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Drug: Melatonin

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Total 4647 results found since Jan 2013.

Melatonin reduces exo-endocytosis in mast cells, making it a useful therapeutic tool in inflammatory diseases
Ann Allergy Asthma Immunol. 2023 Aug 7:S1081-1206(23)00562-8. doi: 10.1016/j.anai.2023.07.025. Online ahead of print.NO ABSTRACTPMID:37557953 | DOI:10.1016/j.anai.2023.07.025
Source: Annals of Allergy, Asthma and Immunology - August 9, 2023 Category: Allergy & Immunology Authors: Mar ía Dolores Maldonado Mar ía Carmen Gutiérrez-Pérez Juan Antonio Flores Eva Ales Source Type: research

Retraction Note: Protective effects of melatonin against mitochondrial injury in a mouse model of multiple sclerosis
Exp Brain Res. 2023 Aug 7. doi: 10.1007/s00221-023-06681-y. Online ahead of print.NO ABSTRACTPMID:37548667 | DOI:10.1007/s00221-023-06681-y
Source: Brain Research - August 7, 2023 Category: Neurology Authors: Iraj Ragerdi Kashani Zahra Rajabi Mohammad Akbari Gholamreza Hassanzadeh Alireza Mohseni Mohammadtaha Kouchakinejad Eramsadati Kheirollah Rafiee Cordian Beyer Markus Kipp Adib Zendedel Source Type: research

Downregulation of PDCD4 through STAT3/ATF6/autophagy mediates MIF-induced PASMCs proliferation/migration and vascular remodeling
In conclusions, we demonstrate that MIF activates the STAT3/ATF6/autophagy cascade and then degrades PDCD4 leading to PASMCs proliferation/migration and pulmonary vascular remodeling, suggesting that intervention this axis might have potential value in management of PH.PMID:37549728 | DOI:10.1016/j.ejphar.2023.175968
Source: European Journal of Pharmacology - August 7, 2023 Category: Drugs & Pharmacology Authors: Limin Chai Qingting Wang Yan Wang Danyang Li Qianqian Zhang Yuqian Chen Jin Liu Huan Chen Yuanjie Qiu Nirui Shen Jian Wang Xinming Xie Manxiang Li Source Type: research

Retraction Note: Protective effects of melatonin against mitochondrial injury in a mouse model of multiple sclerosis
Exp Brain Res. 2023 Aug 7. doi: 10.1007/s00221-023-06681-y. Online ahead of print.NO ABSTRACTPMID:37548667 | DOI:10.1007/s00221-023-06681-y
Source: Experimental Brain Research - August 7, 2023 Category: Neuroscience Authors: Iraj Ragerdi Kashani Zahra Rajabi Mohammad Akbari Gholamreza Hassanzadeh Alireza Mohseni Mohammadtaha Kouchakinejad Eramsadati Kheirollah Rafiee Cordian Beyer Markus Kipp Adib Zendedel Source Type: research

Downregulation of PDCD4 through STAT3/ATF6/autophagy mediates MIF-induced PASMCs proliferation/migration and vascular remodeling
In conclusions, we demonstrate that MIF activates the STAT3/ATF6/autophagy cascade and then degrades PDCD4 leading to PASMCs proliferation/migration and pulmonary vascular remodeling, suggesting that intervention this axis might have potential value in management of PH.PMID:37549728 | DOI:10.1016/j.ejphar.2023.175968
Source: European Journal of Pharmacology - August 7, 2023 Category: Drugs & Pharmacology Authors: Limin Chai Qingting Wang Yan Wang Danyang Li Qianqian Zhang Yuqian Chen Jin Liu Huan Chen Yuanjie Qiu Nirui Shen Jian Wang Xinming Xie Manxiang Li Source Type: research

Insomnia Management: A Review and Update
J Fam Pract. 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620.ABSTRACTInsomnia is a distinct disorder that is common, yet underrecognized and undertreated in primary care. Treating insomnia has been shown to improve outcomes, including reduced risk of developing cardiovascular and mental health disorders. Insomnia is influenced by the brain's regulation of sleep and wake, which are mutually exclusive events. Insomnia should be treated as a distinct condition, even when occurring with a comorbid diagnosis such as depression or anxiety. Clinicians should implement a multimodal approach to insomnia management, including n...
Source: The Journal of Family Practice - August 7, 2023 Category: Practice Management Authors: David P Shaha Source Type: research

Downregulation of PDCD4 through STAT3/ATF6/autophagy mediates MIF-induced PASMCs proliferation/migration and vascular remodeling
In conclusions, we demonstrate that MIF activates the STAT3/ATF6/autophagy cascade and then degrades PDCD4 leading to PASMCs proliferation/migration and pulmonary vascular remodeling, suggesting that intervention this axis might have potential value in management of PH.PMID:37549728 | DOI:10.1016/j.ejphar.2023.175968
Source: European Journal of Pharmacology - August 7, 2023 Category: Drugs & Pharmacology Authors: Limin Chai Qingting Wang Yan Wang Danyang Li Qianqian Zhang Yuqian Chen Jin Liu Huan Chen Yuanjie Qiu Nirui Shen Jian Wang Xinming Xie Manxiang Li Source Type: research

Insomnia Management: A Review and Update
J Fam Pract. 2023 Jul;72(6 Suppl):S31-S36. doi: 10.12788/jfp.0620.ABSTRACTInsomnia is a distinct disorder that is common, yet underrecognized and undertreated in primary care. Treating insomnia has been shown to improve outcomes, including reduced risk of developing cardiovascular and mental health disorders. Insomnia is influenced by the brain's regulation of sleep and wake, which are mutually exclusive events. Insomnia should be treated as a distinct condition, even when occurring with a comorbid diagnosis such as depression or anxiety. Clinicians should implement a multimodal approach to insomnia management, including n...
Source: The Journal of Family Practice - August 7, 2023 Category: Practice Management Authors: David P Shaha Source Type: research