Journal of Traditional Chinese Medicine 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials
CONCLUSION: The current Meta-analysis revealed that HQ-based TCM yields higher efficacy and safety than Western Medicine alone for the treatment of DPN, although further well-designed RCTs are required to validate these findings.PMID:38504529 | PMC:PMC10927399 | DOI:10.19852/j.cnki.jtcm.2024.02.004 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Ping Jing Hao Hongzheng W U Zhenqi Zou Meijuan L I Zuojing Cheng Gang Source Type: research
Efficacy and safety of extracorporeal shock wave therapy combined with sodium hyaluronate in treatment of knee osteoarthritis: a systematic review and Meta-analysis
CONCLUSIONS: Medium to low quality evidence showed that ESWT combined with HA offers an inexpensive, well-tolerated, safe, and effective method to improve pain and functionality in patients with KOA. However, tightly controlled, randomized, large multicenter trials are warranted to validate the current findings.PMID:38504530 | PMC:PMC10927402 | DOI:10.19852/j.cnki.jtcm.20231226.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zhou Mingwang Dong Zhuanli Wei Changhao Feng Lufang Wang Xiaoping Liu Haiping J I Xing Yang Kehu L I Shenghua Source Type: research
Polyphyllin I enhances tumor necrosis factor-related apoptosis-inducing ligand-induced inhibition of human osteosarcoma cell growth downregulating the Wnt/ β-catenin pathway
CONCLUSION: The combination of PPI and TRAIL is potentially a novel treatment strategy of osteosarcoma.PMID:38504531 | PMC:PMC10927409 | DOI:10.19852/j.cnki.jtcm.2024.02.002 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Chang Junli Zhao Fulai Sun Xingyuan M A Xiaoping Zhao Peng Zhou Chujie Shi Binhao G U Wenchao Wang Yongjun Yang Yanping Source Type: research
Anti-inflammatory mechanism of the non-volatile ingredients originated from Guanghuoxiang () based on high performance liquid chromatography-heated electron spray ionization-high resolution mass spectroscope and cell metabolomics
CONCLUSION: The non-volatile ingredients of patchouli had good anti-inflammatory effect and exerted its curative effect by regulating endogenous metabolic pathway to reduce inflammatory response.PMID:38504532 | PMC:PMC10927411 | DOI:10.19852/j.cnki.jtcm.20240203.003 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Jing Wenguang Lin Xiaoyu L I Chu Zhao Xiaoliang Cheng Xianlong Wang Penglong Wei Feng M A Shuangcheng Source Type: research
Emodin suppresses alkali burn-induced corneal inflammation and neovascularization by the vascular endothelial growth factor receptor 2 signaling pathway
CONCLUSION: This study provides a new avenue for evaluating the molecular mechanisms underlying corneal inflammation and neovascularization. Emodin might be a promising new therapeutic option for corneal alkali burns.PMID:38504533 | PMC:PMC10927407 | DOI:10.19852/j.cnki.jtcm.20240203.005 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zheng Xueying Guo Liang Lai Siyi L I Fengyue Liang Mingli Liu Wanting Meng Chun Liu Guanghui Source Type: research
Gehua Jiejiu Dizhi decoction ameliorates alcoholic fatty liver in mice by regulating lipid and bile acid metabolism and with exertion of antioxidant stress based on 4DLabel-free quantitative proteomic study
CONCLUSIONS: Our study provided proteomics-based evidence that GJDD alleviated AFLD by modulating liver protein expression, likely through the modulation of lipid metabolism, bile acid metabolism and with exertion of antioxidant stress.PMID:38504534 | PMC:PMC10927405 | DOI:10.19852/j.cnki.jtcm.20231018.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Han Min Y I Xu You Shaowei W U Xueli Wang Shuoshi H E Diancheng Source Type: research
Efficacy of Sailuotong on neurovascular unit in amyloid precursor protein/presenilin-1 transgenic mice with Alzheimer's disease
CONCLUSIONS: By increasing the expression of VEGF, SLT can promote vascular proliferation, up-regulate the expression of LRP-1, promote the clearance of Aβ and improve the cognitive impairment of APP/PS1 mice. These results confirm that SLT can improve AD by promoting vascular proliferation and Aβ clearance to protect the function of NVUs.PMID:38504535 | PMC:PMC10927413 | DOI:10.19852/j.cnki.jtcm.20240203.007 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Sun Linjuan L I Chengfu Liu Jiangang L I Nannan Han Fuhua Qiao Dandan Tao Zhuang Zhan Min Chen Wenjie Zhang Xiaohui Tong Chenguang Chen Dong Qi Jiangxia Liu Yang Liang Xiao Zheng Xiaoying Zhang Yunling Source Type: research
Yemazhui () ameliorates lipopolysaccharide-induced acute lung injury modulation of the toll-like receptor 4/nuclear factor kappa-B/nod-like receptor family pyrin domain-containing 3 protein signaling pathway and intestinal flora in rats
CONCLUSIONS: In summary, our findings revealed that HEL has a protective effect on LPS-induced ALI in rats, and its mechanism may be related to inhibiting TLR4/ NF-κB/NLRP3 signaling pathway and improving intestinal flora disturbance.PMID:38504536 | PMC:PMC10927412 | DOI:10.19852/j.cnki.jtcm.20230510.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Ren Li Hai Yang Yang Xue Luo Xianqin Source Type: research
Protective effect of thyroid and restores of ovarian function of Buzhong Yiqi granule on experimental autoimmune thyroiditis in female rats
CONCLUSIONS: BZYQ granule could regulate the thyroid function of EAT rats, reduce thyroid antibody titers, then act on the ovarian function, regulate hormone disorders, and alleviate the pathological damage of rat's ovarian tissues. The effect of high dose Buzhong Yiqi granule is the best.PMID:38504537 | PMC:PMC10927403 | DOI:10.19852/j.cnki.jtcm.20240203.008 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Wang Yuezhu Zhang Yuyang Qiao Jiajun L U Yuyuan Xia Zhongyuan Source Type: research
Protective effect of modified Huangqi Chifeng decoction on immunoglobulin A nephropathy through toll-like receptor 4/myeloid differentiation factor 88/nuclear factor-kappa B signaling pathway
CONCLUSIONS: MHCD exerted nephroprotective effects on IgAN rats, and MHCD regulated the expressions of key targets in TLR4/MyD88/NF-κB signaling pathway, thereby alleviating renal inflammation by inhibiting MCP-1, IL-6 expressions, and ameliorating renal fibrosis by inhibiting TGF-β1 expression.PMID:38504538 | PMC:PMC10927408 | DOI:10.19852/j.cnki.jtcm.20240203.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: L I Liusheng Zhao Mingming Chang Meiying S I Yuan Zhao Jinning Yang Bin Zhang Yu Source Type: research
Mechanisms of Dangua Fang in multi-target and multi-method regulation of glycolipid metabolism based on phosphoproteomics
CONCLUSION: DGR extensively corrects the modification of phosphorylation sites to improve corresponding glycolipid metabolism-related protein expression in rats with glycolipid metabolism disorders, thereby regulating glycolipid metabolism through a multi-target and multi-method process.PMID:38504539 | PMC:PMC10927395 | DOI:10.19852/j.cnki.jtcm.20230908.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Heng Xianpei Wang Zhita L I Liang Yang Liuqing Huang Suping Jin Lang H E Weidong Source Type: research
Mechanism of acupuncture in attenuating cerebral ischaemia-reperfusion injury based on nuclear receptor coactivator 4 mediated ferritinophagy
CONCLUSIONS: Acupuncture can inhibit NCOA4-mediated ferritinophagy and protect neurons against CIRI in a rat model.PMID:38504540 | PMC:PMC10927404 | DOI:10.19852/j.cnki.jtcm.20240203.006 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zhang Xinchang Huang Zheng Huang Peiyan Yang Mengning Zhang Zhihui N I Guangxia Source Type: research
Moxibustion of Zusanli (ST36) and Shenshu (BL23) alleviates the inflammation of rheumatoid arthritis in rats through regulating macrophage migration inhibitory factor/glucocorticoids signaling
CONCLUSION: Reducing MIF to increase CORT and decrease TNF-α by moxibustion treatment in RA. MIF may be a factor for moxibustion to regulate the expression of CORT, but the expression of TNF-α is due to the incomplete regulation of the MIF. This study added to the body of evidence pointing to moxibustion's anti-inflammatory mechanism in the treatment of RA.PMID:38504541 | PMC:PMC10927400 | DOI:10.19852/j.cnki.jtcm.20220602.001 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Zhang Linlin Zhong Yumei L U Wenting Shang Yanan Guo Yanding Luo Xiaochao Chen Yang Luo Kun H U Danhui Y U Huiling Zhou Haiyan Source Type: research
Network pharmacology and experimental validation to reveal the pharmacological mechanisms of Sini decoction against renal fibrosis
J Tradit Chin Med. 2024 Apr;44(2):362-372. doi: 10.19852/j.cnki.jtcm.20230630.003.ABSTRACTOBJECTIVE: To investigate the mechanism by which Sini decoction (, SND) improves renal fibrosis (Rf) in rats based on transforming growth factor β1/Smad (TGF-β1/Smad) signaling pathway.METHODS: Network pharmacology was applied to obtain potentially involved signaling pathways in SND's improving effects on Rf. The targets of SND drug components and the targets of Rf were obtained by searching databases, such as the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCSMP) and GeenCard. The intersection ...
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: Wang Yan Deng Fanying Liu Shiqi Wang Yingli Source Type: research
Effectiveness and safety of Jiawei Xiaoyao pill in the treatment of premenstrual syndrome (liver depression, spleen deficiency, and blood-heat syndrome): a multi-center, randomized, placebo-controlled trial
CONCLUSIONS: JXP was superior to the placebo in relieving the symptoms associated with PMS, which signified that JXP may be effective, safe, and well-tolerated as an alternative therapy.PMID:38504543 | PMC:PMC10927397 | DOI:10.19852/j.cnki.jtcm.20231110.003 (Source: Journal of Traditional Chinese Medicine)
Source: Journal of Traditional Chinese Medicine - March 20, 2024 Category: Complementary Medicine Authors: L I Xiyu Yang Yanhong Sun Jian Nie Quanfang Liu Lifen L I Guifen Y U Junping Zhang Zhuangjin X U Yi Zou Ting Shi Yun Source Type: research
