Spontaneous regression of acute fibrinous organizing pneumonia induced by COVID-19 vaccination: A case report
Respir Investig. 2024 Feb 28;62(3):356-359. doi: 10.1016/j.resinv.2024.01.014. Online ahead of print.ABSTRACTA 42-year-old woman visited our hospital with complaints of fever, muscle pain, and dyspnea one week after receiving the coronavirus disease 2019 (COVID-19) vaccine. Chest high-resolution computed tomography showed a patchy consolidation and ground-glass attenuation in the both lungs, consistent with acute interstitial pneumonia. Transbronchial lung cryobiopsy revealed organizing pneumonia with marked intra-alveolar fibrin, and pathologically diagnosed as acute fibrinous organizing pneumonia (AFOP). Other causative ...
Source: Pain Physician - February 29, 2024 Category: Anesthesiology Authors: Sanshiro Haga Ryota Otoshi Akimasa Sekine Taichi Kaneko Chieri Yamada Tomohisa Baba Shigeru Komatsu Tomoe Sawazumi Tamiko Takemura Takashi Ogura Source Type: research

Co-administration of the adjuvanted recombinant zoster vaccine with other adult vaccines: An overview
CONCLUSIONS: Co-administration of RZV with routine vaccines does not significantly alter the reactogenicity, immunogenicity or safety of RZV or the co-administered vaccine. Healthcare practitioners should consider routine co-administration of RZV with other adult vaccines to improve vaccination coverage.PMID:38423814 | DOI:10.1016/j.vaccine.2024.02.035 (Source: Herpes)
Source: Herpes - February 29, 2024 Category: Infectious Diseases Authors: S Omar Ali Christophe Dessart Raunak Parikh Source Type: research

Spontaneous regression of acute fibrinous organizing pneumonia induced by COVID-19 vaccination: A case report
Respir Investig. 2024 Feb 28;62(3):356-359. doi: 10.1016/j.resinv.2024.01.014. Online ahead of print.ABSTRACTA 42-year-old woman visited our hospital with complaints of fever, muscle pain, and dyspnea one week after receiving the coronavirus disease 2019 (COVID-19) vaccine. Chest high-resolution computed tomography showed a patchy consolidation and ground-glass attenuation in the both lungs, consistent with acute interstitial pneumonia. Transbronchial lung cryobiopsy revealed organizing pneumonia with marked intra-alveolar fibrin, and pathologically diagnosed as acute fibrinous organizing pneumonia (AFOP). Other causative ...
Source: Pain Physician - February 29, 2024 Category: Anesthesiology Authors: Sanshiro Haga Ryota Otoshi Akimasa Sekine Taichi Kaneko Chieri Yamada Tomohisa Baba Shigeru Komatsu Tomoe Sawazumi Tamiko Takemura Takashi Ogura Source Type: research

Co-administration of the adjuvanted recombinant zoster vaccine with other adult vaccines: An overview
CONCLUSIONS: Co-administration of RZV with routine vaccines does not significantly alter the reactogenicity, immunogenicity or safety of RZV or the co-administered vaccine. Healthcare practitioners should consider routine co-administration of RZV with other adult vaccines to improve vaccination coverage.PMID:38423814 | DOI:10.1016/j.vaccine.2024.02.035 (Source: Vaccine)
Source: Vaccine - February 29, 2024 Category: Allergy & Immunology Authors: S Omar Ali Christophe Dessart Raunak Parikh Source Type: research

Ongoing measles outbreak, the Federation of Bosnia and Herzegovina, December 2023 to February 2024
We report on an ongoing measles outbreak in the Federation of Bosnia and Herzegovina with 141 cases notified between week 52 2023 and week 6 2024. Among those with known vaccination status, 97% were unvaccinated and the most affected group is children under the age of 5 years (n = 87) who were not vaccinated during the pandemic years. Sixty-eight cases were hospitalised, the most common complications were measles-related pneumonia and diarrhoea. The sequenced measles viruses from four cases belonged to genotype D8. (Source: Eurosurveillance)
Source: Eurosurveillance - February 29, 2024 Category: Infectious Diseases Authors: Sanjin Musa, Irma Salimovi ć-Bešić, Jasmina Brkić Džambić, Nijaz Tihić, Anisa Bajramović, Suzana Arapčić, Amela Dedeić-Ljubović and Siniša Skočibušić Source Type: research

High diversity within and low but significant genetic differentiation among geographic and temporal populations of the global Streptococcus pneumoniae
In this study, we investigated the spatial and temporal patterns of genetic variation of S. pneumoniae based on archived multilocus sequence typing data from PubMLST.org. Our analyses demonstrated both shared and unique distributions of sequence types (STs) and allele types among regional populations. Among the 17  915 global STs, 36 representing 15 263 isolates were broadly shared among all six continents, consistent with recent clonal dispersal and expansion of this pathogen. The analysis of molecular variance revealed that >96% genetic variations were found within individual regional populations. However, though...
Source: Canadian Journal of Microbiology - February 29, 2024 Category: Microbiology Authors: Jezreel Dalmieda Megan Hitchcock Jianping Xu Source Type: research

A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection
Cell Host Microbe. 2024 Feb 21:S1931-3128(24)00037-4. doi: 10.1016/j.chom.2024.02.002. Online ahead of print.ABSTRACTSeveral vaccines targeting bacterial pathogens show reduced efficacy upon concurrent viral infection, indicating that a new vaccinology approach is required. To identify antigens for the human pathogen Streptococcus pneumoniae that are effective following influenza infection, we performed CRISPRi-seq in a murine model of superinfection and identified the conserved lafB gene as crucial for virulence. We show that LafB is a membrane-associated, intracellular protein that catalyzes the formation of galactosyl-g...
Source: Cell Host and Microbe - February 28, 2024 Category: Microbiology Authors: Xue Liu Laurye Van Maele Laura Matarazzo Daphn ée Soulard Vinicius Alves Duarte da Silva Vincent de Bakker Julien D énéréaz Florian P Bock Michael Taschner Jinzhao Ou Stephan Gruber Victor Nizet Jean-Claude Sirard Jan-Willem Veening Source Type: research

A conserved antigen induces respiratory Th17-mediated broad serotype protection against pneumococcal superinfection
Cell Host Microbe. 2024 Feb 21:S1931-3128(24)00037-4. doi: 10.1016/j.chom.2024.02.002. Online ahead of print.ABSTRACTSeveral vaccines targeting bacterial pathogens show reduced efficacy upon concurrent viral infection, indicating that a new vaccinology approach is required. To identify antigens for the human pathogen Streptococcus pneumoniae that are effective following influenza infection, we performed CRISPRi-seq in a murine model of superinfection and identified the conserved lafB gene as crucial for virulence. We show that LafB is a membrane-associated, intracellular protein that catalyzes the formation of galactosyl-g...
Source: Cell Host and Microbe - February 28, 2024 Category: Microbiology Authors: Xue Liu Laurye Van Maele Laura Matarazzo Daphn ée Soulard Vinicius Alves Duarte da Silva Vincent de Bakker Julien D énéréaz Florian P Bock Michael Taschner Jinzhao Ou Stephan Gruber Victor Nizet Jean-Claude Sirard Jan-Willem Veening Source Type: research

How common is otogenic meningitis? A retrospective study in southern Sweden over 18  years
ConclusionAOM is an important cause of meningitis in children and adults. Though bacterial meningitis almost disappeared in children  <  2 years after the introduction of PCV, the incidence of pneumococcal meningitis in adults seems to have increased. (Source: Infection)
Source: Infection - February 28, 2024 Category: Infectious Diseases Source Type: research

Effect of Pneumococcal Conjugate Vaccine on Pneumonia Incidence Rates among Children 2-59 Months of Age, Mongolia, 2015-2021
Emerg Infect Dis. 2024 Mar;30(3):490-498. doi: 10.3201/eid3003.230864.ABSTRACTStarting in June 2016, the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced into the routine immunization program of Mongolia by using a 2+1 dosing schedule, phased by district. We used prospective hospital surveillance to evaluate the vaccine's effect on pneumonia incidence rates among children 2-59 months of age over a 6-year period. Of 17,607 children with pneumonia, overall adjusted incidence rate ratios showed decreased primary endpoint pneumonia, very severe pneumonia, and probable pneumococcal pneumonia until June 2021. Resu...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Claire von Mollendorf Munkhchuluun Ulziibayar Cattram D Nguyen Purevsuren Batsaikhan Bujinlkham Suuri Dashtseren Luvsantseren Dorj Narangerel John de Campo Margaret de Campo Bilegtsaikhan Tsolmon Sodbayar Demberelsuren Eileen M Dunne Catherine Satzke Tuya Source Type: research

Effect of Pneumococcal Conjugate Vaccine on Pneumonia Incidence Rates among Children 2-59 Months of Age, Mongolia, 2015-2021
Emerg Infect Dis. 2024 Mar;30(3):490-498. doi: 10.3201/eid3003.230864.ABSTRACTStarting in June 2016, the 13-valent pneumococcal conjugate vaccine (PCV13) was introduced into the routine immunization program of Mongolia by using a 2+1 dosing schedule, phased by district. We used prospective hospital surveillance to evaluate the vaccine's effect on pneumonia incidence rates among children 2-59 months of age over a 6-year period. Of 17,607 children with pneumonia, overall adjusted incidence rate ratios showed decreased primary endpoint pneumonia, very severe pneumonia, and probable pneumococcal pneumonia until June 2021. Resu...
Source: Emerging Infectious Diseases - February 26, 2024 Category: Infectious Diseases Authors: Claire von Mollendorf Munkhchuluun Ulziibayar Cattram D Nguyen Purevsuren Batsaikhan Bujinlkham Suuri Dashtseren Luvsantseren Dorj Narangerel John de Campo Margaret de Campo Bilegtsaikhan Tsolmon Sodbayar Demberelsuren Eileen M Dunne Catherine Satzke Tuya Source Type: research

The association between influenza vaccination uptake and influenza and pneumonia-associated deaths in the United States
DISCUSSION: These results using a population-level statistical approach provide additional support for the overall effectiveness of the US influenza vaccination program. This reassurance is critical given the importance of ensuring confidence in this life saving program. Future research is needed to expand on our approach using more refined data.PMID:38403498 | DOI:10.1016/j.vaccine.2024.01.089 (Source: Vaccine)
Source: Vaccine - February 25, 2024 Category: Allergy & Immunology Authors: Anthony T Newall Allen L Nazareno David J Muscatello David Boettiger C écile Viboud Lone Simonsen Robin M Turner Source Type: research

The association between influenza vaccination uptake and influenza and pneumonia-associated deaths in the United States
DISCUSSION: These results using a population-level statistical approach provide additional support for the overall effectiveness of the US influenza vaccination program. This reassurance is critical given the importance of ensuring confidence in this life saving program. Future research is needed to expand on our approach using more refined data.PMID:38403498 | DOI:10.1016/j.vaccine.2024.01.089 (Source: Vaccine)
Source: Vaccine - February 25, 2024 Category: Allergy & Immunology Authors: Anthony T Newall Allen L Nazareno David J Muscatello David Boettiger C écile Viboud Lone Simonsen Robin M Turner Source Type: research

Monoclonal Antibodies as a Therapeutic Strategy against Multidrug-Resistant Bacterial Infections in a Post-COVID-19 Era
This article describes the current advantages of antibacterial monoclonal antibodies, the development of associated clinical trials, and some perceived future perspectives and challenges. Further, we anticipate the development of more therapeutic agents to combat drug-resistant bacterial infections as well as to increase the resilience of current or novel agents/strategies.PMID:38398755 | DOI:10.3390/life14020246 (Source: Cancer Control)
Source: Cancer Control - February 24, 2024 Category: Cancer & Oncology Authors: Hsiao-Chun Chen Yu-Ling Pan Ying Chen Tsung-Hsuan Yang Erh-Tung Hsu Yu-Ting Huang Ming-Hsien Chiang Source Type: research