Changes in circulating markers of coagulation and fibrinolysis after endovascular repair of abdominal aortic aneurysms.
Authors: Kapetanios DM, Karkos CD, Papazoglou KO Abstract The presence of an abdominal aortic aneurysm (AAA) is associated with increased thrombin formation, fibrin turnover and fibrinolysis. The aim of this study was to review the relevant literature and summarize the evidence regarding the impact of endovascular repair on the circulating markers of coagulation and fibrinolysis post procedure. The main findings are that the increased thrombin activation, and formation, as well as fibrinolysis, in patients with AAA is exacerbated after endovascular repair in the short-term and the mid-term, implying that this may b...
Source: International Angiology - October 25, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Comparative analysis of five-year outcomes of lower extremity varicose vein therapy using monopolar and segmental radiofrequency ablation.
Authors: Woźniak W, Kielar M, Mlosek RK, Ciostek P Abstract BACKGROUND: To compare efficacy and safety of segmental and monopolar radiofrequency ablation in the management of lower extremity varicose veins. METHODS: 193 patients were treated with segmental RF ablation (Venefit; 97 subjects) or monopolar RF ablation (EVRF; 96 subjects) for lower extremity varicose veins in 2010-2012. A single extremity of each patient with isolated GSV or SSV insufficiency was enrolled. The differences between the two groups in demographic parameters, disease severity, treated veins, peri- and postoperative complications, and t...
Source: International Angiology - October 12, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Asymmetric dimethylarginine and angiogenesis: biological significance.
Authors: Wieczór AM, Wieczór R, Kulwas A, Rość D Abstract Competitive inhibition of endothelial nitric oxide synthase (eNOS) is the main biological effect of asymmetric dimethylarginine (ADMA) - the methylated derivative of L- arginine. The resulting low level of NO is becoming one of the elements of pathogenesis of numerous cardiovascular disorders, mainly related to atherosclerosis, but also other metabolic diseases including type 2 diabetes. It appears that a high level of ADMA is not only a marker of pathological conditions such as chronic kidney failure, but also a significant factor which dama...
Source: International Angiology - September 28, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Open repair of ruptured abdominal aortic aneurysm with associated horseshoe kidney.
CONCLUSIONS: Transperitoneal approach should be preferred during urgent OR of RAAA with concomitant HK. A supraceliac aortic cross clamping and the placement of occlusive Fogarty catheters into both iliac arteries are recommended for proximal and distal bleeding control. Preservation of accessory renal arteries that are larger than 3mm in diameter or supply more than 30% of renal parenchima is recommended. The division of the renal isthmus should be avoided if vascularized. It seems that renal arteries could be covered in emergency EVAR without any implications on postoperative kidney function, allowing broader aplication ...
Source: International Angiology - September 28, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Understanding lower leg volume measurements used in clinical studies focused on venous leg edema.
CONCLUSIONS: Patient heterogeneity and method of edema assessment impact clinical trial results. In particular, there are a number of error sources with several methods of assessment that can lead to variability in trial results. Consequently, pilot studies are required to validate new methods of edema assessment using innovative technologies. PMID: 30256052 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 28, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

The role of psychopathology in perceiving, reporting and treating intermittent claudication. A systematic review.
CONCLUSIONS: Mental disorders might influence the way in which the symptoms of the disease are reported, coped with, and treated. However, the results of the review preclude recommending a routine psychological examination as one of basic diagnostic procedures in patients with peripheral artery disease suffering from IC. PMID: 30203636 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 12, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Finite element analysis in symptomatic and asymptomatic abdominal aortic aneurysms for aortic disease risk stratification.
CONCLUSIONS: In conclusion, PWS was significantly higher in sAAA patients. Measuring PWS may help estimate the individual rupture risk in patients with AAA, but larger studies are needed to confirm our results. PMID: 30203637 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 12, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Renal function after abdominal aortic aneurysm repair in patients with baseline chronic renal insufficiency: open vs endovascular repair.
Authors: Marques De Marino P, Martinez Lopez I, Cernuda Artero I, Cabrero Fernandez M, Pla Sanchez F, Ucles Cabeza O, Serrano Hernando FJ Abstract BACKGROUND: The aim of this study is to analyse renal function impairment (RFI) after abdominalaortic aneurysm (AAA) repair in patients with preoperative chronic kidney disease (CKD). METHODS: Retrospective cohort study of patients with CKD undergoing elective AAA repair between 2008-2015, dividing the sample into two groups: open repair (OR) and endovascular repair (EVAR). The primary outcome was RFI defined by the RIFLE scale, studying Risk (1.5-fold increase in Cr...
Source: International Angiology - September 12, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Endovascular treatments for type Ib endoleaks after aorto-iliac aneurysms exclusion: mid-term results.
CONCLUSIONS: IbEL can be easily managed by endovascular means, typically with distal extensions with landing zones in the common or external iliac artery. Mid-term results are favourable, with no recurrent IbEL or reintervention. PMID: 30203639 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 12, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Treatment protocol on stasis edema in poorly mobile nursing home patients.
CONCLUSIONS: A Velcro® adjustable compression wrap (Circaid Juxtalite®) is efficient in reducing stasis edema in the elderly. Stabilization of the leg volume with the use of 15- 20 mmHg CS suggests that a high pressure to maintain results is not required to maintain results. PMID: 30203640 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 12, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

C0a and C0s patients: potential benefits for an unclear population.
Authors: Bissacco D, Oberto S PMID: 30203641 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 12, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Electrical calf muscle stimulation increases deep vein recanalization and reduces the incidence of recurrent deep vein thrombosis in patients with post-thrombotic syndrome and residual venous obstruction after completed 6 month of anticoagulation therapy.
Authors: Lobastov K, Ryzhkin V, Vorontsova A, Schastlivtsev I, Barinov V, Laberko L, Rodoman G Abstract BACKGROUND: The aim of this study was to assess the impact of electrical calf muscle stimulation (EMS) on clinical and ultrasound outcomes in patients with post-thrombotic syndrome (PTS) and residual venous obstruction (RVO). METHODS: This was a prospective, comparative, non-randomized clinical trial involving patients who had completed a standard 6-month course of anticoagulation therapy for a first episode of unprovoked femoro-popliteal DVT and had signs of RVO in the affected veins and PTS as shown by a Vi...
Source: International Angiology - September 1, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Internal iliac artery preservation strategies in the endovascular treatment of aortoiliac aneurysms.
CONCLUSIONS: When determining the appropriate hypogastric preservation strategy, several factors should be considered. Anatomic criteria, life-expectancy as well as physical and sexual activity are the most important criteria. Procedure complexity and cost should also be accounted for. PMID: 30001612 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - July 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Midterm results with drug coated balloons for SFA lesions in patients with CLI: comparison with conventional bypass surgery.
CONCLUSIONS: Drug coated balloon angioplasty yields comparable results to surgery in the setting of critical ischemia. The efficacy and the safety of DCB's in more complex lesions is to be investigated with randomized trials. PMID: 29963797 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - July 4, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Improvement of arterial wall phenotype in subjects at moderate cardiovascular risk induced by very low-dose fluvastatin/valsartan combination: a pilot study.
CONCLUSIONS: This pilot study revealed that intervention with low-flu/val importantly shifts the arterial wall phenotype in a lower risk direction. This improvement could be interpolated into clinical benefits that remain to be further studied. PMID: 29952159 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - June 30, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Heparin promotes recanalization of venous thrombotic occlusions.
Authors: Poredos P, Poredos P, Jezovnik MK Abstract Thrombosis is a consequence of disbalance between the procoagulant and fibrinolytic activity of blood and is frequently associated with chronic sequelae, which are the consequence of chronic occlusion of affected veins. Treatment of venous thrombosis should not be oriented in the prevention of thrombus progression and associated thromboembolic events, but also in stimulation of thrombolysis and recanalization of occluded veins, which are one of the most important preventive mechanisms of late sequelae, including post-thrombotic syndrome. The treatment of acute ven...
Source: International Angiology - June 28, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Epidemiology of peripheral artery disease in Europe: VAS Educational Paper.
Authors: Olinic DM, Spinu M, Olinic M, Homorodean C, Tataru DA, Liew A, Schernthaner GH, Stanek A, Fowkes G, Catalano M Abstract This paper reviews the current epidemiological data on peripheral artery disease (PAD) in Europe. Cardiovascular disease (CVD) burden is presented and PAD prevalence is discussed, as compared to coronary (CAD) and cerebrovascular (CeVD) diseases, in European Union (EU) countries and European continent countries. The article reviews PAD clinical manifestations, PAD diagnosis, risk factors for PAD incidence and progression, PAD prognosis and financial implications. CVD mortality is higher i...
Source: International Angiology - June 28, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Management of chronic venous disorders of the lower limbs. Guidelines According to Scientific Evidence. Part I.
Authors: Nicolaides A, Kakkos S, Baekgaard N, Comerota A, de Maesenner M, Eklof B, Giannoukas AD, Lugli M, Maleti O, Myers K, Nelzén O, Partsch H, Perrin M PMID: 29871479 [PubMed - in process] (Source: International Angiology)
Source: International Angiology - June 7, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Predictive factors of a poor outcome following revascularization for critical limb ischemia: implications for practice.
CONCLUSIONS: Certain preoperative variables can predict satisfactorily the short-term outcome after revascularization for CLI, although they are not sufficiently useful to identify the patient in whom revascularization can be clearly futile. Further research is needed to refine a predictive model suitable for decision-making. PMID: 29792018 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - May 25, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Predictors of long-term mortality following elective endovascular repair of abdominal aortic aneurysms.
CONCLUSIONS: Risk factors associated with long-term mortality following elective EVAR remain scarcely published. Several demographic, anatomical, cardiovascular, pulmonary and renal co-morbidities seem to have an association with long-term mortality. Critical scrutiny of clinical patient status remains fundamental for a fair health resources allocation. PMID: 29745617 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - May 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Medical management of stable peripheral artery disease (PAD) and the COMPASS trial. Are we improving medical care? Perspectives from a vascular standpoint.
Authors: Ramacciotti E, Castelli V, Walenga J, Fareed J PMID: 29745618 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - May 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

31P MR spectroscopy of patients with mild and serious lower limb ischemia.
CONCLUSIONS: A combination of rest and dynamic 31P MR spectroscopy can distinguish all three groups of subjects. On the other hand, examination at rest is sufficient for differentiation between patiens' groups and verification of severe ischemia. PMID: 29644834 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - April 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Risk assessment as a guide for the prevention of cancer-associated thromboembolism.
Authors: Al-Ogaili A, Fuentes HE, Tafur AJ, Caprini J Abstract Venous thromboembolism (VTE) is a major source of morbidity and mortality among patients diagnosed with cancer. In addition to an increased risk of VTE, patients with cancer are at higher risk of bleeding while receiving therapeutic anticoagulation. Aggressive and targeted thromboprophylaxis is a crucial practice to avoid the dreaded complications of VTE. Risk assessment models (RAM) are tools developed to identify high-risk patients in whom thromboprophylaxis is beneficial. This review describes the most validated VTE RAMs in patients with cancer. ...
Source: International Angiology - April 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Elevated extracellular nucleosomes and their relevance to inflammation in stage 5 chronic kidney disease.
Authors: Phan T, McMillan R, Skiadopoulos L, Walborn A, Hoppensteadt D, Fareed J, Bansal V Abstract BACKGROUND: Chronic kidney disease is a disorder characterized by a pro-inflammatory state that is associated with increased morbidity and mortality. Endogenous damage- associated molecular patterns, including nucleosomes, may contribute to this persistent inflammation. The aim of this study was to profile and evaluate the clinical significance of circulating nucleosomes in patients with Stage 5 chronic kidney disease (CKD5) on hemodialysis (HD). METHODS: Under institutional review board approval, plasma samples ...
Source: International Angiology - April 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Minimization of skin incisions at stripping by Mayo of large-diameter veins.
CONCLUSIONS: The use of the proposed stripper with an oval-ring head in patients with large-diameter subcutaneous trunks leads to the minimization of the skin incisions up to the punctures and, in general, makes the surgery significantly less traumatic, providing a quick recovery and minimization of the skin scars. PMID: 29557158 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - March 25, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Evaluation of three different devices to reduce stasis edema in poorly mobile nursing home patients.
CONCLUSIONS: This pilot study is to be added to the results of previous published studies showing the efficacy in reducting leg edema of Velcro® adjustable compression wrap and its ease of use. PMID: 29521485 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - March 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Relationship between the maximum carotid plaque area and the severity of coronary atherosclerosis.
Authors: He J, Chen P, Luo Y, Chen L, Li S, Pan Y, Fu S Abstract BACKGROUND: Carotid artery plaque is associated with coronary artery disease (CAD). Besides the presence of plaque, plaque characteristics is also related to the severity of CAD. So the characteristic difference of carotid plaque may affect this assessment role. However, it is unclear whether the maximum carotid plaque area can reflect the extents and severity of CAD. METHODS: We enrolled 388 consecutive CAD patients and 45 controls, and 204 patients were studied after excluding 184 patients without carotid plaque or coronary angiogram. Carotid in...
Source: International Angiology - March 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Lipid derivatives of arachidonic acid used as markers of atherosclerotic plaque instability: a pilot study.
Authors: Falkowski A, Gorący I, Kaczmarczyk M, Szemitko M, Bogacki H, Kostka J Abstract BACKGROUND: To compare the results of computer estimation of atherosclerotic plaque with biochemical data and ascertain any relationship with the occurrence of stroke. METHODS: The study involved 20 atherosclerotic plaques causing 70-99% stenosis of internal carotid arteries (ICA). Ultrasonographic examination (USG) images of plaques were analyzed using a computer program. A histogram was obtained for each plaque and a gray scale median (GSM) was determined for each histogram in order to measure the echogenicity of an exami...
Source: International Angiology - March 8, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Prevention of venous thromboembolism through the implementation of a risk assessment tool: a comparative study in medical and surgical patients.
Authors: Park MY, Fletcher JP, Hoffmann C, Lance A, Gavegan F, Hitos K Abstract BACKGROUND: Hospitalised patients are at high risk of venous thromboembolism (VTE). Underutilisation of thromboprophylaxis remains common despite existing clinical guidelines. The aim is to evaluate the implementation of a state wide standardised adult VTE risk assessment tool (RAT) to assist in the screening of inpatients and prescribing of appropriate thromboprophylaxis. METHODS: In total, 234 patients were audited using clinical notes and spot assessments for VTE risk at Western Sydney Local Health District over a two year period...
Source: International Angiology - February 23, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Predictors of early failure and secondary patency in native arteriovenous fistulas for hemodialysis.
CONCLUSIONS: Predictors of early and late events are slightly different. Elderly age and vein diameter had greater impact on early AVF failure. However, distal arterial hemodynamics showed prognostic value in native AVF secondary patency rate. PMID: 29424185 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 10, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Spinal cord injury in endovascular thoracoabdominal aortic aneurysm repair: prevalence, risk factors and preventive strategies.
Authors: Miranda V, Sousa J, Mansilha A Abstract Thoracoabdominal aortic aneurysms are among the most challenging pathologic conditions vascular surgeons have to face. Endovascular treatment brought the prospect of being able to treat these complex aneurysms with less invasiveness and recent outcomes already challenge those of open repair. Plus, this technique offers a therapeutic option for patients who had none, due to significant comorbidities limiting open repair. Spinal cord injury is a major complication after complex aneurysm repair that dramatically affects patient's quality of life, even if technical succe...
Source: International Angiology - February 10, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Vascular malformations: classification, diagnosis and treatment.
CONCLUSIONS: Vascular malformations are a complex group of pathologies, with different clinical presentations and treatment options, and therefore management by a multi-disciplinary team is essential. Their cure is often challenging and when not possible, treatment should aim at symptomatic control and improvement of patient's quality of life. PMID: 29424187 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 10, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Recurrent varices after surgery (REVAS): a clinical and color Doppler ultrasound scan analysis.
CONCLUSIONS: REVAS remain a major and still unsolved problem in patients following varicose veins surgery. Their clinical pictures and symptoms are heterogeneous and require a watchful analysis in order to identify both etiology and natural history. PMID: 29385790 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 3, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

The influence of patients' nutritional status on the prevalence, course and treatment outcomes of lower limb ischemia: an overview of current evidence.
CONCLUSIONS: There is a growing body of evidence concerning an association between LLI and patients' nutritional status. A so-called "obesity paradox" or "BMI paradox" seems to exist among patients with LLI and mainly concerns outcomes of endovascular and surgical treatment. However, further studies are needed to evaluate the clinical importance of body composition, the distribution and endocrine activity of adipose tissue, and the effect of weight reduction and/or nutritional support in the LLI patient group. PMID: 29385791 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 3, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Efficacy of micronized purified flavonoid fraction (Daflon ®) on improving individual symptoms, signs and quality of life in patients with chronic venous disease: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials.
Efficacy of micronized purified flavonoid fraction (Daflon®) on improving individual symptoms, signs and quality of life in patients with chronic venous disease: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials. Int Angiol. 2018 Jan 31;: Authors: Kakkos S, Nicolaides A Abstract INTRODUCTION: The use of a venoactive drug is considered an important component of medical treatment of chronic venous disease (CVD), although the efficacy of certain VADs on one or more individual leg symptoms or signs may have not been extensively studied to justify a strong recomm...
Source: International Angiology - February 3, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Investigation of non-saphenous veins in C0S patients.
CONCLUSIONS: CW Doppler, using a flat high-sensitivity probe, revealed the presence of a bidirectional flow that was significantly (P=.05) higher in C0S than in control patients, suggesting the presence of reflux in axial veins. These data give a new perspective on the management of C0S patients. PMID: 29376624 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - January 31, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Surgical revision vs. stent-graft to treat venous anastomosis stenosis following surgical thrombectomy of hemodialysis grafts.
CONCLUSIONS: Stent-graft implantation into stenotic VA of an occluded AVG showed to be effective and maintained good long-term patency. It is the preferred method due to its minimal invasiveness. The superiority of this method must be confirmed on a larger set of patients. PMID: 29376625 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - January 31, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

The influence of exercise on ulcer healing in patients with chronic venous insufficiency.
Authors: Mutlak O, Aslam M, Standfield N Abstract BACKGROUND: Venous Leg Ulcer (VLU) affects millions of people, and yet there have been no major advances in its treatment for many decades. Is it the time to change our approach, and try a multidisciplinary one that could bring about a change. The aim of this study is to evaluate whether a regular, home-based exercise could be influential in healing the VLU. METHODS: 80 subjects (mean age: 65.13 years) were recruited for 12 weeks. The participants were randomised into a control group (n=20), a compression therapy group (n=20), an exercise group (n=20) and a comp...
Source: International Angiology - January 27, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Peripheral arterial occlusive disease and perioperative risk.
Authors: Poredos P, Poredos P Abstract Surgical procedures represent a risk for different complications which may appear during the perioperative period. Cardiac ischemic events and vascular complications are the most important causes of increased morbidity and mortality and they are much more frequent in patients with manifest cardiovascular disease. This is particularly seen in patients with peripheral arterial occlusive disease (PAD), which represents advanced atherosclerosis frequently accompanied by the presence of coronary artery disease. Therefore, patients with PAD need careful preoperative examination, inc...
Source: International Angiology - January 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Endovascular thoracic aortic transection repair has equivalent survival to open repair after blunt thoracic aortic injury.
CONCLUSIONS: Although BTAI still carries a high mortality rate, data from our trauma center suggest that ER has equivalent survival when compared to OR. PMID: 29249118 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - December 19, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Chronic venous disease treated with sulodexide: a survey among primary care physicians in Mexico.
Authors: Flota Cervera LF, Frati Munari AC, Velázquez Herrera ÁE, Carbajal Contreras A Abstract BACKGROUND: Sulodexide is a glycosaminoglycan approved for the treatment of chronic venous disease (CVD). It has been available in Mexico since 2012. The aim of the study was to understand the clinical experience of primary care physicians in the treatment of CVD with sulodexide. METHODS: Clinical data collection forms were distributed among general practitioners. Data was collected for up to four follow-up consultations. All signs and symptoms were rated with the Likert Scale at each examination: 0 to ...
Source: International Angiology - November 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Drug-coated balloons reduce the risk of recurrent restenosis in arteriovenous fistulas and prosthetic grafts for hemodialysis.
Authors: Troisi N, Frosini P, Somma C, Romano E, Guidotti A, Dattolo PC, Ferro G, Chisci E, Michelagnoli S Abstract BACKGROUND: Aim of this study was to evaluate the early and mid-term outcomes of drug-coated balloons (DCBs) in hemodialysis patients with recurrent stenosis of arteriovenous fistula and previously treated with plain balloon angioplasty (PBA). METHODS: Between July 2013 and June 2016 38 hemodialysis patients with recurrent stenosis of arteriovenous fistula underwent endovascular treatment with a DCB at our center. All patients were previously treated at the target lesion with a PBA. The intervals ...
Source: International Angiology - November 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Estimating the hemodynamic influence of variable main body-to-iliac limb length ratios in aortic endografts.
CONCLUSIONS: Different L1/L2 rations are shown to have an impact on the pressure distribution along the entire EG while the length ratio predisposing to highest helicity or WSS values is also determined by the iliac limbs pattern of the EG. Since current custom-made EG solutions can reproduce variability in main-body / iliac limbs length ratios, further computational as well as clinical research is warranted to delineate and predict the hemodynamic and clinical effect of variable length ratios. PMID: 29072047 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - October 28, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

New data on chronic venous disease: a new place for Cyclo 3 ® Fort.
New data on chronic venous disease: a new place for Cyclo 3® Fort. Int Angiol. 2017 Oct 23;: Authors: Kakkos SK, Bouskela E, Jawien A, Nicolaides AN Abstract With our increasing knowledge of the epidemiology, pathophysiology, investigation and clinical aspects of chronic venous disease (CVD) and new data on the various therapies available, an update of the recommendations on CVD and its management appears to be necessary. The symposium "New Data on Chronic Venous Disease, New Place for Cyclo 3® Fort", held at the annual meeting of the European Venous Forum (EVF) on June 30th, 2017 in ...
Source: International Angiology - October 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Phosphoprotein 1 (osteopontin) gene (rs4754) affects markers of subclinical atherosclerosis in patients with type 2 diabetes mellitus.
CONCLUSIONS: We demonstrated an important effect of the SPP1 rs4754 on subclinical markers of carotid atherosclerosis in subjects with T2DM, however, as demonstrated by the multiple linear regression analysis, neither rs4754 nor rs28357094 had an important impact on the progression of subclinical markers of carotid atherosclerosis in subjects with T2DM. PMID: 28990744 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - October 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Diagnostic value of circulating microRNA-27a/b in patients with acute pulmonary embolism.
Authors: Wang Q, Ma J, Jiang Z, Wu F, Ping J, Ming L Abstract BACKGROUND: Circulating microRNAs (miRNAs) have been increasingly suggested as biomarkers for numerous diseases. The aims of this study were to evaluate the expression of plasma miR-27a/b in patients with acute pulmonary embolism (APE) and determine the possibility of miR-27a/b as diagnostic biomarkers for APE. METHODS: 78 APE patients diagnosed by computed tomographic pulmonary angiography (CTPA) and 70 age and gender matched normal volunteers were included in this study. The levels of miR-27a and miR-27b were measured by quantitative reverse transc...
Source: International Angiology - October 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Carbon-coated self-expandable stents in patients with atherosclerotic iliac artery disease.
CONCLUSIONS: Use of carbon-coated self-expandable stents in atherosclerotic iliac lesions was safe and effective. At 2 years, the patency rates and the absence of TLR were encouraging. Post-stent balloon dilatation should be recommended in all cases. Older patients and common iliac artery lesions were risk factors for restenosis in the mid-term period. PMID: 28994569 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - October 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Use of venoactive drugs after surgery for varicose veins: a preliminary study.
Authors: Mazzaccaro D, Muzzarelli L, Modafferi A, Righini PC, Settembrini AM, Nano G Abstract BACKGROUND: To assess the use of VenoActive Drugs (VADs) after surgery for chronic venous disease in our Operative Unit in terms of patients' compliance to the therapy and a possible effect on the postoperative pain and QoL. METHODS: Data of consecutive patients who underwent surgery were retrospectively analyzed. All patients, through telephone interview 90 days after the operation, were asked about taking the VAD (either sulodexide or MPFF) which was recommended during the postoperative period. Data were collected ab...
Source: International Angiology - October 6, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Tissue dielectric constant and circumference measurement in the follow-up of treatment related changes in lower limb lymphedema.
Authors: Tugral A, Viren T, Bakar Y Abstract BACKGROUND: Lymphedema of lower limbs is a chronic condition that requires life-long management. Therapeutic effect of Complex Decongestive Physiotherapy (CDP) is most often followed by circumference measurements (CM). However, the CM measurements are not specific to interstitial tissue fluid and have problems in sensitivity and objectivity. The aim of present study was to evaluate the therapeutic effect of CDP with a new tissue water specific measurement technique, in patients with lower limb lymphedema (LLL). MATERIAL AND METHODS: A total of 17 patients with unilat...
Source: International Angiology - September 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Benefits of micronized purified flavonoid fraction as adjuvant therapy on the inflammatory response after sclerotherapy.
CONCLUSIONS: Prescription of MPFF starting prior to sclerotherapy and throughout the post- operative period reduced the vein-specific pro-inflammatory reaction and may thereby reduce the unwanted side effects of sclerotherapy and improved treatment outcomes. PMID: 28945060 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research