Effect and potential mechanism of nitrite reductase B on nitrite degradation by < em > Limosilactobacillus fermentum < /em > RC4
Curr Res Food Sci. 2024 Apr 24;8:100749. doi: 10.1016/j.crfs.2024.100749. eCollection 2024.ABSTRACTNitrite has the potential risk of hypoxic poisoning or cancer in pickled food. In our previous study, Limosilactobacillus fermentum (L. fermentum) RC4 is effective in nitrite degradation by producing nitrite reductase B (NirB). To investigate the detailed mechanism from the genome, response, and regulation of NirB, the whole-genome sequence of L. fermentum RC4 was analyzed, the L. fermentum-EGFP-nirB with enhanced green fluorescent protein (EGFP) labeled the nitrite reductase large subunit nirB, and the recombined L. fermentu...
Source: Cancer Control - May 2, 2024 Category: Cancer & Oncology Authors: Qing Fan Chaoran Xia Xiaoqun Zeng Zhen Wu Yuxing Guo Qiwei Du Maolin Tu Xinanbei Liu Daodong Pan Source Type: research
State COVID-19 Policies and Drug Overdose Mortality Among Working-Age Adults in the United States, 2020
Conclusions. The economic supports that states enacted were insufficient to fully mitigate the adverse relationship between activity limitations and drug overdoses. (Am J Public Health. Published online ahead of print May 2, 2024:e1-e9. https://doi.org/10.2105/AJPH.2024.307621).PMID:38696735 | DOI:10.2105/AJPH.2024.307621 (Source: American Journal of Public Health)
Source: American Journal of Public Health - May 2, 2024 Category: International Medicine & Public Health Authors: Douglas A Wolf Shannon M Monnat Emily E Wiemers Yue Sun Xue Zhang Elyse R Grossman Jennifer Karas Montez Source Type: research
State COVID-19 Policies and Drug Overdose Mortality Among Working-Age Adults in the United States, 2020
Conclusions. The economic supports that states enacted were insufficient to fully mitigate the adverse relationship between activity limitations and drug overdoses. (Am J Public Health. Published online ahead of print May 2, 2024:e1-e9. https://doi.org/10.2105/AJPH.2024.307621).PMID:38696735 | DOI:10.2105/AJPH.2024.307621 (Source: Am J Public Health)
Source: Am J Public Health - May 2, 2024 Category: International Medicine & Public Health Authors: Douglas A Wolf Shannon M Monnat Emily E Wiemers Yue Sun Xue Zhang Elyse R Grossman Jennifer Karas Montez Source Type: research
Recuperative Effects of Cinnamon (Cinnamomum zeylanicum) in Catla catla After Sub-Lethal Exposure to Lead
Biol Trace Elem Res. 2024 May 2. doi: 10.1007/s12011-024-04213-5. Online ahead of print.ABSTRACTThis research was conducted to validate the beneficial effects of incorporating dietary cinnamon (Cinnamomum zeylanicum) powder (CzP) in alleviating lead (Pb) poisoning in fish. Healthy Catla catla individuals (16.36 ± 0.19 g/fish) were distributed across 18 tanks in triplicate groups. The experimental groups were as follows: Control group: fish without supplementation or exposure to Pb; positive control group: fish without supplementation but exposed to 1 mg/L Pb; 5 g/kg CzP along with 1 mg/L Pb exposure; 10 g/kg CzP along wit...
Source: Biological Trace Element Research - May 2, 2024 Category: Biology Authors: Zeeshan Yousaf Syed Makhdoom Hussain Shafaqat Ali Pallab K Sarker Khalid A Al-Ghanim Source Type: research
Lead poisoning of raptors: state of the science and cross-discipline mitigation options for a global problem
Biol Rev Camb Philos Soc. 2024 May 2. doi: 10.1111/brv.13087. Online ahead of print.ABSTRACTLead poisoning is an important global conservation problem for many species of wildlife, especially raptors. Despite the increasing number of individual studies and regional reviews of lead poisoning of raptors, it has been over a decade since this information has been compiled into a comprehensive global review. Here, we summarize the state of knowledge of lead poisoning of raptors, we review developments in manufacturing of non-lead ammunition, the use of which can reduce the most pervasive source of lead these birds encounter, an...
Source: Biological Reviews of the Cambridge Philosophical Society - May 2, 2024 Category: Biology Authors: Todd E Katzner Deborah J Pain Michael McTee Leland Brown Sandra Cuadros Mark Pokras Vincent A Slabe Richard T Watson Guillermo Wiemeyer Bryan Bedrosian Jordan O Hampton Chris N Parish James M Pay Keisuke Saito John H Schulz Source Type: research
Identification of FTY720 and COH29 as novel topoisomerase I catalytic inhibitors by experimental and computational studies
Bioorg Chem. 2024 Apr 29;147:107412. doi: 10.1016/j.bioorg.2024.107412. Online ahead of print.ABSTRACTThe development of novel topoisomerase I (TOP1) inhibitors is crucial for overcoming the drawbacks and limitations of current TOP1 poisons. Here, we identified two potential TOP1 inhibitors, namely, FTY720 (a sphingosine 1-phosphate antagonist) and COH29 (a ribonucleotide reductase inhibitor), through experimental screening of known active compounds. Biological experiments verified that FTY720 and COH29 were nonintercalative TOP1 catalytic inhibitors that did not induce the formation of DNA-TOP1 covalent complexes. Molecul...
Source: Bioorganic Chemistry - May 2, 2024 Category: Chemistry Authors: Huang Zeng Shengyuan Zhang Hua Nie Junhao Li Jiunlong Yang Yuanbei Zhuang Yingjie Huang Miao Zeng Source Type: research
Clozapine Use Among People With Psychotic Disorders Who Experience Specific Indications for Clozapine
Conclusions: Initiating clozapine treatment is uncommon among people with psychotic disorders who experience events suggesting clozapine is indicated, with even lower rates among Black and Hispanic patients.PMID:38696137 | DOI:10.4088/JCP.23m14833 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - May 2, 2024 Category: Psychiatry Authors: Gregory E Simon Rebecca C Rossom Esti Iturralde Brian K Ahmedani Stephen C Waring Ashli A Owen-Smith Stacy A Sterling Kathleen Miley Cheryl D Stults Yihe G Daida Frances L Lynch Arne Beck Katherine Sanchez Karen J Coleman Susan M Shortreed Source Type: research
Increased Long-Term Risk of Dementia in Patients With Carbon Monoxide Poisoning: A Systematic Review and Meta-Analysis of Cohort Studies
CONCLUSION: Overall the evidence from prospective cohort studies supported a link between CO exposure and an increased dementia risk, although all the included studies were limited to Taiwanese population.PMID:38695039 | DOI:10.30773/pi.2021.0134 (Source: Psychiatry Investigation)
Source: Psychiatry Investigation - May 2, 2024 Category: Psychiatry Authors: Meixian Zhang Zhu Liduzi Jiesisibieke Ho-Shan Wei Pei-En Chen Ching-Wen Chien Ping Tao Tao-Hsin Tung Source Type: research
State COVID-19 Policies and Drug Overdose Mortality Among Working-Age Adults in the United States, 2020
Conclusions. The economic supports that states enacted were insufficient to fully mitigate the adverse relationship between activity limitations and drug overdoses. (Am J Public Health. Published online ahead of print May 2, 2024:e1-e9. https://doi.org/10.2105/AJPH.2024.307621).PMID:38696735 | DOI:10.2105/AJPH.2024.307621 (Source: American Journal of Public Health)
Source: American Journal of Public Health - May 2, 2024 Category: International Medicine & Public Health Authors: Douglas A Wolf Shannon M Monnat Emily E Wiemers Yue Sun Xue Zhang Elyse R Grossman Jennifer Karas Montez Source Type: research
State COVID-19 Policies and Drug Overdose Mortality Among Working-Age Adults in the United States, 2020
Conclusions. The economic supports that states enacted were insufficient to fully mitigate the adverse relationship between activity limitations and drug overdoses. (Am J Public Health. Published online ahead of print May 2, 2024:e1-e9. https://doi.org/10.2105/AJPH.2024.307621).PMID:38696735 | DOI:10.2105/AJPH.2024.307621 (Source: Am J Public Health)
Source: Am J Public Health - May 2, 2024 Category: International Medicine & Public Health Authors: Douglas A Wolf Shannon M Monnat Emily E Wiemers Yue Sun Xue Zhang Elyse R Grossman Jennifer Karas Montez Source Type: research
Recuperative Effects of Cinnamon (Cinnamomum zeylanicum) in Catla catla After Sub-Lethal Exposure to Lead
Biol Trace Elem Res. 2024 May 2. doi: 10.1007/s12011-024-04213-5. Online ahead of print.ABSTRACTThis research was conducted to validate the beneficial effects of incorporating dietary cinnamon (Cinnamomum zeylanicum) powder (CzP) in alleviating lead (Pb) poisoning in fish. Healthy Catla catla individuals (16.36 ± 0.19 g/fish) were distributed across 18 tanks in triplicate groups. The experimental groups were as follows: Control group: fish without supplementation or exposure to Pb; positive control group: fish without supplementation but exposed to 1 mg/L Pb; 5 g/kg CzP along with 1 mg/L Pb exposure; 10 g/kg CzP along wit...
Source: Biological Trace Element Research - May 2, 2024 Category: Biology Authors: Zeeshan Yousaf Syed Makhdoom Hussain Shafaqat Ali Pallab K Sarker Khalid A Al-Ghanim Source Type: research
Lead poisoning of raptors: state of the science and cross-discipline mitigation options for a global problem
Biol Rev Camb Philos Soc. 2024 May 2. doi: 10.1111/brv.13087. Online ahead of print.ABSTRACTLead poisoning is an important global conservation problem for many species of wildlife, especially raptors. Despite the increasing number of individual studies and regional reviews of lead poisoning of raptors, it has been over a decade since this information has been compiled into a comprehensive global review. Here, we summarize the state of knowledge of lead poisoning of raptors, we review developments in manufacturing of non-lead ammunition, the use of which can reduce the most pervasive source of lead these birds encounter, an...
Source: Biological Reviews of the Cambridge Philosophical Society - May 2, 2024 Category: Biology Authors: Todd E Katzner Deborah J Pain Michael McTee Leland Brown Sandra Cuadros Mark Pokras Vincent A Slabe Richard T Watson Guillermo Wiemeyer Bryan Bedrosian Jordan O Hampton Chris N Parish James M Pay Keisuke Saito John H Schulz Source Type: research
Identification of FTY720 and COH29 as novel topoisomerase I catalytic inhibitors by experimental and computational studies
Bioorg Chem. 2024 Apr 29;147:107412. doi: 10.1016/j.bioorg.2024.107412. Online ahead of print.ABSTRACTThe development of novel topoisomerase I (TOP1) inhibitors is crucial for overcoming the drawbacks and limitations of current TOP1 poisons. Here, we identified two potential TOP1 inhibitors, namely, FTY720 (a sphingosine 1-phosphate antagonist) and COH29 (a ribonucleotide reductase inhibitor), through experimental screening of known active compounds. Biological experiments verified that FTY720 and COH29 were nonintercalative TOP1 catalytic inhibitors that did not induce the formation of DNA-TOP1 covalent complexes. Molecul...
Source: Bioorganic Chemistry - May 2, 2024 Category: Chemistry Authors: Huang Zeng Shengyuan Zhang Hua Nie Junhao Li Jiunlong Yang Yuanbei Zhuang Yingjie Huang Miao Zeng Source Type: research
Clozapine Use Among People With Psychotic Disorders Who Experience Specific Indications for Clozapine
Conclusions: Initiating clozapine treatment is uncommon among people with psychotic disorders who experience events suggesting clozapine is indicated, with even lower rates among Black and Hispanic patients.PMID:38696137 | DOI:10.4088/JCP.23m14833 (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - May 2, 2024 Category: Psychiatry Authors: Gregory E Simon Rebecca C Rossom Esti Iturralde Brian K Ahmedani Stephen C Waring Ashli A Owen-Smith Stacy A Sterling Kathleen Miley Cheryl D Stults Yihe G Daida Frances L Lynch Arne Beck Katherine Sanchez Karen J Coleman Susan M Shortreed Source Type: research
Increased Long-Term Risk of Dementia in Patients With Carbon Monoxide Poisoning: A Systematic Review and Meta-Analysis of Cohort Studies
CONCLUSION: Overall the evidence from prospective cohort studies supported a link between CO exposure and an increased dementia risk, although all the included studies were limited to Taiwanese population.PMID:38695039 | DOI:10.30773/pi.2021.0134 (Source: Psychiatry Investigation)
Source: Psychiatry Investigation - May 2, 2024 Category: Psychiatry Authors: Meixian Zhang Zhu Liduzi Jiesisibieke Ho-Shan Wei Pei-En Chen Ching-Wen Chien Ping Tao Tao-Hsin Tung Source Type: research
