Electrochemical Nitrogen Reduction to Ammonia at Ambient Condition on the (111) Facets of Transition Metal Carbonitrides
Chemphyschem. 2024 Apr 3:e202300991. doi: 10.1002/cphc.202300991. Online ahead of print.ABSTRACTWe conducted ab-initio calculations to investigate a class of materials with the goal of enabling nitrogen activation and electrochemical ammonia production under ambient conditions. The source of protons at the anode could originate from either water splitting or H2, but our specific focus was on the cathode reaction, where nitrogen is reduced into ammonia. The conventional associative, dissociative, and Mars-van Krevelen mechanisms were investigated on the (111) facets of a range of metal carbonitrides. We explored the catalyt...
Source: Chemphyschem - April 3, 2024 Category: Chemistry Authors: Atef Iqbal Egill Sk úlason Younes Abghoui Source Type: research
Acute death as a result of poisoning tropical (Bos taurus indicus) but not temperate (Bos taurus taurus) cattle after oral dosing with Lupinus leucophyllus (velvet lupine)
Toxicon. 2024 Apr 1:107706. doi: 10.1016/j.toxicon.2024.107706. Online ahead of print.ABSTRACTDue to climate change and increasing summer temperatures, tropical cattle may graze where temperate cattle have grazed, exposing tropical cattle to toxic plants they may be unfamiliar with. This work compared the toxicity of Lupinus leucophyllus (velvet lupine) in temperate and tropical cattle. Orally dosed velvet lupine in tropical cattle caused death. If producers opt to graze tropical cattle, additional care must be taken on rangelands where toxic lupines like velvet lupine grow.PMID:38570167 | DOI:10.1016/j.toxicon.2024.107706 (Source: Toxicon)
Source: Toxicon - April 3, 2024 Category: Toxicology Authors: Benedict T Green Kevin D Welch Stephen T Lee T Zane Davis Clinton A Stonecipher Bryan L Stegelmeier Daniel Cook Source Type: research
Effects of arsenic exposure on blood trace element levels in rats and sex differences
In this study, a rat model of As poisoning was established to investigate the levels of trace elements in the blood of rats and sex differences in the effect of As on every trace elements in rat blood. Twenty 6-week-old SD (Sprague Dawley) rats were randomly divided into the control group and the As-exposed group. After 3 months, the contents of 19 elements including As in the blood were detected in these two groups by inductively coupled plasma mass spectrometry (ICP-MS). As levels in the blood of As-exposed rats were significantly higher than those in the control group, with increased levels of Rb, Sr, Cs and Ce, and dec...
Source: Biometals - April 3, 2024 Category: Biochemistry Authors: Xiaoqian Ran Xi Yan Hongbin Zhuang Zhiyuan Liang Guanwei Ma Xiaolu Chen Yuhan Huang Xukun Liu Peng Luo Ting Hu Jun Zhang Liming Shen Source Type: research
Facile construction of sandwich ELISA based on double-nanobody for specific detection of α-hemolysin in food samples
Talanta. 2024 Apr 1;274:126021. doi: 10.1016/j.talanta.2024.126021. Online ahead of print.ABSTRACTα-hemolysin (Hla), a toxin secreted by Staphylococcus aureus (S. aureus), has been proved to be involved in the occurrence and aggravation of food poisoning. Hence, it is quite essential to establish its rapid detection methods to guarantee food safety. Sandwich ELISA based on nanobody is well known to be viable for toxins, but there is absence of nanobody against Hla, let alone a pair for it. Therefore, in this paper, we screened specific nanobodies by bio-panning and obtained the optimal nanobody pair for sandwich ELISA fir...
Source: Talanta - April 3, 2024 Category: Chemistry Authors: Yao Zhang Ting Wang Pengfei Zhang Yangli Wan Guanhong Chang Xu Xu Fuqian Ruan Ting Zhou Qin Zhao Min Zhang Xin Wang Source Type: research
Investigating bleeding adverse events associated with BTK inhibitors in the Food and Drug Administration adverse event reporting system (FAERS)
CONCLUSION: Our findings indicate that bleeding AEs linked to BTK inhibitors in various conditions underscore the need for cautious clinical decision-making, particularly in nervous system disorders, injuries, poisoning, surgical complications, vascular disorders, and others.PMID:38568245 | DOI:10.1080/14740338.2024.2339448 (Source: Expert Opinion on Drug Safety)
Source: Expert Opinion on Drug Safety - April 3, 2024 Category: Drugs & Pharmacology Authors: Xianlin Li Nan Shang Qianci Yan Xiunan Yue Yang Liu Xiaojun Zheng Source Type: research
Protobothrops jerdonii (Jerdon's pit-viper) and Protobothrops himalayanus bites: Clinical report on envenomings from North-East India, managed through remote consultation by a national-level Poison control center
Toxicon. 2024 Mar 31:107704. doi: 10.1016/j.toxicon.2024.107704. Online ahead of print.ABSTRACTMembers of the genus Protobothrops are amongst the more than twenty-eight range-restricted Indian pit-viper species. Their bites and envenomings are rarely documented from India. Pit-viper envenomings can be challenging to treat in the Indian setting, since available antivenoms do not satisfactorily neutralize their venoms. Herein, we present the first Indian reports on bites and envenoming by Protobothrops jerdonii and Protobothrops himalayanus resulting in local effects, coagulopathy and acute kidney injury in the case of the f...
Source: Toxicon - April 2, 2024 Category: Toxicology Authors: Ravikar Ralph Deepak Sharma Rohit Jain Amith Balachandran Yu-Wei Chiang Ganesh S R Source Type: research
Protobothrops jerdonii (Jerdon's pit-viper) and Protobothrops himalayanus bites: Clinical report on envenomings from North-East India, managed through remote consultation by a national-level Poison control center
Toxicon. 2024 Mar 31:107704. doi: 10.1016/j.toxicon.2024.107704. Online ahead of print.ABSTRACTMembers of the genus Protobothrops are amongst the more than twenty-eight range-restricted Indian pit-viper species. Their bites and envenomings are rarely documented from India. Pit-viper envenomings can be challenging to treat in the Indian setting, since available antivenoms do not satisfactorily neutralize their venoms. Herein, we present the first Indian reports on bites and envenoming by Protobothrops jerdonii and Protobothrops himalayanus resulting in local effects, coagulopathy and acute kidney injury in the case of the f...
Source: Toxicon - April 2, 2024 Category: Toxicology Authors: Ravikar Ralph Deepak Sharma Rohit Jain Amith Balachandran Yu-Wei Chiang Ganesh S R Source Type: research
Pediatric poisoning management: How clinical practice can benefit from forensic approach
J Forensic Sci. 2024 Apr 1. doi: 10.1111/1556-4029.15517. Online ahead of print.ABSTRACTPediatric population represents the most vulnerable and at risk for unintentional poisoning, with children younger than 6 years old accounting for nearly half of poison exposures. Poisoning is a time-dependent emergency. The need to reach a scientific agreement on diagnostic protocol and treatment seems to be crucial to reduce morbidity and mortality. Starting from a buprenorphine pediatric intoxication case, this article highlights the limits and pitfalls of the traditional diagnostic approach. Diagnosis of drug intoxication was achiev...
Source: Journal of Forensic Sciences - April 1, 2024 Category: Forensic Medicine Authors: Pascale Basilicata Mariagrazia Marisei Rossella Guadagni Michelina Sibilio Massimo Niola Maria Pieri Source Type: research
In patients with coma due to acute poisoning, withholding intubation improved clinical outcomes
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0011. Online ahead of print.ABSTRACTFreund Y, Viglino D, Cachanado M, et al. Effect of noninvasive airway management of comatose patients with acute poisoning: a randomized clinical trial. JAMA. 2023;330:2267-2274. 38019968.PMID:38560902 | DOI:10.7326/J24-0011 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Evan S Schwarz Source Type: research
Pediatric poisoning management: How clinical practice can benefit from forensic approach
J Forensic Sci. 2024 Apr 1. doi: 10.1111/1556-4029.15517. Online ahead of print.ABSTRACTPediatric population represents the most vulnerable and at risk for unintentional poisoning, with children younger than 6 years old accounting for nearly half of poison exposures. Poisoning is a time-dependent emergency. The need to reach a scientific agreement on diagnostic protocol and treatment seems to be crucial to reduce morbidity and mortality. Starting from a buprenorphine pediatric intoxication case, this article highlights the limits and pitfalls of the traditional diagnostic approach. Diagnosis of drug intoxication was achiev...
Source: Journal of Forensic Sciences - April 1, 2024 Category: Forensic Medicine Authors: Pascale Basilicata Mariagrazia Marisei Rossella Guadagni Michelina Sibilio Massimo Niola Maria Pieri Source Type: research
In patients with coma due to acute poisoning, withholding intubation improved clinical outcomes
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0011. Online ahead of print.ABSTRACTFreund Y, Viglino D, Cachanado M, et al. Effect of noninvasive airway management of comatose patients with acute poisoning: a randomized clinical trial. JAMA. 2023;330:2267-2274. 38019968.PMID:38560902 | DOI:10.7326/J24-0011 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Evan S Schwarz Source Type: research
Pediatric poisoning management: How clinical practice can benefit from forensic approach
J Forensic Sci. 2024 Apr 1. doi: 10.1111/1556-4029.15517. Online ahead of print.ABSTRACTPediatric population represents the most vulnerable and at risk for unintentional poisoning, with children younger than 6 years old accounting for nearly half of poison exposures. Poisoning is a time-dependent emergency. The need to reach a scientific agreement on diagnostic protocol and treatment seems to be crucial to reduce morbidity and mortality. Starting from a buprenorphine pediatric intoxication case, this article highlights the limits and pitfalls of the traditional diagnostic approach. Diagnosis of drug intoxication was achiev...
Source: Journal of Forensic Sciences - April 1, 2024 Category: Forensic Medicine Authors: Pascale Basilicata Mariagrazia Marisei Rossella Guadagni Michelina Sibilio Massimo Niola Maria Pieri Source Type: research
In patients with coma due to acute poisoning, withholding intubation improved clinical outcomes
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0011. Online ahead of print.ABSTRACTFreund Y, Viglino D, Cachanado M, et al. Effect of noninvasive airway management of comatose patients with acute poisoning: a randomized clinical trial. JAMA. 2023;330:2267-2274. 38019968.PMID:38560902 | DOI:10.7326/J24-0011 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Evan S Schwarz Source Type: research
In patients with coma due to acute poisoning, withholding intubation improved clinical outcomes
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0011. Online ahead of print.ABSTRACTFreund Y, Viglino D, Cachanado M, et al. Effect of noninvasive airway management of comatose patients with acute poisoning: a randomized clinical trial. JAMA. 2023;330:2267-2274. 38019968.PMID:38560902 | DOI:10.7326/J24-0011 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Evan S Schwarz Source Type: research
In patients with coma due to acute poisoning, withholding intubation improved clinical outcomes
Ann Intern Med. 2024 Apr 2. doi: 10.7326/J24-0011. Online ahead of print.ABSTRACTFreund Y, Viglino D, Cachanado M, et al. Effect of noninvasive airway management of comatose patients with acute poisoning: a randomized clinical trial. JAMA. 2023;330:2267-2274. 38019968.PMID:38560902 | DOI:10.7326/J24-0011 (Source: Annals of Internal Medicine)
Source: Annals of Internal Medicine - April 1, 2024 Category: Internal Medicine Authors: Evan S Schwarz Source Type: research
