Internal iliac artery preservation strategies in the endovascular treatment of aortoiliac aneurysms.
CONCLUSIONS: When determining the appropriate hypogastric preservation strategy, several factors should be considered. Anatomic criteria, life-expectancy as well as physical and sexual activity are the most important criteria. Procedure complexity and cost should also be accounted for. PMID: 30001612 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - July 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Midterm results with drug coated balloons for SFA lesions in patients with CLI: comparison with conventional bypass surgery.
CONCLUSIONS: Drug coated balloon angioplasty yields comparable results to surgery in the setting of critical ischemia. The efficacy and the safety of DCB's in more complex lesions is to be investigated with randomized trials. PMID: 29963797 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - July 4, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Improvement of arterial wall phenotype in subjects at moderate cardiovascular risk induced by very low-dose fluvastatin/valsartan combination: a pilot study.
CONCLUSIONS: This pilot study revealed that intervention with low-flu/val importantly shifts the arterial wall phenotype in a lower risk direction. This improvement could be interpolated into clinical benefits that remain to be further studied. PMID: 29952159 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - June 30, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Heparin promotes recanalization of venous thrombotic occlusions.
Authors: Poredos P, Poredos P, Jezovnik MK Abstract Thrombosis is a consequence of disbalance between the procoagulant and fibrinolytic activity of blood and is frequently associated with chronic sequelae, which are the consequence of chronic occlusion of affected veins. Treatment of venous thrombosis should not be oriented in the prevention of thrombus progression and associated thromboembolic events, but also in stimulation of thrombolysis and recanalization of occluded veins, which are one of the most important preventive mechanisms of late sequelae, including post-thrombotic syndrome. The treatment of acute ven...
Source: International Angiology - June 28, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Epidemiology of peripheral artery disease in Europe: VAS Educational Paper.
Authors: Olinic DM, Spinu M, Olinic M, Homorodean C, Tataru DA, Liew A, Schernthaner GH, Stanek A, Fowkes G, Catalano M Abstract This paper reviews the current epidemiological data on peripheral artery disease (PAD) in Europe. Cardiovascular disease (CVD) burden is presented and PAD prevalence is discussed, as compared to coronary (CAD) and cerebrovascular (CeVD) diseases, in European Union (EU) countries and European continent countries. The article reviews PAD clinical manifestations, PAD diagnosis, risk factors for PAD incidence and progression, PAD prognosis and financial implications. CVD mortality is higher i...
Source: International Angiology - June 28, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Management of chronic venous disorders of the lower limbs. Guidelines According to Scientific Evidence. Part I.
Authors: Nicolaides A, Kakkos S, Baekgaard N, Comerota A, de Maesenner M, Eklof B, Giannoukas AD, Lugli M, Maleti O, Myers K, Nelzén O, Partsch H, Perrin M PMID: 29871479 [PubMed - in process] (Source: International Angiology)
Source: International Angiology - June 7, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Predictive factors of a poor outcome following revascularization for critical limb ischemia: implications for practice.
CONCLUSIONS: Certain preoperative variables can predict satisfactorily the short-term outcome after revascularization for CLI, although they are not sufficiently useful to identify the patient in whom revascularization can be clearly futile. Further research is needed to refine a predictive model suitable for decision-making. PMID: 29792018 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - May 25, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Predictors of long-term mortality following elective endovascular repair of abdominal aortic aneurysms.
CONCLUSIONS: Risk factors associated with long-term mortality following elective EVAR remain scarcely published. Several demographic, anatomical, cardiovascular, pulmonary and renal co-morbidities seem to have an association with long-term mortality. Critical scrutiny of clinical patient status remains fundamental for a fair health resources allocation. PMID: 29745617 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - May 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Medical management of stable peripheral artery disease (PAD) and the COMPASS trial. Are we improving medical care? Perspectives from a vascular standpoint.
Authors: Ramacciotti E, Castelli V, Walenga J, Fareed J PMID: 29745618 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - May 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

31P MR spectroscopy of patients with mild and serious lower limb ischemia.
CONCLUSIONS: A combination of rest and dynamic 31P MR spectroscopy can distinguish all three groups of subjects. On the other hand, examination at rest is sufficient for differentiation between patiens' groups and verification of severe ischemia. PMID: 29644834 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - April 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Risk assessment as a guide for the prevention of cancer-associated thromboembolism.
Authors: Al-Ogaili A, Fuentes HE, Tafur AJ, Caprini J Abstract Venous thromboembolism (VTE) is a major source of morbidity and mortality among patients diagnosed with cancer. In addition to an increased risk of VTE, patients with cancer are at higher risk of bleeding while receiving therapeutic anticoagulation. Aggressive and targeted thromboprophylaxis is a crucial practice to avoid the dreaded complications of VTE. Risk assessment models (RAM) are tools developed to identify high-risk patients in whom thromboprophylaxis is beneficial. This review describes the most validated VTE RAMs in patients with cancer. ...
Source: International Angiology - April 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Elevated extracellular nucleosomes and their relevance to inflammation in stage 5 chronic kidney disease.
Authors: Phan T, McMillan R, Skiadopoulos L, Walborn A, Hoppensteadt D, Fareed J, Bansal V Abstract BACKGROUND: Chronic kidney disease is a disorder characterized by a pro-inflammatory state that is associated with increased morbidity and mortality. Endogenous damage- associated molecular patterns, including nucleosomes, may contribute to this persistent inflammation. The aim of this study was to profile and evaluate the clinical significance of circulating nucleosomes in patients with Stage 5 chronic kidney disease (CKD5) on hemodialysis (HD). METHODS: Under institutional review board approval, plasma samples ...
Source: International Angiology - April 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Minimization of skin incisions at stripping by Mayo of large-diameter veins.
CONCLUSIONS: The use of the proposed stripper with an oval-ring head in patients with large-diameter subcutaneous trunks leads to the minimization of the skin incisions up to the punctures and, in general, makes the surgery significantly less traumatic, providing a quick recovery and minimization of the skin scars. PMID: 29557158 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - March 25, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Evaluation of three different devices to reduce stasis edema in poorly mobile nursing home patients.
CONCLUSIONS: This pilot study is to be added to the results of previous published studies showing the efficacy in reducting leg edema of Velcro® adjustable compression wrap and its ease of use. PMID: 29521485 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - March 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Relationship between the maximum carotid plaque area and the severity of coronary atherosclerosis.
Authors: He J, Chen P, Luo Y, Chen L, Li S, Pan Y, Fu S Abstract BACKGROUND: Carotid artery plaque is associated with coronary artery disease (CAD). Besides the presence of plaque, plaque characteristics is also related to the severity of CAD. So the characteristic difference of carotid plaque may affect this assessment role. However, it is unclear whether the maximum carotid plaque area can reflect the extents and severity of CAD. METHODS: We enrolled 388 consecutive CAD patients and 45 controls, and 204 patients were studied after excluding 184 patients without carotid plaque or coronary angiogram. Carotid in...
Source: International Angiology - March 11, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Lipid derivatives of arachidonic acid used as markers of atherosclerotic plaque instability: a pilot study.
Authors: Falkowski A, Gorący I, Kaczmarczyk M, Szemitko M, Bogacki H, Kostka J Abstract BACKGROUND: To compare the results of computer estimation of atherosclerotic plaque with biochemical data and ascertain any relationship with the occurrence of stroke. METHODS: The study involved 20 atherosclerotic plaques causing 70-99% stenosis of internal carotid arteries (ICA). Ultrasonographic examination (USG) images of plaques were analyzed using a computer program. A histogram was obtained for each plaque and a gray scale median (GSM) was determined for each histogram in order to measure the echogenicity of an exami...
Source: International Angiology - March 8, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Prevention of venous thromboembolism through the implementation of a risk assessment tool: a comparative study in medical and surgical patients.
Authors: Park MY, Fletcher JP, Hoffmann C, Lance A, Gavegan F, Hitos K Abstract BACKGROUND: Hospitalised patients are at high risk of venous thromboembolism (VTE). Underutilisation of thromboprophylaxis remains common despite existing clinical guidelines. The aim is to evaluate the implementation of a state wide standardised adult VTE risk assessment tool (RAT) to assist in the screening of inpatients and prescribing of appropriate thromboprophylaxis. METHODS: In total, 234 patients were audited using clinical notes and spot assessments for VTE risk at Western Sydney Local Health District over a two year period...
Source: International Angiology - February 23, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Predictors of early failure and secondary patency in native arteriovenous fistulas for hemodialysis.
CONCLUSIONS: Predictors of early and late events are slightly different. Elderly age and vein diameter had greater impact on early AVF failure. However, distal arterial hemodynamics showed prognostic value in native AVF secondary patency rate. PMID: 29424185 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 10, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Spinal cord injury in endovascular thoracoabdominal aortic aneurysm repair: prevalence, risk factors and preventive strategies.
Authors: Miranda V, Sousa J, Mansilha A Abstract Thoracoabdominal aortic aneurysms are among the most challenging pathologic conditions vascular surgeons have to face. Endovascular treatment brought the prospect of being able to treat these complex aneurysms with less invasiveness and recent outcomes already challenge those of open repair. Plus, this technique offers a therapeutic option for patients who had none, due to significant comorbidities limiting open repair. Spinal cord injury is a major complication after complex aneurysm repair that dramatically affects patient's quality of life, even if technical succe...
Source: International Angiology - February 10, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Vascular malformations: classification, diagnosis and treatment.
CONCLUSIONS: Vascular malformations are a complex group of pathologies, with different clinical presentations and treatment options, and therefore management by a multi-disciplinary team is essential. Their cure is often challenging and when not possible, treatment should aim at symptomatic control and improvement of patient's quality of life. PMID: 29424187 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 10, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Recurrent varices after surgery (REVAS): a clinical and color Doppler ultrasound scan analysis.
CONCLUSIONS: REVAS remain a major and still unsolved problem in patients following varicose veins surgery. Their clinical pictures and symptoms are heterogeneous and require a watchful analysis in order to identify both etiology and natural history. PMID: 29385790 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 3, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

The influence of patients' nutritional status on the prevalence, course and treatment outcomes of lower limb ischemia: an overview of current evidence.
CONCLUSIONS: There is a growing body of evidence concerning an association between LLI and patients' nutritional status. A so-called "obesity paradox" or "BMI paradox" seems to exist among patients with LLI and mainly concerns outcomes of endovascular and surgical treatment. However, further studies are needed to evaluate the clinical importance of body composition, the distribution and endocrine activity of adipose tissue, and the effect of weight reduction and/or nutritional support in the LLI patient group. PMID: 29385791 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - February 3, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Efficacy of micronized purified flavonoid fraction (Daflon ®) on improving individual symptoms, signs and quality of life in patients with chronic venous disease: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials.
Efficacy of micronized purified flavonoid fraction (Daflon®) on improving individual symptoms, signs and quality of life in patients with chronic venous disease: a systematic review and meta-analysis of randomized double-blind placebo-controlled trials. Int Angiol. 2018 Jan 31;: Authors: Kakkos S, Nicolaides A Abstract INTRODUCTION: The use of a venoactive drug is considered an important component of medical treatment of chronic venous disease (CVD), although the efficacy of certain VADs on one or more individual leg symptoms or signs may have not been extensively studied to justify a strong recomm...
Source: International Angiology - February 3, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Investigation of non-saphenous veins in C0S patients.
CONCLUSIONS: CW Doppler, using a flat high-sensitivity probe, revealed the presence of a bidirectional flow that was significantly (P=.05) higher in C0S than in control patients, suggesting the presence of reflux in axial veins. These data give a new perspective on the management of C0S patients. PMID: 29376624 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - January 31, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Surgical revision vs. stent-graft to treat venous anastomosis stenosis following surgical thrombectomy of hemodialysis grafts.
CONCLUSIONS: Stent-graft implantation into stenotic VA of an occluded AVG showed to be effective and maintained good long-term patency. It is the preferred method due to its minimal invasiveness. The superiority of this method must be confirmed on a larger set of patients. PMID: 29376625 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - January 31, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

The influence of exercise on ulcer healing in patients with chronic venous insufficiency.
Authors: Mutlak O, Aslam M, Standfield N Abstract BACKGROUND: Venous Leg Ulcer (VLU) affects millions of people, and yet there have been no major advances in its treatment for many decades. Is it the time to change our approach, and try a multidisciplinary one that could bring about a change. The aim of this study is to evaluate whether a regular, home-based exercise could be influential in healing the VLU. METHODS: 80 subjects (mean age: 65.13 years) were recruited for 12 weeks. The participants were randomised into a control group (n=20), a compression therapy group (n=20), an exercise group (n=20) and a comp...
Source: International Angiology - January 27, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Peripheral arterial occlusive disease and perioperative risk.
Authors: Poredos P, Poredos P Abstract Surgical procedures represent a risk for different complications which may appear during the perioperative period. Cardiac ischemic events and vascular complications are the most important causes of increased morbidity and mortality and they are much more frequent in patients with manifest cardiovascular disease. This is particularly seen in patients with peripheral arterial occlusive disease (PAD), which represents advanced atherosclerosis frequently accompanied by the presence of coronary artery disease. Therefore, patients with PAD need careful preoperative examination, inc...
Source: International Angiology - January 14, 2018 Category: Cardiology Tags: Int Angiol Source Type: research

Endovascular thoracic aortic transection repair has equivalent survival to open repair after blunt thoracic aortic injury.
CONCLUSIONS: Although BTAI still carries a high mortality rate, data from our trauma center suggest that ER has equivalent survival when compared to OR. PMID: 29249118 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - December 19, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Chronic venous disease treated with sulodexide: a survey among primary care physicians in Mexico.
Authors: Flota Cervera LF, Frati Munari AC, Velázquez Herrera ÁE, Carbajal Contreras A Abstract BACKGROUND: Sulodexide is a glycosaminoglycan approved for the treatment of chronic venous disease (CVD). It has been available in Mexico since 2012. The aim of the study was to understand the clinical experience of primary care physicians in the treatment of CVD with sulodexide. METHODS: Clinical data collection forms were distributed among general practitioners. Data was collected for up to four follow-up consultations. All signs and symptoms were rated with the Likert Scale at each examination: 0 to ...
Source: International Angiology - November 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Drug-coated balloons reduce the risk of recurrent restenosis in arteriovenous fistulas and prosthetic grafts for hemodialysis.
Authors: Troisi N, Frosini P, Somma C, Romano E, Guidotti A, Dattolo PC, Ferro G, Chisci E, Michelagnoli S Abstract BACKGROUND: Aim of this study was to evaluate the early and mid-term outcomes of drug-coated balloons (DCBs) in hemodialysis patients with recurrent stenosis of arteriovenous fistula and previously treated with plain balloon angioplasty (PBA). METHODS: Between July 2013 and June 2016 38 hemodialysis patients with recurrent stenosis of arteriovenous fistula underwent endovascular treatment with a DCB at our center. All patients were previously treated at the target lesion with a PBA. The intervals ...
Source: International Angiology - November 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Estimating the hemodynamic influence of variable main body-to-iliac limb length ratios in aortic endografts.
CONCLUSIONS: Different L1/L2 rations are shown to have an impact on the pressure distribution along the entire EG while the length ratio predisposing to highest helicity or WSS values is also determined by the iliac limbs pattern of the EG. Since current custom-made EG solutions can reproduce variability in main-body / iliac limbs length ratios, further computational as well as clinical research is warranted to delineate and predict the hemodynamic and clinical effect of variable length ratios. PMID: 29072047 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - October 28, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

New data on chronic venous disease: a new place for Cyclo 3 ® Fort.
New data on chronic venous disease: a new place for Cyclo 3® Fort. Int Angiol. 2017 Oct 23;: Authors: Kakkos SK, Bouskela E, Jawien A, Nicolaides AN Abstract With our increasing knowledge of the epidemiology, pathophysiology, investigation and clinical aspects of chronic venous disease (CVD) and new data on the various therapies available, an update of the recommendations on CVD and its management appears to be necessary. The symposium "New Data on Chronic Venous Disease, New Place for Cyclo 3® Fort", held at the annual meeting of the European Venous Forum (EVF) on June 30th, 2017 in ...
Source: International Angiology - October 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Phosphoprotein 1 (osteopontin) gene (rs4754) affects markers of subclinical atherosclerosis in patients with type 2 diabetes mellitus.
CONCLUSIONS: We demonstrated an important effect of the SPP1 rs4754 on subclinical markers of carotid atherosclerosis in subjects with T2DM, however, as demonstrated by the multiple linear regression analysis, neither rs4754 nor rs28357094 had an important impact on the progression of subclinical markers of carotid atherosclerosis in subjects with T2DM. PMID: 28990744 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - October 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Diagnostic value of circulating microRNA-27a/b in patients with acute pulmonary embolism.
Authors: Wang Q, Ma J, Jiang Z, Wu F, Ping J, Ming L Abstract BACKGROUND: Circulating microRNAs (miRNAs) have been increasingly suggested as biomarkers for numerous diseases. The aims of this study were to evaluate the expression of plasma miR-27a/b in patients with acute pulmonary embolism (APE) and determine the possibility of miR-27a/b as diagnostic biomarkers for APE. METHODS: 78 APE patients diagnosed by computed tomographic pulmonary angiography (CTPA) and 70 age and gender matched normal volunteers were included in this study. The levels of miR-27a and miR-27b were measured by quantitative reverse transc...
Source: International Angiology - October 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Carbon-coated self-expandable stents in patients with atherosclerotic iliac artery disease.
CONCLUSIONS: Use of carbon-coated self-expandable stents in atherosclerotic iliac lesions was safe and effective. At 2 years, the patency rates and the absence of TLR were encouraging. Post-stent balloon dilatation should be recommended in all cases. Older patients and common iliac artery lesions were risk factors for restenosis in the mid-term period. PMID: 28994569 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - October 12, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Use of venoactive drugs after surgery for varicose veins: a preliminary study.
Authors: Mazzaccaro D, Muzzarelli L, Modafferi A, Righini PC, Settembrini AM, Nano G Abstract BACKGROUND: To assess the use of VenoActive Drugs (VADs) after surgery for chronic venous disease in our Operative Unit in terms of patients' compliance to the therapy and a possible effect on the postoperative pain and QoL. METHODS: Data of consecutive patients who underwent surgery were retrospectively analyzed. All patients, through telephone interview 90 days after the operation, were asked about taking the VAD (either sulodexide or MPFF) which was recommended during the postoperative period. Data were collected ab...
Source: International Angiology - October 6, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Tissue dielectric constant and circumference measurement in the follow-up of treatment related changes in lower limb lymphedema.
Authors: Tugral A, Viren T, Bakar Y Abstract BACKGROUND: Lymphedema of lower limbs is a chronic condition that requires life-long management. Therapeutic effect of Complex Decongestive Physiotherapy (CDP) is most often followed by circumference measurements (CM). However, the CM measurements are not specific to interstitial tissue fluid and have problems in sensitivity and objectivity. The aim of present study was to evaluate the therapeutic effect of CDP with a new tissue water specific measurement technique, in patients with lower limb lymphedema (LLL). MATERIAL AND METHODS: A total of 17 patients with unilat...
Source: International Angiology - September 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Benefits of micronized purified flavonoid fraction as adjuvant therapy on the inflammatory response after sclerotherapy.
CONCLUSIONS: Prescription of MPFF starting prior to sclerotherapy and throughout the post- operative period reduced the vein-specific pro-inflammatory reaction and may thereby reduce the unwanted side effects of sclerotherapy and improved treatment outcomes. PMID: 28945060 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

A comparative study of CFD of canine model of common carotid fusiform aneurysm and vertebrobasilar fusiform aneurysm in human patients.
CONCLUSIONS: The canine fusiform aneurysm model exhibits high similarity in morphology and hemodynamics with human patients'. Therefore, this model can be used to study the fluid-solid interaction in the aneurysm and to explore the underlying mechanisms of the development, rupture and occurrence of IFAs, which offers a pathophysiological tool to seek better treatments of IFAs. PMID: 28945061 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Early recanalization of veins in patients with DVT treated with rivaroxaban: do we need to move from bedside to bench again?
Authors: Ramacciotti E, Giova Volpiani G, Dávila R, Resende Aguiar VC, Fareed J Abstract Rivaroxaban is one of the direct non-vitamin K antagonists (DOACs) that is globally approved for single drug approach to treat venous thromboembolism (VTE). Its usage is growing quickly, given the practicality of single daily dose, no need for monitoring and a better safety profile compared with that of vitamin K antagonists (VKA). As real world experience with rivaroxaban accumulates, isolated reports regarding its ability to promote earlier and more intense venous recanalization compared with VKA treatment have been pu...
Source: International Angiology - September 26, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Factors affecting the validity of the oscillometric ankle brachial index to detect peripheral arterial disease.
This study aimed to evaluate those factors affecting the validity of oscillometric ABI in comparison to Doppler ABI to detect PAD. METHODS: Through univariate and multivariate linear regression, we studied those factors affecting the differences between oscillometric and Doppler ABI; through univariate and multivariate logistic regression we analyzed the false negative rate of oscillometric ABI to detect PAD. RESULTS: We analyzed 197 consecutive subjects (394 legs) from two settings: Primary Care and Vascular Service. The means of oscillometric ABI and Doppler ABI were 1.094 (95%CI: 0.843-1.345) and 1.073 (95%CI: 0.769-1.374) (p
Source: International Angiology - September 13, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Is management of complex abdominal aortic aneurysms consistent across the UK? A questionnaire-based survey.
CONCLUSIONS: The study results support anecdotal variation in practice among vascular specialists. This reflects the lack of solid evidence on the optimal management of complex AAA. PMID: 28895367 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 13, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Gestational lower limb edema and venous reflux in healthy primigravidae.
CONCLUSIONS: In healthy primigravidae, lower limb edema was not associated with venous reflux. Both were present in the second and in the third trimesters of pregnancy and resolved spontaneously in the postpartum period. Both are products of the same physiological changes that occur in pregnancy. PMID: 28895368 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 13, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

The role of intravascular ultrasound in lower limb revascularization in patients with peripheral arterial disease.
CONCLUSIONS: There is limited and heterogeneous evidence regarding the use of IVUS for the management of PAD. Further research is required to elucidate the optimal role of IVUS in PAD as well as the cost effectiveness of this approach for routine use in the management of PAD. PMID: 28895369 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 13, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Staged endovascular repair of critical limb ischemia in high risk patients: the procedural and clinical outcomes.
CONCLUSIONS: Staged endovascular treatment in high-risk CLI patients can effectively relieve rest pain and symptoms of necrosis, which greatly improves the survival and quality of life of patients less suited for conventional repair. PMID: 28884985 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 9, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Nocturnal leg symptoms are not associated with specific patterns of superficial venous insufficiency.
CONCLUSIONS: No significant difference was detected between patterns of superficial venous reflux in patients with nocturnal symptoms compared to those without nocturnal symptoms. In addition, the presence of nocturnal symptoms does not predict a specific pattern of disease. Future studies are needed to determine whether correction of the main truncal disease is sufficient or if ablation of both the truncal and tributary veins is necessary for alleviation of nocturnal symptoms. PMID: 28854778 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 2, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Patients' opinions regarding research and management of abdominal aortic aneurysms.
CONCLUSIONS: The results represent a snapshot of patient's views in terms of priorities for AAA research. We further demonstrate how patient's opinions can signpost the potential path for biomarker research to impact clinical practice. PMID: 28854779 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 2, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

More on carotid atherosclerosis and ezetimibe.
Authors: Paraskevas KI, Mikhailidis DP PMID: 28854780 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - September 2, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Efficacy of ezetimibe combined with atorvastatin in treatment of carotid artery plaque in patients with type 2 diabetes mellitus complicated with coronary heart disease.
Authors: Wang J, Ai XB, Wang F, Zou YW, Li L, Yi XL Abstract BACKGROUND: To evaluate the efficacy of ezetimibe combined with atorvastatin in treatment of carotid artery plaque in patients with type 2 diabetes mellitus complicated with coronary heart disease (CHD). METHODS: A total of 100 patients with carotid atherosclerosis (CAS) confirmed by ultrasound and diagnosed with type 2 diabetes mellitus and CHD were randomly assigned to atorvastatin group (atorvastatin 20 mg/d) or combined treatment group (ezetimibe 10 mg/d and atorvastatin 20 mg/d). All those patients were followed for 12 months. Serum lipid, ALT, A...
Source: International Angiology - June 25, 2017 Category: Cardiology Tags: Int Angiol Source Type: research

Extended use of sulodexide, apixaban, rivaroxaban and dabigatran in venous thromboembolism. Indirect comparison of clinical trials.
Authors: Tomkowski W, Kuca P, Bignamini AA, Andreozzi GM PMID: 28641408 [PubMed - as supplied by publisher] (Source: International Angiology)
Source: International Angiology - June 25, 2017 Category: Cardiology Tags: Int Angiol Source Type: research