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Drug: Melatonin
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Total 4647 results found since Jan 2013.
Melatonin: A look at protozoal and helminths
Biochimie. 2023 Aug 2:S0300-9084(23)00182-7. doi: 10.1016/j.biochi.2023.07.021. Online ahead of print.ABSTRACTMelatonin is a pleiotropic neurohormone found in different animal, plant, and microorganism species. It is a product resulting from tryptophan metabolism in the pineal gland and is widely known for its ability to synchronize the circadian rhythm to antitumor functions in different types of cancers. The molecular mechanisms responsible for its immunomodulatory, antioxidant and cytoprotective effects involve binding to high-affinity G protein-coupled receptors and interactions with intracellular targets that modulate...
Source: Biochimie - August 4, 2023 Category: Biochemistry Authors: Pablo Igor Ribeiro Franco Jos é Rodrigues do Carmo Neto Rhanoica Oliveira Guerra Priscilla Elias Ferreira da Silva Yarlla Loyane Lira Braga Mara R úbia Nunes Celes Liliana Borges de Menezes Marina Pacheco Miguel Juliana Reis Machado Source Type: research
The cutaneous stress response system in three-spined stickleback and European flounder exposed to oxidative stress: Different mode of action
This study investigates the mode of action of CSRS in two teleost species of different biology and skin characteristics, the three-spined stickleback and the European flounder, after exposure to oxidative stress induced by a potassium dichromate solution. The cutaneous stress response system presents different ways of action in two studied species: Mel concentration increases in the skin of both species, but cortisol concentration increases in the skin only in sticklebacks. Data suggest that stickleback skin cells can produce cortisol. However, cortisol is not involved in the response to oxidative stress in flounders. In s...
Source: Comparative Biochemistry and Physiology. Part A, Molecular and integrative physiology. - August 4, 2023 Category: Physiology Authors: Konrad Pomianowski Magdalena Gozdowska Ewa Soko łowska Ewa Kulczykowska Source Type: research
Melatonin: A look at protozoal and helminths
Biochimie. 2023 Aug 2:S0300-9084(23)00182-7. doi: 10.1016/j.biochi.2023.07.021. Online ahead of print.ABSTRACTMelatonin is a pleiotropic neurohormone found in different animal, plant, and microorganism species. It is a product resulting from tryptophan metabolism in the pineal gland and is widely known for its ability to synchronize the circadian rhythm to antitumor functions in different types of cancers. The molecular mechanisms responsible for its immunomodulatory, antioxidant and cytoprotective effects involve binding to high-affinity G protein-coupled receptors and interactions with intracellular targets that modulate...
Source: Biochimie - August 4, 2023 Category: Biochemistry Authors: Pablo Igor Ribeiro Franco Jos é Rodrigues do Carmo Neto Rhanoica Oliveira Guerra Priscilla Elias Ferreira da Silva Yarlla Loyane Lira Braga Mara R úbia Nunes Celes Liliana Borges de Menezes Marina Pacheco Miguel Juliana Reis Machado Source Type: research
High AIECL performance of tetraphenylethene derivatives originated from the linear increasing of benzene ring and solvent regulation for sensitive measurement of melatonin
Biosens Bioelectron. 2023 Jul 27;237:115544. doi: 10.1016/j.bios.2023.115544. Online ahead of print.ABSTRACTThe efficiency of aggregation-induced electrochemiluminescence (AIECL) in tetraphenylethene (TPE) derivatives were significantly enhanced by combining the regulation of molecular structure and solvent. Firstly, the linear increase of the benzene ring resulted in enhanced molecular aggregation and promoted the electrochemical reaction of the anode, due to increased molecular conjugation and higher lowest unoccupied molecular orbital (LUMO) and highest occupied molecular orbital (HOMO). The ECL efficiency of 4,4,4,4-(E...
Source: Biosensors and Bioelectronics - August 3, 2023 Category: Biotechnology Authors: Zhen Wang Weiwei Cao Ruo Yuan Haijun Wang Source Type: research
An amorphous zinc/copper double transition metal hydroxides for electrochemical simultaneous detection of dopamine, serotonin and melatonin
New J. Chem., 2023, Accepted Manuscript DOI: 10.1039/D3NJ02297H, PaperShanshan Tang, Miao Liu, wei wang, Axin Liang, Fulai Zhang, Aiqin Luo A novel electrochemical sensor, whose working electrode was a glassy carbon electrode modified with amorphous zinc/copper double transition metal hydroxides(ZnCu-TMH/GCE), was developed for simultaneous detection of dopamine(DA), serotonin(5-HT) and melatonin(MT),... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - New J. Chem. latest articles - August 1, 2023 Category: Chemistry Authors: Shanshan Tang Source Type: research
Complementary and alternative treatments for insomnia disorder: a systematic umbrella review
J Sleep Res. 2023 Aug 1:e13979. doi: 10.1111/jsr.13979. Online ahead of print.ABSTRACTInsomnia is a common disorder and cognitive behavioural therapy for insomnia (CBT-I) is recommended as first-line treatment. However, CBT-I is not widely distributed and infrequently available while medication is not indicated for long-term use. To close this evident gap in supply, alternative treatments could be utilised. High-quality research on this topic is scarce, and there is currently no comprehensive publication on the effectiveness of alternative treatments. To address this pressing question, we systematically summarised the exis...
Source: Journal of Sleep Research - August 1, 2023 Category: Sleep Medicine Authors: Johanna Ell Sarah R Schmid Fee Benz Lukas Spille Source Type: research
Protective effect of exogenous melatonin on testicular histopathology and histomorphometry of adult rats with domperidone-induced hyperprolactinemia
In conclusion, the hyperprolactinemia can affect the germinal epithelium and testicular microstructure; the exogenous melatonin has a protective effect against hyperprolactinemia, reducing testicular damage.PMID:37517145 | DOI:10.1016/j.repbio.2023.100791
Source: Reproductive Biology - July 30, 2023 Category: Reproduction Medicine Authors: Ewerton Fylipe de Ara újo Silva Jos é Anderson da Silva Gomes Maria Lu ísa Figueira de Oliveira Arthur Gabriel Alves Furtado de Carvalho Noya Carolina Peixoto Magalh ães Jo ão Vitor da Silva Luiz Henrique da Silva Bruno Mendes Tenorio Marcelo Moraes Source Type: research
Pharmacotherapy and Nutritional Supplements for Neovascular Eye Diseases
Medicina (Kaunas). 2023 Jul 20;59(7):1334. doi: 10.3390/medicina59071334.ABSTRACTIn this review, we aim to provide an overview of the recent findings about the treatment of neovascular retinal diseases. The use of conventional drugs and nutraceuticals endowed with antioxidant and anti-inflammatory properties that may support conventional therapies will be considered, with the final aim of achieving risk reduction (prevention) and outcome improvement (cooperation between treatments) of such sight-threatening proliferative retinopathies. For this purpose, we consider a medicinal product one that contains well-defined compoun...
Source: Medicina (Kaunas) - July 29, 2023 Category: Universities & Medical Training Authors: Dario Rusciano Paola Bagnoli Source Type: research
