Comparison of the effect and safety of Kuntai capsule and hormone replacement therapy in patients with perimenopausal syndrome: a systematic review and Meta-analysis.
Abstract OBJECTIVE: To assess the effectiveness and safety of Kuntai capsule and hormone replacement therapy in treatment of perimenopausal syndrome. METHODS: Articles were retrieved from the databases Cochrane Database of Systematic Reviews, PubMed, Chinese National Knowledge Infrastructure, China Science and Technology Journal Database, and Wanfang Database. Only randomized controlled trials were included; 15 trials involving 1243 patients were identified from January 2005 to April 2015. A systemic review and Meta-analysis of publications was performed. The review was limited to randomized controlled trials...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Du X, Xu L, Wang L, Heng M, Bu H, Hao Y, Tian J Tags: J Tradit Chin Med Source Type: research

Clinical characteristics of 96 patients with drug-induced acute liver failure: a comparison between Traditional Chinese and Western Medicine.
CONCLUSION: TCM-induced ALF was more likely to be accompanied by renal injury than was WM-induced ALF, especially in TCM-induced ALF patients who died. PMID: 31682370 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: He T, Zhu Y, Gong M, Wang R, Jing J, Wang L, Wang Z, Zhang N, Bai Y, Li Y, Wang J, Niu M, Bai Z, Xiao X Tags: J Tradit Chin Med Source Type: research

Effects of three needling manipulations of the right-side Zusanli (ST 36) on brain using functional magnetic resonance imaging.
CONCLUSION: Three methods of needling manipulations similarly activated areas associated with the somatosensory system, vision, cognition, and emotional regulation. This may have significant implications for acupuncture in clinical practice. PMID: 31682371 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Lu F, Gao J, Wang Y, Dai Q, Xin J, Zhao Y, Wu S, Yu X, Bao Y, Hong Y, Zhang G, Chen Y, Li X, Fang J Tags: J Tradit Chin Med Source Type: research

Velvet antler polypeptide is able to induce differentiation of neural stem cells towards neurons in vitro.
CONCLUSION: Differentiation of NSCs towards neurons can be induced by velvet antler polypeptide. PMID: 31682372 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Zhang L, Zhuang Z, Sun Y, Ma S, Yang W, Lei H, Ouyang J, Wang Y, Zuo J Tags: J Tradit Chin Med Source Type: research

Effect of Sophora flavescens alkaloid on aerobic vaginitis in gel form for local treatment.
CONCLUSION: The SFA gel is a promising medicine for local treatment of AV with the advantages of anti-bacteria, protection of vaginal mucosa, increase of Lactobacilli, and long retention time in the vaginal cavity. PMID: 31682373 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Wang X, Chen W, Jin Y, Li J, Hu Y Tags: J Tradit Chin Med Source Type: research

Effect of quercetin on secretion and gene expression of leptin in breast cancer.
Abstract OBJECTIVE: To investigate the possible inhibitory action of pure quercetin on secretion and gene expression of leptin in the T47D breast cancer cell line. METHODS: In this experimental study, T47D cells were cultured in monolayers in RPMI 1640. IC50 was determined by MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide) assay after 24 h treatment at different concentrations of quercetin. The levels of leptin gene expression were measured by reverse-transcription real-time polymerase chain reaction (PCR). Secreted leptin was measured in the supernatant of cells by an enzyme-linked immuno ...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Rahimifard M, Sadeghi F, Asadi-Samani M, Nejati-Koshki K Tags: J Tradit Chin Med Source Type: research

Anti-embolic effect of Taorenchengqi Tang in rats with embolic stroke induced by occluding middle cerebral artery.
Abstract OBJECTIVE: To investigate the anti-embolic effect of Taorenchengqi Tang (TRCQT), a formulas from Traditional Chinese Medicine, plus aspirin in rats with embolic stroke induced by selective occlusion of the middle cerebral artery (MCA). Possible side effects of hemorrhagic incident and other bleeding events and anti-platelet effect were also explored. METHODS: Ninety rats were randomly separated into 9 groups (n = 10): group 1 a sham-operated group (n = 10); groups 2 and 3 orally treated with an isovolumetric solvent (distilled water) for 1 and 3 months, followed by thromboembolic occlusion (n = 10); ...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Li J, Chang T, Chang N, Li J, Thanasekaran J, Chang CC Tags: J Tradit Chin Med Source Type: research

Neuroprotective effect of Naomaitong extract following focal cerebral ischemia induced by middle cerebral artery occlusion in rats.
CONCLUSION: These data demonstrate that extract from Naomaitong is neuroprotective against focal cerebral ischemia induced by MCAO, and can alleviate biochemical changes in urinary metabolism. Metabonomics may be a useful approach for assessing the biochemical mechanisms underlying the neuroprotective actions of extract from Naomaitong. PMID: 31682376 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Yang Y, Chen X, Wang S, Wang Z, Liang S, Li J Tags: J Tradit Chin Med Source Type: research

Differential gene expression profile of Buyanghuanwu decoction in rats with ventricular remodeling post-myocardial infarction.
CONCLUSION: The DGE profiling data provide comprehensive gene expression information at the transcriptional level that could facilitate our understanding of the pharmacological mechanisms of BYHWD in ventricular remodeling post-myocardial infarction. PMID: 31682377 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Zhang T, Hua Y, Luo H, Chen H, Shao M, Zhou Y, Liu B, Fu X, Huang G, John Man-Tak C, Huang G Tags: J Tradit Chin Med Source Type: research

Curcumin co-treatment ameliorates resistance to gefitinib in drug- resistant NCI-H1975 lung cancer cells.
Abstract OBJECTIVE: To examine whether a combinative treatment with curcumin enhances the effects of the epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) gefitinib on cell proliferation, clonogenic capacity and apoptosis in the drug-resistant lung cancer cell line NCI-H1975, and further investigate the molecular mechanisms involved. METHODS: NCI-H1975 cells were treated with curcumin and gefitinib alone or in combination, and cell proliferation, clonogenic capacity and apoptosis were examined using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, clone forming...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Jin X, Wang J, Shen H, Ran R, Xu K, Zhang W, Tong X, Feng L Tags: J Tradit Chin Med Source Type: research

Tangnaikang improves insulin resistance and β-cell apoptosis by ameliorating metabolic inflammation in SHR.Cg-Leprcp/NDmcr rats.
CONCLUSION: TNK was able to improve insulin resistance and B-cell apoptosis in SHR-cp rats, which might be associated with its ability to relieve the overall and local metabolic inflammatory responses observed in SHR-cp rats. PMID: 31682379 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Li L, Qin L, Wu X, Wang H, Jiang Y, Wei Y, Xu T, Liu T, Yoshitomi H, Gao M, Zhou T Tags: J Tradit Chin Med Source Type: research

Lipopolysaccharide/Toll-like receptor 4 signaling pathway involved Qingdu decoction treating severe liver injury merging with endotoxemia.
Abstract OBJECTIVE: To investigate the protective effects and underlying mechanism of Qingdu decoction (QDD) on experimental rats with severe liver injury induced by thioacetamide (TAA). METHODS: A total of 40 Wistar rats were randomly divided into normal group (n = 10) and experimental group (n = 30). Rats were administrated the same content of saline in normal group. The rats in the experimental group were pretreated with TAA at dose of 12 mg/kg lasting 8 weeks, and from 9th week to 12th week, with TAA at concentration of 36 mg/kg. During the 9th week to 12th week period, the rats were randomly divided into...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Cao W, Du Y, Gao L, Che N, Zhang Q, Luo J, Cao W, Fu X, Wang R Tags: J Tradit Chin Med Source Type: research

Effect of Yiqihuoxue prescription on myocardial energy metabolism after myocardial infarction via cross talk of liver kinase B1-dependent Notch1 and adenosine 5'-monophosphate-activated protein kinase.
CONCLUSION: YQHX promoted cross talk between the LKB1-dependent Notch1 and AMPK in myocardial tissue after myocardial infarction. Furthermore, it regulated the glucose and lipid metabolism of cardiomyocytes at different time points, thereby ameliorating the cardiac energy metabolism via different mechanisms and protecting the heart. PMID: 31682381 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Wu J, Chen X, Guo S, Liu W, Zhang L, Li F, Wu J, Huang X, Cai Q, Tan X, Wang H Tags: J Tradit Chin Med Source Type: research

Protective effect of Sharbat-e-Deenar against acetaminophen-induced hepatotoxicity in experimental animals.
CONCLUSION: On the basis of these results, it can be concluded that SD exerts hepatoprotective activity against APAP-induced liver injury. PMID: 31682382 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Arvind Kumar S, Sangeeta S Tags: J Tradit Chin Med Source Type: research

Colon hydrotherapy plus Traditional Chinese Medicine to treat non-alcoholic fatty liver disease: a pilot study.
CONCLUSION: Our findings suggest that CHT plus TCM to treat NAFLD is promising and it might be a new treatment strategy for management of NAFLD. PMID: 31682383 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Xiao H, Jiang J, Xie Y, Shi M, Tian G, Zhao P, Zhang C, Chen H, Xu C, Chi X Tags: J Tradit Chin Med Source Type: research

Xiyanping injection therapy for children with mild hand foot and mouth disease: a randomized controlled trial.
Abstract OBJECTIVE: To evaluate the clinical effects of Xiyanping injection intervention in pediatric patients with mild hand foot and mouth disease (HFMD). METHODS: A total of 329 patients were stratified and block-randomized for symptomatic treatment of HFMD and assigned to one of the following groups: Western Medicine (group A, n = 103), Xiyanping injection (group B, n = 109), or Xiyanping injection and symptomatic treatment using Western Medicine (group C, n = 117). During the trial, fever, rash, ulcers of the mouth were observed among participants in each group before and after treatment, and conversion ...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Zhang G, Hou Y, Li Y, He L, Tang L, Yang T, Zou X, Zhu Q, Yan S, Huang B, Zhao J, Huang J Tags: J Tradit Chin Med Source Type: research

Acupotomy versus sodium hyaluronate for treatment of knee osteoarthritis in rabbits.
Abstract OBJECTIVE: To investigate the possible advantages of acupotomy over sodium hyaluronate injection for the treatment of knee osteoarthritis (KOA). METHODS: Twenty rabbits were divided randomly into four groups (n = 5 in each): a control group, model group, acupotomy group, and sodium hyaluronate injection group. The model, acupotomy, and sodium hyaluronate groups underwent anterior cruciate ligament transection plus partial medial meniscectomy. Sodium hyaluronate injection and acupotomy were administered to the respective groups from weeks 5 to 8, and samples of the tibial plateau and medial condyle of...
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Ding Y, Shi X, Wang L, Daniela L, Gerhard L, Yuan X, Wang Y, Wang A, Wang L, Irmgard Th L Tags: J Tradit Chin Med Source Type: research

Baicalin and rutin are major constituents in Shuanghuanglian injection involving anaphylactoid reaction.
CONCLUSION: Baicalin and rutin from SHLI were the main constituents involving anaphylactoid reaction. PMID: 31682386 [PubMed] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2017 Category: Complementary Medicine Authors: Zhang Q, Cai C, Wang P, Ding N, Gao J, Zhang Y, Ma Z, Lei H, Li Q, Jian L, Si Y Tags: J Tradit Chin Med Source Type: research

Mechanism of herbal pairs with the properties of Qi-tonifying, blood activation, blood-stasis breaking in treating coronary heart disease.
i Y PMID: 29961275 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - April 1, 2017 Category: Complementary Medicine Authors: Yang J, Li J, Li L, Zhao N, Niu X, He X, Jiang M, Lü A, Lei Y Tags: J Tradit Chin Med Source Type: research

Gualoupi (Pericarpium Trichosanthis) injection in combination with convention therapy for the treatment of angina pectoris: a Meta- analysis.
CONCLUSION: PTI was found to be effective and safe for the treatment of angina pectoris. This study had certain limitations; thus, more rigorously designed, multi-center, randomized controlled trials in larger populations should be performed to support this observation. PMID: 29956895 [PubMed - as supplied by publisher] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Zhu Y, Xia W, Liu W, Xu C, Gu N Tags: J Tradit Chin Med Source Type: research

Sini decoction as an adjuvant therapy for angina pectoris: a systematic review of randomized controlled trials.
CONCLUSION: Based on this systematic review, Sini decoction can reduce the dosage of nitroglycerin, when compared with isosorbide dinitrate group. And there were no enough evidence in the papers to draw any conclusions for the safety of Sini decoction. PMID: 29956897 [PubMed - as supplied by publisher] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Wu J, Yuan D, Yang M, Xia W, Zhang Z, Zhang H, Fei Y, Yang G Tags: J Tradit Chin Med Source Type: research

Effect of Guizhi Gancao Longgu Muli Tang on sleep disturbances in menopausal women.
CONCLUSION: For menopausal women suffering from chronic sleep disturbances, our findings suggest that two weeks treatment of GGLMT was safe and effective. PMID: 29956898 [PubMed - as supplied by publisher] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Wang Z, Ke D, Huang X, Ding Y, Wang C Tags: J Tradit Chin Med Source Type: research

Effects of Yishengukang decoction on expression of bone-specific alkaline phosphatase, carboxyterminal propeptide of type Ⅰ procollagen, and carboxyterminal cross-linked telepeptide of type Ⅰ collagen in malignant tumor patients with bone metastasis.
CONCLUSION: Yishengukang decoction combined with pamidronate disodium injection reduced serum BAP level to a greater extent that pamidronate disodium injection alone. Furthermore, the combined therapy was more beneficial in regulating imbalanced bone metabolism after bone metastasis, and may represent the molecular mechanism underpinning the effects of Yishengukang decoction. PMID: 29956899 [PubMed - as supplied by publisher] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Yin Y, Feng L, Zhou L, Li J, Gao Y, Wang N, Yu J, Jiang Z, He S, Lu DR, Wang F, Du Y Tags: J Tradit Chin Med Source Type: research

Effects of Shengjiangxiexin decoction on irinotecan-induced toxicity in patients with UGT1A1*28 and UGT1A1*6 polymorphisms.
CONCLUSION: SXD could significantly reduce irinotecan-induced hematological and gastrointestinal toxicities in UGT1A1*28 or *6 variant patients (high risk group), while this treatment didn't affect clinical response of chemotherapy. PMID: 29956901 [PubMed - as supplied by publisher] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Deng B, Jia L, Tan H, Lou Y, Li X, Li Y, Yu L Tags: J Tradit Chin Med Source Type: research

Effect of electro-acupuncture combined with psychological intervention on mental symptoms and P50 of auditory evoked potential in patients with internet addiction disorder.
Abstract OBJECTIVE: To observe the therapeutic effects of electro-acupuncture (EA) combined with psychological intervention on the symptom of somzatization or obsession and mental symptom of depression or anxiety and P50 of Auditory Evoked Potential (AEP) on internet addiction disorder (IAD). METHODS: One hundred and twenty cases of IAD ere randomly divided into an EA group, a psycho- intervention (PI) group and a comprehensive therapy (EA plus PI) group. Patients in the EA group were treated with EA. Patients in the PI group were treated with cognition and behavior therapy. Patients in the EA plus PI group w...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Li H, Jin R, Yuan K, Zheng B, Zheng Z, Luo Y, Ye H, Huang B, Zhu T Tags: J Tradit Chin Med Source Type: research

Guasha improves the rating of perceived exertion scale score and reduces heart rate variability in male weightlifters: a randomized controlled trial.
Abstract OBJECTIVE: To evaluate the effects of Guasha therapy on the rating of perceived exertion (RPE) scale score, and heart rate variability (HRV). METHODS: A randomized controlled trial of Guasha (skin scraping) was compared with a sham scraping group and control group. Sixteen sessions within an 8-week period were completed. Sixty-five male weightlifters who had undergone normal weightlifting training for a mean of 5 years before study commencement were recruited. The RPE scale score of "snatch", "clean and jerk" maneuvers (85% of one-repetition maximum), and HRV were measured before ...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Wang X, Chen P, Huang X, Wang Y, Yang J, Wichai E, Yang Y, Uraiwan C Tags: J Tradit Chin Med Source Type: research

Protective effect of essential oil of Pistacia atlantica Desf. on peptic ulcer: role of α-pinene.
Protective effect of essential oil of Pistacia atlantica Desf. on peptic ulcer: role of α-pinene. J Tradit Chin Med. 2017 Feb;37(1):57-63 Authors: Memariani Z, Sharifzadeh M, Bozorgi M, Hajimahmoodi M, Farzaei MH, Gholami M, Siavoshi F, Saniee P Abstract OBJECTIVE: To evaluate the efficacy of Pistacia atlantica Desf. oleoresin essential oil on peptic ulcer (PU) and its antibacterial effect on metronidazole-resistant Helicobacter pylori, as well as chemical composition of the essential oil. METHODS: The essential oil was standardized using gas chromatography mass spectrometry (GC/MS) analys...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Memariani Z, Sharifzadeh M, Bozorgi M, Hajimahmoodi M, Farzaei MH, Gholami M, Siavoshi F, Saniee P Tags: J Tradit Chin Med Source Type: research

Effect on platelet aggregation activity: extracts from 31 Traditional Chinese Medicines with the property of activating blood and resolving stasis.
CONCLUSION: The study provided scientific references that several TCMs such as Chuanxiong (Rhizoma Chuanxiong), Yanhusuo (Rhizoma Corydalis Yanhusuo) and Danshen (Radix Salviae Miltiorrhizae), possess the property of anti-platelet aggregation. PMID: 29957905 [PubMed - as supplied by publisher] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Chen C, Wang F, Xiao W, Xia Z, Hu G, Wan J, Yang F Tags: J Tradit Chin Med Source Type: research

Effect of brain functional recovery decoction on expression of vascular endothelial growth factor and Ang-1 protein in a rat cerebral ischemia reperfusion model.
Abstract OBJECTIVE: To investigate the effect of brain functional recovery decoction (BFRD) on expression of vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang-1) protein in rats with cerebral ischemia reperfusion injury, and to explore the mechanism of action of BFRD. METHODS: Using the suture-occlusion method, a Wistar rat model of focal cerebral ischemia reperfusion was established. The rats were randomly divided into treatment group, model group, and sham operation group. The treatment group was administered BFRD. In situ hybridization was used to detect VEGF mRNA expression. Immunohistoche...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Yang B, Zhang C, Yang L, Yang J, Xiao G Tags: J Tradit Chin Med Source Type: research

Effect of brain functional recovery decoction on expression of vascular endothelial growth factor and Ang-1 protein in a rat cerebral ischemia reperfusion model.
Abstract OBJECTIVE: To investigate the effect of brain functional recovery decoction (BFRD) on expression of vascular endothelial growth factor (VEGF) and angiopoietin-1 (Ang-1) protein in rats with cerebral ischemia reperfusion injury, and to explore the mechanism of action of BFRD. METHODS: Using the suture-occlusion method, a Wistar rat model of focal cerebral ischemia reperfusion was established. The rats were randomly divided into treatment group, model group, and sham operation group. The treatment group was administered BFRD. In situ hybridization was used to detect VEGF mRNA expression. Immunohistoche...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Yang B, Zhang C, Yang L, Yang J, Xiao G Tags: J Tradit Chin Med Source Type: research

Shenfuqiangxin Capsule inhibits apoptosis through mitogen-activated protein kinase signal pathway in rats with cardio-renal syndrome induced by infrarenal aortic-clamping.
CONCLUSION: All the results suggest that Shenfuqiangxin capsule improves the injured heart and kidney function maybe through inhibition of MAPK response pathway. PMID: 29957913 [PubMed - as supplied by publisher] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Wang L, Wang Z, Yuan L, Hao D, Lü N, Li X Tags: J Tradit Chin Med Source Type: research

Efficacy of Ciji Hua'ai Baosheng formula on the expressions of vascular endothelial growth factor, kinase insert domain-containing receptor and basic fibroblast growth factor in mouse models of H(22) hepatocellular carcinoma.
Abstract OBJECTIVE: To investigate the efficacy of Ciji Hua'ai Baosheng formula (CHBF) on microvessel density (MVD) and vascular endothelial growth factor (VEGF), kinase insert domain-containing receptor (KDR) and basic fibroblast growth factor (bFGF) expression in serum and tumor tissue of mice receiving chemotherapy for the treatment of H(22) hepatocellular carcinoma. METHODS: Sixty Kunming mice were injected subcutaneously with H(22) hepatoma carcinoma cell suspensions into the right anterior armpit. Seven days later, all transplanted tumor were formed and the mice were intraperitoneally injected 200 mg/kg...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Zhao X, Xi S, Wang Y, Xu Y, Pollock G, Su Y, Cheng Y, Loy G, Liu P Tags: J Tradit Chin Med Source Type: research

Effects of electroacupuncture at Guanyuan (CV 4) or Sanyinjiao (SP 6) on hypothalamus-pituitary-ovary axis and spatial learning and memory in female SAMP8 mice.
Abstract OBJECTIVE: To investigate the effects of electroacupuncture (EA) at the Guanyuan (CV 4) or Sanyinjiao (SP 6) acupoints on the hypothalamus-pituitary-ovary (HPO) axis and spatial learning and memory in female mice. METHODS: Nine-month-old female mice with senescence-accelerated mouse prone 8 (SAMP8) were divided into three groups: the disease model, EA-Guanyuan and EA-Sanyinjiao groups. Concurrently, 9-month old female mice with senescence-accelerated mouse resistance 1 (SAMR1) were set as the control model group. The two treatment groups were given the same pattern of EA stimulation. Gonadotropin-rel...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Wang J, Cheng K, Qin Z, Wang Y, Zhai L, You M, Wu J Tags: J Tradit Chin Med Source Type: research

Serum from asthmatic rat treated with acupuncture inhibits acetylcholine- induced contractile responses of airway smooth muscle cells.
Abstract OBJECTIVE: To investigate the influence of serum from asthmatic rat treated with acupuncture (acupuncture serum) on the contractile responses of airway smooth muscle cells (ASMCs). METHODS: OVA-induced asthmatic rats were subject to acupuncture treatment at the points of Dazhui (GV 14), Fengmen (BL 12), and Feishu (BL 13). The resulting serum was collected, as well as serum from normal animals. Contraction of ASMCs was induced with 10 μM acetylcholine (Ach), and acupuncture serum or normal serum was supplemented 15 min later. The effects of the sera on the changes in cell length, width, and surfac...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Xu Y, Yin L, Park GH, Wang Y, Wang W, Liu Y, Yang Y Tags: J Tradit Chin Med Source Type: research

Microvascular pathological features and changes in related injury factors in a rat acute blood stasis model.
CONCLUSION: The pathological manifestations of acute blood stasis are microvascular blood retention, lumen stenosis and even occlusion. The condition is also called "blood coagulation and weep" in Traditional Chinese Medicine. The blood stasis model resulted in the injury and necrosis of endothelial cells and cardiomyocytes, along with the presence of an imbalance of vasomotor factor levels, platelet activation, and increases in the expression of adhesion molecules and endothelial barrier dysfunction, which corresponds to "blood failed to nourish" in Traditional Chinese Medicine. PMID: 29957919 [Pu...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Zhang J, Feng Y, Li S, Liu Y, Zhang Y, Guo Y, Yang M Tags: J Tradit Chin Med Source Type: research

Mechanism studies of Xinfeng capsule on improving cardiovascular function though toll-like receptor 4/nuclear factor kappa B pathway in a rat model of adjuvant arthritis.
Abstract OBJECTIVE: To observe the impact of Xinfeng capsule (XFC) on cardiovascular function in adjuvant arthritis (AA) model rats and investigate the mechanism though toll-like receptor 4 (TLR4)/nuclear factor kappa B (NF-κB) signaling pathway. METHODS: Seventy rats were randomly divided into seven groups: normal control (NC), model control (MC), tripterygium glycosides tablet (TPT), methotrexate (MTX), high, moderate and low dose XFC group. The administration began from day 19 after modeling for 30 day. Paw swelling, arthritic index (AI), cardiac function indexes and myocardial pathological pattern w...
Source: Journal of Traditional Chinese Medicine - February 1, 2017 Category: Complementary Medicine Authors: Wang Y, Liu J, Huang C, Sun Y, Zhang W, Wan L, Zong R, Wang Y Tags: J Tradit Chin Med Source Type: research

[Clinical value of Tongguanteng (Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy in the treatment of advanced non-small cell lung cancer: a Meta-analysis].
CONCLUSION: This Meta-analysis suggests that Tongguanteng (Radix seu Herba Marsdeniae Tenacissimae) extract combined with chemotherapy may be more efficacious in the treatment of advanced NSCLC than chemotherapy alone. This effect includes enhancing ER and QOLIR, and weakening chemotherapy toxicity. However, large-scale RCTs are required to further investigate the short- and long-term effects of Tongguanteng (Radix seu Herba Marsdeniae Tenacissimae) extract. PMID: 27468539 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Zhang H, Zhang J, Ding H, Chen R, Liang F Tags: J Tradit Chin Med Source Type: research

[Effectiveness of acupuncture in postoperative ileus: a systematic review and Meta-analysis].
CONCLUSION: The results suggested that acupuncture might be effective in improving POI; however, a definite conclusion could not be drawn because of the low quality of trials. Further large-scale, high-quality randomized clinical trials are needed to validate these findings and to develop a standardized method of treatment. We hope that the present results will lead to improved research, resulting in better patient care worldwide. PMID: 27468540 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Cheong KB, Zhang J, Huang Y Tags: J Tradit Chin Med Source Type: research

[Multicenter clinical efficacy observation of integrated Traditional Chinese Medicine-Western Medicine treatment in acute onset period of pulmonary heart disease].
CONCLUSION: Comprehensive integrated TCM-WM treatment showed good clinical efficacy toward the acute onset period of PHD patients. PMID: 27468541 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Lu Y, Jin W, Zhang H, Zhang X Tags: J Tradit Chin Med Source Type: research

[Effect of Qingxue Dan on obesity and metabolic biomarker: a double-blind randomized-controlled pilot study].
CONCLUSION: 8-weeks of oral administrations of QXD (900 mg/d) reduces BMI, with a tendency of lose of total body fat mass, especially abdominal fat. It also significantly reduced serum TG level. These results suggest QXD could be used to treat obesity and metabolic risk factors. Further study is needed to confirm our pilot findings. PMID: 27468542 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Chung W, Ryu J, Chung S, Kim S Tags: J Tradit Chin Med Source Type: research

[Effect of Astragali and Angelica particle on proteinuria in Chinese patients with primary glomerulonephritis].
Abstract OBJECTIVE: To investigate the effect of the traditional Chinese herbs Astragali and Angelicae Sinensis (A & As) particle [contains Huangqi (Radix Astragali Mongolica), Danggui (Radix Angelicae Sinensis), Huzhanggeng (Rhizoma Polygoni Cuspidati) and Danshen (Radix Salviae Miltiorrhizae)] on proteinuria in glomerulonephritis patients with stage 2 chronic kidney disease. METHODS: A prospective, multi-center, and randomized controlled clinical trial was performed for 24 weeks. From March 2011 to April 2012, 158 patients from nine hospitals in China participated. They were randomized into the A & ...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Shen P, Yang X, He L Tags: J Tradit Chin Med Source Type: research

[Retrospective study of Traditional Chinese Medicine treatment of type 2 diabetes mellitus].
Abstract OBJECTIVE: To provide clinical evidence in support of Dahuang Huanglian Xiexin decoction (DHXD) to treat type 2 diabetes mellitus (T2DM) and to introduce a new treatment option for clinicians. METHODS: Retrospective analysis was used to evaluate DHXD for the treatment of T2DM by analyzing clinical records of 183 cases. Patients with T2DM who met the inclusion criteria between January 1, 2013 and January 1, 2014 were enrolled. The effects of the treatment were evaluated by the changes in fasting blood-glucose (FBG), postprandial blood sugar (PBG), hemoglobin A1c (HbA1c), blood lipid profiles and body ...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Pang B, Guo J, Zhao L, Zhao X, Zhou Q, Tong X Tags: J Tradit Chin Med Source Type: research

[Effect of Chinese massage (Tui Na) on isokinetic muscle strength in patients with knee osteoarthritis].
Abstract OBJECTIVE: Chinese massage (Tui Na) is one of the most popular Traditional Chinese Medicine remedies for knee osteoarthritis (OA). Several studies have subjectively evaluated the effect of Chinese massage on knee OA through self-assessment questionnaires; however, very few studies have objectively assessed the effect by measuring knee muscle strength. The purpose of this study was to assess the efficacy of Chinese massage in improving knee extensor and flexor muscle strength in patients with knee OA. METHODS: Thirty patients with knee OA received Chinese massage therapy three times per week for 2 wee...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Zhu Q, Li J, Fang M, Gong L, Sun W, Zhou N Tags: J Tradit Chin Med Source Type: research

[Purple-bluish tongue is associated with platelet counts, and the recurrence of epithelial ovarian cancer].
Abstract OBJECTIVE: To evaluate the relationship between purple-bluish tongue and platelet counts, and further to examine their associations with the recurrence of epithelial ovarian cancer. METHODS: A total of 82 epithelial ovarian cancer patients were enrolled in this study. Cluster analysis was used for grouping patients' P(RGB) (Red-R; Green-G; Blue-B; Average percentage of RGB, P(RGB)) values. Receiver operating characteristic (ROC) curve was performed for detecting the diagnostic standard of purple-bluish tongue. Χ2 test was used to assess the relationship between purple-bluish tongue and platelet c...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Hao J, Zhu C, Cao R, Yang X, Ding X, Man Y, Wu X Tags: J Tradit Chin Med Source Type: research

[Changes in symptom patterns and health-related quality of life of cancer patients before and after chemotherapy].
This study aimed to describe the changes in the pattern of symptoms of Yang-deficiency, Yin-deficiency, blood stasis, and HRQOL before and after chemotherapy, and to examine the association between the patterns and the cancer patients' HRQOL. METHODS: A panel study was undertaken with 123 cancer patients who were about to begin their first course of chemotherapy at four teaching hospitals in Taiwan. A structured questionnaire was used before and after chemotherapy. HRQOL was assessed using the Medical Outcomes Survey Short-Form 36. The Traditional Chinese Medical Constitutional Scale was used to measure Yang-deficienc...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Chung HW, Chien LY, Huang SM, Tai CJ, Tai CJ Tags: J Tradit Chin Med Source Type: research

[Algal oligosaccharides ameliorate osteoporosis via up-regulation of parathyroid hormone 1-84 and vascular endothelial growth factor].
Abstract OBJECTIVE: To determine whether algal oligosac- charide~ affects the levels of parathyroid hormone 1-84 (PTH1-84) and vascular endothelial growth fac- tor (VEGF). METHODS: An osteoporosis rat model was estab- lished via bilateral ovariectomy. The model rats were fed algal oligosaccharides (molecular weights: 600-1, 200 Da) for 4 months. Bone mineral density (BMD) was then measured. MG-63 human osteo- blastic cells were treated with algal oligosaccha- rides. The expression of PTH1-84 and VEGF was then examined. Oligosaccharide-treated cells were transfected with PTH1-84 short hairpin RNA (shR- NA), VE...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Wang L, Wang H, Fang N Tags: J Tradit Chin Med Source Type: research

[Effect of moxa-burning heat stimulating Liangmen (ST 21) and Zusanli (ST 36) on proliferation and apoptosis signaling proteins in rats with stress-induced gastric ulcer].
Abstract OBJECTIVE: To observe the effect of moxa-burning heat stimulating acupoints of Liangmen (ST 21) and Zusanli (ST 36) on the proliferation and apoptosis signaling proteins in rats with stress-induced gastric ulcer. METHODS: Forty rats were randomly divided into four groups: negative control (NC), ulcer control (UC), acupoints of stomach meridian (ASM), and acupoints control (AC). The acute gastric ulcer model was established by bound and water immersion. Rats in NC and UC groups didn't receive any moxa-burning heat stimulating treatment, while rats in ASM and AC groups were treated with buringmoxa heat...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Peng L, Wang Y, Chang X, Wu H, Liu M, Wang H, Chen J, Wang Chao, Quan R, Yang Z Tags: J Tradit Chin Med Source Type: research

[Chinese herbal medicine enhances sexual function and c-Fos/nNOS expression in the nucleus accumbens of orchidectomized rats].
CONCLUSION: An increase of plasma testosterone after administration of "kidney-nourishing" herbal medicine might contribute to the elevated sexual function and activity in orchidectomized rats. In addition, a central nervous system mechanism, such as the functional alteration of NAc, might be involved. Abstract OBJECTIVE: To determine whether the central nervous system is involved in the effect of Chinese herbal medicine on sexual function recovery in orchidectomized rats. METHODS: Orchidectomized rats were administered intragastrically with a decoction of "kidney-nourishing" Chinese herbal me...
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Liu H, Cui J, Zhai H, Xue J, Wang X Tags: J Tradit Chin Med Source Type: research

[Evodiamine induces extrinsic and intrinsic apoptosis of ovarian cancer cells via the mitogen-activated protein kinase/phosphatidylinositol-3-kinase/protein kinase B signaling pathways].
CONCLUSION: Evodiamine can inhibit the growth of ovarian cancer cells by G2/M arrest and intrinsic and extrinsic apoptosis. In addition, evodiamine-induced PI3K/Akt, ERK1/2 MAPK, and p38 MAPK signaling may be involved in cell death. PMID: 27468551 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Wei L, Jin X, Cao Z, Li W Tags: J Tradit Chin Med Source Type: research

[Wnt/ β-catenin signaling is involved in the Icariin induced proliferation of bone marrow mesenchymal stem cells].
CONCLUSION: The findings of the present study demonstrated that low dosage of icariin could promote BMSCs proliferation. The activation of Wnt/β-catenin pathways was involved in this process. PMID: 27468552 [PubMed - in process] (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - June 1, 2016 Category: Complementary Medicine Authors: Fu S, Yang L, Hong H, Zhang R Tags: J Tradit Chin Med Source Type: research