COVID-19 and renal allograft rejection: insight from controlled and non-controlled studies
CONCLUSION: In conclusion, the limited number of published controlled studies revealed no statistically significant association between COVID-19 infection and biopsy-proven rejection among KTRs. However, the broader analysis of non-controlled studies showed a variable rejection incidence with a pooled rejection rate of 11.8%. There is insufficient high-quality data to explore the association of COVID-19 infection and rejection.PMID:38627208 | DOI:10.1080/0886022X.2024.2336126 (Source: Renal Failure)
Source: Renal Failure - April 16, 2024 Category: Urology & Nephrology Authors: Ahmed Daoud Karim Soliman Maria Aurora Posadas Salas Genta Uehara Sakshi Vaishnav Wisit Cheungpasitporn Michael J Casey Source Type: research
The transcription factor HMGB2 indirectly regulates APRIL expression and Gd-IgA1 production in patients with IgA nephropathy
CONCLUSION: HMGB2 expression is greater in IgAN patients than in healthy controls; it promotes APRIL expression by interacting with HMGA1, thereby inducing Gd-IgA1 overexpression and leading to IgAN.PMID:38622929 | DOI:10.1080/0886022X.2024.2338931 (Source: Renal Failure)
Source: Renal Failure - April 16, 2024 Category: Urology & Nephrology Authors: Huijuan Tian Yaling Zhai Shuaigang Sun Wenhui Zhang Zhanzheng Zhao Source Type: research
Shen Shuai II recipe improves renal hypoxia to attenuate renal injury in 5/6 renal ablation/infarction rats and effect evaluation using blood oxygenation level-dependent functional magnetic resonance imaging
Conclusion: The degree of renal oxygenation reduction is correlated with the severity of renal injury in CKD. SSR can improve renal hypoxia to attenuate renal injury in 5/6 (A/I) rats of CKD.PMID:38622926 | DOI:10.1080/0886022X.2024.2338565 (Source: Renal Failure)
Source: Renal Failure - April 16, 2024 Category: Urology & Nephrology Authors: Yizeng Xu Fang Lu Meng Wang Lingchen Wang Chaoyang Ye Shuohui Yang Chen Wang Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Urological complications caused by inferior vena cava filters: a systematic review
CONCLUSIONS: Urological complications caused by IVC filters although rare, are likely underreported, require extensive workup, and pose surgical challenges. Due to their complex management, filter retrieval should be planned for as soon as feasible, and plans should be made as early as during the IVC filter implant. For those that do develop complications, clinical judgement must be exercised in management, and open surgical, endovascular or even conservative management strategies can be viable options and should be discussed in a multidisciplinary setting.PMID:38619204 | DOI:10.23736/S0392-9590.24.05041-7 (Source: International Angiology)
Source: International Angiology - April 15, 2024 Category: Cardiology Authors: Paul J Choi Mahmood Kabeil Pedro J Furtado Neves Nicos Labropoulos Ahsan Zil-E-Ali Faisal Aziz Emily A Malgor Rafael D Malgor Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Extracellular mitochondrial components as new biomarkers for lupus nephritis
This study has evaluated extracellular mitochondrial components, including cell-free mitochondria, and cell-free mitochondrial DNA as probable biomarkers of the degree of nephritis. Both showed a significant correlation with proteinuria and protein-creatinine ratio. Our study substantiates their usage as clinical biomarkers of nephritis upon their validation in a larger cohort of lupus nephritis patients and other forms of nephritis. Although the current data suggest using cell-free mitochondria as a biomarker of lupus nephritis is better than the cell-free mitochondrial DNA.PMID:38621786 | DOI:10.1177/09612033241247622 (Source: Lupus)
Source: Lupus - April 15, 2024 Category: Rheumatology Authors: Sharath Gowda Khushboo Rana Ankit Kumar Pradip Kumar Prajapati Namisha Patel Sapan Pandya Ratika Srivastava Source Type: research
Outcomes of oncological intended thoracic surgery after lung transplantation
CONCLUSIONS: Incidence of lung cancer is increased after LT. Follow-up care allows early diagnosis with a comparably high share of operable tumor stage. Cancer as well as postoperative complications were more likely after single lung transplantation (SLT). Postoperative morbidity and mortality are higher in this scarce group of patients and hence, warrants a centered and experienced interdisciplinary approach.PMID:38617760 | PMC:PMC11009586 | DOI:10.21037/jtd-23-1669 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Armin Frille Johannes Broschewitz Isabella Bettine Metelmann Matthias Steinert Maximilian von Laffert Hubert Wirtz Alexandra Wald Sebastian Kraemer Source Type: research
Impact of atrial fibrillation on 1-year outcome in patients with implantable cardioverter defibrillator or cardiac resynchronization therapy with defibrillator: results from the German DEVICE Registry
CONCLUSIONS: Our clinical data on an extended cohort of contemporary patients confirm the significant impact of AF, and its associated comorbidities, upon mortality and major adverse events after implantation of ICD/CRT.PMID:38617758 | PMC:PMC11009579 | DOI:10.21037/jtd-23-274 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Sebastian Feickert Niels Christian Ewertsen Julia K öbe Thomas Kleemann Joachim Jehle Jochen Senges Matthias Hochadel Dietrich Andresen Christoph Stellbrink Lars Eckardt Stefan Spitzer Johannes Brachmann H üseyin Ince Giuseppe D'Ancona Source Type: research
Urological complications caused by inferior vena cava filters: a systematic review
CONCLUSIONS: Urological complications caused by IVC filters although rare, are likely underreported, require extensive workup, and pose surgical challenges. Due to their complex management, filter retrieval should be planned for as soon as feasible, and plans should be made as early as during the IVC filter implant. For those that do develop complications, clinical judgement must be exercised in management, and open surgical, endovascular or even conservative management strategies can be viable options and should be discussed in a multidisciplinary setting.PMID:38619204 | DOI:10.23736/S0392-9590.24.05041-7 (Source: International Angiology)
Source: International Angiology - April 15, 2024 Category: Cardiology Authors: Paul J Choi Mahmood Kabeil Pedro J Furtado Neves Nicos Labropoulos Ahsan Zil-E-Ali Faisal Aziz Emily A Malgor Rafael D Malgor Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Outcomes of oncological intended thoracic surgery after lung transplantation
CONCLUSIONS: Incidence of lung cancer is increased after LT. Follow-up care allows early diagnosis with a comparably high share of operable tumor stage. Cancer as well as postoperative complications were more likely after single lung transplantation (SLT). Postoperative morbidity and mortality are higher in this scarce group of patients and hence, warrants a centered and experienced interdisciplinary approach.PMID:38617760 | PMC:PMC11009586 | DOI:10.21037/jtd-23-1669 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Armin Frille Johannes Broschewitz Isabella Bettine Metelmann Matthias Steinert Maximilian von Laffert Hubert Wirtz Alexandra Wald Sebastian Kraemer Source Type: research
