Na+-K+-ATPase and nka genes in spotted sea bass (Lateolabrax maculatus) and their involvement in salinity adaptation
Publication date: Available online 23 May 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Xiaoyan Zhang, Haishen Wen, Xin Qi, Kaiqiang Zhang, Yang Liu, Hongying Fan, Peng Yu, Yuan Tian, Yun LiAbstractEuryhaline teleosts can survive in a wide salinity range via alteration of the molecular mechanisms to maintain internal ionic and osmotic balance in osmoregulatory organs such as gill,kidney and intestine. Na+/K+-ATPase (NKA), plays a crucial role in sustaining intracellular homeostasis and is characterized by association of multiple isoforms of α- and &beta...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 25, 2019 Category: Biochemistry Source Type: research

The case for reporting PO2 (partial pressure of oxygen), in addition to DO (dissolved oxygen), in studies of aquatic systems
Publication date: Available online 16 May 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Gordon R. Ultsch, Frank G. NordlieAbstractIn this essay, we question the sole use of mg/L (ppm) and the term DO (dissolved oxygen) when referring to oxygen supply in water, and discuss reasons for also reporting the partial pressure of oxygen (PO2). Oxygen moves from water into organisms by diffusion only, and the rate and direction of diffusion is solely dependent upon partial pressure gradients, not concentration gradients. However, the amount of oxygen moved into an organ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 18, 2019 Category: Biochemistry Source Type: research

Isolation and characterization of abundantly-expressed cDNAs from the Harderian gland of the garter snake (Thamnophis sirtalis: Colubridae)
Publication date: Available online 14 May 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Carolyn S. Steglich, Michael E. Brown, Elaina M. Mitchell, Michelle Millen, Susan J. RehorekAbstractThe Harderian gland (HG) is an orbital structure whose proteinaceous secretions pass through the nasolacrimal duct to the vomeronasal organ (VNO). Though these three structures occur in many tetrapod vertebrates, the garter snake (Thamnophis sirtalis) is one of the few vertebrates in which the passage of the proteinaceous secretions have been experimentally shown. Secreted pro...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 15, 2019 Category: Biochemistry Source Type: research

Regulation of glyceraldehyde-3-phosphate dehydrogenase by hypoxia inducible factor 1 in the white shrimp Litopenaeus vannamei during hypoxia and reoxygenation
Publication date: Available online 14 May 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Laura Camacho-Jiménez, Lilia Leyva-Carrillo, Alma B. Peregrino-Uriarte, Jorge L. Duarte-Gutiérrez, Martin Tresguerres, Gloria Yepiz-PlascenciaAbstractHypoxia is a frequent source of stress in the estuarine habitat of the white shrimp Litopenaeus vannamei. During hypoxia, L. vannamei gill cells rely more heavily on anaerobic glycolysis to obtain ATP. This is mediated by transcriptional up-regulation of glycolytic enzymes including glyceraldehyde-3-phosphate dehy...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 15, 2019 Category: Biochemistry Source Type: research

Expression of messenger RNA encoding two cellular metabolic regulators, AMP-activated protein kinase (AMPK) and O-GlcNAc transferase (OGT), in channel catfish: Their tissue distribution and relationship with changes in food intake
This study examined the tissue distribution of AMPK and OGT mRNA and changes in their expression in response to changes in food intake in channel catfish. Expression of all AMPK subunit and OGT mRNA was detectable in the whole brain, liver, heart, spleen, white muscle, and kidney of channel catfish. The OGT mRNA was highly localized in the brain compared to other tissues. 28-day fasting increased hepatic expression of AMPK α1, β1, and OGT mRNA while refeeding fish for 14 days after the 14-day fast decreased their expression to the level similar to that of fish that were fed daily. No changes were noted in the ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 13, 2019 Category: Biochemistry Source Type: research

Oxidative stress in Pelophylax esculentus complex frogs in the wild during transition from aquatic to terrestrial life
This study highlights the importance of ROS and the AOS of anurans in response to different developmental and/or environmental pressures that individuals face.Graphical abstract (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 11, 2019 Category: Biochemistry Source Type: research

14-3-3 gene family in spotted sea bass (Lateolabrax maculatus): Genome-wide identification, phylogenetic analysis and expression profiles after salinity stress
In this study, we identified eleven 14-3-3 genes from the spotted sea bass (Lateolabrax maculatus) genome and transcriptomic databases and verified their identities by conducting phylogenetic, syntenic and gene structure analyses. The spotted sea bass 14-3-3 genes are highly conserved based on sequence alignment, conserved domains and motifs, and tertiary structural feature. Quantitative real-time polymerase chain reaction (qRT-PCR) analysis of 14-3-3 genes in gill of spotted sea bass under normal physiological conditions indicated that the expression level of 14-3-3 zeta was the highest among tested genes, followed by 14-...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 10, 2019 Category: Biochemistry Source Type: research

The combination of resveratrol and exercise enhances muscle growth characteristics in pacu (Piaractus mesopotamicus)
Publication date: Available online 8 May 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Rondinelle Artur Simões Salomão, Tassiana Gutierrez De Paula, Bruna Tereza Thomazini Zanella, Pedro Luis Pucci Figueiredo Carvalho, Bruno Oliveira da Silva Duran, Jéssica Silvino Valente, Bruno Evaristo de Almeida Fantinatti, Ana Angélica Fernandes, Margarida Maria Barros, Edson Assunção Mareco, Robson Francisco Carvalho, Vander Bruno dos Santos, Maeli Dal-Pai-SilvaAbstractPacu is a tropical fish with important value to aquaculture. D...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 10, 2019 Category: Biochemistry Source Type: research

Editorial Board
Publication date: July 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Volume 233Author(s): (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 8, 2019 Category: Biochemistry Source Type: research

Invited review: Quantifying proton exchange from chemical reactions - Implications for the biochemistry of metabolic acidosis
Publication date: Available online 6 May 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Robert A. RobergsAbstractGiven that the chemistry of lactate production disproves the existence of a lactic acidosis, there is a need to further reveal and explain the importance of the organic and computational chemistry of pH dependent competitive cation fractional (~) proton (H+) exchange (~H+e). An additional importance of this knowledge is that it could potentially contradict the assumption of the Stewart approach to the physico-chemical theory of acid-base balance. For ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 7, 2019 Category: Biochemistry Source Type: research

Tipping points of gastric pH regulation and energetics in the sea urchin larva exposed to CO2 -induced seawater acidification
Publication date: August 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Volume 234Author(s): Hae-Gyeong Lee, Meike Stumpp, Jia-Jiun Yan, Yung-Che Tseng, Sebastian Heinzel, Marian Yong-An HuAbstractSea urchin larvae reduce developmental rates accompanied by changes in their energy budget when exposed to acidified conditions. The necessity to maintain highly alkaline conditions in their digestive systems led to the hypothesis that gastric pH homeostasis is a key trait affecting larval energy budgets leading to distinct tipping points for growth and survival.To test this hy...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 7, 2019 Category: Biochemistry Source Type: research

UCN3 suppresses food intake in coordination with CCK and the CCK2R in Siberian sturgeon (Acipenser baerii)
This study indicates for the first time in fish that UCN3 may inhibit food intake in coordination with CCK and CCK2R.Graphical abstract (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - May 1, 2019 Category: Biochemistry Source Type: research

Comparative physiology investigations support a role for histidine-containing dipeptides in intracellular acid–base regulation of skeletal muscle
Publication date: Available online 25 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Eimear Dolan, Bryan Saunders, Roger Charles Harris, Jose Eduardo Pereira Wilken Bicudo, David John Bishop, Craig Sale, Bruno GualanoAbstractHistidine containing dipeptides (HCDs: carnosine, anserine and balenine) have numerous therapeutic and ergogenic properties, but there is a lack of consensus on the mechanistic pathways through which they function. Potential roles include intracellular buffering, neutralisation of reactive species, and calcium regulation. Comparative i...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 26, 2019 Category: Biochemistry Source Type: research

The interplay between ambient temperature and salt intake affects oxidative status and immune responses in a ubiquitous Neotropical passerine, the rufous-collared sparrow
In this study, we evaluated the interplay between ambient temperature and salinity of drinking water on energy budgets and physiological responses in adult Rufous-collared sparrow, Zonotrichia capensis, an omnivorous passerine that is ubiquitous in Chile and inhabits a wide range of environments. We acclimated birds to 30 days at two ambient temperatures (27 °C and 17 °C) and drinking water salinity (200 mM NaCl and fresh water) conditions. We evaluated: 1) the aerobic scope and the activities of mitochondrial metabolic enzymes, 2) osmoregulatory parameter, 3) the skin-swelling immune response to an antigen...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 23, 2019 Category: Biochemistry Source Type: research

Tipping points of gastric pH regulation and energetics in the sea urchin larva exposed to CO2 induced seawater acidification
Publication date: Available online 22 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Hae-Gyeong Lee, Meike Stumpp, Jia-Jiun Yan, Yung-Che Tseng, Sebastian Heinzel, Marian Yong-an HuAbstractSea urchin larvae reduce developmental rates accompanied by changes in their energy budget when exposed to acidified conditions. The necessity to maintain highly alkaline conditions in their digestive systems led to the hypothesis that gastric pH homeostasis is a key trait affecting larval energy budgets leading to distinct tipping points for growth and survival.To test ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 23, 2019 Category: Biochemistry Source Type: research

Experimental evolution of aerobic exercise performance and hematological traits in bank voles
Publication date: Available online 17 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Małgorzata M. Lipowska, Geoffrey Dheyongera, Edyta T. Sadowska, Paweł KotejaAbstractThe maximum rate of aerobic exercise metabolism (VO2max) is a trait informative from both medical and evolutionary perspective, and both the physiological mechanisms limiting its level and its evolution are subject to vivid debate. Both comparative analyses and studies on the effects of training or acclimation to aerobically-demanding conditions suggest a role of oxygen transport-related ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 19, 2019 Category: Biochemistry Source Type: research

Exploring relationships between cardiovascular activity and parental care behavior in nesting smallmouth bass: A field study using heart rate biologgers
Publication date: Available online 18 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Tanya S. Prystay, Michael J. Lawrence, Aaron J. Zolderdo, Jacob W. Brownscombe, Robert de Bruijn, Erika J. Eliason, Steven J. CookeAbstractResearch in a variety of vertebrate taxa has found that cardiac function is a major limiting factor in the ability of animals to cope with physiological challenges, and thus is suggested to play an important role in mediating fitness-related behaviors in the wild. Yet, there remains a paucity of empirical assessments of the relationship...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 19, 2019 Category: Biochemistry Source Type: research

Metabolic regulation by the PGC-1α and PGC-1β coactivators in larval zebrafish (Danio rerio)
Publication date: Available online 18 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Caleb Northam, Christophe M.R. LeMoineAbstractThe peroxisome proliferator activated receptor γ coactivator-1 (PGC-1) family is composed of three coactivators whose role in regulating mammalian bioenergetics regulation is clear, but is much less certain in other vertebrates. Current evidence suggests that in fish, PGC-1α and PGC-1β may exhibit much less redundancy in the control of fatty acid oxidation and mitochondrial biogenesis compared to mammals. To as...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 19, 2019 Category: Biochemistry Source Type: research

Long term effects of chronic prenatal exposure to hypercarbia on organ growth and cardiovascular responses to adrenaline and hypoxia in common snapping turtles
Publication date: Available online 18 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Renato Filogonio, Dane A. CrossleyAbstractReptilian embryos often face challenging environmental gas compositions during incubation, which may inflict long lasting effects in the individuals' physiological responses. These conditions can have a lasting effect on the animal into juvenile life as chronic prenatal exposure to hypercarbia results in enlarged hatchling organ size, higher growth rate and resting metabolic rate, although relatively smaller increment in metabolic ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 19, 2019 Category: Biochemistry Source Type: research

Molecular characterization of manganese superoxide dismutase (MnSOD) from sterlet Acipenser ruthenus and its responses to Aeromonas hydrophila challenge and hypoxia stress
Publication date: Available online 15 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Ai Sun, Hua Zhu, Xiaowen Wang, Qiaomu Hu, Zhaohui Tian, Hongxia HuAbstractA novel gene encoding the mitochondrial manganese superoxide dismutase from sterlet Acipenser ruthenus (Ar-MnSOD) was cloned. The full-length cDNA of MnSOD was of 1040 bp with a 672 bp open reading frame encoding 224 amino acids and the deduced amino acid sequence was located in mitochondria. Sequence comparison analysis showed that Ar-MnSOD was highly similar to MnSODs of invertebrates and verte...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 17, 2019 Category: Biochemistry Source Type: research

Rapid cold hardening and octopamine modulate chill tolerance in Locusta migratoria
Publication date: Available online 13 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Phinyaphat Srithiphaphirom, Sarah Lavallee, R. Meldrum RobertsonAbstractTemperature has profound effects on the neural function and behaviour of insects. When exposed to low temperature, chill-susceptible insects enter chill coma, a reversible state of neuromuscular paralysis. Despite the popularity of studying the effects of low temperature on insects, we know little about the physiological mechanisms controlling the entry to, and recovery from, chill coma. Spreading depo...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 14, 2019 Category: Biochemistry Source Type: research

The migration of docosahexenoic acid (DHA) to the developing ovary of female zebrafish (Danio rerio)
Publication date: Available online 9 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Yanhong Zhu, Qingsong Tan, Leisen Zhang, Junpeng Yao, Hai Zhou, Pengcheng Hu, Xufang Liang, Hong LiuAbstractFish selectively reserves docosahexenoic acid (DHA) in ovary during gonadal development. However, no direct proof supports this. The present study tried to elucidate the DHA migration to the developing ovary of female zebrafish. An injection study of 13C-labeled DHA for DHA tracing was conducted, and another injection study of unlabeled-DHA (DHA-injected group) and BS...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 10, 2019 Category: Biochemistry Source Type: research

Low-frequency vibration transmission and mechanosensory detection in the legs of cave crickets
Publication date: Available online 9 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Nataša Stritih Peljhan, Peter T. Rühr, Barbara Buh, Johannes StraußAbstractVibrational communication is common in insects and often includes signals with prominent frequency components below 200 Hz, but the sensory adaptations for their detection are scarcely investigated. We performed an integrative study of the subgenual organ complex in Troglophilus cave crickets (Orthoptera: Rhaphidophoridae), a mechanosensory system of three scolopidial organs in th...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 10, 2019 Category: Biochemistry Source Type: research

Twenty years of the ‘Preparation for Oxidative Stress’ (POS) theory: Ecophysiological advantages and molecular strategies
Publication date: Available online 10 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Maximiliano Giraud-Billoud, Georgina A. Rivera-Ingraham, Daniel C. Moreira, Thorsten Burmester, Alfredo Castro-Vazquez, Juan M. Carvajalino-Fernández, Alcir Dafre, Cuijuan Niu, Nelly Tremblay, Biswaranjan Paital, Rui Rosa, Janet M. Storey, Israel A. Vega, Wenyi Zhang, Gloria Yepiz-Plascencia, Tania Zenteno-Savin, Kenneth B. Storey, Marcelo Hermes-LimaAbstractFreezing, dehydration, salinity variations, hypoxia or anoxia are some of the environmental constraints that ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 10, 2019 Category: Biochemistry Source Type: research

Editorial Board
Publication date: June 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Volume 232Author(s): (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 10, 2019 Category: Biochemistry Source Type: research

Exposure to artificial light at night increases innate immune activity during development in a precocial bird
Publication date: Available online 8 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Chandan Saini, Pierce Hutton, Sisi Gao, Richard K. Simpson, Mathieu Giraudeau, Tuul Sepp, Emily Webb, Kevin J. McGrawAbstractHumans have greatly altered Earth's night-time photic environment via the production of artificial light at night (ALAN; e.g. street lights, car traffic, billboards, lit buildings). ALAN is a problem of growing importance because it may significantly disrupt the seasonal and daily physiological rhythms and behaviors of animals. There has been consider...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 10, 2019 Category: Biochemistry Source Type: research

The acute and incremental thermal tolerance of Atlantic cod (Gadus morhua) families under normoxia and mild hypoxia
Publication date: July 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Volume 233Author(s): Fábio S. Zanuzzo, Jason A. Bailey, Amber F. Garber, Anthony K. GamperlAbstractGiven climate change projections, the limited ability of fish reared in sea-cages to behaviourally thermoregulate, and that thermal tolerance may be heritable, studies that examine family-related differences in upper thermal tolerance are quite relevant to the aquaculture industry. Thus, we investigated the upper thermal tolerance of 15 Atlantic cod (Gadus morhua L.) families by challenging them wi...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 5, 2019 Category: Biochemistry Source Type: research

Molecular and functional regionalization of bicarbonate secretion cascade in the intestine of the European sea bass (Dicentrarchus labrax)
In conclusion, intestinal HCO3– secretion has a functional region-dependent organization that was not reflected by the anterior-posterior regionalization on HCO3– secretion and expression profiles of chloride/water absorption related genes. (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 3, 2019 Category: Biochemistry Source Type: research

Endothermy in the smalleye opah (Lampris incognitus): A potential role for the uncoupling protein sarcolipin
Publication date: Available online 1 April 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Jens P.C. Franck, Eva Slight-Simcoe, Nicholas C. WegnerAbstractSarcolipin (SLN) is a small transmembrane protein that in mice has been shown to uncouple the calcium ATPase pump of the sarcoplasmic reticulum, resulting in heat production. Mice up-regulate expression of SLN in response to cold challenge. This thermoregulatory mechanism is characterized as non-shivering muscle-based thermogenesis (NST). The current study was conducted to determine if the endothermic fish speci...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - April 3, 2019 Category: Biochemistry Source Type: research

A pilot study to elucidate effects of artificial selection by size on the zebrafish (Danio rerio) fast skeletal muscle transcriptome.
In this study, we analysed the fast skeletal muscle of the zebrafish from selected lineages generated by Amaral and Johnston, 2012a, and investigated muscle fibre composition and used RNAseq to study the effects on fast skeletal muscle global gene expression, SV abundance and different retention of SNPs to better understand the molecular mechanisms behind muscle growth as a product of artificial selection.MethodsFish size selection.Animals from the large (L) and small (S) zebrafish were obtained from the lines previously generated by Amaral and Johnston, 2012a. Briefly, wild zebrafish were obtained from Mymensingh, Banglad...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 30, 2019 Category: Biochemistry Source Type: research

Dopamine binding directly up-regulates (Na+, K+)-ATPase activity in the gills of the freshwater shrimp Macrobrachium amazonicum
We examined the effects of exogenous dopamine on gill (Na+, K+)-ATPase activity in vitro in microsomal preparations from juvenile or adult freshwater shrimp, Macrobrachium amazonicum. Dopamine had no effect on enzyme activity in juveniles but stimulated activity in adult shrimp gills by ≈35%. Stimulation of the gill (Na+, K+)-ATPase in adult shrimps by 100 mmol L−1 dopamine was characterized kinetically by varying ATP, MgATP, and Na+ and K+ concentrations, together with inhibition by ouabain. Dopamine stimulated ATP hydrolysis by ≈40% obeying Michaelis-Menten kinetics, reaching VM = 190.5 &plusm...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 30, 2019 Category: Biochemistry Source Type: research

The acute and incremental thermal tolerance of cod (Gadus morhua) families under normoxia and mild hypoxia
Publication date: Available online 28 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Fábio S. Zanuzzo, Jason A. Bailey, Amber F. Garber, Anthony K. GamperlAbstractGiven climate change projections, the limited ability of fish reared in sea-cages to behaviourally thermoregulate, and that thermal tolerance may be heritable, studies that examine family-related differences in upper thermal tolerance are quite relevant to the aquaculture industry. Thus, we investigated the upper thermal tolerance of 15 Atlantic cod (Gadus morhua L.) families by challengin...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 30, 2019 Category: Biochemistry Source Type: research

Heterogeneous bioapatite carbonation in western painted turtles is unchanged after anoxia
Publication date: Available online 28 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Sarah W. Keenan, Jill D. Pasteris, Alian Wang, Daniel E. WarrenAbstractAdsorbed and structurally incorporated carbonate in bioapatite, the primary mineral phase of bone, is observed across vertebrates, typically at 2–8 wt%, and supports critical physiological and biochemical functions. Several turtle species contain elevated bone-associated carbonate, a property linked to pH buffering and overwintering survival. Prior studies of turtle bone utilized bulk analyses, ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 30, 2019 Category: Biochemistry Source Type: research

Membrane-initiated cortisol action modulates early pyruvate dehydrogenase kinase 2 (pdk2) expression in fish skeletal muscle
Publication date: Available online 28 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Jorge E. Aedo, Rodrigo Zuloaga, Sebastián Boltaña, Alfredo Molina, Juan Antonio ValdésAbstractCortisol is the main glucocorticoid hormone in teleosts involved in the regulation of metabolic adjustments under both normal and stressful physiological conditions. In the skeletal muscle, cortisol modulates the energetic metabolism promoting the mobilization of glucose and other energetic substrates to overcome the stress stimulus. The effects of cortisol-me...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 30, 2019 Category: Biochemistry Source Type: research

Distribution and properties of cardiac and pulmonary β-adrenergic receptors in corn snakes (Pantherophis guttatus) and Boa constrictor (Boa constrictor)
Publication date: Available online 28 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Getu Abraham, Sandra Hoffmann, Ina Hochheim, Michael PeesAbstractThe aim of the present study was to characterize β-adrenergic receptors in the snake heart and lung of corn and Boa constrictor snakes. The β-adrenergic receptor binding sites were studied in purified heart and lung membranes using the specific β-adrenergic receptor antagonist [125J]-iodocyanopindolol (ICYP) and subtypes using selective β1-adrenergic receptor antagonist CGP-20712A and sele...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 30, 2019 Category: Biochemistry Source Type: research

The central nervous system and muscular system play different roles for chill coma onset and recovery in insects
Publication date: Available online 22 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Mads Kuhlmann Andersen, Johannes OvergaardAbstractWhen insects are cooled, they initially lose their ability to perform coordinated movements at their critical thermal minima (CTmin). At a slightly lower temperature, they enter a state of complete paralysis (chill coma onset temperature - CCO) and if they are returned to permissive temperatures they regain function after a recovery period which is termed chill coma recovery time (CCRT). These three phenotypes (CTmin, CCO, ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 24, 2019 Category: Biochemistry Source Type: research

Survival rates and physiological recovery responses in the lesser-spotted catshark (Scyliorhinus canicula) after bottom-trawling
Publication date: Available online 21 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): C. Barragán-Méndez, I. Ruiz-Jarabo, J. Fuentes, J.M. Mancera, I. SobrinoAbstractIn 2019, Europe will adopt a no-discards policy in fisheries. This entails the landing of captured species unless strong evidence is provided supporting their survival and recovery after fishing. Thus, research on this topic is gaining momentum. Bottom-trawling, as a non-selective fishing method, is characterized by a high proportion of discards including vulnerable key species, s...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 22, 2019 Category: Biochemistry Source Type: research

Glucose regulates protein turnover and growth-related mechanisms in rainbow trout myogenic precursor cells
Publication date: Available online 21 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): M.N. Latimer, R.M. Reid, P.R. Biga, B.M. ClevelandAbstractRainbow trout are considered glucose intolerant because they are poor utilizers of glucose, despite having functional insulin receptors and glucose transporters. Following high carbohydrate meals, rainbow trout are persistently hyperglycemic, which is likely due to low glucose utilization in peripheral tissues including the muscle. Also, rainbow trout myogenic precursor cells (MPCs) treated in vitro with insulin and...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 21, 2019 Category: Biochemistry Source Type: research

Anorexigenic effects of mesotocin in chicks are genetic background-dependent and are associated with changes in the paraventricular nucleus and lateral hypothalamus
In conclusion, MT induced anorexia and hyperthermia and reduced water intake. MT was associated with activation of the PVN and LH and differences in the mRNA abundance of some appetite-associated factors, thus implicating these nuclei and several signaling pathways in the effects observed. (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 16, 2019 Category: Biochemistry Source Type: research

A long-term growth hormone treatment stimulates growth and lipolysis in gilthead sea bream juveniles
Publication date: Available online 15 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Emilio J. Vélez, Miquel Perelló-Amorós, Esmail Lutfi, Sheida Azizi, Encarnación Capilla, Isabel Navarro, Jaume Pérez-Sánchez, Josep A. Calduch-Giner, Josefina Blasco, Jaume Fernández-Borràs, Joaquim GutiérrezAbstractThe enhancement of the endocrine growth hormone (GH)/insulin-like growth factor I (IGF-I) system by the treatment with a sustained release formulation of a recombinant bovine GH (rBGH), is a good st...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 16, 2019 Category: Biochemistry Source Type: research

Termination of puberty in out-of-season male Atlantic salmon smolts
Publication date: Available online 15 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Thomas W.K. Fraser, Per Gunnar Fjelldal, Rüdiger W. Schulz, Birgitta Norberg, Tom J. HansenAbstractEnvironmental conditions are known to contribute to the phenotypic plasticity in the age of sexual maturation of Atlantic salmon (Salmo salar). Here, we report on an observation of out-of-season male Atlantic salmon initiating puberty as pre-smolts (jacks) but failing to complete maturation as post-smolts. Jacks were identified based on elevated plasma 11-ketotestosteron...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 16, 2019 Category: Biochemistry Source Type: research

Editorial Board
Publication date: May 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative Physiology, Volume 231Author(s): (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 16, 2019 Category: Biochemistry Source Type: research

The effects of salinity and hypoxia exposure on oxygen consumption, ventilation, diffusive water exchange and ionoregulation in the Pacific hagfish (Eptatretus stoutii)
Publication date: Available online 13 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Marina Giacomin, Giorgi Dal Pont, Junho Eom, Patricia M. Schulte, Chris M. WoodAbstractHagfishes (Class: Myxini) are marine jawless craniate fishes that are widely considered to be osmoconformers whose plasma [Na+], [Cl−] and osmolality closely resemble that of sea water, although they have the ability to regulate plasma [Ca2+] and [Mg2+] below seawater levels. We investigated the responses of Pacific hagfish to changes in respiratory and ionoregulatory demands impos...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 15, 2019 Category: Biochemistry Source Type: research

Isolation and sex steroid effects on the expression of the ATP-binding cassette transporter ABCB6 in Harderian glands of hamster (Mesocricetus auratus)
Publication date: Available online 14 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): L. Mares, F. Vilchis, B. Chávez, L. RamosGraphical abstract (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 15, 2019 Category: Biochemistry Source Type: research

Effect of water pH and calcium on ion balance in five fish species of the Mekong Delta
Publication date: Available online 12 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Yuzo R. Yanagitsuru, Charles R. Hewitt, Le Thi Hong Gam, Pham Phuong-Linh, Essie M. Rodgers, Tobias Wang, Mark Bayley, Do Thi Thanh Huong, Nguyen Thanh Phuong, Colin J. BraunerAbstractAcidic freshwater habitats disrupt ion-homeostasis in fishes, yet the often acidic waters of the Mekong host the second highest diversity of freshwater fish in the world. To investigate how five Mekong fish species tolerate water acidity, we measured: time to loss of equilibrium (LOE) at sust...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 13, 2019 Category: Biochemistry Source Type: research

Elucidation of the role of farnesoic acid O-methyltransferase (FAMeT) in the giant freshwater prawn, Macrobrachium rosenbergii: Possible functional correlation with ecdysteroid signaling
In this study, a full-length cDNA encoding a 278-amino-acid FAMeT protein (MrFAMeT) was characterized from the giant freshwater prawn, Macrobrachium rosenbergii. Bioinformatics analysis revealed a high degree of conservation of FAMeT among crustaceans and a close phylogenetic relationship between MrFAMeT and that of Scylla paramamosain. The prokaryotic expressed MrFAMeT could catalyze the conversion of FA to MF in a radiochemical assay. Expression analysis by quantitative real time reverse transcription polymerase chain reaction (qRT-PCR) demonstrated that MrFAMeT mRNA was highly expressed in the muscle and the hepatopancr...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 9, 2019 Category: Biochemistry Source Type: research

The effect of temperature acclimation on thermal tolerance, hypoxia tolerance and aerobic scope in two subspecies of sheepshead minnow; Cyprinodon variegatus variegatus and Cyprinodon variegatus hubbsi
Publication date: Available online 8 March 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Ellen H. Jung, Kevin V. Brix, Colin J. BraunerAbstractThe freshwater teleost Cyprinodon variegatus hubbsi (Cvh) diverged from its euryhaline relative Cyprinodon variegatus variegatus (Cvv) ~150 kya and these subspecies are physiologically distinct in their osmoregulatory capabilities. Cvv inhabits intertidal estuaries and saltwater marshes along the Gulf of Mexico and Atlantic coast, where they experience a broad temperature range from −1.9 to 43 °C and freque...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - March 9, 2019 Category: Biochemistry Source Type: research

Molecular cloning and characterization of secretogranin II in the catfish Heteropneustes fossilis: Sex and seasonal brain regional variations and its gonadotropin regulation
Publication date: Available online 25 February 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Sandhya Sharma, Radha ChaubeAbstractSecretoneurin (SN) is a novel functional peptide derived from secretogranin II, a protein belonging to the class of chromogranins. Catfish Heteropneustes fossilis is an economically important species of the Asian subcontinent and holds an important place in reproductive physiology study. In the present study, the full-length cDNA encoding secretogranin IIb (SgIIb) was cloned from the brain of catfish H. fossilis. Sequence analysis sho...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - February 26, 2019 Category: Biochemistry Source Type: research

Impact of dietary starch on extrahepatic tissue lipid metabolism in farmed European (Dicentrarchus labrax) and Asian seabass (Lates calcarifer)
This study consolidated the use of 2H2O as tracer for fish lipid metabolism in different tissues, under different dietary conditions and suitable to use in different fish models. (Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology)
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - February 26, 2019 Category: Biochemistry Source Type: research

Positive correlation of gene expression between branchial FXYD proteins and Na+/K+-ATPase of euryhaline milkfish in response to hypoosmotic challenges
Publication date: Available online 25 February 2019Source: Comparative Biochemistry and Physiology Part A: Molecular & Integrative PhysiologyAuthor(s): Wen-Kai Yang, I. Chan Yang, Hsin-Ju Chuang, Tse-Lih Chao, Yau-Chung Hu, Wen-Yi Wu, Yu-Chun Wang, Cheng-Hao Tang, Tsung-Han LeeAbstractFXYD proteins are crucial regulators of Na+/K+-ATPase (NKA), which plays an important role in ion exchange by providing the driving force for other ion-transporting systems in the osmoregulatory organs, including the gills. In milkfish (Chanos chanos), gill NKA has been widely investigated and found to alter its expression (both mRNA and ...
Source: Comparative Biochemistry and Physiology Part A: Molecular and Integrative Physiology - February 26, 2019 Category: Biochemistry Source Type: research