Filtered By:
Drug: Polyethylene Glycol
This page shows you your search results in order of date. This is page number 20.
Order by Relevance | Date
Total 2716 results found since Jan 2013.
Delivery mechanism of doxorubicin by PEG-DPPE micelles on membrane invasion by dynamic simulations
This study provides new theoretical insights into the mechanism of PEG-DPPE micelles in delivering drugs through membranes, which is of benefit for further optimization of PEGylated delivery systems.PMID:37278335 | DOI:10.1039/d2cp05946k
Source: Health Physics - June 6, 2023 Category: Physics Authors: Lina Zhao Meina Ren Yanjiao Wang Hailong An Fude Sun Source Type: research
Design, development, and in-vitro/in-vivo evaluation of Docetaxel-loaded PEGylated Solid Lipid Nanoparticles in Prostate Cancer Therapy
Eur J Pharm Biopharm. 2023 Jun 1:S0939-6411(23)00142-X. doi: 10.1016/j.ejpb.2023.05.020. Online ahead of print.ABSTRACTDocetaxel (DOC) is a potent anticancer molecule widely used to treat various cancers. However, its therapeutic efficacy as a potential anticancer agent has been limited owing to poor aqueous solubility, short circulation time, rapid reticuloendothelial system uptake, and high renal clearance, which consecutively showed poor bioavailability. In the present investigation, we developed polyethylene glycol (PEG) decorated solid lipid nanoparticles (SLN) using the solvent diffusion method to increase the biopha...
Source: European Journal of Pharmaceutics and Biopharmaceutics - June 3, 2023 Category: Drugs & Pharmacology Authors: Swati Korake C Bothiraja Atmaram Pawar Source Type: research
Ganoderenic acid D-loaded functionalized graphene oxide-based carrier for active targeting therapy of cervical carcinoma
Biomed Pharmacother. 2023 Jun 1;164:114947. doi: 10.1016/j.biopha.2023.114947. Online ahead of print.ABSTRACTGanoderenic acid D (GAD), extracted from the Chinese herb Ganoderma lucidum, was loaded onto a graphene oxide-polyethylene glycol-anti-epidermal growth factor receptor (GO-PEG-EGFR) carrier to develop a targeting antitumor nanocomposite (GO-PEG@GAD). The carrier was fabricated from PEG and anti-EGFR aptamer modified GO. Targeting was mediated by the grafted anti-EGFR aptamer, which targets the membrane of HeLa cells. Physicochemical properties were characterized by transmission electron microscopy, dynamic light sca...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 3, 2023 Category: Drugs & Pharmacology Authors: Jiahui Lu Anqiang Zhang Fuming Zhang Robert J Linhardt Zhihui Zhu Yanzi Yang Tinghuang Zhang Zhibin Lin Su Zhang Huajun Zhao Peilong Sun Source Type: research
Design, development, and in-vitro/in-vivo evaluation of Docetaxel-loaded PEGylated Solid Lipid Nanoparticles in Prostate Cancer Therapy
Eur J Pharm Biopharm. 2023 Jun 1:S0939-6411(23)00142-X. doi: 10.1016/j.ejpb.2023.05.020. Online ahead of print.ABSTRACTDocetaxel (DOC) is a potent anticancer molecule widely used to treat various cancers. However, its therapeutic efficacy as a potential anticancer agent has been limited owing to poor aqueous solubility, short circulation time, rapid reticuloendothelial system uptake, and high renal clearance, which consecutively showed poor bioavailability. In the present investigation, we developed polyethylene glycol (PEG) decorated solid lipid nanoparticles (SLN) using the solvent diffusion method to increase the biopha...
Source: European Journal of Pharmaceutics and Biopharmaceutics - June 3, 2023 Category: Drugs & Pharmacology Authors: Swati Korake C Bothiraja Atmaram Pawar Source Type: research
Multifunctional hydrogel wound dressing with rapid on-demand degradation property based on aliphatic polycarbonate and chitosan
Int J Biol Macromol. 2023 May 30:125138. doi: 10.1016/j.ijbiomac.2023.125138. Online ahead of print.ABSTRACTThe multifunctional hydrogel dressings are effective strategy to treat chronic wounds of diabetes. In addition, the ability of selective degradation on demand to change dressings could provide better patient compliance. Here, an injectable, self-healing hydrogel with rapid degradability on-demand is designed to promote the healing of diabetes wounds. The block copolymer formed by aldehyde modified aliphatic cyclic carbonate monomer with polyethylene glycol (MBP) and chitosan (CS) were crosslinked through the Schiff b...
Source: International Journal of Biological Macromolecules - June 1, 2023 Category: Biochemistry Authors: Qida Zong Xinxuan Peng Yan Ding Huiying Wu Chang Lu Jing Ye Wei Sun Jinwei Zhang Yinglei Zhai Source Type: research
Reversible organohydrogels based on dynamic hydrogen bonding among water, dimethyl sulfoxide, and polyethylene glycol
Chem Commun (Camb). 2023 Jun 1. doi: 10.1039/d3cc02233a. Online ahead of print.ABSTRACTFacile gelation and degelation have been achieved by dynamic hydrogen bonding among dimethyl sulfoxide, water, and polyethylene glycol to prepare anti-freezing, drying-resistant, strongly thixotropic, and water-sensitive organohydrogels that are significant for biomaterial protection and storage.PMID:37261726 | DOI:10.1039/d3cc02233a
Source: Chemical Communications - June 1, 2023 Category: Chemistry Authors: Qinbo Jiang Meiyu Chen Zeyu Qin Jiawen Li Hui Zhang Source Type: research
Understanding the ultrasound field of high viscosity mixtures: Experimental and numerical investigation of a lab scale batch reactor
Ultrason Sonochem. 2023 May 23;97:106444. doi: 10.1016/j.ultsonch.2023.106444. Online ahead of print.ABSTRACTIn this work, mixtures of increasing viscosity (from 0.9 to ≈720 mPas) are sonicated directly using an ultrasonic horn at 30 kHz to investigate the effect of viscosity on the ultrasound field both from an experimental and numerical point of view. The viscosity of the mixtures is modified by preparing water-polyethylene glycol solutions. The impact of the higher viscosity on the acoustic pressure distribution is studied qualitatively and semi-quantitatively using sonochemiluminescence. The velocity of light scatter...
Source: Ultrasonics Sonochemistry - May 31, 2023 Category: Chemistry Authors: Ariana Bampouli Quinten Goris Jonas Van Olmen Serkan Solmaz Mohammed Noorul Hussain Georgios D Stefanidis Tom Van Gerven Source Type: research
Delivering Mechanism of Doxorubicin by the PEG-DPPE Micelles on Membrane Invasion by Dynamic Simulations
Phys. Chem. Chem. Phys., 2023, Accepted Manuscript DOI: 10.1039/D2CP05946K, PaperLina Zhao, Meina Ren, Yanjiao Wang, Hailong An, Fude Sun Exploiting the micelles of polyethylene glycol –dipalmitoylglycerophosphoethanolamine (PEG-DPPE) as drug delivery approach is of great promise for improving therapy targeting and half-lives of drugs. To optimize the micelle carriers, pending issues... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Phys. Chem. Chem. Phys. latest articles - May 29, 2023 Category: Chemistry Authors: Lina Zhao Source Type: research
