What do you call fluid collection around the heart?
Pericardial effusion is collection of fluid within the layers covering the heart. Pericardium is the covering of the heart. It has an inner layer and an outer layer. Fluid collects in between these layers in certain disease conditions and compresses the heart. If the amount of fluid is large or there is a rapid increase in the rate of fluid collection, the compression of the heart prevents its proper filling. An unfilled heart is not able to pump out blood well and the blood pressure falls. This serious condition is known as cardiac tamponade. Cardiac tamponade needs urgent removal of fluid from the pericardial cavity by n...
Source: Cardiophile MD - April 25, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

How Significant is First Degree Heart Block?
First degree heart block is an abnormality in the electrical conduction of the heart noted on the ECG, the recording of the electrical activity of the heart. It is not a block in the blood vessels of the heart which we are more familiar with. The waves on an ECG are P, QRS complex and the T wave. Normal interval between the onset of the P wave and the onset of QRS complex is up to one fifth of a second (0.2 seconds). When this interval is increased, it is called first degree heart block or first degree atrioventricular or AV block to be specific. Atria are the upper chambers of the heart and ventricles the lower chambers. ...
Source: Cardiophile MD - April 23, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Ballooning an obstructed prosthetic Aortic valve : Can be a real tense procedure!
A 76-year-old woman with a history of double valve replacement (Aortic and mitral valves) for rheumatic heart disease, presented with acute dyspnea after a switch from Warfarin to LMWH before a planned bone marrow biopsy. The investigations revealed a stuck aortic prosthetic valve ,that showed a prohibitive gradient of more than 50 mmhg. Since, she refused further surgery, a rare and risky effort was made to balloon dilate the prosthetic valve leaflet, though it is not a standard approved modality. It was decided to dilate the supero-lateral orifice and the central orifices by simultaneous kissing balloon. The results w...
Source: Dr.S.Venkatesan MD - April 10, 2024 Category: Cardiology Authors: dr s venkatesan Tags: Mitral prosthetic valve-Surgical tips and techniques prosthetic valve dysfunction prosthetic valves prosthetic valves -Technical issues Uncategorized balloon dilatation of prosthetic valve best review article on prosthetic valve obstruction Source Type: blogs

Echocardiographic evaluation in aortic regurgitation
Echocardiographic evaluation of aortic regurgitation, demonstrated through multiple images. Echocardiogram in parasternal long axis view shows dilated left ventricle, left atrium, aorta and a small portion of the right ventricle, which is usually the outflow region. Mitral valve leaflets seen in open position between the left ventricle and left atrium are thickened. The large aortic regurgitation jet can be seen as a mosaic jet in the left ventricular outflow tract anterior to the anterior mitral leaflet. A portion of the thickened aortic valve can be seen between the aorta and left ventricle. The AR jet is almost filling ...
Source: Cardiophile MD - April 10, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Fight Aging! Newsletter, April 8th 2024
In this study, we tested a stem cell secretome product, which contains extracellular vesicles and growth factors, cytoskeletal remodeling factors, and immunomodulatory factors. We examined the effects of 4 weeks of 2×/week unilateral intramuscular secretome injections (quadriceps) in ambulatory aged male C57BL/6 mice (22-24 months) compared to saline-injected aged-matched controls. Secretome delivery substantially increased whole-body lean mass and decreased fat mass, corresponding to higher myofiber cross-sectional area and smaller adipocyte size, respectively. Secretome-treated mice also had greater whole-bod...
Source: Fight Aging! - April 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Autoimmune disease flares: stress, grief, and management tips
Autoimmune diseases occur when the immune system mistakenly attacks healthy cells and tissues in the body. More than 80 recognized autoimmune diseases exist, including alopecia areata, rheumatoid arthritis, psoriasis, lupus, multiple sclerosis, celiac disease, scleroderma, and Raynaud’s. These conditions can cause a wide range of symptoms, making management crucial for maintaining a good quality of Read more… Autoimmune disease flares: stress, grief, and management tips originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 4, 2024 Category: General Medicine Authors: Tags: Conditions Rheumatology Source Type: blogs

Efferocytosis in the Context of Aging and Age-Related Disease
There is something of a tradition in the aging research community of writing reviews that attempt to summarize everything that is known of a single specific cellular behavior in the context of the panoply of cell and tissue dysfunction observed in aging. Today it is the turn of efferocytosis, the clearance of dying cells and their immediate debris by phagocytes such as macrophages of the innate immune system. It is fairly straightforward to mount an argument to suggest that more efficient efferocytosis is a good thing, as unwanted consequences attend the presence of lingering cell corpses cluttering up tissue. Like autopha...
Source: Fight Aging! - April 1, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Real pain deserves real treatment
When a patient comes to us and describes confusing symptoms that don’t seem to fit into any immediate category, we can see it in two different ways: as a challenge, we can rise to, a riddle to solve … or we can see it as an opportunity to denigrate the patient, to imply that they Read more… Real pain deserves real treatment originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 29, 2024 Category: General Medicine Authors: Tags: Conditions Rheumatology Source Type: blogs

Evaluation of JVP
Transcript of the video: Now we will discuss the basic principles of evaluation of jugular venous pressure and jugular venous pulse. These are assessed in the internal jugular vein and not in the external jugular vein. To revise the anatomy lessons, this is the external jugular vein and this is the internal jugular vein. Now, why we should not be looking at external jugual vein, though it is much easier to find out is that, in lower portion, it may be kinked so that it may not reflect the true right atrial pressure. The whole purpose of assessing the jugular venous pressure and pulse is that it reflects the right atrial pr...
Source: Cardiophile MD - March 21, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Navigating the health system with Ehlers-Danlos syndrome [PODCAST]
  Subscribe to The Podcast by KevinMD. Watch on YouTube. Catch up on old episodes! We sit down with Denise Reich, a patient advocate, to explore her journey of navigating the healthcare system with Ehlers-Danlos syndrome (EDS). Denise shares her experiences from the initial mention of EDS during an ophthalmology appointment to finally receiving a Read more… Navigating the health system with Ehlers-Danlos syndrome [PODCAST] originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - March 13, 2024 Category: General Medicine Authors: Tags: Podcast Rheumatology Source Type: blogs

Echocardiogram in Rheumatic Mitral and Aortic Regurgitation
Transcript of the video: This is an apical five chamber view and this is an apical four chamber view. You can see four chambers – RV, LV, RA, LA, and the transducer location is here. And this is five chamber because, in addition you are seeing the aorta also. Right atrium has not been labelled. In this view, you can see that mitral leaflets are thickened. This is anterior mitral leaflet, thickened, and in the closed position of mitral valve, when there should be no flow to the left atrium, you are seeing a jet, a mosaic jet, which has been traced out. Multi-coloured jet due to high velocity and turbulence. That is wh...
Source: Cardiophile MD - March 6, 2024 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Test results!
Hi everyone! Oh dear, I’ve been gone for quite some time, haven’t I? Life really does get in the way of plans sometimes. In this period, in addition to being super busy with a million other things, I’ve been focusing on getting my arthritic knee in shape. There’s no going back to the knee I had in my 20s, of course, but I can try at least to stop it from getting worse, mainly with physiotherapy. Okay, but enough about my knee….that’s not the reason I’ve written this post… Today I have some good news that I’d like to share with you…   Here’s the news: I just...
Source: Margaret's Corner - February 21, 2024 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll boswellia curcumin osteoarthritis Source Type: blogs

Ehlers-Danlos syndrome: Overcoming doctor bias for a life-changing diagnosis
“Do you have Ehlers-Danlos syndrome?” It wasn’t a question I expected during an ophthalmology appointment. It was, however, one I’d been asked before. Two other specialists had suggested I might have connective tissue issues, but nothing had ever come of it. All I could tell my ophthalmologist, then, was what I’d said before when it Read more… Ehlers-Danlos syndrome: Overcoming doctor bias for a life-changing diagnosis originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - February 21, 2024 Category: General Medicine Authors: Tags: Conditions Rheumatology Source Type: blogs

The Impact of US Abortion Policy on Rheumatology Clinical Practice: a Cross-Sectional Survey of Rheumatologists
Bonnie L. Bermas (University of Texas Southwestern), Irene Blanco (Northwestern University), Rosalind Ramsey-Goldman (Northwestern University), Ashira D. Blazer (Cornell University), et al., The Impact of US Abortion Policy on Rheumatology Clinical Practice: a Cross-Sectional Survey of Rheumatologists, Arthritis& Rheumatology... (Source: HealthLawProf Blog)
Source: HealthLawProf Blog - January 14, 2024 Category: Medical Law Authors: Katharine Van Tassel Source Type: blogs

Fight Aging! Newsletter, January 8th 2024
This study examined whether the local injection of the supernatant of activated PRP (saPRP) into the salivary gland (SG) could help prevent aging-induced SG dysfunction and explored the mechanisms responsible for the protective effects on the SG hypofunction. Human salivary gland epithelial cells (hSGEC) were treated with saPRP or PRP after senescence through irradiation. The significant proliferation of hSGEC was observed in saPRP treated group compared to irradiation only group and irradiation + PRP group. Cellular senescence, apoptosis, and inflammation were significantly reduced in the saPRP group. Th...
Source: Fight Aging! - January 7, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs