Interhemispheric sleep depth coherence predicts driving safety in sleep apnea.
Abstract Obstructive sleep apnea is associated with increased risk of car crashes; however, conventional measures of sleep apnea severity do not clearly identify those individuals who are at greatest risk. Here we tested whether, among individuals with sleep apnea, those with reduced interhemispheric sleep depth coherence, measured by correlation between right and left hemisphere odds ratio product, are at greater risk. The sample was derived from the Sleep Heart Health Study, a prospective observational cohort study, and included 1,378 adults with sleep apnea. The occurrence of a car crash was ascertained by a qu...
Source: Journal of Sleep Research - May 22, 2020 Category: Sleep Medicine Authors: Azarbarzin A, Younes M, Sands SA, Wellman A, Redline S, Czeisler CA, Gottlieb DJ Tags: J Sleep Res Source Type: research

Relationship between sleep characteristics and markers of inflammation in Swedish women from the general population.
In conclusion, sleep disturbances (self-reported), specifically difficulties maintaining sleep and early morning awakenings, but not sleep duration (neither subjective nor objective), were associated with higher CRP levels. No association was found with IL-6 or TNFα. Elevated REM sleep was associated with lower CRP levels. The results suggest that inflammation might be an intermediate mechanism linking sleep and health in women. PMID: 32441868 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - May 22, 2020 Category: Sleep Medicine Authors: Ghilotti F, Bellocco R, Trolle Lagerros Y, Thorson A, Theorell-Haglöw J, Åkerstedt T, Lindberg E Tags: J Sleep Res Source Type: research

Predictors of changes in subjective daytime sleepiness in response to CPAP therapy withdrawal in OSA: A post-hoc analysis.
Abstract Subjective sleepiness is the hallmark symptom of untreated obstructive sleep apnea (OSA) and leads to an increased risk of motor vehicle accidents and impaired quality of life. Continuous positive airway pressure (CPAP) is the standard therapy for OSA and improves sleepiness. The aim was to identify factors that might predict recurrence of sleepiness in times off CPAP and to define OSA patient types with a likely effect of CPAP on sleepiness. A post-hoc analysis of six clinical trials, including 132 patients with OSA effectively treated with CPAP prior to study inclusion, who were allocated to 2 week...
Source: Journal of Sleep Research - May 22, 2020 Category: Sleep Medicine Authors: Roeder M, Sievi NA, Kohler M, Schwarz EI Tags: J Sleep Res Source Type: research

Comparing manual and automatic scoring of sleep monitoring data from portable polygraphy.
G, Goebel V Abstract We used sleep monitoring data from a study that investigated the prevalence, characteristics, risk factors and type of sleep apnea (SA) in 579 patients with paroxysmal atrial fibrillation. Most patients were screened for two nights, resulting in 1,043 sleep recordings that each contained data from one night. SA was diagnosed using the Nox T3 portable sleep monitor. An experienced sleep specialist scored the recordings manually using Noxturnal software. A total of 157 women (27%) and 422 men (73%) were examined; 477 (82.7%) had an apnea-hypopnea index (AHI) ≥ 5/hr, whereas moderate to severe...
Source: Journal of Sleep Research - May 20, 2020 Category: Sleep Medicine Authors: Kristiansen S, Traaen GM, Øverland B, Plagemann T, Gullestad L, Akre H, Nikolaidis K, Aakerøy L, Hunt TE, Loennechen JP, Steinshamn S, Bendz C, Anfinsen OG, Goebel V Tags: J Sleep Res Source Type: research

Subjective-objective sleep discrepancy in patients with insomnia during and after cognitive behavioural therapy: An actigraphy study.
In conclusion, both groups differing in sleep perception responded similarly to cognitive behavioural therapy for insomnia, although different In conclusion, both groups differing in sleep perception responded similarly to cognitive behavioural therapy for insomnia, although different therapeutic components could play important roles in each group. components could play important roles in each group. PMID: 32431047 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - May 20, 2020 Category: Sleep Medicine Authors: Janků K, Šmotek M, Fárková E, Kopřivová J Tags: J Sleep Res Source Type: research

Short- and long-term mortality following hypnotic use.
g;kerstedt T Abstract Potential long-term consequences of hypnotics remain controversial. We used the prospective Swedish National March Cohort, a study based on 41,695 participants with a mean follow-up duration of 18.9 years. Logistic regression models and Cox proportional hazards models with attained age as timescale were used to assess associations of hypnotic use with short- and long-term mortality. The proportion of subjects who initiated or discontinued hypnotic use during follow-up was substantial. All groups of hypnotics were associated with increased mortality within 2 years after a first prescripti...
Source: Journal of Sleep Research - May 18, 2020 Category: Sleep Medicine Authors: Hedström AK, Hössjer O, Trolle Lagerros Y, Åkerstedt T Tags: J Sleep Res Source Type: research

Changes in sleep pattern, sense of time and digital media use during COVID-19 lockdown in Italy.
Abstract Italy is one of the major COVID-19 hotspots. To reduce the spread of the infections and the pressure on Italian healthcare systems, since March 10, 2020, Italy has been under a total lockdown, forcing people into home confinement. Here we present data from 1,310 people living in the Italian territory (Mage  = 23.91 ± 3.60 years, 880 females, 501 workers, 809 university students), who completed an online survey from March 24 to March 28, 2020. In the survey, we asked participants to think about their use of digital media before going to bed, their sleep pattern and their sub...
Source: Journal of Sleep Research - May 15, 2020 Category: Sleep Medicine Authors: Cellini N, Canale N, Mioni G, Costa S Tags: J Sleep Res Source Type: research

Trends in the use of medications with insomnia side effects and the implications for insomnia among US adults.
Abstract Americans are increasingly consuming pharmaceuticals that although effective in treating their focal indication, include insomnia as a side effect. Regardless, no studies have documented trends in the concurrent use of these medications and their implications for insomnia among community-dwelling adults. Using a nationally representative sample of US adults from the 1999-2016 National Health and Nutrition Examination Survey (NHANES), this study shows that the concurrent use of medications with insomnia as a potential side effect ("insomnia side effects" hereafter) has increased considerably in t...
Source: Journal of Sleep Research - May 15, 2020 Category: Sleep Medicine Authors: Do D Tags: J Sleep Res Source Type: research

Risk factors of excessive daytime sleepiness in a prospective population-based cohort.
Abstract Although excessive daytime sleepiness is commonly evaluated in clinical and research settings using the Epworth Sleepiness Scale, few studies have assessed the factors associated with its incidence in the general population. We prospectively investigated the predictors of incident and persistent excessive daytime sleepiness in 2,751 subjects (46.1% men, mean age 56.0 ± 9.8 years) from the CoLaus-PsyCoLaus population-based cohort (Lausanne, Switzerland) over 5 years. Participants completed the Epworth Sleepiness Scale and the Pittsburgh Sleep Quality Index, and underwent a full c...
Source: Journal of Sleep Research - May 15, 2020 Category: Sleep Medicine Authors: Berger M, Hirotsu C, Haba-Rubio J, Betta M, Bernardi G, Siclari F, Waeber G, Vollenweider P, Marques-Vidal P, Heinzer R Tags: J Sleep Res Source Type: research

Temporal associations between morningness/eveningness, problematic social media use, psychological distress and daytime sleepiness: Mediated roles of sleep quality and insomnia among young adults.
kpour AH Abstract The extant literature has suggested relationships between an individual's chronotype (in relation to morningness/eveningness) and several outcomes, including addictive disorders, psychological distress and daytime sleepiness. Moreover, sleep quality has been proposed to be a mediator in the aforementioned relationships. Consequently, the aim of the present study was to investigate the complex relationship between morningness/eveningness, problematic social media use, psychological distress and daytime sleepiness, with the potential mediators of sleep quality and insomnia. All participants (N ...
Source: Journal of Sleep Research - May 14, 2020 Category: Sleep Medicine Authors: Lin CY, Imani V, Griffiths MD, Broström A, Nygårdh A, Demetrovics Z, Pakpour AH Tags: J Sleep Res Source Type: research

Zolpidem overutilisation among Korean patients with insomnia.
This study aimed to investigate zolpidem overutilisation among Korean patients with insomnia. We analysed the National Patient Sample (NPS) data compiled by the Health Insurance Review & Assessment Service (HIRA-NPS) in 2016. Zolpidem overutilisation was defined as when a patient used zolpidem for longer than 30 consecutive days and prescriptions overlapped with more than 10% of total prescription periods. Demographic and clinical factors associated with the overutilisation of zolpidem were investigated using a logistic regression model. The proportion of zolpidem overutilisers was estimated at 5.0%. Factors such as ag...
Source: Journal of Sleep Research - May 14, 2020 Category: Sleep Medicine Authors: Kim H, Park S, Kim J, Je NK Tags: J Sleep Res Source Type: research

On the rise and fall of the apnea-hypopnea index: A historical review and critical appraisal.
Abstract The publication of "The Sleep Apnea Syndromes" by Guilleminault et al. in the 1970s hallmarked the discovery of a new disease entity involving serious health consequences. Obstructive sleep apnea was shown to be the most important disorder among the sleep apnea syndromes (SAS). In the course of time, it was found that the prevalence of obstructive sleep apnea reached the proportions of a global epidemic, with a major impact on public health, safety and the economy. Early on, a metric was introduced to gauge the seriousness of obstructive sleep apnea, based on the objective measurement of respira...
Source: Journal of Sleep Research - May 14, 2020 Category: Sleep Medicine Authors: Pevernagie DA, Gnidovec-Strazisar B, Grote L, Heinzer R, McNicholas WT, Penzel T, Randerath W, Schiza S, Verbraecken J, Arnardottir ES Tags: J Sleep Res Source Type: research

Effects of insomnia symptoms and objective short sleep duration on memory performance in youths.
Abstract Sleep quantity and quality are both important for optimal development and functioning during youth. Yet few studies have examined the effects of insomnia symptoms and objective short sleep duration on memory performance among adolescents and young adults. One-hundred and ninety participants (female: 61.6%) aged from 12 to 24 years completed this study. All participants underwent a clinical interview, a 7-day actigraphic assessment, a battery of self-report questionnaires and cognitive tests to assess working memory and episodic memory. Insomnia symptoms were defined as a score ≥ 9 on the...
Source: Journal of Sleep Research - May 12, 2020 Category: Sleep Medicine Authors: Ling J, Sun W, Chan NY, Zhang J, Lam SP, Li AM, Chan JWY, Kyle SD, Li SX Tags: J Sleep Res Source Type: research

The prevalence of excessive sleepiness is higher in shift workers than in patients with obstructive sleep apnea.
This study emphasizes the presence of EDS in a shift work group of civil aviation professionals, which exceeded the EDS level of a positive control group of OSA patients. Sleep hygiene education for companies' workers and management is important and mitigation strategies should be implemented to reduce excessive sleepiness among workers. PMID: 32395904 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - May 12, 2020 Category: Sleep Medicine Authors: Reis C, Staats R, Pellegrino P, Alvarenga TA, Bárbara C, Paiva T Tags: J Sleep Res Source Type: research

Association between morningness-eveningness, sleep duration, weekend catch-up sleep and depression among Korean high-school students.
Abstract The present study aimed to examine the association between morningness-eveningness preferences, sleep duration, weekend catch-up sleep duration and depression among Korean high-school students. A total of 8,655 high-school students participated from 15 districts in South Korea and completed an online self-report questionnaire. The following sleep characteristics were assessed: weekday and weekend sleep duration, weekend catch-up sleep duration, morningness-eveningness preference, perceived sufficiency of sleep, self-reported snoring and sleep apnea, daytime sleepiness, and sleep environment. Age, gender, ...
Source: Journal of Sleep Research - May 11, 2020 Category: Sleep Medicine Authors: Koo DL, Yang KI, Kim JH, Kim D, Sunwoo JS, Hwangbo Y, Lee HR, Hong SB Tags: J Sleep Res Source Type: research

Effects of chronic sleep deprivation on upper respiratory tract mucosal histology and mucociliary clearance on rats.
In this study, we aimed to investigate the effects of chronic sleep deprivation on mucociliary clearance, which is the primary defence mechanism of the upper airway tract and nasal mucosal histology. Forty-two Wistar Albino rats (250-300 g), 8 or 12 weeks old, were randomly assigned into three groups as follows. The first sleep-deprivation group consisted of 14 rats (A), another 14 of them were assigned to platform group (B), and the remaining 14 were included to the home cage control group (C). For the two deprivation groups (A and B), the modified multiple platform method (MMPM) was used to induce sleep deprivation ...
Source: Journal of Sleep Research - May 8, 2020 Category: Sleep Medicine Authors: Sazak Kundi FC, Murat Ozcan K, Okudan B, Coskun N, Inan MA, Ozcan M Tags: J Sleep Res Source Type: research

The impact of short sleep on food reward processes in adolescents.
Abstract Short sleep has been linked to adolescent risk of obesity, but questions remain regarding the dietary mechanisms by which this occurs. We tested whether mildly shortening sleep influences how rewarding and appealing healthy adolescents find several kinds of foods. Eighty-eight healthy adolescents completed a within-subjects crossover sleep experiment comparing 5 days of Short Sleep (6.5 hr sleep opportunity) with 5 days of Healthy Sleep (9.5 hr sleep opportunity). Following each condition, adolescents completed measures of food appeal and reinforcing value of food across five food type...
Source: Journal of Sleep Research - May 7, 2020 Category: Sleep Medicine Authors: Duraccio KM, Krietsch KN, Zhang N, Whitacre C, Howarth T, Pfeiffer M, Beebe DW Tags: J Sleep Res Source Type: research

The effect of caffeine abstinence on sleep among habitual caffeine users with poor sleep.
Abstract Caffeine is the most widely used psychoactive substance in the world and is known to disrupt healthy sleep. However, very few studies have directly tested the effect of caffeine abstinence on sleep, and these have yielded inconsistent findings. The purpose of the present study was to examine changes in sleep following caffeine abstinence and examine the extent to which characteristics of habitual caffeine use moderated this change. Participants included 66 healthy, young adults with habitual caffeine use and poor sleep. During the 2-week baseline, sleep was assessed using wrist actigraphy and daily caffei...
Source: Journal of Sleep Research - May 6, 2020 Category: Sleep Medicine Authors: Irish LA, Mead MP, Cao L, Veronda AC, Crosby RD Tags: J Sleep Res Source Type: research

Hippocampal and medial prefrontal cortical volume is associated with overnight declarative memory consolidation independent of specific sleep oscillations.
Abstract The current study was designed to further clarify the influence of brain morphology, sleep oscillatory activity and age on memory consolidation. Specifically, we hypothesized, that a smaller volume of hippocampus, parahippocampal and medial prefrontal cortex negatively impacts declarative, but not procedural, memory consolidation. Explorative analyses were conducted to demonstrate whether a decrease in slow-wave activity negatively impacts declarative memory consolidation, and whether these factors mediate age effects on memory consolidation. Thirty-eight healthy participants underwent an acquisition sess...
Source: Journal of Sleep Research - May 6, 2020 Category: Sleep Medicine Authors: Frase L, Regen W, Kass S, Rambach A, Baglioni C, Feige B, Hennig J, Riemann D, Nissen C, Spiegelhalder K Tags: J Sleep Res Source Type: research

Exposure to total 36-hr sleep deprivation reduces physiological and psychological thermal strain to whole-body uncompensable passive heat stress in young adult men.
Abstract Total sleep deprivation (TSD) is associated with endothelial dysfunction and a consequent decrease in vascular reactivity and increase in peripheral vascular resistance. These effectors compromise the body's ability to thermoregulate in hot and cold stress conditions. We investigated heat-unacclimated young adult men (26 ± 2 years) to determine whether 36 hr of TSD compared to an 8 or 4-hr sleep condition, would suppress the responses of the autonomic system (body rectal temperature [Tre ], heart rate [HR], root mean square of successive interbeat intervals, physiological strain...
Source: Journal of Sleep Research - May 4, 2020 Category: Sleep Medicine Authors: Cernych M, Satas A, Rapalis A, Marozas V, Malciene L, Lukosevicius A, Daniuseviciute L, Brazaitis M Tags: J Sleep Res Source Type: research

Sleep neurophysiology in childhood onset schizophrenia.
This study demonstrates the utility of the sleep EEG for studying vulnerable populations and its potential to aid diagnosis. PMID: 32350968 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 30, 2020 Category: Sleep Medicine Authors: Markovic A, Buckley A, Driver DI, Dillard-Broadnax D, Gochman PA, Hoedlmoser K, Rapoport JL, Tarokh L Tags: J Sleep Res Source Type: research

REM sleep behaviour disorder in essential tremor: A polysomnographic study.
l;a M Abstract Our objectives were to assess the prevalence of REM sleep behaviour disorder in patients with Essential Tremor, using video-polysomnography and to compare REM sleep behaviour disorder features in essential tremor with those of patients with alpha-synucleinopathies. Forty-nine patients with essential tremor were screened with the REM Sleep Behaviour Disorder Screening Questionnaire. Patients scoring positive and those with spontaneous complaints of REM sleep behaviour disorder (n = 6) underwent video-polysomnography. The clinical features of essential tremor were compared between patients w...
Source: Journal of Sleep Research - April 23, 2020 Category: Sleep Medicine Authors: Bugalho P, Salavisa M, Borbinha C, Fernandes M, Meira B, Barbosa R, Mendonça M Tags: J Sleep Res Source Type: research

YouTube as a source of information for narcolepsy: A content-quality and optimization analysis.
i P Abstract YouTube is the world's most popular video-sharing site that in recent years has become an important platform for patients in finding educational information about their disease. The purpose of this study was to assess the quality and reliability of narcolepsy-related YouTube videos. We searched the key terms "Narcolepsy", "Narcolepsy-cataplexy," "Narcolepsy excessive daytime sleepiness" and "Narcolepsy excessive drowsiness" on YouTube. 80 videos were analyzed as they meet the inclusion criteria. Quantitative and qualitative metrics were recorded and the videos w...
Source: Journal of Sleep Research - April 21, 2020 Category: Sleep Medicine Authors: Szmuda T, Özdemir C, Fedorow K, Ali S, Słoniewski P Tags: J Sleep Res Source Type: research

Evidence against a large effect of sleep in protecting verbal memories from interference.
nauer M Abstract The human brain has evolved to acquire novel information rapidly while serving the need to store long-term memories in a stable and lasting form. Presenting interfering information directly after learning can lead to forgetting of the original material. It has been suggested that sleep aids the stabilization of new memories and protects them from interference. Here, we aim to replicate in two separate experiments the claim that sleep protects memories from retroactive interference (Current Biology, 16, 2006 and 1290; PLoS ONE, 4, 2009 and e4117). We let participants study wordlists before letting ...
Source: Journal of Sleep Research - April 20, 2020 Category: Sleep Medicine Authors: Pöhlchen D, Pawlizki A, Gais S, Schönauer M Tags: J Sleep Res Source Type: research

Dynamic tongue area measurements in ultrasound images for adults with obstructive sleep apnea.
Abstract Obstructive sleep apnea is a chronic breathing disorder where the recursive collapse of the upper airway causes cessation of airflow during sleep. Quantitative assessments of dynamic tongue motion may provide a better understanding of the mechanism of obstructive sleep apnea. Tongue area changes, in submental ultrasound images recorded during wakefulness from normal breathing by the Müller manoeuvre, were tracked using the modified optical flow-based method. The results demonstrated that patients with obstructive sleep apnea had a larger mid-sagittal tongue area compared to the control group (during ...
Source: Journal of Sleep Research - April 17, 2020 Category: Sleep Medicine Authors: Manlises CO, Chen JW, Huang CC Tags: J Sleep Res Source Type: research

Acute sleep deprivation elevates brain and body temperature in rats.
Abstract Available sleep deprivation studies lack data on simultaneous changes in hypothalamic, cortical and body temperature during sleep deprivation and recovery. Ten adult male Wistar rats chronically implanted with electroencephalogram, electro-oculogram and electromyogram electrodes for recording sleep were used in this study. Hypothalamic and cortical temperatures were measured by pre-implanted thermocouples. A radio transmitter (TA10TAF-40, DSI USA) was implanted intraperitoneally to measure body temperature. All the temperatures were measured simultaneously at 15-s intervals during baseline conditions, sle...
Source: Journal of Sleep Research - April 16, 2020 Category: Sleep Medicine Authors: Vishwakarma LC, Sharma B, Singh V, Jaryal AK, Mallick HN Tags: J Sleep Res Source Type: research

Obstructive sleep apnea is associated with coronary microvascular dysfunction: A systematic review from a clinical perspective.
In conclusion, there are plausible biological mechanisms linking OSA and CMD, and the preponderance of evidence from this systematic review suggests that OSA, especially severe OSA, is associated with reduced CFR. Future studies are warranted to further delineate the exact role of OSA in CMD occurrence and development in a prospective setting. PMID: 32293774 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 15, 2020 Category: Sleep Medicine Authors: Zhang RH, Zhao W, Shu LP, Wang N, Cai YH, Yang JK, Zhou JB, Qi L Tags: J Sleep Res Source Type: research

Maternal perinatal depression and infant sleep problems at 1  year of age: Subjective and actigraphy data from a population-based birth cohort study.
In conclusion, although mothers in the depressed group were more likely to report more night wakings, objective data from actigraphy did not replicate this finding. Dysfunctional cognition, maternal behavioural factors and sleep impairment associated with perinatal depression may affect the mother's impression of her infant's sleep. PMID: 32285520 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 14, 2020 Category: Sleep Medicine Authors: Halal CS, Bassani DG, Santos IS, Tovo-Rodrigues L, Del-Ponte B, Silveira MF, Bertoldi AD, Barros FC, Nunes ML Tags: J Sleep Res Source Type: research

Intraocular cataract lens replacement and light exposure potentially impact procedural learning in older adults.
Abstract Procedural learning declines with age and appropriately timed light exposure can improve cognitive performance in older individuals. Because cataract reduces light transmission and is associated with cognitive decline in older adults, we explored whether lens replacement (intraocular blue-blocking [BB] or UV-only blocking) in older patients with cataracts enhances the beneficial effects of light on procedural learning. Healthy older participants (n = 16) and older patients with post-cataract surgery (n = 13 with BB or UV lens replacement) underwent a randomized within-subject...
Source: Journal of Sleep Research - April 14, 2020 Category: Sleep Medicine Authors: Chellappa SL, Bromundt V, Frey S, Schlote T, Goldblum D, Cajochen C, Reichert CF Tags: J Sleep Res Source Type: research

Actigraphy measurement of physical activity and energy expenditure in narcolepsy type 1, narcolepsy type 2 and idiopathic hypersomnia: A Sensewear Armband study.
g P Abstract The cause of obesity in narcolepsy type 1 (NT1) patients is not fully understood. The present study investigated if a reduced physical activity could explain weight gain in NT1. Seventy-nine patients were included in this retrospective study and divided into an NT1 group (n = 56) and a non-NT1 group (n = 23), including NT2 and idiopathic hypersomnia (IH). Accelerometry-derived measures of physical activity, total energy expenditure and skin temperature were collected from patients during seven consecutive days without medication. In addition, results from multiple sleep latency tes...
Source: Journal of Sleep Research - April 13, 2020 Category: Sleep Medicine Authors: Bornstein A, Hedström A, Wasling P Tags: J Sleep Res Source Type: research

Exploding head syndrome, chronotype, parasomnias and mental health in young adults.
This study provides valuable insight into young peoples' sleep experiences and key factors associated with EHS. PMID: 32282101 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - April 13, 2020 Category: Sleep Medicine Authors: Kirwan E, Fortune DG Tags: J Sleep Res Source Type: research

Association of sleep spindle characteristics with executive functioning in healthy sedentary middle-aged and older adults.
Abstract To determine the relationship between sleep spindle characteristics (density, power and frequency), executive functioning and cognitive decline in older adults, we studied a convenience subsample of healthy middle-aged and older participants of the Brain in Motion study. Participants underwent a single night of unattended in-home polysomnography with neurocognitive testing carried out shortly afterwards. Spectral analysis of the EEG was performed to derive spindle characteristics in both central and frontal derivations during non-rapid eye movement (NREM) Stage 2 and 3. Multiple linear regressions were us...
Source: Journal of Sleep Research - April 12, 2020 Category: Sleep Medicine Authors: Guadagni V, Byles H, Tyndall AV, Parboosingh J, Longman RS, Hogan DB, Hanly PJ, Younes M, Poulin MJ Tags: J Sleep Res Source Type: research

Association between proteomics and obstructive sleep apnea phenotypes in a community-based cohort of women.
g E Abstract Proteomic-based technologies offer new opportunities to identify proteins that might reflect the cardiometabolic stress caused by different aspects of sleep-disordered breathing. We aimed to investigate whether severe obstructive sleep apnea and severe obstructive sleep apnea during rapid eye movement sleep are associated with changed levels of inflammatory and cardiac disease-related proteins in a population-based cohort of women. In the community-based "Sleep and Health in Women" (SHE) cohort study, 400 women underwent polysomnography, anthropometric measurements and blood sampling. Two pr...
Source: Journal of Sleep Research - April 8, 2020 Category: Sleep Medicine Authors: Ljunggren M, Theorell-Haglöw J, Freyhult E, Sahlin C, Franklin KA, Malinovschi A, Janson C, Lindberg E Tags: J Sleep Res Source Type: research

Prevalence and predictors of mood disturbances in idiopathic REM sleep behaviour disorder.
Abstract Depression and anxiety are commonly associated with synucleinopathies. Mood disturbances have also been reported in patients with idiopathic REM sleep behaviour disorder (iRBD) and are difficult to treat due to exacerbation of sleep symptoms with standard antidepressants. Despite this, detailed prevalence studies of mood symptomatology and contributors to mood disturbances in iRBD are limited. Mood, sleep, autonomic, cognitive and motor symptoms were assessed in 49 well-characterized patients with iRBD using a variety of clinical scales. Spearman correlations, factor analysis and multiple linear regressio...
Source: Journal of Sleep Research - April 7, 2020 Category: Sleep Medicine Authors: Chiu NKH, Ehgoetz Martens KA, Mok VCT, Lewis SJG, Matar E Tags: J Sleep Res Source Type: research

Sleep enhances strategic thinking at the expense of basic procedural skills consolidation.
Abstract Recent studies show that sleep facilitates the learning of complex cognitive skills. Here, we assess the effect of sleep on performance in an ecological, multi-componential task, which requires subjects to trace on a screen as many words as possible with 16 letters, some of which ("bonuses") multiply the value of letters or words containing them. In a within-subjects design, 23 healthy adults underwent training and retest, with a retention period (approximately 8 hr) spent awake (WK, with training in the morning and retest in the afternoon) or asleep (SL, with training in the evening and re...
Source: Journal of Sleep Research - April 7, 2020 Category: Sleep Medicine Authors: Conte F, Cerasuolo M, Giganti F, Ficca G Tags: J Sleep Res Source Type: research

The impact of five nights of sleep restriction on emotional reactivity.
In this study, we evaluated, for the first time, the effects of five nights of sleep restriction (5 hr a night) on emotional reactivity in healthy subjects. Forty-two subjects were selected to participate, over two consecutive weeks, in two experimental conditions in counterbalanced order. The subjects were tested the morning after five nights of regular sleep and after five consecutive nights of sleep restriction. During the test, participants evaluated valence and arousal of 90 images selected from the International Affective Picture System. The subjects perceived pleasant and neutral pictures in a more negative way...
Source: Journal of Sleep Research - April 7, 2020 Category: Sleep Medicine Authors: Tempesta D, Salfi F, De Gennaro L, Ferrara M Tags: J Sleep Res Source Type: research

Dealing with sleep problems during home confinement due to the COVID-19 outbreak: practical recommendations from a task force of the European CBT-I Academy.
n D Abstract In the current global home confinement situation due to the COVID-19 outbreak, most individuals are exposed to an unprecedented stressful situation of unknown duration. This may not only increase daytime stress, anxiety and depression levels but also disrupt sleep. Importantly, because of the fundamental role that sleep plays in emotion regulation, sleep disturbance can have direct consequences upon next day emotional functioning. In this paper we summarize what is known about the stress-sleep link and confinement as well as effective insomnia treatment. We discuss those effects of the current home co...
Source: Journal of Sleep Research - April 4, 2020 Category: Sleep Medicine Authors: Altena E, Baglioni C, Espie CA, Ellis J, Gavriloff D, Holzinger B, Schlarb A, Frase L, Jernelöv S, Riemann D Tags: J Sleep Res Source Type: research

Sleep among primary care physicians-Association with overtime, night duties and strategies to counteract poor sleep quality.
This study examines if there are any differences in how working either long hours or at night duties relates to self-reported sleep time, sleep quality and daytime sleepiness in primary care physicians. We analyzed data from a survey research of 807 participants. Respondents were divided into four groups based on their reported work hours per week and number of nights on duty per month. Overtime was associated with shorter sleep time and worse subjective sleep quality even when compared with that of participants who work on night duties. All investigated groups of participants reported short sleep latencies which suggests ...
Source: Journal of Sleep Research - April 3, 2020 Category: Sleep Medicine Authors: Gustavsson K, Wierzbicka A, Matuszczyk M, Matuszczyk M, Wichniak A Tags: J Sleep Res Source Type: research

Reduced dynamic functional connectivity between salience and executive brain networks in insomnia disorder.
This study assessed between-network functional connectivity strength and variability in patients with insomnia disorder as compared with matched controls without sleep complaints. Twelve-minute resting-state functional magnetic resonance images and T1-weighed images were acquired in 65 people diagnosed with insomnia disorder (21-69 years, 48 female) and 65 matched controls without sleep complaints (22-70 years, 42 female). Pairwise correlations between the activity time series of 14 resting-state networks and temporal variability of the correlations were compared between cases and controls. After false discovery ...
Source: Journal of Sleep Research - March 13, 2020 Category: Sleep Medicine Authors: Wei Y, Leerssen J, Wassing R, Stoffers D, Perrier J, Van Someren EJW Tags: J Sleep Res Source Type: research

Cognitive behavioural therapy for insomnia (CBTi): From randomized controlled trials to practice guidelines to implementation in clinical practice.
PMID: 32164036 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - March 13, 2020 Category: Sleep Medicine Authors: Morin CM Tags: J Sleep Res Source Type: research

Sleep structure in sleep bruxism: A polysomnographic study including bruxism activity phenotypes across sleep stages.
Abstract The aim of the study was to assess sleep structure, phenotypes related to bruxism activity and basic respiratory parameters among a large group of participants with sleep bruxism and without obstructive sleep apnea. Adult participants with clinical suspicion of sleep bruxism and with no other significant medical history were recruited. Video-polysomnography was performed to detect masseter muscles activity. Polysomnographic scoring was performed according to the American Academy of Sleep Medicine Criteria. Finally, 146 participants were included. The participants were divided into three subgroups: severe,...
Source: Journal of Sleep Research - March 11, 2020 Category: Sleep Medicine Authors: Wieczorek T, Wieckiewicz M, Smardz J, Wojakowska A, Michalek-Zrabkowska M, Mazur G, Martynowicz H Tags: J Sleep Res Source Type: research

Effect of cognitive behavioural therapy on sleep and opioid medication use in adults with fibromyalgia and insomnia.
Abstract Sleep and opioid medications used to treat insomnia and chronic pain are associated with adverse side effects (falls and cognitive disturbance). Although behavioural treatments such as cognitive behavioral therapy for insomnia (CBT-I) and pain (CBT-P) improve sleep and clinical pain, their effects on sleep and opioid medication use are unclear. In this secondary analysis of published trial data, we investigated whether CBT-I and CBT-P reduced reliance on sleep/opioid medication in patients with fibromyalgia and insomnia (FMI). Patients with FMI (n = 113, Mage  = 53.0, SD = 10...
Source: Journal of Sleep Research - March 3, 2020 Category: Sleep Medicine Authors: McCrae CS, Curtis AF, Miller MB, Nair N, Rathinakumar H, Davenport M, Berry JR, McGovney K, Staud R, Berry R, Robinson M Tags: J Sleep Res Source Type: research

Escitalopram for recurrent isolated sleep paralysis.
We report the first two cases of escitalopram used to successfully treat recurrent isolated sleep paralysis. Escitalopram, the most selective of the selective serotonin reuptake inhibitors, generally improves subjective sleep quality, making it an appealing treatment option. PMID: 32112511 [PubMed - as supplied by publisher] (Source: Journal of Sleep Research)
Source: Journal of Sleep Research - February 29, 2020 Category: Sleep Medicine Authors: Hintze JP, Gault D Tags: J Sleep Res Source Type: research

Racial/ethnic disparities in sleep duration and sleep disturbances among pregnant and non-pregnant women in the United States.
Abstract Sleep disturbances among pregnant women are increasingly linked to suboptimal maternal/birth outcomes. Few studies in the USA investigating sleep by pregnancy status have included racially/ethnically diverse populations, despite worsening disparities in adverse birth outcomes. Using a nationally representative sample of 71,644 (2,349 pregnant) women from the National Health Interview Survey (2004-2017), we investigated relationships between self-reported pregnancy and six sleep characteristics stratified by race/ethnicity. We also examined associations between race/ethnicity and sleep stratified by pregna...
Source: Journal of Sleep Research - February 29, 2020 Category: Sleep Medicine Authors: Feinstein L, McWhorter KL, Gaston SA, Troxel WM, Sharkey KM, Jackson CL Tags: J Sleep Res Source Type: research

Long-term benefits of digital cognitive behavioural therapy for insomnia: Follow-up report from a randomized clinical trial.
Abstract Digital cognitive behavioural therapy (dCBT) is an effective treatment for chronic insomnia and also improves well-being and quality of life (QoL). We assessed whether these benefits are sustained and if the effects of dCBT extend to the use of sleep medication and healthcare. In total 1,711 adults (48.0 ± 13.8 years, 77.6% female) with complaints of chronic insomnia participated in a previously published randomized controlled trial (ISRCTN 60530898) comparing dCBT (n = 853) with sleep hygiene education (SHE, n = 858). At weeks 0, 4, 8, 24, 36 and 48, we assessed ...
Source: Journal of Sleep Research - February 28, 2020 Category: Sleep Medicine Authors: Luik AI, Marsden A, Emsley R, Henry AL, Stott R, Miller CB, Espie CA Tags: J Sleep Res Source Type: research

The Epworth sleepiness scale: Reliably unreliable in a sleep clinic population.
The objective of this study was to evaluate the reliability of this instrument among adult patients recruited from a public hospital sleep clinic in Sydney, Australia. English-speaking participants self-completed the Epworth Sleepiness Scale on two occasions, at the specialist clinic visit and on the night of diagnostic polysomnography. Of the 108 participants included in the study, the majority were male (64%) and the mean age was 51 years. The median retest interval was 64 days. The primary outcome of test-retest reliability as measured using the intraclass correlation coefficient was 0.73 (95% confidence inter...
Source: Journal of Sleep Research - February 28, 2020 Category: Sleep Medicine Authors: Lee JL, Chung Y, Waters E, Vedam H Tags: J Sleep Res Source Type: research

Sleep and resting-state functional magnetic resonance imaging connectivity in middle-aged adults and the elderly: A population-based study.
Abstract Sleep problems increase with ageing. Increasing evidence suggests that sleep problems are not only a consequence of age-related processes, but may independently contribute to developing vascular or neurodegenerative brain disease. Yet, it remains unclear what mechanisms underlie the impact sleep problems may have on brain health in the general middle-aged and elderly population. Here, we studied sleep's relation to brain functioning in 621 participants (median age 62 years, 55% women) from the population-based Rotterdam Study. We investigated cross-sectional associations of polysomnographic and subje...
Source: Journal of Sleep Research - February 26, 2020 Category: Sleep Medicine Authors: Lysen TS, Zonneveld HI, Muetzel RL, Ikram MA, Luik AI, Vernooij MW, Tiemeier H Tags: J Sleep Res Source Type: research

The use and effectiveness of adaptive servo ventilation in central sleep apnea: a study of consecutive sleep clinic patients.
This study shows the effectiveness of adaptive servo ventilation in treating patients with central sleep apnea, irrespective of a predisposing factor, as assessed during a 4-week treatment trial. Results show that adaptive servo ventilation was effective and superior to continuous positive airway pressure in controlling central sleep apnea and improving symptoms. Only a small proportion of these patients had comorbid heart failure. Early treatment with adaptive servo ventilation may improve long-term adherence to therapy. These findings highlight the utility of adaptive servo ventilation in the management of central sleep ...
Source: Journal of Sleep Research - February 22, 2020 Category: Sleep Medicine Authors: Huseini T, McArdle N, Jasper E, Kurmagadda S, Douglas J, King S, Sturdy G, Singh B Tags: J Sleep Res Source Type: research

Exploring scoring methods for research studies: Accuracy and variability of visual and automated sleep scoring.
Abstract Sleep studies face new challenges in terms of data, objectives and metrics. This requires reappraising the adequacy of existing analysis methods, including scoring methods. Visual and automatic sleep scoring of healthy individuals were compared in terms of reliability (i.e., accuracy and stability) to find a scoring method capable of giving access to the actual data variability without adding exogenous variability. A first dataset (DS1, four recordings) scored by six experts plus an autoscoring algorithm was used to characterize inter-scoring variability. A second dataset (DS2, 88 recordings) scored a few...
Source: Journal of Sleep Research - February 18, 2020 Category: Sleep Medicine Authors: Berthomier C, Muto V, Schmidt C, Vandewalle G, Jaspar M, Devillers J, Gaggioni G, Chellappa SL, Meyer C, Phillips C, Salmon E, Berthomier P, Prado J, Benoit O, Bouet R, Brandewinder M, Mattout J, Maquet P Tags: J Sleep Res Source Type: research

Repeated afternoon sleep recordings indicate first-night-effect-like adaptation process in family dogs.
acute;csi M Abstract The importance of dogs (Canis familiaris) in sleep research is primarily based on their comparability with humans. In spite of numerous differences, dogs' comparable sleep pattern, as well as several phenotypic similarities on both the behavioural and neural levels, make this species a most feasible model in many respects. Our aim was to investigate whether the so-called first-night effect, which in humans manifests as a marked macrostructure difference between the first and second sleep occasions, can be observed in family dogs. We used a non-invasive polysomnographic method to monitor and co...
Source: Journal of Sleep Research - February 17, 2020 Category: Sleep Medicine Authors: Reicher V, Kis A, Simor P, Bódizs R, Gombos F, Gácsi M Tags: J Sleep Res Source Type: research