Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis

CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621

Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research