Peripheral Vascular Disease (PVD) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Novel Angiogenesis Role of GLP-1(32-36) to Rescue Diabetic Ischemic Lower Limbs via GLP-1R-Dependent Glycolysis in Mice
CONCLUSIONS: Our study provides a novel mechanism with which GLP-1(32-36) acts in modulating metabolic reprogramming toward glycolytic flux in partnership with GLP-1R for improved angiogenesis in high glucose-exposed EPCs and T1DM murine models. We propose that GLP-1(32-36) could be used as a monotherapy or add-on therapy with existing treatments for peripheral artery disease.REGISTRATION: URL: www.ebi.ac.uk/metabolights/; Unique identifier: MTBLS9543.PMID:38511325 | DOI:10.1161/ATVBAHA.124.320714 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 21, 2024 Category: Cardiology Authors: Yikai Zhang Shengyao Wang Qiao Zhou Yi Xie Yepeng Hu Weihuan Fang Changxin Yang Zhe Wang Shu Ye Xinyi Wang Chao Zheng Source Type: research

Remnant Cholesterol, Not LDL Cholesterol, Explains Peripheral Artery Disease Risk Conferred by apoB: A Cohort Study
CONCLUSIONS: PAD risk conferred by elevated apoB-containing lipoproteins was explained mainly by elevated remnants, while myocardial infarction risk was explained by both elevated remnants and LDL.PMID:38511326 | DOI:10.1161/ATVBAHA.123.320175 (Source: Arteriosclerosis, Thrombosis and Vascular Biology)
Source: Arteriosclerosis, Thrombosis and Vascular Biology - March 21, 2024 Category: Cardiology Authors: Benjamin N Wadstr öm Kasper M Pedersen Anders B Wulff B ørge G Nordestgaard Source Type: research

Evidence for clinician underprescription of and patient non-adherence to guideline-recommended cardiovascular medications among adults with peripheral artery disease: protocol for a systematic review and meta-analysis
Introduction International guidelines recommend that adults with peripheral artery disease (PAD) be prescribed antiplatelet, statin and antihypertensive medications. However, it is unclear how often people with PAD are underprescribed these drugs, which characteristics predict clinician underprescription of and patient non-adherence to guideline-recommended cardiovascular medications, and whether underprescription and non-adherence are associated with adverse health and health system outcomes. Methods and analysis We will search MEDLINE, EMBASE and Evidence-Based Medicine Reviews from 2006 onwards. Two investigators will ...
Source: BMJ Open - March 21, 2024 Category: General Medicine Authors: de Launay, D., Paquet, M., Kirkham, A. M., Graham, I. D., Fergusson, D. A., Nagpal, S. K., Shorr, R., Grimshaw, J. M., Roberts, D. J. Tags: Open access, Cardiovascular medicine Source Type: research

Podcast on How to Classify Foot Ulcers in People with Diabetes (2023 Update of the IWGDF Guidelines on Classification)
ConclusionAlthough there is no classification that fits all purposes, it is crucial that healthcare professionals standardize the way they characterise diabetes-related foot ulcers and guide their decision-making process by using validated classification systems. (Source: Diabetes Therapy)
Source: Diabetes Therapy - March 21, 2024 Category: Endocrinology Source Type: research

The Quantitative Impact of Warfarin Versus Factor Xa Inhibitors on Anticoagulation Profiles in Patients With Peripheral Artery Disease Post-Revascularization
Anticoagulants are a mainstay of thromboembolic prevention in patients with cardiovascular disease, including peripheral artery disease (PAD). Newer factor Xa inhibitors are now being widely used in place of warfarin. There is a paucity of data regarding the impact of type of anticoagulant on coagulation parameters. The aim of this study was to quantify differences in coagulation parameters in patients taking warfarin versus factor Xa inhibitors. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Sasha Suarez Ferreira, Ryan Hall, Katherine Morrow, Shiv Patel, Ivy Lee, Fanah Hagos, Nikolaos Zacharias, Kellie Machlus, Anahita Dua Source Type: research

The Impact of Open Versus Endovascular Procedure Choice on Arterial Thrombosis in Peripheral Artery Disease
This study aimed to determine if open versus endovascular revascularization procedure choice impacts thrombotic rates in peripheral arterial disease (PAD) patients. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Shiv Patel Source Type: research

Long-Term Outcomes of Endovascular Femoropopliteal Therapy With and Without Atherectomy for Lower Extremity Arterial Ulcers
Atherectomy for the treatment for peripheral artery disease (PAD) is increasingly utilized in practice. Although the use of atherectomy has increased in the United States, there is still limited data showing its efficacy and durability compared to angioplasty and stenting alone. Our objective was to analyze long-term outcomes in patients suffering from arterial lower extremity ulcers with and without diabetes who underwent endovascular treatment for femoropopliteal disease (with and without atherectomy). (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Neil A. Patel, Rahman Sayed, Evan Lipsitz, James Hu, Shuo Huang, Jeffrey Indes Source Type: research

Severe Intermittent Claudication. Medical Treatment or Primary Percutaneous Intervention?
The objective of this study was to demonstrate that medical treatment is useful in improving severe intermittent claudication (Rutherford 3/Fontaine IIB) in patients with peripheral vascular disease, without primary percutaneous interventions. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Juan I. Pardo, Daniel Paliza, Lisandro Carnero, Sergio Palomeque, Ana Mollon Source Type: research

Association of Hyperemia With Severity of Peripheral Artery Disease
This study explored the potential of NIRS as a diagnostic tool to detect early peripheral artery disease (PAD). We investigated the correlation between NIRS measurements during the vascular occlusion test (VOT) and the ankle-brachial index (ABI) or six-minute walk test (6MWT) in patients with PAD. Our goal was to determine whether NIRS VOT provides measurements of microvascular function that cannot be examined with conventional vascular non-invasive studies. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Houssam Farres, Santh Prakash Lanka, Cesar Rodriguez, Joshua Maraj, Mathew Martenson, Kevin Salimi, Xiuwen Liu, Judy Delp Source Type: research