Kidney damage associated with COVID-19: from the acute to the chronic phase
Ren Fail. 2024 Dec;46(1):2316885. doi: 10.1080/0886022X.2024.2316885. Epub 2024 Apr 1.ABSTRACTSevere acute respiratory syndrome coronavirus-2 (SARS-COV-2) infection is well established as a systemic disease including kidney damage. The entry point into the renal cell remains the angiotensin-converting enzyme 2 (ACE-2) receptor and the spectrum of renal lesions is broad, with a clear predominance of structural and functional tubular lesions. The most common form of glomerular injury is collapsing glomerulopathy (CG), which is strongly associated with apolipoprotein L1(APOL-1) risk variants. These acute lesions, which are se...
Source: Renal Failure - April 1, 2024 Category: Urology & Nephrology Authors: Yannick Nlandu Elliot Koranteng Tannor Titilope Bafemika Jean-Robert Makulo Source Type: research
The use of ferumoxytol for high-resolution vascular imaging and troubleshooting for abdominal allografts
AbstractFerumoxytol is an ultrasmall superparamagnetic iron oxide which has been used as an off-label intravenous contrast agent for MRI. Unlike gadolinium-based contrast agents, ferumoxytol remains in the intravascular space with a long half-life of 14 –21 h. During the first several hours, it acts as a blood-pool agent and has minimal parenchymal enhancement. Studies have shown adequate intravascular signal for up to 72 h after initial contrast bolus. Ferumoxytol has been shown to be safe, even in patients with renal failure. Ferumoxytol has shown promise in a variety of clinical settings. The exquisite resolution en...
Source: Abdominal Imaging - April 1, 2024 Category: Radiology Source Type: research
Renal Recovery in LVAD Recipients Requiring Renal Replacement Therapy: Preoperative Renal Failure is Better
Purpose: The present study seeks to describe outcomes among patients who required acute renal replacement therapy (RRT) during admission before or after Left Ventricular Assist Device (LVAD) implant. (Source: The Journal of Heart and Lung Transplantation)
Source: The Journal of Heart and Lung Transplantation - April 1, 2024 Category: Transplant Surgery Authors: A. Cho, J. Perrier, , M. Hoque, B. Hauser, S. Hoffman, A. Elangovan, A. Goodman, I. Gosev, K. Wood Source Type: research
ELABELA-derived peptide ELA13 attenuates kidney fibrosis by inhibiting the Smad and ERK signaling pathways
In conclusion, ELA13 protected against kidney fibrosis through inhibiting the Smad and ERK signaling pathways and could thus be a promising candidate for anti-renal fibrosis treatment. (Source: Journal of Zhejiang University. Science. B.)
Source: Journal of Zhejiang University. Science. B. - April 1, 2024 Category: Universities & Medical Training Source Type: research
Maternal outcomes of pre-eclampsia with severe features and its determinants at Abebech Gobena Mothers and Childrens Health and Saint Peters Specialized Hospital, Addis Ababa, Ethiopia: a cross-sectional study
Conclusions
The prevalence of unfavourable maternal outcomes was high compared with other studies in Ethiopia. Maternal age, residence, occupation, blood pressure on admission and severe headache have shown a statistically significant association with unfavourable maternal outcomes. Socioeconomic development and early identification of severe signs and symptoms of pre-eclampsia are needed to reduce unfavourable outcomes. (Source: BMJ Open)
Source: BMJ Open - March 29, 2024 Category: General Medicine Authors: Tadese, M., Damesa, W. A., Solomon, G. S., Wakie, G. E., Tessema, S. D., Endale, A. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research
Impact of Genetic Polymorphisms in NF- ĸB2 and TRAF3 Genes on Response to Bortezomib-Based Therapy in Multiple Myeloma Patients
CONCLUSION: The study findings underscore a significant association between genetic polymorphisms and treatment response outcomes, suggesting their utility in prognostic determinations and clinical outcomes prediction in multiple myeloma patients.PMID:38546066 | DOI:10.31557/APJCP.2024.25.3.829 (Source: Asian Pacific Journal of Cancer Prevention)
Source: Asian Pacific Journal of Cancer Prevention - March 28, 2024 Category: Cancer & Oncology Authors: Nidhi Sood Abdoul Hamide Biswajit Dubashi Yadav Nisha Jayanthi Mathaiyan A K Munirajan Prasanth Ganesn Smita Kayal Source Type: research
