Guidelines for fracture risk assessment and management of osteoporosis in postmenopausal women and men above the age of 50 in Qatar
ConclusionGuidance is provided to all physicians across the country who are involved in the care of patients with osteoporosis and fragility fractures. (Source: Archives of Osteoporosis)
Source: Archives of Osteoporosis - May 2, 2024 Category: Orthopaedics Source Type: research
Eliminate all risks: A call to reexamine the link between canine scabies and rheumatic heart disease
by Victoria J. Brookes, Caitlin E. Henning, Kate A. Worthing, Chris Degeling
Rheumatic heart disease (RHD) and acute rheumatic fever (ARF) disproportionately affect individuals in low-resource settings. ARF is attributed to an immune response to Group AStreptococcus (GAS) following GAS pharyngitis and potentially GAS impetigo in which infection can be initiated by scabies infestation. The burden of ARF and RHD in Aboriginal and Torres Strait Islander people in Australia is among the highest globally. Following recent calls to include dog management programs in ARF and RHD prevention programs, we believe it is timely to as...
Source: PLoS Neglected Tropical Diseases - May 2, 2024 Category: Tropical Medicine Authors: Victoria J. Brookes Source Type: research
Correlation between disease activity and patient-reported health-related quality of life in rheumatoid arthritis: a cross-sectional study
Conclusions
RA can have considerable impairment on patients’ HRQoL, both in terms of physical and psychosocial functioning. Given the strong correlation between clinical activity and HRQoL scores, and the fact that HRQoL can be an important clinical supplement. The EQ-5D-5L is probably the most appropriate generic measurement instrument for measuring HRQoL in RA patients. (Source: BMJ Open)
Source: BMJ Open - May 2, 2024 Category: General Medicine Authors: Feng, J., Yu, L., Fang, Y., Zhang, X., Li, S., Dou, L. Tags: Open access, Rheumatology Source Type: research
Relapsing polychondritis: clinical updates and new differential diagnoses
Nature Reviews Rheumatology, Published online: 02 May 2024; doi:10.1038/s41584-024-01113-9Relapsing polychondritis, a rare inflammatory disorder that affects cartilaginous structures, presents challenges in diagnosis owing to overlapping symptoms with other conditions. This Review provides a clinical update on relapsing polychondritis, emphasizing the importance of distinguishing this disease from similar conditions. (Source: Nature Reviews Rheumatology)
Source: Nature Reviews Rheumatology - May 2, 2024 Category: Rheumatology Authors: Philippe Mertz Nathalie Costedoat-Chalumeau Marcela A. Ferrada Guillaume Moulis Ars ène Mekinian Peter C. Grayson Laurent Arnaud Source Type: research
Burden evaluation and prediction of osteoarthritis and site-specific osteoarthritis coupled with attributable risk factors in China from 1990 to 2030
ConclusionsOA and site-specific OA remain huge public health challenges in China. The burden of OA and site-specific OA is increasing, especially among people over 50 years old. Health education, exercise, and removing modifiable risk factors contribute to alleviate the growing burden.Key Points• In China, the burden of osteoarthritisand site-specific osteoarthritis(hip, knee, hand, and others) as well as the Risk Factor (high body mass index) increased greatly from 1990 to 2019.• It is estimated that incident cases for OA and site-specific OA will continue to increase, despite that the ASR of OA incidence will decre...
Source: Clinical Rheumatology - May 2, 2024 Category: Rheumatology Source Type: research
Uncovering the link between inflammatory rheumatic diseases and male reproductive health: a perspective on male infertility and sexual dysfunction
AbstractInflammatory rheumatic diseases (IRDs) refer to a range of persistent disorders that have a major influence on several physiological systems. Although there is much evidence connecting IRDs to sexual dysfunction and fertility problems, research specifically focusing on male infertility in relation to these diseases is sparse. This review addresses the complicated connection between IRDs and male infertility, emphasising the physiological, psychological, and pharmacological aspects that influence reproductive health outcomes in men with rheumatic conditions. We explore the effects of IRDs and their treatments on man...
Source: Rheumatology International - May 2, 2024 Category: Rheumatology Source Type: research
Nurses ’ roles, interventions, and implications for management of rheumatic diseases
This article provides a comprehensive review of nurses ’ roles, interventions, and impacts in several rheumatic diseases, including rheumatoid arthritis, osteoarthritis, spondyloarthritis, gout, systemic lupus erythematosus, and polymyalgia rheumatica. It has been demonstrated that care under nursing supervision is effective and safe, with benefits in cluding disease management, quality of life, and treatment adherence. In addition, nurses play a crucial role in promoting health, educating patients, and administering biological disease-modifying anti-rheumatic drugs. The COVID-19 pandemic has highlighted the significance...
Source: Rheumatology International - May 2, 2024 Category: Rheumatology Source Type: research
Penicillin Allergy Testing and Delabeling for Patients Who Are Prescribed Penicillin: A Systematic Review for a World Health Organization Guideline
AbstractSecondary prevention with penicillin aims to prevent further episodes of acute rheumatic fever and subsequent development of rheumatic heart disease (RHD). Penicillin allergy, self-reported by 10% of the population, can affect secondary prevention programs. We aimed to assess the role for (i) routine penicillin allergy testing and the (ii) safety of penicillin allergy delabeling approaches in this context. We searched MEDLINE, Embase, CENTRAL, ClinicalTrials.gov, WHO ICTRP, ISRCTN, and CPCI-S to identify the relevant reports. We found 2419 records, but no studies addressed our initial question. Following advice fro...
Source: Clinical Reviews in Allergy and Immunology - May 2, 2024 Category: Allergy & Immunology Source Type: research
SGLT-2 inhibitors May Decrease Recurrent Gout Flares in Patients with Type 2 diabetes
Dr. Bernal
Clinical question: Do SGLT-2 inhibitors decrease gout flares in patients with type 2 diabetes and a known history of gout?
Background: Sodium–glucose cotransporter-2 inhibitors (SGLT-2 inhibitors) are known to decrease serum urate levels and the risk of incident gout. However, their role in secondary prevention of gout flares is unknown.
Study design: Propensity score–matched, new-user cohort study
Setting: British Columbia, Canada
Synopsis: Using a group of population-based, linked, administrative databases, the population of British Columbia was studied. 15,067 patients with gout and type 2 diabetes had f...
Source: The Hospitalist - May 1, 2024 Category: Hospital Management Authors: Ronda Whitaker Tags: Autoimmune Diseases In the Literature Pharmacology Rheumatology Source Type: research
Potential Efficacy of Janus Kinase Inhibitors in the Treatment of a Patient With Coexisting Peripheral and Axial Spondyloarthritis and Ulcerative Colitis
J Rheumatol. 2024 May 1:jrheum.2024-0055. doi: 10.3899/jrheum.2024-0055. Online ahead of print.ABSTRACTTumor necrosis factor inhibitors are effective and recommended in treating patients with coexisting spondyloarthritis (SpA) and ulcerative colitis (UC); however, the evidence of their superiority over other drugs is insufficient.1 Although Janus kinase inhibitors (JAKi) have shown effectiveness in treating UC and psoriatic arthritis, there are no reports of treating coexisting SpA and UC with JAKi monotherapy.PMID:38692666 | DOI:10.3899/jrheum.2024-0055 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Sho Ishigaki Nobuhiko Kajio Noritada Yoshikawa Hiroaki Taguchi Source Type: research
Interpersonal process of dyadic coping in rheumatoid arthritis: a perspective from the Australian Rheumatology Association Database (ARAD)
CONCLUSION: Participants and spouse's own views of supportive and negative dyadic coping they receive intimately affects their psychological distress and relationship quality. Also, having a partner with rheumatoid arthritis also seemed to impact the spouse especially when there was a negative dyadic coping pattern.PMID:38692667 | DOI:10.3899/jrheum.2023-0664 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Manasi M Mittinty Murthy N Mittinty Rachelle Buchbinder Marissa Lassere Vibhasha Chand Samuel Whittle Lyn March Catherine Hill Source Type: research
Sex-related differences in dispensation of rheumatic medications in older patients with inflammatory arthritis: A population-based study
CONCLUSION: This study did not identify any sex difference in use of DMARDs among older RA and PsA patients. Reasons for the higher use of opioids and NSAIDs among female RA patients warrants further research.PMID:38692668 | DOI:10.3899/jrheum.2023-1148 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Sanjana Tarannum Jessica Widdifield C Fangyun Wu Sindhu R Johnson Paula Rochon Lihi Eder Source Type: research
The Impact of Rheumatoid Arthritis on First Nations and How We Can Work With Communities to Prevent It
J Rheumatol. 2024 May 1:jrheum.2024-0369. doi: 10.3899/jrheum.2024-0369. Online ahead of print.ABSTRACTRheumatoid arthritis (RA) is prevalent in many Indigenous North American First Nations (FN) and tends to be seropositive, familial, and disabling, as well as associated with highly unfavorable outcomes such as early mortality. The risk of developing RA is based on a perfect storm of gene-environment interactions underpinning this risk. The gene-environment interactions include a high frequency of shared epitope encoding HLA alleles, particularly HLA-DRB1*1402, in the background population, and prevalent predisposing envir...
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Hani El-Gabalawy Source Type: research
Circulating interleukin 17A and other inflammatory proteins may predict cardiovascular disease in early rheumatoid arthritis
CONCLUSION: Circulating IL-17A at RA diagnosis predicted future CVD, although we cannot exclude that this finding is due to multiple testing. The association was independent of traditional CVD risk factors, and of ESR at the time of diagnosis. Furthermore, OPG may be a predictor of CVD. We also identified some novel potential biomarkers for CVD in RA.PMID:38692670 | DOI:10.3899/jrheum.2023-1078 (Source: Journal of Rheumatology)
Source: Journal of Rheumatology - May 1, 2024 Category: Rheumatology Authors: Emil Rydell Lennart T H Jacobsson Carl Turesson Source Type: research
Mortality, bone density and grip strength: lessons from the past and hope for the future?
CONCLUSION: We report strong relationships between grip strength and mortality compared with BMD. We hypothesize that this may reflect better recognition and treatment of low BMD in this cohort.PMID:38690291 | PMC:PMC11057971 | DOI:10.1093/rap/rkae046 (Source: Adv Data)
Source: Adv Data - May 1, 2024 Category: Epidemiology Authors: Leo D Westbury Faidra Laskou Harnish P Patel Cyrus Cooper Elaine M Dennison Source Type: research
