Ambulatory detection of sleep apnea using a non-contact biomotion sensor.
Abstract The high prevalence of obstructive sleep apnea has led to increasing interest in ambulatory diagnosis. The SleepMinder™ (SM) is a novel non-contact device that employs radiofrequency wave technology to assess the breathing pattern, and thereby estimate obstructive sleep apnea severity. We assessed the performance of SleepMinder™ in the home diagnosis of obstructive sleep apnea. One-hundred and twenty-two subjects were prospectively recruited in two protocols, one from an unselected sleep clinic cohort (n = 67, mean age 51 years) and a second from a hypertension clinic cohort (n&...
Source: Journal of Sleep Research - June 30, 2019 Category: Sleep Medicine Authors: Crinion SJ, Tiron R, Lyon G, Zaffaroni A, Kilroy H, Doheny E, O'Hare E, Boyle P, Russell A, Traynor M, Kent BD, Ryan S, McNicholas WT Tags: J Sleep Res Source Type: research

Symptom-related changes in current perception threshold of restless legs syndrome.
The objective of this study was to investigate the function of sensory nerve fibres in RLS patients using the current perception threshold (CPT) test during the daytime and in the presence of symptoms. Ninety-three patients with RLS and 34 healthy controls were included in the study. RLS patients were further divided into two subgroups, those who were experiencing RLS symptoms during the CPT test (symptom+) and those without symptoms (symptom-). Demographic data, RLS rating scale score and visual analogue scale were collected. Of the 127 enrolled subjects, CPT values were significantly lower in RLS patients than in control...
Source: Journal of Sleep Research - June 25, 2019 Category: Sleep Medicine Authors: Seok HY, Do SY, Motamedi GK, Cho YW Tags: J Sleep Res Source Type: research

Sleep deprivation increases threat beliefs in human fear conditioning.
Abstract Sleep disturbances and anxiety disorders exhibit high comorbidity levels, but it remains unclear whether sleep problems are causes or consequences of increased anxiety. To experimentally probe the aetiological role of sleep disturbances in anxiety, we investigated in healthy participants how total sleep deprivation influences fear expression in a conditioning paradigm. In a fear conditioning procedure, one face stimulus (conditioned stimulus [CS+]) was paired with electric shock, whereas another face stimulus was not (unpaired stimulus [CS-]). Fear expression was tested the next morning using the two face...
Source: Journal of Sleep Research - June 17, 2019 Category: Sleep Medicine Authors: Zenses AK, Lenaert B, Peigneux P, Beckers T, Boddez Y Tags: J Sleep Res Source Type: research

Cardiac autonomic dynamics during sleep are lost in patients with TIA and stroke.
Abstract Ischaemic stroke is accompanied by important alterations of cardiac autonomic control, which have an impact on stroke outcome. In sleep, cardiac autonomic control oscillates with a predominant sympathetic modulation during REM sleep. We aimed to assess cardiac autonomic control in different sleep stages in patients with ischaemic stroke. Forty-five patients enrolled in the prospective, multicentre SAS-CARE study but without significant sleep-disordered breathing (apnea-hypopnea index 
Source: Journal of Sleep Research - June 13, 2019 Category: Sleep Medicine Authors: Tobaldini E, Proserpio P, Oppo V, Figorilli M, Fiorelli EM, Manconi M, Agostoni EC, Nobili L, Montano N, Horvath T, Bassetti CL Tags: J Sleep Res Source Type: research

An open-ended primary-care group intervention for insomnia based on a self-help book - A randomized controlled trial and 4-year follow-up.
v S Abstract Chronic insomnia is a common and burdensome problem for patients seeking primary care. Cognitive behavioural therapy has been shown to be effective for insomnia, also when presented with co-morbidities, but access to sleep therapists is limited. Group-treatment and self-administered treatment via self-help books have both been shown to be efficacious treatment options, and the present study aimed to evaluate the effect of an open-ended group intervention based on a self-help book for insomnia, adapted to fit a primary-care setting. Forty primary-care patients with insomnia (mean age 55 years, 8...
Source: Journal of Sleep Research - June 11, 2019 Category: Sleep Medicine Authors: Kaldo V, Bothelius K, Blom K, Lindhe M, Larsson M, Karimi K, Melder S, Bondestam V, Ulfsparre C, Sternbrink K, Jernelöv S Tags: J Sleep Res Source Type: research

Obstructive sleep apnea is associated with worse clinical-radiological risk scores of pulmonary embolism.
Soriano JB, Calvo N, Pinilla I, García-Río F Abstract Obstructive sleep apnea is a risk factor for pulmonary embolism, although its association with pulmonary embolism severity is unknown. Our objective was to study if obstructive sleep apnea is associated with worse pulmonary embolism severity scores and greater extent of arterial obstruction. In consecutive pulmonary embolism patients, we performed respiratory polygraphy and recorded sleep characteristics, classical risk factors for pulmonary embolism and physical activity 6-12 months after the pulmonary embolism episode. Simplified Geneva Pr...
Source: Journal of Sleep Research - June 10, 2019 Category: Sleep Medicine Authors: Toledo-Pons N, Alonso-Fernández A, de la Peña M, Pierola J, Barceló A, Fernández-Capitán C, Lorenzo A, Mejía Núñez JA, Carrera M, Soriano JB, Calvo N, Pinilla I, García-Río F Tags: J Sleep Res Source Type: research

Microsleep as a marker of sleepiness in obstructive sleep apnea patients.
Abstract We hypothesized that: (a) the presence of microsleep (MS) during a Maintenance Wakefulness Test (MWT) trial may represent a reliable marker of sleepiness in obstructive sleep apnea (OSA) patients; (b) the number of MSs will be higher in sleepy versus non-sleepy patients with a borderline MWT mean sleep latency; and (c) scoring MS during MWT analysis may help physicians to recognize patients with a higher degree of sleepiness. We analysed the MWT data of 112 treatment-naïve OSA patients: 20 with short sleep latency (SL, sleep latency 32.6 min). Microsleep was identified in all SL, in 42 BL and in...
Source: Journal of Sleep Research - June 10, 2019 Category: Sleep Medicine Authors: Morrone E, D'Artavilla Lupo N, Trentin R, Pizza F, Risi I, Arcovio S, Fanfulla F Tags: J Sleep Res Source Type: research

Psychometric properties and cultural adaptation of sleep disturbance measures in Arabic-speaking populations: A systematic review.
Abstract The aim of this review was to evaluate the psychometric properties and cross-cultural adaptation of sleep disturbance scales that have been translated into Arabic or originally developed in Arabic, and to identify appropriate scales that can be used in research and clinical practice intended for Arabic-speaking participants. The following databases were searched: CINAHL (2003-2019), MEDLINE (1946-2019), EMBASE (1980-2019), PsycINFO (1806-2019) and Cochrane Library (1806-2019). This review was conducted following PRISMA guidelines. Terwee et al. (J. Clin. Epidemiol., 60, 2007, 34) quality assessment w...
Source: Journal of Sleep Research - June 10, 2019 Category: Sleep Medicine Authors: Al Maqbali M, Dunwoody L, Rankin J, Hacker E, Hughes C, Gracey J Tags: J Sleep Res Source Type: research

The effects of sleep extension on cardiometabolic risk factors: A systematic review.
Abstract Studies have shown bidirectional relationships between short- or long-sleep duration and risk for obesity, non-communicable diseases, all-cause mortality and cardiovascular disease mortality. Increasing sleep duration may be an appropriate strategy to reduce cardiometabolic risk in short-sleeping individuals. The aim is to review the effects of sleep extension interventions on cardiometabolic risk in adults. The PubMed and Scopus databases were searched for relevant, English, peer-reviewed scientific publications (until August 2018). Seven studies that aimed to increase sleep duration in adults by any sle...
Source: Journal of Sleep Research - June 5, 2019 Category: Sleep Medicine Authors: Henst RHP, Pienaar PR, Roden LC, Rae DE Tags: J Sleep Res Source Type: research

Gender differences in clinical, laboratory and polysomnographic features of restless legs syndrome.
This study aims to evaluate gender differences in clinical, laboratory and polysomnographic features in patients with restless legs syndrome. For this retrospective analysis, 42 women and 42 men from the Innsbruck RLS database matched by age and therapy were included. Demographic data as well as different severity scales (IRLS, RLS-6 and CGI) were evaluated. Laboratory parameters included several indicators of serum iron status. In all patients, polysomnography was performed according to the AASM guidelines, and periodic leg movements during sleep were scored according to the AASM criteria. IRLS, RLS-6 and CGI revealed mor...
Source: Journal of Sleep Research - June 4, 2019 Category: Sleep Medicine Authors: Holzknecht E, Hochleitner M, Wenning GK, Högl B, Stefani A Tags: J Sleep Res Source Type: research

Restless legs syndrome and health-related quality of life in adults with multiple sclerosis.
Abstract Restless legs syndrome (RLS) is a sleep disorder that may exacerbate many of the symptoms and consequences of multiple sclerosis (MS), and may have further implications for health-related quality of life (HRQOL). The present study examined the relationships among RLS, symptoms and HRQOL in people with MS. Participants with MS (n = 275) completed the Cambridge-Hopkins Restless Legs Syndrome Questionnaire, the International Restless Legs Syndrome Study Group Scale, the Multiple Sclerosis Impact Scale, the Pittsburgh Sleep Quality Index, the Fatigue Severity Scale, the Hospital Anxiety and Depressi...
Source: Journal of Sleep Research - June 3, 2019 Category: Sleep Medicine Authors: Cederberg KLJ, Jeng B, Sasaki JE, Braley TJ, Walters AS, Motl RW Tags: J Sleep Res Source Type: research

Sleep deprivation/sleep restriction and shift work.
PMID: 31131536 [PubMed - in process] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - May 29, 2019 Category: Sleep Medicine Authors: Riemann D Tags: J Sleep Res Source Type: research

Effect of 5-year continuous positive airway pressure treatment on the lipid profile of patients with obstructive sleep apnea: A pilot study.
Abstract Continuous positive airway pressure (CPAP) provides a well-documented symptomatic relief for most patients with obstructive sleep apnea (OSA); however, its effect on dyslipidaemia remains contradictory. The aim of this longitudinal pilot study was to investigate the effect of long-term CPAP treatment on the lipid profile of patients with severe OSA. Fasting serum levels of total cholesterol (TC), low- and high-density lipoprotein cholesterol (LDL-C and HDL-C) and triglyceride (TG) were longitudinally measured in 33 OSA patients with an apnea-hypopnea index (AHI) of ≥30 events/hr, at the time of diagnos...
Source: Journal of Sleep Research - May 26, 2019 Category: Sleep Medicine Authors: Simon B, Gabor B, Barta I, Paska C, Boszormenyi Nagy G, Vizi E, Antus B Tags: J Sleep Res Source Type: research

External validation of a data-driven algorithm for muscular activity identification during sleep.
g F Abstract Several automated methods for scoring periodic limb movements during sleep (PLMS) and rapid eye movement (REM) sleep without atonia (RSWA) have been proposed, but most of them were developed and validated on data recorded in the same clinic, thus they may be biased. This work aims to validate our data-driven algorithm for muscular activity detection during sleep, originally developed based on data recorded and manually scored at the Danish Center for Sleep Medicine. The validation was carried out on a cohort of 240 participants, including de novo Parkinson's disease (PD) patients and neurologically he...
Source: Journal of Sleep Research - May 26, 2019 Category: Sleep Medicine Authors: Cesari M, Christensen JAE, Sorensen HBD, Jennum P, Mollenhauer B, Muntean ML, Trenkwalder C, Sixel-Döring F Tags: J Sleep Res Source Type: research

Interaction effect of obstructive sleep apnea and periodic limb movements during sleep on heart rate variability.
Abstract We aimed at assessing cardiac autonomic function by heart rate variability during sleep in patients with obstructive sleep apnea and periodic limb movements during sleep, and to compare it with that of patients with obstructive sleep apnea only, periodic limb movements during sleep only, and controls. We also aimed at investigating the interaction effect between apnea-hypopnea index and periodic limb movement index on heart rate variability. Four groups of patients (n = 42 each, total = 168) were identified based on the presence/absence of obstructive sleep apnea and periodic l...
Source: Journal of Sleep Research - May 26, 2019 Category: Sleep Medicine Authors: Li X, Covassin N, Zhou J, Zhang Y, Ren R, Yang L, Tan L, Li T, Xue P, Tang X Tags: J Sleep Res Source Type: research

Associations between sleep disturbances, mental health outcomes and burnout in firefighters, and the mediating role of sleep during overnight work: A cross-sectional study.
This study investigated whether sleep disorder risk and mental health outcomes in firefighters were associated with burnout, particularly emotional exhaustion, and examined the mediating role of sleep at work in these relationships. A secondary aim was to investigate associations between habitual sleep characteristics and burnout. North American firefighters (n = 6,307) completed the Maslach Burnout Inventory (emotional exhaustion, depersonalisation, personal accomplishment), and were screened for sleep disorders and self-reported current mental health conditions and sleep characteristics. Multiple logistic r...
Source: Journal of Sleep Research - May 26, 2019 Category: Sleep Medicine Authors: Wolkow AP, Barger LK, O'Brien CS, Sullivan JP, Qadri S, Lockley SW, Czeisler CA, Rajaratnam SMW Tags: J Sleep Res Source Type: research

Temporal shifts in fluid in pulmonary hypertension with and without sleep apnea.
Abstract Overnight extracellular rostral fluid shifts have been shown to be of importance in patients with fluid-retaining states and are associated with a higher prevalence of sleep apnea. Pulmonary hypertension is frequently associated with right ventricular dysfunction and progressive right ventricular failure, and an increased prevalence of sleep apnea has been described. In light of the importance of fluid shifts in the pathophysiology of sleep apnea, we aimed to explore temporal fluid shifts in patients with pulmonary hypertension with and without sleep apnea. Patients with pulmonary hypertension (WHO Group ...
Source: Journal of Sleep Research - May 16, 2019 Category: Sleep Medicine Authors: Carvalho CG, Yadollahi A, Granton J, Ryan CM Tags: J Sleep Res Source Type: research

The pathophysiology of nightmare disorder: Signs of impaired sleep regulation and hyperarousal.
PMID: 31094047 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - May 15, 2019 Category: Sleep Medicine Authors: Simor P, Blaskovich B Tags: J Sleep Res Source Type: research

The prevalence of restless sleep disorder among a clinical sample of children and adolescents referred to a sleep centre.
Abstract Restless sleep disorder (RSD) is a newly described sleep disorder in children characterized by large body movements and repositioning that lasts all night with at least five body movements per hour and a significant impact on daytime behaviours. The authors have previously identified and described the syndrome and compared the sleep parameters and sleep-related movements to those in children with restless legs syndrome, normal controls and snorers. The current study is a retrospective review of the sleep diagnosis in 300 consecutive children seen and evaluated in a single sleep disorders centre; 252 child...
Source: Journal of Sleep Research - May 14, 2019 Category: Sleep Medicine Authors: DelRosso LM, Ferri R Tags: J Sleep Res Source Type: research

Rapid eye movements are reduced in blind individuals.
Abstract There is ongoing controversy regarding the role of rapid eye movements (EMs) during rapid eye movement (REM) sleep. One prevailing hypothesis is that EMs during REM sleep are indicative of the presence of visual imagery in dreams. We tested the validity of this hypothesis by measuring EMs in blind subjects and correlating these with visual dream content. Eleven blind subjects, of whom five were congenitally blind (CB) and six late blind (LB), and 11 matched sighted control (SC) subjects participated in this study. All participants underwent full-night polysomnography (PSG) recordings that were staged manu...
Source: Journal of Sleep Research - April 26, 2019 Category: Sleep Medicine Authors: Christensen JAE, Aubin S, Nielsen T, Ptito M, Kupers R, Jennum P Tags: J Sleep Res Source Type: research

Bed and rise times during the Age of Enlightenment: A case report.
Abstract Studies have shown that our modern electrical lighting environment reduces naturally occurring seasonal variations in sleep-wake rhythms, such as longer sleep during the winter versus summer. However, less is known about how timing and duration of sleep were affected by the seasons in the premodern era, before the invention of electrical lighting. The Swedish researcher Olof Hiorter collected and documented geophysical data every hour during wakefulness in Uppsala, Sweden, between December 1746 and November 1747. In this way, his bed and rise times could be approximated. The data revealed that Hiorter's r...
Source: Journal of Sleep Research - April 22, 2019 Category: Sleep Medicine Authors: van Egmond L, Ekman M, Benedict C Tags: J Sleep Res Source Type: research

The effect of sleep deprivation on objective and subjective measures of facial appearance.
Abstract The faces of people who are sleep deprived are perceived by others as looking paler, less healthy and less attractive compared to when well rested. However, there is little research using objective measures to investigate sleep-loss-related changes in facial appearance. We aimed to assess the effects of sleep deprivation on skin colour, eye openness, mouth curvature and periorbital darkness using objective measures, as well as to replicate previous findings for subjective ratings. We also investigated the extent to which these facial features predicted ratings of fatigue by others and could be used to cla...
Source: Journal of Sleep Research - April 21, 2019 Category: Sleep Medicine Authors: Holding BC, Sundelin T, Cairns P, Perrett DI, Axelsson J Tags: J Sleep Res Source Type: research

Associations between sleep duration and cognitive impairment in mild cognitive impairment.
The objective of this study was to examine the association of objective sleep with cognitive performance in MCI patients. A subsample of 271 participants with a diagnosis of probable Alzheimer's disease (AD; N = 50) or mild cognitive impairment (MCI; N = 121) and 100 persons who were not cognitively impaired (NI) were recruited from a large population-based cohort in the island of Crete, Greece (3140 older adults aged>60 years). All participants underwent extensive neuropsychiatric/neuropsychological evaluation and a 3-day 24-hr actigraphy. Objective sleep variables and their association with ne...
Source: Journal of Sleep Research - April 21, 2019 Category: Sleep Medicine Authors: Basta M, Simos P, Vgontzas A, Koutentaki E, Tziraki S, Zaganas I, Panagiotakis S, Kapetanaki S, Fountoulakis N, Lionis C Tags: J Sleep Res Source Type: research

Infant feeding practices and sleep development in pre-schoolers from the EDEN mother-child cohort.
Abstract Sleep problems affect 20%-30% of toddlers and preschoolers. Few longitudinal studies focused on the impact of infant feeding practices on sleep. We aimed to study the associations between feeding practices up to 8 months and trajectories of sleep quantity or quality from 2 to 5-6 years. Analyses included 1,028 children from the EDEN mother-child cohort. Data were collected by self-administered questionnaires. Associations between feeding practices (breastfeeding, complementary feeding, use of thickened infant formula, night feeding) and sleep trajectories (sleep-onset difficulties, night waking, nighttime...
Source: Journal of Sleep Research - April 16, 2019 Category: Sleep Medicine Authors: Murcia L, Reynaud E, Messayke S, Davisse-Paturet C, Forhan A, Heude B, Charles MA, de Lauzon-Guillain B, Plancoulaine S Tags: J Sleep Res Source Type: research

Link between insomnia and perinatal depressive symptoms: A meta-analysis.
Abstract Evidence shows the possible link between insomnia and perinatal depressive symptoms. In order to find a convergent quantitative answer, we collected data via the search of Medline, EMBASE and reference tracking, which included nine studies (a total sample of 1,922 women). An aggregate effect size estimate (correlation coefficient) was generated using the comprehensive meta-analysis software. For the meta-analytic procedure, a random effects model was set a priori. Moderating factors, including study design, method of assessment of depression, geographical origin of data, publication year, mean age, % marr...
Source: Journal of Sleep Research - April 14, 2019 Category: Sleep Medicine Authors: Emamian F, Khazaie H, Okun ML, Tahmasian M, Sepehry AA Tags: J Sleep Res Source Type: research

Morphometric and functional connectivity changes in the brain of patients with obstructive sleep apnea: A meta-analysis.
Abstract Existing evidence for brain morphometric changes and functional connectivity alterations in patients with obstructive sleep apnea is mixed. The current study aimed to meta-analyse the neuroimaging data, and thus synthesize a brain map showing locations with morphometric and functional connectivity differences between patients with obstructive sleep apnea and controls. Published studies to 2018 were retrieved and included into the analysis if they reported such between-group differences using voxel-based morphometry or resting-state functional magnetic resonance imaging, and reported the results in the for...
Source: Journal of Sleep Research - April 14, 2019 Category: Sleep Medicine Authors: Yeung AWK Tags: J Sleep Res Source Type: research

Definition of excessive daytime sleepiness in the general population: Feeling sleepy relates better to sleep-related symptoms and quality of life than the Epworth Sleepiness Scale score. Results from an epidemiological study.
Abstract Many different subjective tools are being used to measure excessive daytime sleepiness (EDS) but the most widely used is the Epworth Sleepiness Scale (ESS). However, it is unclear if using the ESS is adequate on its own when assessing EDS. The aim of this study was to estimate the characteristics and prevalence of EDS using the ESS and the Basic Nordic Sleep Questionnaire (BNSQ) in general population samples. Participants aged 40 years and older answered questions about sleepiness, health, sleep-related symptoms and quality of life. Two groups were defined as suffering from EDS: those who scored>1...
Source: Journal of Sleep Research - April 10, 2019 Category: Sleep Medicine Authors: Thorarinsdottir EH, Bjornsdottir E, Benediktsdottir B, Janson C, Gislason T, Aspelund T, Kuna ST, Pack AI, Arnardottir ES Tags: J Sleep Res Source Type: research

The effects of zolpidem in obstructive sleep apnea - An open-label pilot study.
Abstract New knowledge on hypnotics and their effects on the phenotypic causes of obstructive sleep apnea indicate that zolpidem has therapeutic potential for certain patients. Specifically, zolpidem increases the threshold for arousal threshold and pharyngeal dilator muscle responsiveness. However, the effects of a standard dose of zolpidem (10 mg) on obstructive sleep apnea severity and symptoms have not been investigated. In an open-label pilot study, 12 unselected people with obstructive sleep apnea were recruited following a diagnostic in-laboratory sleep study. Participants then returned for a single-night...
Source: Journal of Sleep Research - April 10, 2019 Category: Sleep Medicine Authors: Carberry JC, Grunstein RR, Eckert DJ Tags: J Sleep Res Source Type: research

The key role of insomnia and sleep loss in the dysregulation of multiple systems involved in mood disorders: A proposed model.
Abstract Mood disorders are amongst the most prevalent and severe disorders worldwide, with a tendency to be recurrent and disabling. Although multiple mechanisms have been hypothesized to be involved in their pathogenesis, just a few integrative theoretical frameworks have been proposed and have yet to integrate comprehensively all available findings. As such, a comprehensive framework would be quite useful from a clinical and therapeutic point of view in order to identify elements to evaluate and target in the clinical practice. Because conditions of sleep loss, which include reduced sleep duration and insomnia,...
Source: Journal of Sleep Research - April 10, 2019 Category: Sleep Medicine Authors: Palagini L, Bastien CH, Marazziti D, Ellis JG, Riemann D Tags: J Sleep Res Source Type: research

Defining short and long sleep duration for future paediatric research: A systematic literature review.
This study found the best compromise for short sleep was defined as the 2.5th centile (hours = 0.25*age + 11) and long sleep as the 97.5th centile (hours = 0.017*age2  - 0.68*age + 16) of sleep duration in children. Recommendations for the hourly cut-offs of short and long sleep duration based on these percentiles were described. PMID: 30957349 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 7, 2019 Category: Sleep Medicine Authors: Sawyer E, Heussler H, Gunnarsson R Tags: J Sleep Res Source Type: research

Cardiorespiratory fitness and long-term risk of sleep apnea: A national cohort study.
Abstract Sleep apnea is increasing in prevalence, and is an important cause of cardiometabolic diseases and mortality worldwide. Its only established modifiable risk factor is obesity; however, up to half of all sleep apnea cases may occur in non-obese persons, and hence there is a pressing need to identify other modifiable risk factors to facilitate more effective prevention. We sought to examine, for the first time, cardiorespiratory fitness in relation to the risk of sleep apnea, independent of obesity. A national cohort study was conducted to examine cardiorespiratory fitness in all 1,547,478 Swedish military ...
Source: Journal of Sleep Research - April 7, 2019 Category: Sleep Medicine Authors: Crump C, Sundquist J, Winkleby MA, Sundquist K Tags: J Sleep Res Source Type: research

Mortality-risk-based apnea-hypopnea index thresholds for diagnostics of obstructive sleep apnea.
änen T Abstract The severity of obstructive sleep apnea is clinically assessed mainly using the apnea-hypopnea index. Based on the apnea-hypopnea index, patients are classified into four severity groups: non-obstructive sleep apnea (apnea-hypopnea index 
Source: Journal of Sleep Research - April 3, 2019 Category: Sleep Medicine Authors: Korkalainen H, Töyräs J, Nikkonen S, Leppänen T Tags: J Sleep Res Source Type: research

Relation between ambulatory actigraphy and laboratory polysomnography in insomnia practice and research.
Abstract Actigraphy is increasingly used in practice and research studies because of its relative low cost and decreased subject burden. How multiple nights of at-home actigraphy compare to one independent night of in-laboratory polysomnography (PSG) has not been examined in people with insomnia. Using event markers (MARK) to set time in bed (TIB) compared to automatic program analysis (AUTO) has not been systematically evaluated. Subjects (n = 30) meeting DSM-5 criteria for insomnia and in-laboratory PSG sleep efficiency (SE) of
Source: Journal of Sleep Research - April 2, 2019 Category: Sleep Medicine Authors: Withrow D, Roth T, Koshorek G, Roehrs T Tags: J Sleep Res Source Type: research

Respiratory polygraphy in children with sleep-disordered breathing.
In conclusion, the scoring of respiratory events based on RIP flow is scorer dependent even for experienced scorers. The nasal airflow signal is frequently missing in paediatric respiratory polygraphies, which limits the usefulness of the method. PMID: 30932252 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 1, 2019 Category: Sleep Medicine Authors: Gudnadottir G, Hafsten L, Redfors S, Ellegård E, Hellgren J Tags: J Sleep Res Source Type: research

Rapid eye movement fragmentation, not slow-wave sleep, predicts neutral declarative memory consolidation in posttraumatic stress disorder.
This study sought to extend that literature by examining whether, in PTSD-diagnosed individuals, memory-retention deficits are present after a sleep-filled (but not after a wake-filled) delay (i.e., whether memory deficits can be traced to interruptions of sleep-dependent memory consolidation). Moreover, we investigated whether SWS- or REM-based disturbances, or both, contribute to retention deficits. We recruited participants into three groups: PTSD (n = 21), trauma-exposed non-PTSD (TE; n = 19) and healthy control (HC; n = 20). Using a crossover design, we assessed memory recall before and a...
Source: Journal of Sleep Research - April 1, 2019 Category: Sleep Medicine Authors: Lipinska G, Thomas KGF Tags: J Sleep Res Source Type: research

Can spectral power predict subjective sleep quality in healthy individuals?
Abstract The aim of this study was to assess the relationship between electroencephalogram (EEG) power spectral density and subjective sleep quality in healthy individuals. The sample was selected from the archival database of the Sleep Center at the Department for Psychiatry and Psychotherapy, Medical Center - University of Freiburg, and consisted of 206 healthy adults aged 19-73 years (85 male, 121 female) who underwent a polysomnographic examination for two consecutive nights. A multivariate analysis of variance (MANOVA) with spectral power variables of different frequency bands as dependent variables and ...
Source: Journal of Sleep Research - April 1, 2019 Category: Sleep Medicine Authors: Gabryelska A, Feige B, Riemann D, Spiegelhalder K, Johann A, Białasiewicz P, Hertenstein E Tags: J Sleep Res Source Type: research

Old and new methods in sleep research/sleep medicine and insomnia.
PMID: 30834669 [PubMed - in process] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - March 7, 2019 Category: Sleep Medicine Authors: Riemann D Tags: J Sleep Res Source Type: research

Intra-individual stability of NREM sleep quantitative EEG measures in obstructive sleep apnea.
Abstract Electroencephalography is collected routinely during clinical polysomnography, but is often utilised to simply determine sleep time to calculate apnea-hypopnea indices. Quantitative analysis of these data (quantitative electroencephalogram) may provide trait-like information to predict patient vulnerability to sleepiness. Measurements of trait-like characteristics need to have high test-retest reliability. We aimed to investigate the intra-individual stability of slow-wave (delta power) and spindle frequency (sigma power) activity during non-rapid eye movement sleep in patients with obstructive sleep apne...
Source: Journal of Sleep Research - March 1, 2019 Category: Sleep Medicine Authors: Poon JJY, Chapman JL, Wong KKH, Mullins AE, Cho G, Kim JW, Yee BJ, Grunstein RR, Marshall NS, D'Rozario AL Tags: J Sleep Res Source Type: research

From physiological neck myoclonus to sleep related head jerk.
Abstract Neck myoclonus (NM) is a frequent recently described sleep-related motor phenomenon occurring mainly during REM sleep with uncertain effect on sleep continuity. To better describe this phenomenon we studied 11 consecutive drug-free patients undergoing a video-polysomnographic (V-PSG) study who present at least 5 NM events in one single night of recording. All events were measured and checked for their association with rapid eye and leg movements, EEG arousals, awakenings and Bereitschaftspotential. One hundred and eighty-two motor events from 11 subjects were analyzed. Motor events were approximately 0.5&...
Source: Journal of Sleep Research - February 27, 2019 Category: Sleep Medicine Authors: Wolfensberger B, Ferri R, Bianco G, Abbafati M, Miano S, Kaelin-Lang A, Bassetti CL, Manconi M Tags: J Sleep Res Source Type: research

Acute sleep loss induces signs of visual discomfort in young men.
nedict C Abstract Acute sleep loss influences visual processes in humans, such as recognizing facial emotions. However, to the best of our knowledge, no study till date has examined whether acute sleep loss alters visual comfort when looking at images. One image statistic that can be used to investigate the level of visual comfort experienced under visual encoding is the slope of the amplitude spectrum, also referred to as the slope constant. The slope constant describes the spatial distribution of pixel intensities and deviations from the natural slope constant can induce visual discomfort. In the present counter...
Source: Journal of Sleep Research - February 27, 2019 Category: Sleep Medicine Authors: Dyakova O, Rångtell FH, Tan X, Nordström K, Benedict C Tags: J Sleep Res Source Type: research

The role of couple sleep concordance in sleep quality: Attachment as a moderator of associations.
Abstract Despite most American adults sharing a bed with a romantic partner, sleep research has examined sleep primarily as an individual behaviour. A growing body of research indicates that couple bed sharing may have an impact on sleep quality, but the current study is the first to examine whether such associations may differ based on attachment security. A sample of 179 cohabiting heterosexual couples completed daily sleep diaries and surveys of their attachment security, avoidance and anxiety. Data were analysed using multilevel modelling. Greater attachment security and lower attachment avoidance were associa...
Source: Journal of Sleep Research - February 20, 2019 Category: Sleep Medicine Authors: Elsey T, Keller PS, El-Sheikh M Tags: J Sleep Res Source Type: research

Anthropometrical phenotypes are important when explaining obstructive sleep apnea in female bariatric cohorts.
The objective of the study is to investigate whether there is an anthropometric that better explains AHI variability in a sample of morbidly obese women awaiting bariatric surgery (BS). A prospective multicentre cross-sectional study was conducted in consecutive women before BS. Demographic and anthropometric characteristics included age, body mass index (BMI), neck circumference (NC), waist circumference (WC), hip circumference (HC) and waist-to-hip ratio (WHR). OSA was diagnosed by polysomnography. The capacity of anthropometrics to explain AHI variance was investigated using regression linear models. A total of 115 wome...
Source: Journal of Sleep Research - February 11, 2019 Category: Sleep Medicine Authors: Gasa M, López-Padrós C, Monasterio C, Salord N, Mayos M, Vilarrasa N, Fernandez-Aranda F, Montserrat JM, Dorca J Tags: J Sleep Res Source Type: research

Use of targeted memory reactivation enhances skill performance during a nap and enhances declarative memory during wake in healthy young adults.
Abstract Sleep is an important component of motor memory consolidation and learning, providing a critical tool to enhance training and rehabilitation. Following initial skill acquisition, memory consolidation is largely a result of non-rapid eye movement sleep over either a full night or a nap. Targeted memory reactivation is one method used to enhance this critical process, which involves the pairing of an external cue with task performance at the time of initial motor skill acquisition, followed by replay of the same cue during sleep. Application of targeted memory reactivation during sleep leads to increased fu...
Source: Journal of Sleep Research - February 11, 2019 Category: Sleep Medicine Authors: Johnson BP, Scharf SM, Verceles AC, Westlake KP Tags: J Sleep Res Source Type: research

A longitudinal study of polysomnographic variables in patients with mild cognitive impairment converting to Alzheimer's disease.
Abstract The main condition at increased risk of dementia is considered to be mild cognitive impairment. Mild cognitive impairment has been defined as a transitional state between normal aging and dementia, of which it may represent a prodrome. The aim of our study was to evaluate whether sleep variables (both conventional and microstructural ones) in subjects with mild cognitive impairment correlate with conversion to dementia. Nineteen subjects with amnestic mild cognitive impairment (mean age 68.5 ± 7.0 years) and 11 cognitively intact healthy elderly individuals (mean age 69.2 ± 12.6 ...
Source: Journal of Sleep Research - February 6, 2019 Category: Sleep Medicine Authors: Carnicelli L, Maestri M, Di Coscio E, Tognoni G, Fabbrini M, Schirru A, Giorgi FS, Siciliano G, Bonuccelli U, Bonanni E Tags: J Sleep Res Source Type: research

Trait-like characteristics of sleep EEG power spectra in adolescents across sleep opportunity manipulations.
Abstract The electroencephalographic power spectra of non-rapid eye movement sleep in adults demonstrate trait-like consistency within participants across multiple nights, even when prior sleep deprivation is present. Here, we examined the extent to which this finding applies to adolescents who are habitually sleep restricted on school-days and sleep longer on weekends. We evaluated 78 adolescents across three sleep restriction groups who underwent different permutations of adequate sleep (9 hr time-in-bed), sleep restriction (5 hr time-in-bed), afternoon naps (1 hr afternoon) and recovery sleep (9 hr time...
Source: Journal of Sleep Research - February 6, 2019 Category: Sleep Medicine Authors: Ong JL, Lo JC, Patanaik A, Chee MWL Tags: J Sleep Res Source Type: research

Comprehensive coronary plaque assessment in patients with obstructive sleep apnea.
ch-Horvat P Abstract Obstructive sleep apnea (OSA) is associated with an increased risk of cardiovascular disease. Previous studies have assessed the relationship between OSA and coronary artery disease (CAD) using coronary artery calcium score (CAC) measurements. However, limited data are available regarding the association of OSA with non-calcified plaque burden. We therefore aimed to assess the relationship between CAD severity as assessed by coronary computed tomography angiography (CTA) and OSA. Forty-one adult subjects (59 ± 9 years, 15 men) underwent a 256-slice coronary CTA, which was...
Source: Journal of Sleep Research - February 6, 2019 Category: Sleep Medicine Authors: Bikov A, Kolossváry M, Jermendy AL, Drobni ZD, Tarnoki AD, Tarnoki DL, Forgó B, Kovacs DT, Losonczy G, Kunos L, Voros S, Merkely B, Maurovich-Horvat P Tags: J Sleep Res Source Type: research

Am I (hyper)aroused or anxious? Clinical significance of pre-sleep somatic arousal in young adults.
Abstract Self-reported somatic arousal remains a challenging clinical construct, particularly because only a subset of patients report symptoms such as racing heart, palpitations or increased body temperature interfering with their sleep. It is unclear whether self-reported somatic arousal is a marker of hyperarousal or co-morbid clinical anxiety in individuals with insomnia. Participants included 196 young adults aged 20.2 ± 1.0 years old who were predominantly females (75%). About 39% of the sample reported subthreshold insomnia, and about 8% reported clinically significant insomnia, based on their ...
Source: Journal of Sleep Research - February 3, 2019 Category: Sleep Medicine Authors: Puzino K, Frye SS, LaGrotte CA, Vgontzas AN, Fernandez-Mendoza J Tags: J Sleep Res Source Type: research

Epidemiology of sleep disorders, sleep deprivation, dreaming and spindles in sleep.
PMID: 30656780 [PubMed - in process] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - January 19, 2019 Category: Sleep Medicine Authors: Riemann D Tags: J Sleep Res Source Type: research

Corrigendum.
Authors: PMID: 30656781 [PubMed - in process] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - January 19, 2019 Category: Sleep Medicine Tags: J Sleep Res Source Type: research

Effects of evening exposure to electromagnetic fields emitted by 3G mobile phones on health and night sleep EEG architecture.
rt L Abstract Studies on sleep after exposure to radiofrequency electromagnetic fields have shown mixed results. We investigated the effects of double-blind radiofrequency exposure to 1,930-1,990 MHz, UMTS 3G signalling standard, time-averaged 10 g specific absorption rate of 1.6 W kg-1 on self-evaluated sleepiness and objective electroencephalogram architecture during sleep. Eighteen subjects aged 18-19 years underwent 3.0 hr of controlled exposure on two consecutive days 19:45-23:00 hours (including 15-min break); active or sham prior to sleep, followed by full-night 7.5 hr polysomnographic recor...
Source: Journal of Sleep Research - January 15, 2019 Category: Sleep Medicine Authors: Lowden A, Nagai R, Åkerstedt T, Hansson Mild K, Hillert L Tags: J Sleep Res Source Type: research