middle and older aged women than men. Women who are nonpartnered or who engage in few social activities and men who are coliving represent at risk groups for having hypertension. Healthcare professionals may need to consider these social factors in addressing risk for hypertension and cardiovascular disease prevention. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure epidemiology Source Type: research

Association of occupational noise exposure, bilateral hearing loss with hypertension among Chinese workers
Objective: To evaluate the relationship of occupational noise, bilateral hearing loss with blood pressure and hypertension among a Chinese population. Methods: We included 15 422 individuals from a cross-sectional survey of the key occupational diseases in 2017 in Wuhan, Hubei Province, China. Occupational noise exposure was evaluated through workplace noise level and/or the job titles. Hearing loss was defined as a pure-tone average of 25 dB or higher at speech frequency (0.5, 1, 2 kHz) or high frequency (3, 4, 6 kHz) in both ears. Hypertension was defined as blood pressure at least 140/90 mmHg or sel...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure epidemiology Source Type: research

Associations of biogeographic ancestry with hypertension traits
Conclusion: These results demonstrate that risk for BP traits varies significantly by genetic ancestry. Our findings provide insight into the geographic origin of genetic factors underlying hypertension risk and establish that a portion of BP trait ethnic disparities are because of genetic differences between ancestries. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure epidemiology Source Type: research

Familial tendency for hypertension is associated with increased vascular stiffness
Objective: Hypertension is the leading cause of cardiovascular disease and premature death. New methods for early detection of hypertension and its consequences can reduce complications arising from uncontrolled hypertension. Pulse-wave velocity (PWV), a measure of arterial stiffness, has been recognized as a valuable tool in assessing risk for cardiovascular complications, although its use in clinical practice is currently limited. Here we examine whether brachial--ankle PWV (baPWV) and femoral--ankle PWV (faPWV) are elevated in nonhypertensive volunteers, with and without a history of familial hypertension. Method...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure epidemiology Source Type: research

Visit-to-visit variability in blood pressure among cannabis users participating in the Third National Health and Nutrition Examination Survey
Conclusion: Active cannabis use is associated with BPV. Future research is needed to understand the effects of cannabis use on BP regulation. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure measurement Source Type: research

Automated blood pressure measurement in atrial fibrillation: validation process modification and evaluation of a novel professional device which detects atrial fibrillation and adapts its blood pressure measurement algorithm
This study evaluated the accuracy of a novel professional oscillometric upper-arm cuff device (Microlife WatchBP Office), which has an algorithm for detecting AF and then applies an AF-specific BP measurement algorithm. BP variability, which is inherently increased in AF patients, was considered in the analysis. Methods: Subjects with sustained AF were included in a validation study using the same arm sequential measurement method of the Universal Standard (ISO 81060-2:2018) for special populations. Analysis was performed in all subjects and separately in those with and without high reference BP variability (>12/...
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure measurement Source Type: research

Invasive aortic pulse pressure is not superior to cuff pulse pressure in cardiovascular risk prediction
Conclusion: Invasively measured aortic PP did not add prognostic information about cardiovascular outcomes and death beyond cuff PP in patients with stable angina pectoris. (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure measurement Source Type: research

Evaluating sources of bias in observational studies
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

Cardiac computed tomography for left ventricular remodeling assessment: does it mean echocardiography moves for the past?
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

Hypertension and sleep health: a multidimensional puzzle
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

Highlights of the April issue
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - March 11, 2021 Category: Cardiology Tags: EDITOR'S CORNER Source Type: research

Growth differentiation factor 15 levels are similar in primary aldosteronism and essential hypertension and do not predict arterial inflammation
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Reply
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Blood pressure and outcome in patients with atrial fibrillation: floating in uncharted waters
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Resistant or refractory hypertension: it is not just the of number of drugs
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: EDITORIAL Source Type: research

Congenital defects and early childhood outcomes following in-utero exposure to antihypertensive medication
Conclusion: Although circulatory defects may be associated with antihypertensive medication exposure during pregnancy, the mechanisms underlying this process are unclear. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Pregnancy Source Type: research

Circulating angiogenic factors are associated with progression to preeclampsia and the occurrence of adverse outcomes in women with gestational hypertension
Objective: Gestational hypertension is characterized by an imbalance in angiogenic factors. The goal of the current study was to evaluate whether circulating concentrations of proangiogenic and antiangiogenic factors are associated with the risk of progression to preeclampsia and development of adverse outcomes in women with gestational hypertension. Methods: We studied 496 women with gestational hypertension. Patients were divided into three groups based on their degree of angiogenic imbalance, evaluated by the soluble fms-like tyrosine kinase-1/placental growth factor ratio: no angiogenic imbalance (≤38), m...
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Pregnancy Source Type: research

Secondary hyperparathyroidism is associated with postpartum blood pressure in preeclamptic women and normal pregnancies
In this study, we examine the relationships of calcium metabolism with blood pressure (BP) in preeclamptic women and in a control group of normal (NORM) pregnancies in the postpartum. Methods: Sixty-three consecutive preeclamptic women (age 35 ± 6 years) were studied 4 weeks after delivery. We collected clinical and lab information on pregnancy and neonates and measured plasma and urinary calcium and phosphate, plasma parathyroid hormone (PTH) and 25-hydroxy vitamin D [25(OH)D], and performed 24-h ambulatory BP monitoring. BP and calcium metabolism of 51 preeclamptic were compared with 17 NORM pregnant wo...
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Pregnancy Source Type: research

Endovascular reversal of renovascular hypertension blunts cardiac dysfunction and deformation in swine
Conclusion: In addition to cardiac LV adaptive hypertrophy and diastolic dysfunction, short-term RVH causes cardiac deformation. Despite only partial improvement in BP, PTRA effectively restored cardiac function and reversed abnormal mechanics. Hence, renal revascularization may be a useful strategy to preserve cardiac function in RVH. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research

Complementary value of ECG and echocardiographic left ventricular hypertrophy for prediction of adverse outcomes in the general population
Conclusion: Our study provides strong evidence that ECG-LVH is associated with adverse outcomes, independent of Echo-LVH. Clinically, ECG-LVH could be considered as a consequential factor, especially in those with Echo-LVH. These findings have potential clinical relevance for risk stratification. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research

Additive effect of hypertension on left ventricular structure and function in patients with asymptomatic type 2 diabetes mellitus
Conclusion: Hypertension in the context of diabetes is significantly associated with LV diastolic function and concentric remodeling; however, it has little effect on systolic function, myocardial microcirculation, or fibrosis independent of covariates, which provide clinical evidence for understanding the pathogenesis of comorbidities and explaining the development of distinct heart failure phenotypes. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research

Contribution of systemic blood flow to untreated or inadequately controlled systolic--diastolic or isolated systolic hypertension in a community sample of African ancestry
Aims: Age-related increases in systemic blood flow [stroke volume (SV), cardiac output (CO), and aortic flow (Q)] contribute substantially to untreated or inadequately controlled (uncontrolled) blood pressure (BP) in Africa. We aimed to identify the haemodynamic determinants of uncontrolled systolic--diastolic (Syst--diast HT) versus uncontrolled isolated systolic (ISH) or diastolic (IDH) hypertension. Methods: Using central arterial pressure and aortic outflow tract velocity and diameter measurements (echocardiography), the haemodynamic correlates of BP were determined in 725 community participants of African a...
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Heart Source Type: research

Isolated diastolic hypertension as defined by the 2017 American College of Cardiology/American Heart Association blood pressure guideline and incident cardiovascular events in Chinese
Conclusion: In this adult Chinese community, 2017 ACC/AHA-defined IDH was associated with the incidence of cerebral hemorrhage and total CVD, and as compared with JNC7-defined IDH, it was more prevalent. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research

Association of small dense LDL-cholesterol with disease severity, hypertension status and clinical outcome in patients with coronary artery disease
Objective: Previous studies have demonstrated that small dense LDL-cholesterol (sdLDL-C) is related to the pathogenesis of coronary artery disease (CAD). However, its prognostic role in hypertensive patients with CAD has been undetermined. The aim of the study was to investigate the association between sdLDL-C with disease severity, hypertensive status and clinical outcome in patients with CAD. Methods: A total of 4594 patients with angiography-proven CAD were consecutively enrolled and categorized into subgroups according to blood pressure status. Serum sdLDL-C levels were measured by direct quantitative measur...
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research

Long-term risk of stroke and myocardial infarction in middle-aged men with a hypertensive response to exercise: a 44-year follow-up study
Conclusion: Among middle-aged men with high resting and maximum blood pressure during maximum exercise workload, an increased risk of stroke was observed but not for MI. Further studies with larger sample sizes are needed to investigate the underlying mechanisms of the increased risk of stroke among individuals with hypertensive response to exercise. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research

Exercise SBP response and incident depressive symptoms: The Maastricht Study
Conclusion : A higher exercise SBP response is associated with a higher incidence of clinically relevant depressive symptoms. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research

Associations of estimated 24-h urinary sodium excretion with mortality and cardiovascular events in Chinese adults: a prospective cohort study
Objective: To investigate the associations of sodium excretion with blood pressure, mortality and cardiovascular diseases in Chinese population. Methods: We studied 39 366 individuals aged 35–70 years from 115 urban and rural communities in 12 centers across mainland China. Trained research staff conducted face-to-face interview to record baseline information of all participants based on questionnaires, and collected their morning fasting urine samples to estimate 24-h sodium excretion (24hUNaE). Multivariable frailty Cox regression accounting for clustering by centre was performed to examine the associa...
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research

Association of age at menarche with hypertension in rural Chinese women
Conclusion: Early age at menarche was positively associated with hypertension. Adiposity and insulin resistance seemed to be two vital mediators of the association between age at menarche and hypertension in rural Chinese women. (Source: Journal of Hypertension)
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research

Hyperglycemia and arterial stiffness across two generations
Objective: Hyperglycemia and diabetes mellitus associate with arterial stiffness. This observational study aimed to investigate such links in two related generations from a population-based study. Methods: Data from 2640 participants in the ongoing Malmö Offspring Study, Sweden, was used. The participants were direct descendants, that is, parents (median age 52.5 years) and children (26.9 years). In linear regressions, arterial stiffness measured through carotid--femoral pulse wave velocity was associated with markers of glucose metabolism (fasting glucose, glycated hemoglobin, skin autoflourescence of Adva...
Source: Journal of Hypertension - February 12, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiology of hypertension and associated risk factors Source Type: research