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Drug: Polyethylene Glycol
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Total 2716 results found since Jan 2013.
Polysarcosine-Functionalized mRNA Lipid Nanoparticles Tailored for Immunotherapy
Pharmaceutics. 2023 Aug 1;15(8):2068. doi: 10.3390/pharmaceutics15082068.ABSTRACTLipid nanoparticles (LNPs) have gained great attention as carriers for mRNA-based therapeutics, finding applications in various indications, extending beyond their recent use in vaccines for infectious diseases. However, many aspects of LNP structure and their effects on efficacy are not well characterized. To further exploit the potential of mRNA therapeutics, better control of the relationship between LNP formulation composition with internal structure and transfection efficiency in vitro is necessary. We compared two well-established ioniza...
Source: Cancer Control - August 26, 2023 Category: Cancer & Oncology Authors: Christoph Wilhelmy Isabell Sofia Keil Lukas Uebbing Martin A Schroer Daniel Franke Thomas Nawroth Matthias Barz Ugur Sahin Heinrich Haas Mustafa Diken Peter Langguth Source Type: research
Thiolated Polymeric Hydrogels for Biomedical Applications: A review
In this study, different applications for polymers used in thiolated hydrogels, including dextran, gelatin, polyethylene glycol (PEG), cyclodextrins, chitosan, hyaluronic acid, alginate, poloxamer, polygalacturonic acid, pectin, carrageenan gum, arabinoxylan, carboxymethyl cellulose (CMC), gellan gum, and polyvinyl alcohol (PVA) are reviewed.PMID:37622704 | DOI:10.2174/1381612829666230825100859
Source: Current Pharmaceutical Design - August 25, 2023 Category: Drugs & Pharmacology Authors: Farhan Younas Muhammad Zaman Waqar Aman Umer Farooq Maria Abdul Ghafoor Raja Muhammad Wahab Amjad Source Type: research
Immobilization of Rhodococcus by encapsulation and entrapment: a green solution to bitter citrus by-products
Appl Microbiol Biotechnol. 2023 Aug 24. doi: 10.1007/s00253-023-12724-9. Online ahead of print.ABSTRACTDebittering of citrus by-products is required to obtain value-added compounds for application in the food industry (e.g., dietary fiber, bioactive compounds). In this work, the immobilization of Rhodococcus fascians cells by encapsulation in Ca-alginate hollow beads and entrapment in poly(vinyl alcohol)/polyethylene glycol (PVA/PEG) cryogels was studied as an alternative to chemical treatments for degrading the bitter compound limonin. Previously, the Rhodococcus strain was adapted using orange peel extract to increase it...
Source: Applied Microbiology and Biotechnology - August 24, 2023 Category: Microbiology Authors: Mar ía C Pilar-Izquierdo Mar ía López-Fouz Natividad Ortega Mar ía D Busto Source Type: research
Sialylation: An alternative to designing long-acting and targeted drug delivery system
Biomed Pharmacother. 2023 Aug 21;166:115353. doi: 10.1016/j.biopha.2023.115353. Online ahead of print.ABSTRACTLong-acting and specific targeting are two important properties of excellent drug delivery systems. Currently, the long-acting strategies based on polyethylene glycol (PEG) are controversial, and PEGylation is incapable of simultaneously possessing targeting ability. Thus, it is crucial to identify and develop approaches to produce long-acting and targeted drug delivery systems. Sialic acid (SA) is an endogenous, negatively charged, nine-carbon monosaccharide. SA not only mediates immune escape in the body but also...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - August 23, 2023 Category: Drugs & Pharmacology Authors: Qixiong Zhang Shanshan Li Rongsheng Tong Yuxuan Zhu Source Type: research
Efficient delivery of mesenchymal stem/stromal cells to injured liver by surface PEGylation
CONCLUSION: These results indicate that PEG modification to the surface of MSCs can suppress the lung entrapment of intravenously administered MSCs and improve their homing to the injured liver.PMID:37608303 | DOI:10.1186/s13287-023-03446-w
Source: Cell Research - August 23, 2023 Category: Cytology Authors: Yukiya Takayama Kosuke Kusamori Yuri Katsurada Shu Obana Shoko Itakura Makiya Nishikawa Source Type: research
Exploring the role of HaTIPs genes in enhancing drought tolerance in sunflower
CONCLUSION: Hence these genes can be utilized as potential target in improving water use efficiency and for further genetic manipulation for the development of drought tolerant sunflower. This study may further contribute to our better understanding regarding the precise role of HaTIPs through their spatial and temporal expression analysis and their application in sunflower drought stress responses.PMID:37606830 | DOI:10.1007/s11033-023-08679-9
Source: Mol Biol Cell - August 22, 2023 Category: Molecular Biology Authors: Tania Safdar Muhammad Hammad Nadeem Tahir Zulfiqar Ali Muhammad Habib Ur Rahman Source Type: research
Titanium dioxide nanoparticles improve element uptake, antioxidant properties, and essential oil productivity of Melissa officinalis L. seedlings under in vitro drought stress
Environ Sci Pollut Res Int. 2023 Aug 21. doi: 10.1007/s11356-023-29384-x. Online ahead of print.ABSTRACTIn vitro drought stress has a considerable impact on the mass production of active compounds in medicinal plants. Nevertheless, photosynthesis, nutrient uptake, and protein synthesis may be negatively affected by drought, which results in poor growth. Titanium dioxide nanoparticles (TiO2 NPs) have recently been shown to play an important role in increasing nutrient uptake, resistance to various environmental stresses, and better plant growth. Regarding the importance of pharmaceutical metabolites of Melissa officinalis L...
Source: Environmental Science and Pollution Research International - August 21, 2023 Category: Environmental Health Authors: Roya Razavizadeh Fatemeh Adabavazeh Zahra Mosayebi Source Type: research
