In Memoriam: professor Antonio Salvetti (1936–2021)
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: OBITUARY Source Type: research

Importance of knowledge, perception and practice of health professionals regarding blood pressure measurement methods
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Clothing and blood pressure variability
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

The complex interaction between vitamin D, folate, and heavy metals: potential for attenuation of blood pressure effects
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Reply
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Dietary sodium and cardiovascular disease in China: concerns about the methods, conclusions, and evidence review
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Bilateral detachment of the neurosensory retina in an apparently asymptomatic woman
Systemic hypertension is related to a variety of retinal manifestations. Reported herein is a case of malignant hypertension associated with bilateral foveal neurosensory detachment in a middle age woman with stenosis of the left renal artery. The present case outlines the importance of recognizing ocular manifestations as a possible consequence of life-threatening systemic disease. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: CASE REPORT Source Type: research

Optimal blood pressure levels in different phases of peripheral thrombolysis period in acute ischemic stroke
Conclusions: Maintaining SBP levels (≤148 mmHg) from admission to the first 24 h after thrombolysis, then keeping SBP levels (127–138 mmHg) would be beneficial. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Ambulatory blood pressure changes with lung ultrasound-guided dry-weight reduction in hypertensive hemodialysis patients: 12-month results of a randomized controlled trial
This study examines the long-term effects of dry-weight reduction with a standardized lung-ultrasound (US)-guided strategy on ambulatory BP in hypertensive hemodialysis patients. Methods: This is the report of the 12-month follow-up of a randomized controlled trial in 71 clinically euvolemic, hemodialysis patients with hypertension. Patients were randomized to dry-weight reduction guided by prehemodialysis lung ultrasound and to standard care. A 48-h ambulatory BP monitoring (ABPM) was performed in all study participants at baseline and after 12 months. Results: During follow-up, a greater proportion of pat...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Effectiveness of statin intensive therapy in type 2 diabetes mellitus with high visit-to-visit blood pressure variability
Background: Intensive lipid-lowering therapy is recommended in type 2 diabetes mellitus (T2DM) patients with target organ damage. However, the evidence is insufficient to stratify the patients who will benefit from the intensive therapy among them. High visit-to-visit variability in systolic blood pressure (SBP) is associated with increased risk of cardiovascular events. We investigated the effectiveness of intensive versus standard statin therapy in the primary prevention of cardiovascular events among T2DM patients with retinopathy stratified by visit-to-visit SBP variability. Methods: The standard versus inte...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Limited reliability of heart rate as a sympathetic marker in chronic kidney disease
Background: Chronic kidney disease (CKD) is characterized by a pronounced sympathetic overactivity as documented by the marked increase in muscle sympathetic nerve traffic (MSNA) and in plasma norepinephrine reported in this condition. Whether and to what extent in CKD heart rate (HR) reflects the adrenergic overdrive remains undefined. It is also undefined the relative validity of the different adrenergic markers in reflecting renal dysfunction. Materials and methods: In 82 CKD patients, aged 58.4 ± 1.1 years (mean ± SEM), we measured resting clinic blood pressure, HR (EKG), venous NE (HPL...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Septal curvature as a robust and reproducible marker for basal septal hypertrophy
Conclusion: Average septal curvature is a more precisely defined and reproducible metric than thickness ratios, it can be fully automated, and better infers the functional remodelling related to hypertension. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Impact of cortisol on blood pressure and hypertension-mediated organ damage in hypertensive patients
Conclusion: Cortisol influences weakly the level of BP independently from plasma aldosterone in hypertensive patients, particularly in older patients, and that there was weak association with HMOD. It may, therefore, be of interest to test specific treatments targeting cortisol excess in selected hypertensive patients. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Local transversal aortic strain is impaired in ascending aorta dilatation
Background: Ascending aorta dilatation is found in 13% of hypertensive patients. Little is known about elastic properties of ascending aorta in such patients. Echo-based transverse aortic strain analysis can describe mechanical properties of ascending aorta but has never been applied to patients with ascending aorta dilatation. Aim: To assess mechanical properties of ascending aorta by transverse aortic strain analysis (as β2-stiffness index) in hypertensive patients with ascending aorta dilatation and association between mechanical properties of ascending aorta and cardiovascular damage. Methods: A ...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Meal patterns and incident hypertension in community-dwelling middle-aged adults: an 11-year follow-up cohort study
Conclusion: Dinner dominant meal pattern was associated with a lower risk of hypertension compared with the balanced meal pattern in Chinese adults. A relatively small breakfast and large dinner may help to prevent or delay the development of hypertension, especially in urban residents. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiological aspects Source Type: research

Association between the proportions of carbohydrate and fat intake and hypertension risk: findings from the China Health and Nutrition Survey
Conclusion: An HCLF diet was significantly associated with an increased risk of hypertension. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiological aspects Source Type: research

Association of long-term SBP with clinical outcomes and quality of life in heart failure with preserved ejection fraction: an analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trial
Aims: To determine the associations of long-term SBP (LT-SBP) levels with clinical outcomes and health-related quality of life in heart failure with preserved ejection fraction (HFpEF). Methods and results: We analyzed participants from the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) study with available different SBP measurements from different follow-ups (n = 3310). LT-SBP was the mean SBP value from 4-week measurement to the last one. The outcome measures are all-cause mortality and a composite of heart failure readmission or all-cause mortality and the Ka...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiological aspects Source Type: research

The aortic-femoral arterial stiffness gradient: an atherosclerosis risk in communities (ARIC) study
Conclusion: Although future studies are necessary to confirm clinical utility, the af-SG is a promising tool that may provide a unique picture of hemodynamic integration and identification of CVD risk when compared with cfPWV. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiological aspects Source Type: research

Endothelial function of healthy adults from 20 to 91 years of age: prediction of cardiovascular risk by vasoactive range
This study is the first to provide reference values and to assess the predictive value of L-FMC, FMD and their composite endpoint vasoactive range (VAR) in healthy adults. Methods: L-FMC, FMD and VAR were measured in 457 nonsmoking adults of 20–91 years without chronic diseases, medication, with normal heart function and very low cardiovascular risk. Sex-specific percentiles were calculated and predictive ability for elevated cardiovascular risk was assessed using receiver-operating characteristic (ROC) curves. Results: From 20 to 91 years of age, L-FMC increased 86.1 and 105.3%, FMD decreased 63.6 ...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Epidemiological aspects Source Type: research

Increased pulse wave velocity in patients with an orthostatic blood pressure rise independent of other cardiovascular risk factors
Conclusion: Both an orthostatic BP drop and rise were associated with elevated PWV. Although standing BP is commonly measured in elderly hypertensive patients to exclude significant orthostatic hypotension, this simple measurement may provide an additional independent risk factor for vascular HMOD at any age. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure measurement Source Type: research

Within-visit and between-visit intra-individual blood pressure variability in an unselected adult population from rural China
Conclusion: In a general population, within-visit BPV at an initial visit is associated with within-visit BPV at subsequent visits and with visit-to-visit BPV over three visits within 1 week. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure measurement Source Type: research

Magnitude and significance of interarm blood pressure differences in children and adolescents
Conclusion: Substantial interarm BP differences were common, even in apparently healthy children and adolescents: evaluation of IAD may, therefore, be important for BP classification in the paediatric setting. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Blood pressure measurement Source Type: research

Development of integrated model of communication for implementing media strategy to prevent hypertension in a northern state of India
Conclusion: The present model can effectively be used by the program implementers, educators and policy makers in similar settings. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Diagnostic aspects Source Type: research

Validity of five formulas in estimating 24-h urinary sodium via spot urine sampling in hypertensive patients living in Northeast China
Conclusion: The INTERSALT method may exhibit a good performance in estimating 24-h urinary sodium level for the hypertensive population living in northeast China. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Diagnostic aspects Source Type: research

Low-blood pressure phenotype underpins the tendency to reflex syncope
Conclusion: The patients prone to reflex syncope demonstrate a different resting cardiovascular haemodynamic profile as compared with a general population, characterized by lower SBP and PP, reflecting reduced venous return and lower stroke volume, and a higher HR and DBP, suggesting the activation of compensatory mechanisms. Our data contribute to a better understanding why some individuals with similar demographic characteristics develop reflex syncope and others do not. Video abstract: http://links.lww.com/HJH/B580. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Diagnostic aspects Source Type: research

Basal septal hypertrophy in hypertension; about time to introduce an objective and reproducible quantification
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

Aortic strain in hypertensive patients, are we ready for it?
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

Postural blood pressure changes and arterial stiffness: a vicious circle?
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

High salt is a risk factor for cardiovascular and kidney diseases. What is next, fibrosis?
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

Cardiovascular system in the sars-CoV-2: impact of therapies
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

The interactions between antihypertensive drugs and novel anticancer therapy
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: EDITORIAL COMMENTARIES Source Type: research

2021 European Society of Hypertension practice guidelines for office and out-of-office blood pressure measurement
Collaborators: Lucas Aparicio (Argentina), Kei Asayama (Japan), Roland Asmar (France), Grzegorz Bilo (Italy), Jean-Marc Boivin (France), Alejandro de la Sierra (Spain), Eamon Dolan (Ireland), Jan Filipovsky (Czech Republic), Geoffrey Head (Australia), Yutaka Imai (Japan), Kazuomi Kario (Japan), Anastasios Kollias (Greece), Efstathios Manios (Greece), Klaus Matthias (Germany), Richard McManus (UK), Anastasia Mihailidou (Australia), Paul Muntner (USA), Martin Myers (Canada), Teemu Niiranen (Finland), Angeliki Ntineri (Greece), Takayoshi Ohkubo (Japan), Aleksander Prejbisz (Poland), Athanase Protogerou (Greece), Menno Pru...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: CONSENSUS DOCUMENT Source Type: research

Coronavirus disease 2019 and cardiovascular complications: focused clinical review
The coronavirus disease 2019 (COVID-19) may cause not only an acute respiratory distress syndrome (ARDS) but also multiple organ damage and failure requiring intensive care and leading to death. Male sex, advanced age, chronic lung disease, chronic kidney disease and cardiovascular disease, such as hypertension, diabetes and obesity have been identified as risk factors for the COVID-19 severity. Presumably, as these three cardiovascular risk factors are associated with a high prevalence of multiorgan damage. In the present focused clinical review, we will discuss the cardiovascular complications of COVID-19 including acute...
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: REVIEWS AND META-ANALYSES Source Type: research

Effect of concomitant use of antihypertensives and immune check point inhibitors on cancer outcomes
Conclusion: Concomitant use of antihypertensives including RASi was not associated with survival and immune-related safety outcomes during atezolizumab therapy for solid cancers. Future studies should evaluate the association between antihypertensives and other ICI as well as ICI combination interventions in clinical trials and real-world settings. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: REVIEWS AND META-ANALYSES Source Type: research

The differential impact of aerobic and isometric handgrip exercise on blood pressure variability and central aortic blood pressure
Conclusion: Aerobic exercise reduces blood pressure variability and central SBP. Isometric handgrip exercise does not reduce blood pressure variability but tends to lower central SBP in this hypertensive population. (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: REVIEWS AND META-ANALYSES Source Type: research

Highlights of the July issue
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - June 11, 2021 Category: Cardiology Tags: EDITOR'S CORNER Source Type: research

Reply
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

‘Apples to oranges’ and ‘Less is more’
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Reply
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Blood pressure and atrial fibrillation: a risk assessment
No abstract available (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: CORRESPONDENCE Source Type: research

Chlorthalidone versus hydrochlorothiazide: major cardiovascular events, blood pressure, left ventricular mass, and adverse effects
Conclusion: Over the short-term there were no differences in the net clinical benefit between HCTZ and CTD. However, long-term available data document CTD to be significantly more effective in reducing MACE than HCTZ. The Veterans Administration's trial in progress may provide definitive answer to these questions. (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Hemodynamic profiles in treatment-naive arterial hypertension and their clinical implication for treatment choice: an exploratory post hoc analysis
Conclusion: Our findings do not support the hypothesis that personalized treatment initiation based on hemodynamic profiles improves BP control in newly diagnosed hypertensive outpatients. (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Therapeutic inertia in the management of hypertension in primary care
Conclusion: Therapeutic inertia is common in primary care patients with uncontrolled hypertension. Older age, and closer to target BP, but also concurrent diabetes were associated with inertia. (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Mediterranean diet and antihypertensive drug use: a randomized controlled trial
Conclusion: In an older population at high cardiovascular risk, following a Mediterranean diet reduced the risk of initiating or escalating antihypertensive medication and attenuated cardiovascular risk in antihypertensive drug users. (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Blood pressure control and progression of arteriosclerosis in hypertension
Objective: Using the brachial--ankle pulse wave velocity (baPWV) as a biomarker for arteriosclerosis, we studied the effect of blood pressure (BP) and BP control on arteriosclerosis progression. Methods and results: The community-based longitudinal Kailuan study included 6552 participants [4938 (75.37%) men] with a mean follow-up of 4.62 ± 2.21 years. Hypertension was defined based on the Joint National Committee (JNC7) criteria and the 2017 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines. All study participants had hypertension and were stratified as follows according...
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Treatment Source Type: research

Incremental value of carotid elasticity modulus using shear wave elastography for identifying coronary artery disease in patients without carotid plaque
Conclusion: Carotid wall elastic modulus measured using SWE is a useful predictor of obstructive CAD in patients without carotid plaque. We demonstrated the incremental and independent value of carotid wall elastic modulus in identifying obstructive CAD compared with clinical risk factors and other imaging predictors, including ABI and GCCS. Video abstract: Please see the video, in Supplemental Digital Content 1, http://links.lww.com/HJH/B551 for more insights from the authors. (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Role of arterial stiffness in the association between hand grip strength and cardiovascular events: the Korean Genome and Epidemiology Study
Background: Hand grip strength (HGS) has been associated with cardiovascular events. However, the exact mechanism responsible for the inverse association between HGS and cardiovascular events has not been established. The aim of this study was to assess whether arterial stiffness mediates this association. Methods: We studied 1508 participants (age; 60 ± 5, men; 47.5%) from the Ansan cohort of the Korean Genome Epidemiology Study. Participants were assessed for various parameters of arterial stiffness as well as HGS. The augmentation index (AIx) and brachial-ankle pulse wave velocity (baPWV) were eval...
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

Neck-to-height ratio and arterial stiffness in Chinese adults: cross-sectional associations in a community-based cohort
Objectives: The aim of this study was to investigate the association between neck-to-height ratio (NHR) and arterial stiffness in adults from a community-based Chinese cohort in a cross-sectional study. Methods: We conducted cross-sectional analysis using data from the Kailuan study, a population-based cohort research. Altogether, 18 972 individuals were included in the analysis. Brachial ankle pulse wave velocity (baPWV), anthropometric indexes and cardiovascular risk factors were recorded. Data were analyzed by multiple lineal regression model. Results: NHR was positively associated with baPWV after a...
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Organ damage Source Type: research

The association between self-perceived walking pace with the incidence of hypertension: the ‘Seguimiento Universidad de Navarra’ cohort
Conclusion: Our results support that an increase in walking pace, even slightly, is inversely associated with the development of hypertension, independent of total time spent walking and other factors associated with hypertension. (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Risk factors Source Type: research

Associations of the nocturnal blood pressure fall and morning surge with cardiovascular events and mortality in individuals with resistant hypertension
Conclusion: Abnormal dipping patterns but not the early-morning BP surge, were important prognostic markers for future cardiovascular morbidity in RHT patients. The prognosis of extreme dippers depended on age and the presence of cardiovascular diseases. (Source: Journal of Hypertension)
Source: Journal of Hypertension - May 14, 2021 Category: Cardiology Tags: ORIGINAL PAPERS: Risk factors Source Type: research