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Drug: Melatonin

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Total 4647 results found since Jan 2013.

The Efficacy of Ramelteon to Prevent Postoperative Delirium After General Anesthesia in the Elderly: A Double-Blind, Randomized, Placebo-Controlled Trial
CONCLUSION: There was no significant difference in the incidence of postoperative delirium between ramelteon and placebo after general anesthesia in elderly patients.PMID:37567839 | DOI:10.1016/j.jagp.2023.07.011
Source: Am J Geriatr Psychia... - August 11, 2023 Category: Geriatrics Authors: Mariko Kinouchi Takahiro Mihara Masataka Taguri Makoto Ogura Source Type: research

Pediatric hypnic headache: a systematic review
DiscussionFurther evaluation of the clinical features of HH in children is needed. The development of specific diagnostic criteria for pediatric cases could improve diagnostic rates and enhance the management of children with HH.
Source: Frontiers in Neurology - August 11, 2023 Category: Neurology Source Type: research

Toll-like Receptor 2-Melatonin Feedback Loop Regulates the Activation of Spinal NLRP3 Inflammasome in Morphine-Tolerant Rats
CONCLUSION: In this study, we directly demonstrate a TLR2-melatonin negative feedback loop regulating microglia and NLRP3 inflammasome activation during the development of morphine tolerance.PMID:37561258 | DOI:10.1007/s11064-023-03998-6
Source: Neurochemical Research - August 10, 2023 Category: Neuroscience Authors: Xiaoling Peng Jihong Wang Zheng Li Xiaoqian Jia Anqi Zhang Jie Ju Volker Eulenburg Feng Gao Source Type: research

Fucoidan/chitosan layered PLGA nanoparticles with melatonin loading for inducing intestinal absorption and addressing triple-negative breast cancer progression
This study demonstrates a favorable co-delivery system of melatonin and fucoidan to directly reduce drug resistance and metastasis in TNBC.PMID:37562466 | DOI:10.1016/j.ijbiomac.2023.126211
Source: International Journal of Biological Macromolecules - August 10, 2023 Category: Biochemistry Authors: Yu-Wei Yen Yi-Lin Lee Lu-Yi Yu Cheng-En Li Pei-Wei Shueng Hsin-Cheng Chiu Chun-Liang Lo Source Type: research

Toll-like Receptor 2-Melatonin Feedback Loop Regulates the Activation of Spinal NLRP3 Inflammasome in Morphine-Tolerant Rats
CONCLUSION: In this study, we directly demonstrate a TLR2-melatonin negative feedback loop regulating microglia and NLRP3 inflammasome activation during the development of morphine tolerance.PMID:37561258 | DOI:10.1007/s11064-023-03998-6
Source: Neurochemical Research - August 10, 2023 Category: Neuroscience Authors: Xiaoling Peng Jihong Wang Zheng Li Xiaoqian Jia Anqi Zhang Jie Ju Volker Eulenburg Feng Gao Source Type: research

Melatonin reduces exo-endocytosis in mast cells, making it a useful therapeutic tool in inflammatory diseases
Ann Allergy Asthma Immunol. 2023 Aug 7:S1081-1206(23)00562-8. doi: 10.1016/j.anai.2023.07.025. Online ahead of print.NO ABSTRACTPMID:37557953 | DOI:10.1016/j.anai.2023.07.025
Source: Annals of Allergy, Asthma and Immunology - August 9, 2023 Category: Allergy & Immunology Authors: Mar ía Dolores Maldonado Mar ía Carmen Gutiérrez-Pérez Juan Antonio Flores Eva Ales Source Type: research