Cost-Effectiveness of 20-Valent Pneumococcal Conjugate Vaccine Among US Children with Underlying Medical Conditions
ConclusionsUse of PCV20 among young children with CMC+ and IC in the USA would reduce the clinical burden of pneumococcal disease and yield overall cost savings from both the US healthcare system and societal perspectives. Higher PCV20 uptake could further reduce the number of pneumococcal disease cases in this population. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - March 16, 2024 Category: Infectious Diseases Source Type: research
Impact of pneumococcal conjugate vaccination on pneumococcal nasopharyngeal carriage in the Gambia: Population-based cross-sectional surveys
CONCLUSIONS: Introduction of PCV was associated with reduced VT pneumococcal carriage in young, and older children, although with substantial residual prevalence. Persisting VT, and non-VT, carriage indicate significant, persistent transmission of pneumococci in the population.PMID:38490820 | DOI:10.1016/j.vaccine.2024.02.066 (Source: Vaccine)
Source: Vaccine - March 15, 2024 Category: Allergy & Immunology Authors: Grant A Mackenzie Ilias Hossain Rasheed Salaudeen Henry Badji Ahmed Manjang Effua Usuf Christian Bottomley Brian Greenwood Philip C Hill Source Type: research
Impact of pneumococcal conjugate vaccination on pneumococcal nasopharyngeal carriage in the Gambia: Population-based cross-sectional surveys
CONCLUSIONS: Introduction of PCV was associated with reduced VT pneumococcal carriage in young, and older children, although with substantial residual prevalence. Persisting VT, and non-VT, carriage indicate significant, persistent transmission of pneumococci in the population.PMID:38490820 | DOI:10.1016/j.vaccine.2024.02.066 (Source: Vaccine)
Source: Vaccine - March 15, 2024 Category: Allergy & Immunology Authors: Grant A Mackenzie Ilias Hossain Rasheed Salaudeen Henry Badji Ahmed Manjang Effua Usuf Christian Bottomley Brian Greenwood Philip C Hill Source Type: research
Impact of pneumococcal conjugate vaccination on pneumococcal nasopharyngeal carriage in the Gambia: Population-based cross-sectional surveys
CONCLUSIONS: Introduction of PCV was associated with reduced VT pneumococcal carriage in young, and older children, although with substantial residual prevalence. Persisting VT, and non-VT, carriage indicate significant, persistent transmission of pneumococci in the population.PMID:38490820 | DOI:10.1016/j.vaccine.2024.02.066 (Source: Vaccine)
Source: Vaccine - March 15, 2024 Category: Allergy & Immunology Authors: Grant A Mackenzie Ilias Hossain Rasheed Salaudeen Henry Badji Ahmed Manjang Effua Usuf Christian Bottomley Brian Greenwood Philip C Hill Source Type: research
Animal models of Klebsiella pneumoniae mucosal infections
In conclusion, the choice of the animal model of K. pneumoniae infection will depend mainly on the questions being addressed by the study, while a better understanding of the interplay between bacterial virulence factors and animal host responses will provide a deeper comprehension of the disease process and aid in the development of effective preventive/therapeutic strategies. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - March 15, 2024 Category: Microbiology Source Type: research
Influenza vaccines may protect against cardiovascular diseases: The evidence is mounting and should be known by the Canadian public health community
The objective of this short commentary is to alert the Canadian public health community and to provide information that could be used at the field level to promote the usefulness of influenza vaccines.PMID:38481651 | PMC:PMC10936748 | DOI:10.14745/ccdr.v49i10a04 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 14, 2024 Category: Infectious Diseases Authors: Philippe De Wals Micha ël Desjardins Source Type: research
Necrotizing pneumonia in children: Report of 25 cases between 2008 and 2018 at a French tertiary care center
CONCLUSION: Future studies are needed to assess the epidemiology of NP in children. Continued surveillance of identified pneumococcal serotypes is essential to document epidemiological changes in the coming years.PMID:38485569 | DOI:10.1016/j.arcped.2023.12.004 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 14, 2024 Category: Pediatrics Authors: Manon Cathalau Marine Michelet Aur élien Rancé Guillaume Martin-Blondel Olivier Abbo Damien Dubois G éraldine Labouret Erick Grouteau Isabelle Claudet Lucas Ricco L éa Roditis Jean-Michel Mansuy Sophie Simon Camille Br éhin Source Type: research
Incidence of pneumococcal disease in children ≤48 months old in the United States: 1998-2019
CONCLUSIONS: Incidence rates of IPD, ACP, and AOM decreased in children with commercial insurance and Medicaid coverage from 1998 to 2019. However, burden of disease remained substantial, with higher annual IRs for IPD and ACP for Medicaid-insured vs. commercially-insured children. IPD and inpatient ACP were most common in the youngest children 0-6 months old, followed by the 7-12-month age group.PMID:38485640 | DOI:10.1016/j.vaccine.2024.03.013 (Source: Vaccine)
Source: Vaccine - March 14, 2024 Category: Allergy & Immunology Authors: Salini Mohanty Nicolae Done Qing Liu Yan Song Travis Wang Katherine Gaburo Eric M Sarpong Meghan White Jessica P Weaver James Signorovitch Thomas Weiss Source Type: research
Influenza vaccines may protect against cardiovascular diseases: The evidence is mounting and should be known by the Canadian public health community
The objective of this short commentary is to alert the Canadian public health community and to provide information that could be used at the field level to promote the usefulness of influenza vaccines.PMID:38481651 | PMC:PMC10936748 | DOI:10.14745/ccdr.v49i10a04 (Source: Can Commun Dis Rep)
Source: Can Commun Dis Rep - March 14, 2024 Category: Infectious Diseases Authors: Philippe De Wals Micha ël Desjardins Source Type: research
Necrotizing pneumonia in children: Report of 25 cases between 2008 and 2018 at a French tertiary care center
CONCLUSION: Future studies are needed to assess the epidemiology of NP in children. Continued surveillance of identified pneumococcal serotypes is essential to document epidemiological changes in the coming years.PMID:38485569 | DOI:10.1016/j.arcped.2023.12.004 (Source: Archives de Pediatrie)
Source: Archives de Pediatrie - March 14, 2024 Category: Pediatrics Authors: Manon Cathalau Marine Michelet Aur élien Rancé Guillaume Martin-Blondel Olivier Abbo Damien Dubois G éraldine Labouret Erick Grouteau Isabelle Claudet Lucas Ricco L éa Roditis Jean-Michel Mansuy Sophie Simon Camille Br éhin Source Type: research
