Vaccines and Dementia: Part II. Efficacy of BCG and Other Vaccines Against Dementia
J Alzheimers Dis. 2024 Feb 19. doi: 10.3233/JAD-231323. Online ahead of print.ABSTRACT There is growing awareness that infections may contribute to the development of senile dementia including Alzheimer's disease (AD), and that immunopotentiation is therefore a legitimate target in the management of diseases of the elderly including AD. In Part I of this work, we provided a historical and molecular background to how vaccines, adjuvants, and their component molecules can elicit broad-spectrum protective effects against diverse agents, culminating in the development of the tuberculosis vaccine strain Bacille Calmette-Guérin...
Source: Herpes - February 23, 2024 Category: Infectious Diseases Authors: Charles L Greenblatt Richard Lathe Source Type: research

Vaccines and Dementia: Part II. Efficacy of BCG and Other Vaccines Against Dementia
J Alzheimers Dis. 2024 Feb 19. doi: 10.3233/JAD-231323. Online ahead of print.ABSTRACT There is growing awareness that infections may contribute to the development of senile dementia including Alzheimer's disease (AD), and that immunopotentiation is therefore a legitimate target in the management of diseases of the elderly including AD. In Part I of this work, we provided a historical and molecular background to how vaccines, adjuvants, and their component molecules can elicit broad-spectrum protective effects against diverse agents, culminating in the development of the tuberculosis vaccine strain Bacille Calmette-Guérin...
Source: Herpes - February 23, 2024 Category: Infectious Diseases Authors: Charles L Greenblatt Richard Lathe Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research

A Different Perspective on the COVID-19 Pandemic: Origin of the Outbreak (Part 1)
Exp Clin Transplant. 2024 Jan;22(Suppl 2):1-14. doi: 10.6002/ect.2023.0074.ABSTRACTIn December 2019, an outbreak caused by novel coronavirus 2019 (COVID-19) started in Wuhan, China. After extensive speculation about a causative agent, a novel betacoronavirus, in the same family as SARS-CoV and MERS-CoV, was identified via next-generation sequencing from samples received from several pneumonia patients. Ribonucleic acid extracted from the patient's bronchoalveolar lavage fluid was used as a template to clone and sequence the genome of SARS-CoV-2. Shortly after, the World Health Organization announced a worldwide pandemic. H...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - February 22, 2024 Category: Transplant Surgery Authors: Antoine Barbari Source Type: research