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Drug: Polyethylene Glycol

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Total 2716 results found since Jan 2013.

pH-influenced self-assembled stealth nanoscaffolds encapsulating memantine for treatment of Alzheimer's disease
In this study, polyethylene glycol (PEG)-coated poly D, L-lactic-co-glycolic acid (PLGA) nanostructures were prepared, as their self-assembling ability helps to penetrate the drug at disease sites with altered pH range (5.7-6.8) due to AD. Drug and polymer interaction studies by FTIR showed no interaction among them, and the thermal properties of drugs, polymers, and nanostructures tell us about their melting behaviour, thermal degradation, and glass transition temperatures. Characterization of prepared self-assembled nanoscaffolds signifies that the acquired properties such as size, structure, surface charges, zeta-potent...
Source: Journal of Biosciences - August 18, 2023 Category: Biomedical Science Authors: Varsha Rani Rinki Verma Krishan Kumar Ruchi Chawla Source Type: research

Characterization of a chlorine resistant and hydrophilic TiO < sub > 2 < /sub > /calcium alginate hydrogel filtration membrane used for protein purification maintaining protein structure
This study provides one method for the preparation of green and environmentally friendly membrane for protein purification.PMID:37591433 | DOI:10.1016/j.ijbiomac.2023.126367
Source: International Journal of Biological Macromolecules - August 17, 2023 Category: Biochemistry Authors: Ningning Gao Wenbin Xie Lijing Xu Qingping Xin Junkui Gao Junjun Shi Jin Zhong Wenxiong Shi Huiguo Wang Kongyin Zhao Ligang Lin Source Type: research

Clinical characteristics and immune profiles of patients with immune-mediated alopecia associated with COVID-19 vaccinations
CONCLUSIONS: Spike protein and excipients of COVID-19 vaccines could trigger T cell-mediated cytotoxicity, which contributes to the pathogenesis of immune-mediated alopecia associated with COVID-19 vaccines.PMID:37586672 | DOI:10.1016/j.clim.2023.109737
Source: Clinical Immunology - August 16, 2023 Category: Allergy & Immunology Authors: Chuang-Wei Wang Ming-Ying Wu Chun-Bing Chen Wei-Chen Lin Jennifer Wu Chun-Wei Lu Wei-Ti Chen Fang-Ying Wang Rosaline Chung-Yee Hui Min-Hui Chi Tsu-Man Chiu Ya-Ching Chang Jing Yi Lin Yang Yu-Wei Lin Wan-Ting Tsai Shuen-Iu Hung Wen-Hung Chung Source Type: research

Boron Nanoparticle-Enhanced Proton Therapy for Cancer Treatment
Nanomaterials (Basel). 2023 Jul 26;13(15):2167. doi: 10.3390/nano13152167.ABSTRACTProton therapy is one of the promising radiotherapy modalities for the treatment of deep-seated and unresectable tumors, and its efficiency can further be enhanced by using boron-containing substances. Here, we explore the use of elemental boron (B) nanoparticles (NPs) as sensitizers for proton therapy enhancement. Prepared by methods of pulsed laser ablation in water, the used B NPs had a mean size of 50 nm, while a subsequent functionalization of the NPs by polyethylene glycol improved their colloidal stability in buffers. Laser-synthesized...
Source: Cancer Control - August 12, 2023 Category: Cancer & Oncology Authors: Irina N Zavestovskaya Anton L Popov Danil D Kolmanovich Gleb V Tikhonowski Andrei I Pastukhov Maxim S Savinov Pavel V Shakhov Julia S Babkova Anton A Popov Ivan V Zelepukin Maria S Grigoryeva Alexander E Shemyakov Sergey M Klimentov Vladimir A Ryabov Para Source Type: research