Effectiveness of tonifying-kidney and regulating-liver therapy on diminished ovarian reserve: a systematic review and Meta-analysis of randomized controlled trials.
CONCLUSION: Compared with Western Medicine, tonifying-kidney and regulating-liver therapy is more effective at relieving symptoms and improving AFC and FSH at 3 months post-treatment. PMID: 32506847 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Liu L, Liu Y, Yang M, Xu G, Li R, Xu X, Pan X, Liang J Tags: J Tradit Chin Med Source Type: research

Effect and safety of acupotomy in treatment of knee osteoarthritis: a systematic review and Meta-analysis.
Abstract OBJECTIVE: To evaluate the clinical efficacy and safety of acupotomy in treatment of knee osteoarthritis (OA). METHODS: Extensive literature searches were carried out in PubMed, EMBASE, Cochrane Library (Issue 5, 2017), Chinese Biomedical Literature Database, China National Knowledge Infrastructure Database, China Science and Technology Journal Database and Wanfang Database. All databases were retrieved from their inception until May 31, 2017. Randomized controlled trials incorporating acupotomy versus intra-articular sodium hyaluronate for knee osteoarthritis were included. According to Cochrane Rev...
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Fang T, Li Q, Zhou F, Liu F, Liu Z, Zhao M, Chen M, You J, Jin Y, Xie J Tags: J Tradit Chin Med Source Type: research

Effect of supplementing Qi and promoting blood circulation therapy on left ventricular remodeling: a systematic review and Meta-analysis.
Abstract OBJECTIVE: To evaluate the effectiveness of an adjuvant therapy from Traditional Chinese Medicine for supplementing Qi and promoting blood circulation (CMSQPBC) on left ventricular remodeling in patients after myocardial infarction (MI). METHODS: Randomized controlled trials were identified in the Cochrane Library, Embase, Web of Science, PubMed, China National Knowledge Infrastructure Database, Chinese Biomedical Literature Database, China Science and Technology Journal Database, Wanfang databases, reviews, and reference lists of relevant articles. The weighted mean difference (WMD) was calculated f...
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Mao S, Zuo T, Jiang L, Zhang M Tags: J Tradit Chin Med Source Type: research

"Effects of extracts from Renshen (Radix Ginseng), Sanqi (Radix Notoginseng), and Chuanxiong (Rhizoma Chuanxiong) on F-actin in senescent microvascular endothelial cells".
CONCLUSION: The extracts delayed microvascular endothelial cell senescence by downregulating the expression of F-actin through HSP27. PMID: 32506850 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Wang Q, Yang J, Lei Y, Xiu C, Huo Y, Shi H Tags: J Tradit Chin Med Source Type: research

Three Tiaobu Feishen formulae reduces cigarette smoke-induced inflammation in human airway epithelial cells.
CONCLUSION: BJF, BYF, and YZF effectively suppressed inflammatory responses, protease-antiprotease imbalance, and oxidative stress induced by LPS and CSE, an effect that was closely associated with the inhibition of the NF-κB, MAPK, STAT3, and PPAR pathways. PMID: 32506851 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Dong H, Liu X, Zheng W, Feng S, Li J, Qin Y, Wu Y, Chen Y, Yin S, Zhao P Tags: J Tradit Chin Med Source Type: research

Antioxidant capacity of extract from Jiangtang Xiaozhi recipe in vitro.
CONCLUSION: JXR extract has significant antioxidant capacity in vitro. PMID: 32506852 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Song W, Yuan Y, Yu N, Gu H, Zhou Y, Chen X, Wang S, Fan K, Ge Z, Jin L, Xu Y Tags: J Tradit Chin Med Source Type: research

"Wang-Bi tablet, a patented Chinese medicine, maintains the balance of Th1/Th2 in mice with collagen-induced arthritis".
CONCLUSION: These results indicate that WBT may produce a therapeutic effect on CIA through maintaining the balance of Th1/Th2 cells, which could result in a decrease in the autoinflammatory disorder observed in RA. PMID: 32506853 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Wang J, Luo J, Xu Y, Yan Z, Qu X, Chen M, Tao Q Tags: J Tradit Chin Med Source Type: research

Electroacupuncture relieves irritable bowel syndrome by increasing expression of nucleotide-binding oligomerization domain protein-like receptor family pyrin domain containing 6 in water-avoidance stress mice.
CONCLUSION: Our study found that the relief of IBS symptoms by EA may involve the increase in the expression of NLRP6 in WAS mice. PMID: 32506854 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Song Y, Geng H, Chen L, Wu X, Yuan M, Sun J, Pei L, Xu W, Guo J Tags: J Tradit Chin Med Source Type: research

Danggui Buxue decoction ameliorates lipid metabolic defects involved in the initiation of diabetic atherosclerosis; identification of active compounds.
CONCLUSION: DBD affects lipid metabolism in the early stage of atherosclerosis in diabetic GK rats, with the mechanism likely involving the regulation of lipid metabolic genes in vessels. The contribution of ABCs to the effect of DBD on lipid metabolism was 24%-101%. PMID: 32506855 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Xue M, Bian Y, Liu Y, Zhou J, Xu J, Zhang L, Huang X Tags: J Tradit Chin Med Source Type: research

Osteoking downregulates Mgp in an osteoporotic fracture rat model.
Abstract OBJECTIVE: To investigate the effectiveness of osteoking, a Traditional Chinese Medicine originating from Yi nationality, against osteoporosis (OP) and osteoporotic fracture (OPF), and to elucidate its mechanism of action. METHODS: An osteoporotic fracture rat model was established; animals were divided into three treatment groups: parathyroid hormone, osteoking and 0.9%NaCl. After 4, 8 and 12 weeks of treatment, serum and bone tissues were collected. Enzyme-linked immuno sorbent assay, x-ray, histopathological evaluation and proteomics were used. Proteomics and GO annotation were performed based on ...
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Sun Y, Wang X, Chen R, Zhu D, Shen Z, Zhao H, Lee W Tags: J Tradit Chin Med Source Type: research

"Effectiveness of Jinying capsule on pelvic inflammatory disease in patients with symptom pattern of damp and heat accumulation: a double-blinded, multicenter, randomized, placebo-controlled clinical trial".
CONCLUSION: Jinying capsule can reduce the dosage of antibiotics needed for PID treatment, and improve the symptoms in PID patients. PMID: 32506857 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Yang Y, Lu Y, Zhou D, Pei F, Li Q, Chen S, Wang Q, Wang Y, Jin Z, Liu Y Tags: J Tradit Chin Med Source Type: research

Comparative efficacy of honey 12.5% and chlorhexidine 0.2% mouthwashes on the oropharyngeal bacterial colonization in mechanically-ventilated patients: a randomized controlled trial.
CONCLUSION: None of the studied solutions contributed to the reduction of oropharyngeal bacterial colonization. It seems that the growth inhibition of Staphylococcus aureus and Pseudomonas aeruginosa by the honey 12.5% mouthwash in mechanically-ventilated patients need further investigation. PMID: 32506858 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Halimeh A, Farhad RB, Naseh S, Karim N Tags: J Tradit Chin Med Source Type: research

Effectiveness and clinical benefit of a therapy of combined non-pharmaceutical Traditional Chinese Medicine for knee osteoarthritis: a randomized controlled study.
CONCLUSION: None of the studied solutions contributed to the reduction of oropharyngeal bacterial colonization. It seems that the growth inhibition of Staphylococcus aureus and Pseudomonas aeruginosa by the honey 12.5% mouthwash in mechanically-ventilated patients need further investigation. PMID: 32506859 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Zhang L, Yuan H Tags: J Tradit Chin Med Source Type: research

Wrist-ankle acupuncture and Fluoxetine in the treatment of post-stroke depression: a randomized controlled clinical trial.
CONCLUSION: The present study showed that WAA combined with fluoxetine can relieve the symptoms of depression after stroke. WAA therapy could improve the antidepressant effect of fluoxetine. PMID: 32506860 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: You Y, Zhang T, Shu S, Qian X, Zhou S, Yao F Tags: J Tradit Chin Med Source Type: research

Effect of Huatan Jieyu granules in treatment of Parkinson's disease patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind.
Abstract OBJECTIVE: To investigate the safety and efficacy of Huatan Jieyu granules in treatment of Parkinson's disease (PD) patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind in terms of the theory of Traditional Chinese Medicine. METHODS: In total, 107 Parkinson's disease patients with sleep disorders identified as symptom pattern of phlegma-heat-stirring wind were selected and randomly divided into the experimental group (55 cases) and the control group (52 cases). Both groups were given basic treatment with prednisone. The experimental group of patients was treated wi...
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Liu M, Hu C, Zhang Y, Li Q, Zhang Q, Fang Y, Sun H, Hou X, Jin S, Tao L, Yang D Tags: J Tradit Chin Med Source Type: research

"Enzymatic and non-enzymatic antioxidant, anti-inflammatory and anticancer activities of Floscopa scandens Lour".
CONCLUSION: The results revealed that the methanol extracts of F. scandens could be used as a potential source of antioxidant, anti-inflammatory and anticancer bioactive compounds. PMID: 32506863 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Anto Suganya R, Jeya Jothi G Tags: J Tradit Chin Med Source Type: research

"Possible mechanisms underlying treatment of Alzheimer's disease with Traditional Chinese Medicine: active components, potential targets and synthetic pathways of Bulao Elixir".
CONCLUSION: The current study elucidated the potential treatment mechanisms of Bulao Elixir in AD using network pharmacology, providing a foundation for further clarification of its treatment targets. PMID: 32506864 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2020 Category: Complementary Medicine Authors: Ren B, Cheng F, Wang X, Wan Y, Ji W, Du X, Zhang S, Liu S, Ma C, Xiong Y, Hao G, Wang Q Tags: J Tradit Chin Med Source Type: research

Comparative efficacy and safety of Chinese herbal injections combined with transcatheter hepatic arterial chemoembolization in treatment of liver cancer: a bayesian network Meta-analysis.
CONCLUSION: Our findings indicated that receiving CHIs combined with TACE may have therapeutic benefits for patients with liver cancer in improving survival rate, clinical effective rate, the performance status and alleviating the ADRs. PMID: 32242383 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Zhang D, Wang K, Zheng J, Wu J, Duan X, Ni M, Liu S, Zhang B, Zhao Y Tags: J Tradit Chin Med Source Type: research

Tonifying kidney therapy for stable chronic obstructive pulmonary disease: a systematic review.
Abstract OBJECTIVE: To evaluate the efficacy and safety of tonifying kidney therapy (Bushen, TK) for stable chronic obstructive pulmonary disease (COPD). METHODS: Randomized controlled trials (RCTs) of TK use for treatment of stable COPD were searched in four databases including PubMed, the Cochrane Library, Chinese Biomedical Literature Database, and China National Knowledge Infrastructure Database from inception to December 2017. Two reviewers independently screened the literature, extracted the data, and assessed the risk of bias in the included studies. RevMan 5.3 software was used for the Meta-analysis. ...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Gao Z, Liu Y, Xu Y, Dong J Tags: J Tradit Chin Med Source Type: research

Effects of a fermented buckwheat flower and leaf extract on the blood glucose and lipid profile of type 2 diabetic db/db mice.
CONCLUSION: These findings suggest that EFBFL has anti-diabetic effects in db/db mice, ameliorating glucose intolerance, lipid dysregulation, and insulin resistance. PMID: 32242385 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Wang J, Jiang Y, Wang Y, Yu X, Li Y, Han S Tags: J Tradit Chin Med Source Type: research

Notch signaling pathway mediates the immunomodulatory mechanism of Yangfei Huoxue decoction alleviating bleomycin-induced pulmonary fibrosis in rats.
CONCLUSION: The current study indicates that YHD mainly functions by regulating the immune system and that the molecular mechanism may be related to the regulation of the Notch signaling pathway. PMID: 32242386 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Chen H, Wu H, Sum G, Gong J, Liu X, Chang K, Su Y Tags: J Tradit Chin Med Source Type: research

Effects of modified Wenjing decoction on microcirculation in reproductive organs in rats with symptom patterns of cold coagulation and blood stasis.
CONCLUSION: Our findings suggest that the dysfunctional reproductive organs observed in gynecological CCBS may be closely related to the microcirculation disturbance of local tissues, microvascular contraction, and vascular remodeling. Modified WJD can be used to treat CCBS by improving microcirculation in reproductive organs. PMID: 32242387 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Wang D, Li X, Ren Y, Ren W, Xue B, Yang C, Fang H Tags: J Tradit Chin Med Source Type: research

Effect of Gubi prescription on caveolin-1 expression and phosphoinositide 3 kinase/protein kinase B and Fas signal pathways in rats with knee osteoarthritis.
Abstract OBJECTIVE: To investigate the effects of Gubi prescription on the expression of caveolin-1, and the phosphoinositide 3 kinase/protein kinase B (PI3K/Akt) and Fas signal pathways in rats with knee osteoarthritis (KOA). METHODS: Forty KOA model rats were established using a modification of Hulth's method. Rats were divided into five groups by the random number method: model, positive drug (Vicolli group), and high-, medium-, and low-dose Gubi prescription groups (n = 8/group). In the sham surgery group (n = 8), only anterior and posterior cruciate ligaments of rats were exposed during surgery. A normal...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: He X, Zhou X, Xu L, Cao J, Wang R, Wang M, Xie G, Wang L Tags: J Tradit Chin Med Source Type: research

Danggui Buxue Tang ameliorates bleomycin-induced pulmonary fibrosis in rats through inhibiting transforming growth factor- β1/Smad3/ plasminogen activator inhibitor-1 signaling pathway.
CONCLUSION: Our findings suggest that DBT is able to ameliorate the pulmonary fibrosis, the possible mechanism may involve inhibition of pulmonary inflammation and collagen deposition, possibly via suppressing TGF-β1/Smad3/PAI-1 signaling pathway. PMID: 32242389 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Wang J, Fang C, Wang S, Fang F, Chu X, Liu N, Lu C, Wang S, Li W, Fang C, Wang S Tags: J Tradit Chin Med Source Type: research

Effect of Tongxieyaofang decoction on colonic mucosal protein expression profiles in rats with visceral hypersensitivity.
; B Abstract OBJECTIVE: To explore the underlying mechanism of action of Tongxieyaofang decoction in rats with visceral hypersensitivity using proteomics technology. METHODS: Twenty-four female Sprague-Dawley rats were randomly divided into three groups: control group, irritable bowel syndrome (IBS) group and Tongxieyaofang treatment group. An IBS model, characterized as visceral hypersensitivity, was established using the odour of mothballs as conditional stimulation and colorectal distension combined with classic physical restraint as non-conditional stimulation. Rats were intragastrically treated with Tong...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Lin Y, Liu N, Ding Y, Lü B Tags: J Tradit Chin Med Source Type: research

Sini powder ameliorates the inflammatory response in rats with stress-induced non-alcoholic fatty liver disease by inhibiting the nuclear factor kappa-B / pyrin domain-containing protein 3 pathway.
Abstract OBJECTIVE: To evaluate the effectiveness of Sini powder for the treatment of non-alcoholic fatty liver disease (NAFLD) in rats and the molecular mechanisms involved. METHODS: A rat model of stress-induced NAFLD was established by a combination of long-term tethering and feeding of a high-fat, high-calorie diet. These rats were then intragastrically administered with either simvastatin, Sini powder, or vehicle for 1 week. The body mass and field test scores for each group were recorded weekly. Serum aspartate aminotransferase and alanine aminotransferase activities, and triglyceride, total cholesterol...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Mu J, Cheng F, Wang Q, Wang X, Zhu W, Ma C, Yin X, Ren B, Lian Y, Du X, Zhang H, Liu S, Zhang S Tags: J Tradit Chin Med Source Type: research

"Acupuncture stimulation of Yamen (GV 15), Fengfu (GV 16), Baihui (GV 20), Shuigou (GV 26) and Hegu (LI 4) reduces brain microglia activation in a traumatic brain injury rat model".
CONCLUSION: Acupuncture stimulating the Yamen (GV 15), Fengfu (GV 16), Baihui (GV 20), Shuigou (GV 26) and Hegu (LI 4) acupoints can effectively inhibit the development of neuroinflammation after TBI. One possible mechanism for this effect is that acupuncture downregulates LPA synthesis and affects the LPA-LPAR pathway by inhibiting LPAR1 and LPAR2, thereby inhibiting microglial activation and reducing neuroinflammation. PMID: 32242392 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Lin S, Zhu M, Chen W, Zhang Y, Lin J, Pu L, Chen S, Zhang Y, Liu X Tags: J Tradit Chin Med Source Type: research

Effect of acupuncture therapy on fracture healing in rats with femur fractures.
CONCLUSION: The acupuncture therapy can affect suppression of the effects of free oxygen radicals and regulation of the antioxidant enzyme activity in fracture healing. Thus, it is suggested that acupuncture treatment would be beneficial for fracture healing in order to eliminate the negative effects induced by oxygen free radicals. PMID: 32242393 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Seval Y, Emre K, Erhan Y, Suleyman G, Ahmet K, Mustafa O Tags: J Tradit Chin Med Source Type: research

"Efficacy and safety of Xinfeng capsule in the treatment of osteoarthritis: a multicenter, randomized, double-blinded, controlled trial".
CONCLUSION: XFC is effective and safe in the treatment of OA. XFC was superior to GS in improving the WOMAC index total score, WOMAC scores for pain, stiffness, and function, visual analogue scale for pain, Lequesne index, and Short Form-36 quality of life. PMID: 32242394 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Liu J, Wang Y, Sun Y, Huang C, Chen X, Zhang W, He L, James Cheng-Chung W Tags: J Tradit Chin Med Source Type: research

"Efficacy and safety of Liangxue Jiedu decoction for the treatment of progressive psoriasis vulgaris: a multicenter, randomized, controlled study".
"Efficacy and safety of Liangxue Jiedu decoction for the treatment of progressive psoriasis vulgaris: a multicenter, randomized, controlled study". J Tradit Chin Med. 2020 Apr;40(2):296-304 Authors: Sun L, Zhou D, Wang P, Li T, Xu X, Yang X, Tian J, Zhao J, He Y, Liu F, Tong C, Chu X, Dai L, Zhu W Abstract OBJECTIVE: To determine the clinical efficacy and safety of Liangxue Jiedu decoction (LJD) for the treatment of progressive psoriasis vulgaris and to provide the basis for the development of a standardized treatment protocol for psoriasis vulgaris. METHODS: In this multicenter, random...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Sun L, Zhou D, Wang P, Li T, Xu X, Yang X, Tian J, Zhao J, He Y, Liu F, Tong C, Chu X, Dai L, Zhu W Tags: J Tradit Chin Med Source Type: research

Effect of Lingqi Huangban granule plus intravitreal ranibizumab on macular edema induced by retinal vein occlusion: a randomized controlled clinical trial.
Abstract OBJECTIVE: To investigate the effect of Lingqi Huangban granule (LQHB) plus intravitreal ranibizumab in the treatment of macular edema (ME) induced by retinal vein occlusion (RVO). METHODS: A prospective, randomized controlled study was conducted. A total of 60 subjects with RVO induced ME were randomized into control group (CG) (30 eyes) and LQHB group (LQHBG) (30 eyes). CG patients underwent intravitreal ranibizumab (IVR) injections. LQHBG patients were treated with oral LQHB combined with IVR injections. In order to reduce the financial burden of the injections, we used one injection and pro re na...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Lu B, Wu X Tags: J Tradit Chin Med Source Type: research

Transforming growth factor β1 is a differentially expressed candidate protein of congestive heart failure with Qi-deficiency-blood-stasis syndrome.
CONCLUSION: Occurrence and development of CHF may result from certain DE-proteins and associated signaling pathways. TGF-β1 protein may be a candidate marker for assessing the risk of CHF in Qi-deficiency-blood-stasis syndrome. PMID: 32242397 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Li X, Huang P, He J, Wang S, Cao X Tags: J Tradit Chin Med Source Type: research

"Efficacy and safety of the Qiguiyin formula in severe pneumonia: study protocol for a randomized, double-blind, placebo-controlled clinical trial".
"Efficacy and safety of the Qiguiyin formula in severe pneumonia: study protocol for a randomized, double-blind, placebo-controlled clinical trial". J Tradit Chin Med. 2020 Apr;40(2):317-323 Authors: Huang P, Guo Y, Wu Y, Liu Q, Zhao J, Li B Abstract OBJECTIVE: To evaluate the clinical efficacy and safety of Qiguiyin (QGY) formula in patients with severe pneumonia in China compared with a placebo. METHODS: This is a multicenter double-blind, placebo-controlled, randomized clinical trial with two parallel arms. There will be 530 patients enrolled and randomized into either the experiment...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Huang P, Guo Y, Wu Y, Liu Q, Zhao J, Li B Tags: J Tradit Chin Med Source Type: research

Effect of herb-partitioned moxibustion on pain and quality of life in women with endometriosis: a protocol for a randomized clinical trial.
CONCLUSION: This study will provide evidence to confirm if HPM may be used as a therapeutic option for treating endometriosis. PMID: 32242399 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Hu H, Chen L, Jin X, Li R, Fang J Tags: J Tradit Chin Med Source Type: research

Effect of plum-blossom needling versus tropicamide eye drops on adolescent myopia: protocol for a randomized crossover trial.
DISCUSSION: The results of the trial will help to provide evidence for the efficacy of plum-blossom needling for myopia in China. PMID: 32242400 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Chen L, Liang Y, Zheng J, Xu M, Yu H, Tang L Tags: J Tradit Chin Med Source Type: research

Treatment of dilated cardiomyopathy caused by coronary microvascular dysfunction with anisodamine: a report of 5 cases.
Abstract The management of dilated cardiomyopathy (DCM) is well established. However, a subset of patients does not have recovery from or have recurrences of left ventricular (LV) dysfunction despite receiving optimal medical therapy. Coronary microvascular dysfunction (CMD) can result from structural and functional abnormalities at the intramural and small coronary vessel level affecting coronary blood flow autoregulation and consequently leading to impaired coronary flow reserve. Dilated myocardial phenotype may be responsible for CMD in DCM. Anisodamine can exert a significant effect on relieving microvascular ...
Source: Journal of Traditional Chinese Medicine - April 1, 2020 Category: Complementary Medicine Authors: Xu Z, Wang T, Chen L, Lou Y, Jiang J, Sun X Tags: J Tradit Chin Med Source Type: research

"J Tradit Chin Med"[ta]; +109 new citations
109 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "J Tradit Chin Med"[ta] These pubmed results were generated on 2020/03/21PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 21, 2020 Category: Complementary Medicine Tags: Report Source Type: research

"J Tradit Chin Med"[ta]; +108 new citations
108 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: "J Tradit Chin Med"[ta] These pubmed results were generated on 2020/03/19PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 19, 2020 Category: Complementary Medicine Tags: Report Source Type: research

Comparison of the effect and safety of Kuntai capsule and hormone replacement therapy in patients with perimenopausal syndrome: a systematic review and Meta-analysis.
Abstract OBJECTIVE: To assess the effectiveness and safety of Kuntai capsule and hormone replacement therapy in treatment of perimenopausal syndrome. METHODS: Articles were retrieved from the databases Cochrane Database of Systematic Reviews, PubMed, Chinese National Knowledge Infrastructure, China Science and Technology Journal Database, and Wanfang Database. Only randomized controlled trials were included; 15 trials involving 1243 patients were identified from January 2005 to April 2015. A systemic review and Meta-analysis of publications was performed. The review was limited to randomized controlled trials...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Du X, Xu L, Wang L, Heng M, Bu H, Hao Y, Tian J Tags: J Tradit Chin Med Source Type: research

Clinical characteristics of 96 patients with drug-induced acute liver failure: a comparison between Traditional Chinese and Western Medicine.
CONCLUSION: TCM-induced ALF was more likely to be accompanied by renal injury than was WM-induced ALF, especially in TCM-induced ALF patients who died. PMID: 31682370 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: He T, Zhu Y, Gong M, Wang R, Jing J, Wang L, Wang Z, Zhang N, Bai Y, Li Y, Wang J, Niu M, Bai Z, Xiao X Tags: J Tradit Chin Med Source Type: research

Effects of three needling manipulations of the right-side Zusanli (ST 36) on brain using functional magnetic resonance imaging.
CONCLUSION: Three methods of needling manipulations similarly activated areas associated with the somatosensory system, vision, cognition, and emotional regulation. This may have significant implications for acupuncture in clinical practice. PMID: 31682371 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Lu F, Gao J, Wang Y, Dai Q, Xin J, Zhao Y, Wu S, Yu X, Bao Y, Hong Y, Zhang G, Chen Y, Li X, Fang J Tags: J Tradit Chin Med Source Type: research

Velvet antler polypeptide is able to induce differentiation of neural stem cells towards neurons in vitro.
CONCLUSION: Differentiation of NSCs towards neurons can be induced by velvet antler polypeptide. PMID: 31682372 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Zhang L, Zhuang Z, Sun Y, Ma S, Yang W, Lei H, Ouyang J, Wang Y, Zuo J Tags: J Tradit Chin Med Source Type: research

Effect of Sophora flavescens alkaloid on aerobic vaginitis in gel form for local treatment.
CONCLUSION: The SFA gel is a promising medicine for local treatment of AV with the advantages of anti-bacteria, protection of vaginal mucosa, increase of Lactobacilli, and long retention time in the vaginal cavity. PMID: 31682373 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Wang X, Chen W, Jin Y, Li J, Hu Y Tags: J Tradit Chin Med Source Type: research

Effect of quercetin on secretion and gene expression of leptin in breast cancer.
Abstract OBJECTIVE: To investigate the possible inhibitory action of pure quercetin on secretion and gene expression of leptin in the T47D breast cancer cell line. METHODS: In this experimental study, T47D cells were cultured in monolayers in RPMI 1640. IC50 was determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay after 24 h treatment at different concentrations of quercetin. The levels of leptin gene expression were measured by reverse-transcription real-time polymerase chain reaction (PCR). Secreted leptin was measured in the supernatant of cells by an enzyme-linked immuno ...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Rahimifard M, Sadeghi F, Asadi-Samani M, Nejati-Koshki K Tags: J Tradit Chin Med Source Type: research

Anti-embolic effect of Taorenchengqi Tang in rats with embolic stroke induced by occluding middle cerebral artery.
Abstract OBJECTIVE: To investigate the anti-embolic effect of Taorenchengqi Tang (TRCQT), a formulas from Traditional Chinese Medicine, plus aspirin in rats with embolic stroke induced by selective occlusion of the middle cerebral artery (MCA). Possible side effects of hemorrhagic incident and other bleeding events and anti-platelet effect were also explored. METHODS: Ninety rats were randomly separated into 9 groups (n = 10): group 1 a sham-operated group (n = 10); groups 2 and 3 orally treated with an isovolumetric solvent (distilled water) for 1 and 3 months, followed by thromboembolic occlusion (n = 10); ...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Li J, Chang T, Chang N, Li J, Thanasekaran J, Chang CC Tags: J Tradit Chin Med Source Type: research

Neuroprotective effect of Naomaitong extract following focal cerebral ischemia induced by middle cerebral artery occlusion in rats.
CONCLUSION: These data demonstrate that extract from Naomaitong is neuroprotective against focal cerebral ischemia induced by MCAO, and can alleviate biochemical changes in urinary metabolism. Metabonomics may be a useful approach for assessing the biochemical mechanisms underlying the neuroprotective actions of extract from Naomaitong. PMID: 31682376 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Yang Y, Chen X, Wang S, Wang Z, Liang S, Li J Tags: J Tradit Chin Med Source Type: research

Differential gene expression profile of Buyanghuanwu decoction in rats with ventricular remodeling post-myocardial infarction.
CONCLUSION: The DGE profiling data provide comprehensive gene expression information at the transcriptional level that could facilitate our understanding of the pharmacological mechanisms of BYHWD in ventricular remodeling post-myocardial infarction. PMID: 31682377 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Zhang T, Hua Y, Luo H, Chen H, Shao M, Zhou Y, Liu B, Fu X, Huang G, John Man-Tak C, Huang G Tags: J Tradit Chin Med Source Type: research

Curcumin co-treatment ameliorates resistance to gefitinib in drug- resistant NCI-H1975 lung cancer cells.
Abstract OBJECTIVE: To examine whether a combinative treatment with curcumin enhances the effects of the epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) gefitinib on cell proliferation, clonogenic capacity and apoptosis in the drug-resistant lung cancer cell line NCI-H1975, and further investigate the molecular mechanisms involved. METHODS: NCI-H1975 cells were treated with curcumin and gefitinib alone or in combination, and cell proliferation, clonogenic capacity and apoptosis were examined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, clone forming...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Jin X, Wang J, Shen H, Ran R, Xu K, Zhang W, Tong X, Feng L Tags: J Tradit Chin Med Source Type: research

Tangnaikang improves insulin resistance and β-cell apoptosis by ameliorating metabolic inflammation in SHR.Cg-Leprcp/NDmcr rats.
CONCLUSION: TNK was able to improve insulin resistance and B-cell apoptosis in SHR-cp rats, which might be associated with its ability to relieve the overall and local metabolic inflammatory responses observed in SHR-cp rats. PMID: 31682379 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Li L, Qin L, Wu X, Wang H, Jiang Y, Wei Y, Xu T, Liu T, Yoshitomi H, Gao M, Zhou T Tags: J Tradit Chin Med Source Type: research

Lipopolysaccharide/Toll-like receptor 4 signaling pathway involved Qingdu decoction treating severe liver injury merging with endotoxemia.
Abstract OBJECTIVE: To investigate the protective effects and underlying mechanism of Qingdu decoction (QDD) on experimental rats with severe liver injury induced by thioacetamide (TAA). METHODS: A total of 40 Wistar rats were randomly divided into normal group (n = 10) and experimental group (n = 30). Rats were administrated the same content of saline in normal group. The rats in the experimental group were pretreated with TAA at dose of 12 mg/kg lasting 8 weeks, and from 9th week to 12th week, with TAA at concentration of 36 mg/kg. During the 9th week to 12th week period, the rats were randomly divided into...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Cao W, Du Y, Gao L, Che N, Zhang Q, Luo J, Cao W, Fu X, Wang R Tags: J Tradit Chin Med Source Type: research