Filtered By:
Drug: Polyethylene Glycol
This page shows you your search results in order of date. This is page number 2.
Order by Relevance | Date
Total 2716 results found since Jan 2013.
Current advances and emerging trends in sustainable polyhydroxyalkanoate modification from organic waste streams for material applications
This study focuses on the development of sustainable, efficient, and cutting-edge methods, such as advanced bioprocess engineering, novel catalysts, and advances in materials science. Chemical techniques, such as epoxidation, oxidation, and esterification, have been employed for PHA functionalization, while enzymatic and microbial methods have indicated promise. PHB/polylactic acid blends with cellulose fibers showed improved tensile strength by 24.45-32.08 % and decreased water vapor and oxygen transmission rates while PHB/Polycaprolactone blends with a 1:1 ratio demonstrated an elongation at break four to six times highe...
Source: International Journal of Biological Macromolecules - September 11, 2023 Category: Biochemistry Authors: Nausheen Jaffur Gopalakrishnan Kumar Pratima Jeetah Seeram Ramakrishna Shashi Kant Bhatia Source Type: research
Unveiling pro-angiogenesis and drug delivery using dual-bio polymer with bio-ceramic based nanocomposite hydrogels
Chemosphere. 2023 Sep 8:140131. doi: 10.1016/j.chemosphere.2023.140131. Online ahead of print.ABSTRACTIn regenerative medicine, blood vessel development is of utmost importance as it enables the restoration of blood flow to tissues, and facilitate rapid vascularization in clinical tissue-engineered grafts. Herein, we fabricate the nanocomposite hydrogels from BG, alginate, Polyethylene glycol (PEG) and Dexamethasone (DEX) for the dual applications of drug delivery and angiogenesis assay. The hydrogels were fabricated through cross-linking approach and termed as alginate/PEG (A), alginate/PEG/clinophosinaite (AC), and algin...
Source: Chemosphere - September 10, 2023 Category: Chemistry Authors: K Elakkiya P Bargavi S Balakumar Source Type: research
Redefine the role of D- α-Tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein, multidrug resistance protein 1, and breast cancer resistance protein mediated cancer multidrug resistance
Eur J Pharm Sci. 2023 Sep 7:106579. doi: 10.1016/j.ejps.2023.106579. Online ahead of print.ABSTRACTCancer drug resistance is an ever-changing problem that most patients need to face in their later stages of treatment, especially the multidrug resistant (MDR) type. The drug efflux transporters, including P-glycoprotein (P-gp), multidrug resistance protein 1 (MRP1), and breast cancer resistance protein (BCRP), play the crucial roles in this sophisticated battle. In recent decades, researchers try to find potential inhibitors to impede the drug efflux function of above transporters. D-α-Tocopheryl polyethylene glycol 1000 su...
Source: European Journal of Pharmaceutical Sciences - September 9, 2023 Category: Drugs & Pharmacology Authors: Jing-Yi Chen Chieh-Ju Sung Ssu-Chi Chen Yi-Ping Hsiang Yung-Chia Hsu Yu-Ning Teng Source Type: research
Investigation on polyethylene glycol assisted solvothermal synthesis of CuCoO2 nanosheets for efficient oxygen evolution reaction
Dalton Trans., 2023, Accepted Manuscript DOI: 10.1039/D3DT02750C, PaperShiyu Ma, Jilin Bai, Li Sun, Lihong Zhao, Hao Tan, Lifeng Liu, Zhigang Peng, Xiujian Zhao, Dehua Xiong Water splitting to produce hydrogen is known as an effectively alleviate the energy crisis, but slow kinetics of oxygen evolution reaction (OER) has been seriously restricting the development of water... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Dalton Trans. latest articles - September 7, 2023 Category: Chemistry Authors: Shiyu Ma Source Type: research
Sustained neurotrophin-3 delivery from hyaluronic acid hydrogels for neural tissue regeneration
J Biomed Mater Res A. 2023 Sep 7. doi: 10.1002/jbm.a.37596. Online ahead of print.ABSTRACTThe goal of this work was to design a polymer-based platform capable of localized, long-term delivery of biologically active neurotropic factors using an affinity-based approach. Here, we synthesized hyaluronic acid-methylfuran (HA-mF) hydrogels that provide sustained, affinity-based release of neurotrophin-3 (NT-3), a growth factor that promotes axon growth for 28 days. A Diels-Alder crosslinking reaction between HA-mF and polyethylene glycol (PEG)-dimaleimide occurs within 15 min under physiological conditions, resulting in hydrogel...
Source: Biomed Res - September 7, 2023 Category: Research Authors: Pablo Ramos Ferrer Sangamithra Vardhan Shelly Sakiyama-Elbert Source Type: research
Crossover of surface waves and capillary-viscous-elastic transition in soft biomaterials detected by resonant acoustic rheometry
Biomaterials. 2023 Aug 30;302:122282. doi: 10.1016/j.biomaterials.2023.122282. Online ahead of print.ABSTRACTViscoelastic properties of hydrogels are important for their application in science and industry. However, rheological assessment of soft hydrogel biomaterials is challenging due to their complex, rapid, and often time-dependent behaviors. Resonant acoustic rheometry (RAR) is a newly developed technique capable of inducing and measuring resonant surface waves in samples in a non-contact fashion. By applying RAR at high temporal resolution during thrombin-induced fibrin gelation and ultraviolet-initiated polyethylene...
Source: Biomaterials - September 6, 2023 Category: Materials Science Authors: Eric C Hobson Weiping Li Nicole N Friend Andrew J Putnam Jan P Stegemann Cheri X Deng Source Type: research
Ferrocene/ β-cyclodextrin based supramolecular nanogels as theranostic systems
Biomed Pharmacother. 2023 Aug 31;166:115402. doi: 10.1016/j.biopha.2023.115402. Online ahead of print.ABSTRACTA supramolecular redox responsive nanogel (NG) with the ability to sense cancer cells and loaded with a releasing therapeutic agent was synthesized using hostguest interactions between polyethylene glycol-grafted-β-cyclodextrin and ferrocene boronic acid. Cyclic voltammetry matched with other spectroscopy and microscopy methods provided strong indications regarding host-guest interactions and formation of the NG. Moreover, the biological properties of the NG were evaluated using fluorescence silencing, confocal la...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 3, 2023 Category: Drugs & Pharmacology Authors: Khadijeh Soleimani Siamak Beyranvand Zeinab Souri Zainab Ahmadian Abdollah Yari Abbas Faghani Azim Shams Mohsen Adeli Source Type: research
PLGA and PEG based porous microparticles as vehicles for pulmonary Somatropin delivery
Eur J Pharm Biopharm. 2023 Sep 1:S0939-6411(23)00230-8. doi: 10.1016/j.ejpb.2023.08.017. Online ahead of print.ABSTRACTBreakthrough advances in protein therapeutics and sustained release systems continue to fuel innovation in novel, non-invasive polymeric platforms for delivery of biologicals. Despite the bench potential and proof-of-concept work, market analysis still shows biologicals to be predominantly injections. Characterized by insufficient secretion of growth hormone by the pituitary gland, growth hormone deficiency (GHD) is a rare disorder. Currently, chronic somatropin (r-hGH) replacement therapy is only availabl...
Source: European Journal of Pharmaceutics and Biopharmaceutics - September 3, 2023 Category: Drugs & Pharmacology Authors: Srushti Sodha Pardeep Gupta Source Type: research
Ferrocene/ β-cyclodextrin based supramolecular nanogels as theranostic systems
Biomed Pharmacother. 2023 Aug 31;166:115402. doi: 10.1016/j.biopha.2023.115402. Online ahead of print.ABSTRACTA supramolecular redox responsive nanogel (NG) with the ability to sense cancer cells and loaded with a releasing therapeutic agent was synthesized using hostguest interactions between polyethylene glycol-grafted-β-cyclodextrin and ferrocene boronic acid. Cyclic voltammetry matched with other spectroscopy and microscopy methods provided strong indications regarding host-guest interactions and formation of the NG. Moreover, the biological properties of the NG were evaluated using fluorescence silencing, confocal la...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - September 3, 2023 Category: Drugs & Pharmacology Authors: Khadijeh Soleimani Siamak Beyranvand Zeinab Souri Zainab Ahmadian Abdollah Yari Abbas Faghani Azim Shams Mohsen Adeli Source Type: research
