Enhanced treatment of acute organophosphorus pesticide poisoning using activated charcoal-embedded sodium alginate-polyvinyl alcohol hydrogel
CONCLUSION: The findings suggest that activated charcoal embedded within SA-PVA hydrogel has significant potential as a therapeutic agent in treating AOPP, and offering a novel approach to managing pesticide-induced toxicity.PMID:38607746 | DOI:10.3233/BME-240007 (Source: Bio-Medical Materials and Engineering)
Source: Bio-Medical Materials and Engineering - April 12, 2024 Category: Materials Science Authors: Li Yan Ying Peng Source Type: research

Enhanced treatment of acute organophosphorus pesticide poisoning using activated charcoal-embedded sodium alginate-polyvinyl alcohol hydrogel
CONCLUSION: The findings suggest that activated charcoal embedded within SA-PVA hydrogel has significant potential as a therapeutic agent in treating AOPP, and offering a novel approach to managing pesticide-induced toxicity.PMID:38607746 | DOI:10.3233/BME-240007 (Source: Bio-Medical Materials and Engineering)
Source: Bio-Medical Materials and Engineering - April 12, 2024 Category: Materials Science Authors: Li Yan Ying Peng Source Type: research

Enhanced treatment of acute organophosphorus pesticide poisoning using activated charcoal-embedded sodium alginate-polyvinyl alcohol hydrogel
CONCLUSION: The findings suggest that activated charcoal embedded within SA-PVA hydrogel has significant potential as a therapeutic agent in treating AOPP, and offering a novel approach to managing pesticide-induced toxicity.PMID:38607746 | DOI:10.3233/BME-240007 (Source: Bio-Medical Materials and Engineering)
Source: Bio-Medical Materials and Engineering - April 12, 2024 Category: Materials Science Authors: Li Yan Ying Peng Source Type: research

Vertical Cross ‐Alignments of 2D Semiconductors with Steered Internal Electric Field for Urea Electrooxidation via Balancing Intermediates Adsorption
Cross-alignment of in situ vertically grown Ni(OH)2 nanosheets on 2D semiconductor g-C3N4 forms the steered internal electric field to enhance adsorption of urea, thus efficiently avoid poisoning of strongly adsorbed OH− during urea oxidation reaction (UOR). The balanced adsorption of urea and OH− results in accelerated reaction kinetics and excellent selectivity for UOR, even at high potentials. AbstractSingle-component electrocatalysts generally lead to unbalanced adsorption of OH− and urea during urea oxidation reaction (UOR), thus obtaining low activity and selectivity especially when oxygen evolution reaction (O...
Source: Small - April 10, 2024 Category: Nanotechnology Authors: Hanxiao Du, Huashuai Hu, Xunlu Wang, Nian Ran, Wei Chen, Hongbo Zhu, Yin Zhou, Minghui Yang, Jiacheng Wang, Jianjun Liu Tags: Research Article Source Type: research

Exposure assessment and risk characterisation of aflatoxins in randomly collected rice samples from local markets of Hyderabad, India
This study revealed an adverse health risk to population of Hyderabad due to consumption of AF contaminated rice.PMID:38598120 | DOI:10.1080/19440049.2024.2339369 (Source: Cancer Control)
Source: Cancer Control - April 10, 2024 Category: Cancer & Oncology Authors: Vakdevi Validandi Srinivasu Kurella Sumitra Gorain Yamuna Sagubandi Sathish Kumar Mungamuri Sukesh Narayan Sinha Source Type: research

Respiratory paralysis in a patient with myasthenia gravis after ingestion of marine carnivorous gastropods: A case report
Intern Med. 2024 Apr 9. doi: 10.2169/internalmedicine.2828-23. Online ahead of print.ABSTRACTThe salivary glands of marine carnivorous gastropods contain tetramines, which usually cause mild symptoms of poisoning. However, these symptoms may be fatal in rare cases. A 58-year-old woman with a history of myasthenia gravis complained of dyspnea after consuming marine carnivorous gastropods with intact salivary glands. Upon arrival at the hospital, her blood gas analysis revealed type II respiratory failure with a pCO2 of 154 mmHg. Tracheal intubation was immediately performed. Her respiratory condition improved the following ...
Source: Internal Medicine - April 10, 2024 Category: Internal Medicine Authors: Kenji Inoue Masatsugu Hasegawa Ryosuke Sato Michio Kobayashi Source Type: research

Bioremediation and Bioscavenging for elimination of Organophosphorus threats: An approach using enzymatic advancements
Environ Res. 2024 Apr 8:118888. doi: 10.1016/j.envres.2024.118888. Online ahead of print.ABSTRACTOrganophosphorus compounds (OP) are highly toxic pesticides and nerve agents widely used in agriculture and chemical warfare. The extensive use of these chemicals has severe environmental implications, such as contamination of soil, water bodies, and food chains, thus endangering ecosystems and biodiversity. Plants absorb pesticide residues, which then enter the food chain and accumulate in the body fat of both humans and animals. Numerous human cases of OP poisoning have been linked to both acute and long-term exposure to thes...
Source: Environmental Research - April 10, 2024 Category: Environmental Health Authors: Surbhi Jaiswal Brijeshwar Singh Isha Dhingra Abhijeet Joshi Prashant Kodgire Source Type: research

Reactive oxygen species impair Na+ transport and renal components of the renin-angiotensin-aldosterone system after paraquat poisoning
This study evaluated how ROS acutely influences Na+-transporting ATPases and the renal RAAS. Adult male Wistar rats received paraquat (20 mg/kg; ip). After 24 h, we observed body weight loss and elevation of urinary flow and serum creatinine. In the renal cortex, paraquat increased ROS levels, NADPH oxidase and (Na++K+)ATPase activities, angiotensin II-type 1 receptors, tumor necrosis factor-α (TNF-α), and interleukin-6. In the medulla, paraquat increased ROS levels and NADPH oxidase activity but inhibited (Na++K+)ATPase. Paraquat induced opposite effects on the ouabain-resistant Na+-ATPase in the cortex (decrease) and m...
Source: An Acad Bras Cienc - April 10, 2024 Category: Science Authors: Marry A S Cirilo Val éria B S Santos Nat ália K S Lima Humberto Muzi-Filho Ana D O Paix ão Adalberto Vieyra Leucio D Vieira Source Type: research

Respiratory paralysis in a patient with myasthenia gravis after ingestion of marine carnivorous gastropods: A case report
Intern Med. 2024 Apr 9. doi: 10.2169/internalmedicine.2828-23. Online ahead of print.ABSTRACTThe salivary glands of marine carnivorous gastropods contain tetramines, which usually cause mild symptoms of poisoning. However, these symptoms may be fatal in rare cases. A 58-year-old woman with a history of myasthenia gravis complained of dyspnea after consuming marine carnivorous gastropods with intact salivary glands. Upon arrival at the hospital, her blood gas analysis revealed type II respiratory failure with a pCO2 of 154 mmHg. Tracheal intubation was immediately performed. Her respiratory condition improved the following ...
Source: Internal Medicine - April 10, 2024 Category: Internal Medicine Authors: Kenji Inoue Masatsugu Hasegawa Ryosuke Sato Michio Kobayashi Source Type: research

Bioremediation and Bioscavenging for elimination of Organophosphorus threats: An approach using enzymatic advancements
Environ Res. 2024 Apr 8:118888. doi: 10.1016/j.envres.2024.118888. Online ahead of print.ABSTRACTOrganophosphorus compounds (OP) are highly toxic pesticides and nerve agents widely used in agriculture and chemical warfare. The extensive use of these chemicals has severe environmental implications, such as contamination of soil, water bodies, and food chains, thus endangering ecosystems and biodiversity. Plants absorb pesticide residues, which then enter the food chain and accumulate in the body fat of both humans and animals. Numerous human cases of OP poisoning have been linked to both acute and long-term exposure to thes...
Source: Environmental Research - April 10, 2024 Category: Environmental Health Authors: Surbhi Jaiswal Brijeshwar Singh Isha Dhingra Abhijeet Joshi Prashant Kodgire Source Type: research

Reactive oxygen species impair Na+ transport and renal components of the renin-angiotensin-aldosterone system after paraquat poisoning
This study evaluated how ROS acutely influences Na+-transporting ATPases and the renal RAAS. Adult male Wistar rats received paraquat (20 mg/kg; ip). After 24 h, we observed body weight loss and elevation of urinary flow and serum creatinine. In the renal cortex, paraquat increased ROS levels, NADPH oxidase and (Na++K+)ATPase activities, angiotensin II-type 1 receptors, tumor necrosis factor-α (TNF-α), and interleukin-6. In the medulla, paraquat increased ROS levels and NADPH oxidase activity but inhibited (Na++K+)ATPase. Paraquat induced opposite effects on the ouabain-resistant Na+-ATPase in the cortex (decrease) and m...
Source: An Acad Bras Cienc - April 10, 2024 Category: Science Authors: Marry A S Cirilo Val éria B S Santos Nat ália K S Lima Humberto Muzi-Filho Ana D O Paix ão Adalberto Vieyra Leucio D Vieira Source Type: research

Reactive oxygen species impair Na+ transport and renal components of the renin-angiotensin-aldosterone system after paraquat poisoning
This study evaluated how ROS acutely influences Na+-transporting ATPases and the renal RAAS. Adult male Wistar rats received paraquat (20 mg/kg; ip). After 24 h, we observed body weight loss and elevation of urinary flow and serum creatinine. In the renal cortex, paraquat increased ROS levels, NADPH oxidase and (Na++K+)ATPase activities, angiotensin II-type 1 receptors, tumor necrosis factor-α (TNF-α), and interleukin-6. In the medulla, paraquat increased ROS levels and NADPH oxidase activity but inhibited (Na++K+)ATPase. Paraquat induced opposite effects on the ouabain-resistant Na+-ATPase in the cortex (decrease) and m...
Source: An Acad Bras Cienc - April 10, 2024 Category: Science Authors: Marry A S Cirilo Val éria B S Santos Nat ália K S Lima Humberto Muzi-Filho Ana D O Paix ão Adalberto Vieyra Leucio D Vieira Source Type: research

Respiratory paralysis in a patient with myasthenia gravis after ingestion of marine carnivorous gastropods: A case report
Intern Med. 2024 Apr 9. doi: 10.2169/internalmedicine.2828-23. Online ahead of print.ABSTRACTThe salivary glands of marine carnivorous gastropods contain tetramines, which usually cause mild symptoms of poisoning. However, these symptoms may be fatal in rare cases. A 58-year-old woman with a history of myasthenia gravis complained of dyspnea after consuming marine carnivorous gastropods with intact salivary glands. Upon arrival at the hospital, her blood gas analysis revealed type II respiratory failure with a pCO2 of 154 mmHg. Tracheal intubation was immediately performed. Her respiratory condition improved the following ...
Source: Internal Medicine - April 10, 2024 Category: Internal Medicine Authors: Kenji Inoue Masatsugu Hasegawa Ryosuke Sato Michio Kobayashi Source Type: research

Reactive oxygen species impair Na+ transport and renal components of the renin-angiotensin-aldosterone system after paraquat poisoning
This study evaluated how ROS acutely influences Na+-transporting ATPases and the renal RAAS. Adult male Wistar rats received paraquat (20 mg/kg; ip). After 24 h, we observed body weight loss and elevation of urinary flow and serum creatinine. In the renal cortex, paraquat increased ROS levels, NADPH oxidase and (Na++K+)ATPase activities, angiotensin II-type 1 receptors, tumor necrosis factor-α (TNF-α), and interleukin-6. In the medulla, paraquat increased ROS levels and NADPH oxidase activity but inhibited (Na++K+)ATPase. Paraquat induced opposite effects on the ouabain-resistant Na+-ATPase in the cortex (decrease) and m...
Source: An Acad Bras Cienc - April 10, 2024 Category: Science Authors: Marry A S Cirilo Val éria B S Santos Nat ália K S Lima Humberto Muzi-Filho Ana D O Paix ão Adalberto Vieyra Leucio D Vieira Source Type: research

Reactive oxygen species impair Na+ transport and renal components of the renin-angiotensin-aldosterone system after paraquat poisoning
This study evaluated how ROS acutely influences Na+-transporting ATPases and the renal RAAS. Adult male Wistar rats received paraquat (20 mg/kg; ip). After 24 h, we observed body weight loss and elevation of urinary flow and serum creatinine. In the renal cortex, paraquat increased ROS levels, NADPH oxidase and (Na++K+)ATPase activities, angiotensin II-type 1 receptors, tumor necrosis factor-α (TNF-α), and interleukin-6. In the medulla, paraquat increased ROS levels and NADPH oxidase activity but inhibited (Na++K+)ATPase. Paraquat induced opposite effects on the ouabain-resistant Na+-ATPase in the cortex (decrease) and m...
Source: An Acad Bras Cienc - April 10, 2024 Category: Science Authors: Marry A S Cirilo Val éria B S Santos Nat ália K S Lima Humberto Muzi-Filho Ana D O Paix ão Adalberto Vieyra Leucio D Vieira Source Type: research