Peripheral Vascular Disease (PVD) Blogs This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Preventing amputations and saving lives starts with bringing PAD into the 21st century
There’s a condition that is crippling Black and brown communities at a disproportionate rate and causing 400 amputations each day in the U.S. That may sound scary, but the most frightening part? A new consumer survey found that 70 percent of Americans have never heard of the most common vascular disease, peripheral artery disease (PAD) Read more… Preventing amputations and saving lives starts with bringing PAD into the 21st century originally appeared in KevinMD.com. (Source: Kevin, M.D. - Medical Weblog)
Source: Kevin, M.D. - Medical Weblog - April 18, 2024 Category: General Medicine Authors: Anahita Dua, MD, MBA Tags: Conditions Cardiology Source Type: blogs

Fight Aging! Newsletter, February 26th 2024
In conclusion, mTORC1 signaling contributes to the ISC fate decision, enabling regional control of intestinal cell differentiation in response to nutrition. « Back to Top Reviewing the Development of Senotherapeutics to Treat Aging https://www.fightaging.org/archives/2024/02/reviewing-the-development-of-senotherapeutics-to-treat-aging/ Senescent cells accumulate with age and contribute meaningfully to chronic inflammation and degenerative aging. Destroying these cells produces rapid and sizable reversal of age-related diseases in mice, demonstrating that the presence of senescence cells ...
Source: Fight Aging! - February 25, 2024 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

MTTP as a Mediator of the Benefits of Exercise
MTTP is a longevity-associated gene involved in lipid metabolism and correlated with cardiovascular function. Here, researchers use flies to demonstrate that the fly version of MTTP, called mtp, is involved in the mechanisms by which exercise improves long-term cardiac health. It isn't clear as to how exactly MTTP or mtp is involved in the known set of mechanisms important to the pace of aging and cardiovascular health. That sort of deep dive into establishing connections between cellular processes occurs only after numerous studies have demonstrated an interesting correlation, and even then it is a slow and incremental pr...
Source: Fight Aging! - February 22, 2024 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Infection and DKA, then sudden dyspnea while in the ED
To learn more about Occlusion MI, join us in thisFree Webinar on November 27 12 noon US Central Time:Sign up at this link: https://zoom.us/webinar/register/2216945975176/WN_7HuMRHNxREKifGgQvy70lg#/registrationInfection and DKA, then sudden dyspnea while in the EDA 63 year old male with a PMH of CAD and peripheral vascular disease from type 1 DM presented to clinic and was found to have a very high blood sugar and so was sent to the emergency department.Patient stated that he has had glucose over 400 even though he has not missed any doses of insulin. He also endorses fatigue, upset stomach, frequent urination, i...
Source: Dr. Smith's ECG Blog - November 22, 2023 Category: Cardiology Authors: Steve Smith Source Type: blogs

Fight Aging! Newsletter, November 20th 2023
In this study, we attempted to further explain the role, exact mechanism and target of ICA in treating AD from the ferroptosis perspective. We found that ICA could improve the neurobehavioral, memory, and motor abilities of AD mice. It could lower the ferroptosis level and enhance the resistance to oxidative stress. After inhibition of MDM2, ICA could no longer improve the cognitive ability of AD mice, nor could it further inhibit ferroptosis. Network pharmacological analysis revealed that MDM2 might be the target of ICA action. « Back to Top Particulate Air Pollution and Its Effects on the Mechan...
Source: Fight Aging! - November 19, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Endothelial Cell Senescence in Atherosclerosis
Senescent cells accumulate throughout the body with age. They are created constantly due to stresses placed upon cells, and when somatic cells reach the Hayflick limit on replication, and are cleared by the immune system. This process of clearance slows down with age, unfortunately, and so a burden of lingering senescent cells begins to build up. Senescent cells are disruptive to tissue structure and function, even when present in comparatively small numbers relative to other cells in a tissue, as a result of the pro-growth, pro-inflammatory signals that they generate. Atherosclerosis involves the generation of fatt...
Source: Fight Aging! - November 16, 2023 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

Zealous for Wellness: The Ongoing Quest for Standard Measures
The previous articles in this series showed how payers, providers, and digital health companies try to prove that they’re helping to create healthier patients. Sara Shanti, a partner specializing in health care at law firm Sheppard Mullin, says that organizations in the wellness space are searching for strong algorithms. But they also want to ensure that technology leads to, and clearly reflects, improved and worthwhile outcomes. This is not likely to emerge for some time. But this final article looks at how some organizations are filling the gap. Rigor at a Weight Loss Clinic Dr. Brett Osborn, author of the book G...
Source: EMR and HIPAA - November 16, 2023 Category: Information Technology Authors: Andy Oram Tags: AI/Machine Learning Ambulatory Analytics/Big Data Clinical Communication and Patient Experience Health IT Company Healthcare IT Hospital - Health System LTPAC Arcadia Behavior Change behavioral health BPCI Brett Osborn Clinical Source Type: blogs

Gardner Treadmill Protocol
Gardner Treadmill Protocol, also known as Gardner-Skinner Protocol was described in 1991 [1]. It is used mainly in the evaluation of peripheral arterial disease. The seminal article evaluated the effect of handrail support on claudication distance. Handrail support reduces energy cost of treadmill walking, and can affect claudication distance and hemodynamic responses in persons with peripheral vascular disease. Reliability of tests may also be reduced unless same pressure is applied to the handrails over repeated tests. Gardner treadmill protocol is a symptom limited one with progressive graded workload having constant s...
Source: Cardiophile MD - October 6, 2023 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

Outpatient Vascular Care: Good, bad or ugly?
BY ANISH KOKA Filling in the holes of recent stories in the New York Times, and Propublica on the outpatient care of patients with peripheral arterial disease Most have gotten used to egregiously bad coverage of current events that fills the pages of today’s New York Times, but even by their now very low standards a recent telling of a story about peripheral artery disease was very bad. The scintillating allegation by Katie Thomas, Jessica Silver-Greenberg and Robert Gebeloff is that “medical device makers are bankrolling doctors to perform artery clearing procedures that can lead to amputations�...
Source: The Health Care Blog - July 24, 2023 Category: Consumer Health News Authors: Ryan Bose-Roy Tags: Medical Practice Anish Koka Medical Devices Outpatient vascular care Source Type: blogs

Blood Pressure Meds vs Blood Thinners: What ’ s The Difference?
Conclusion In conclusion, while blood pressure medicines and blood thinners are both crucial to heart health, their roles and mechanisms of action are notably distinct. Blood pressure medication works primarily on the vascular system, aiding in reducing blood pressure by relaxing blood vessels or altering the heart’s function. On the other hand, blood thinners target the blood itself, working to prevent the formation of potentially dangerous blood clots. Throughout this article, one thing becomes undeniably clear: the importance of regular consultations with your healthcare provider. When it comes to managing m...
Source: The EMT Spot - July 20, 2023 Category: Emergency Medicine Authors: Michael Rotman, MD, FRCPC, PhD Tags: Blood Pressure Source Type: blogs

Fight Aging! Newsletter, July 17th 2023
In conclusion, the longevity-associated genotype of FLT1 may confer increased lifespan by protecting against mortality risk posed by hypertension. We suggest that FLT1 expression in individuals with longevity genotype boosts vascular endothelial resilience mechanisms to counteract hypertension-related stress in vital organs and tissues. Resistance Exercise Slows the Onset of Pathology in a Mouse Model of Alzheimer's Disease https://www.fightaging.org/archives/2023/07/resistance-exercise-slows-the-onset-of-pathology-in-a-mouse-model-of-alzheimers-disease/ With the caveat that mouse models of Alzheimer'...
Source: Fight Aging! - July 16, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing Efforts to Use Cells and Scaffolds to Regenerate the Heart
The heart is one of the least regenerative tissues in the body. Damage resulting from loss of blood flow during a heart attack leads to scarring and loss of function, rather than any meaningful degree of regeneration. While preventing the atherosclerosis that causes occlusion of blood vessels is the most desirable goal, finding ways to repair a damaged heart is also a high priority for the research community. Many groups have worked towards regenerative therapies based on delivery of cells and scaffolding material, even layers of artificial tissue made by combining the two, but progress has been frustratingly slow. ...
Source: Fight Aging! - July 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fontaine classification for peripheral arterial disease
In Fontaine classification [1,2], Stage I is asymptomatic with incomplete vascular obstruction. Stage II is with mild claudication which is divided into A with claudication distance more than 200 m and B with claudication distance less than 200 m. Stage III is with rest pain and stage IV with necrosis or gangrene in the limb. Rutherford classification classified peripheral arterial disease into acute and chronic limb ischemia [3]. Each is further subdivided into grades and categories based on symptoms, clinical findings, Doppler, ankle brachial index (ABI) and pulse volume recordings. References Fontaine R, Kim M, Kieny ...
Source: Cardiophile MD - November 17, 2022 Category: Cardiology Authors: Johnson Francis Tags: General Cardiology Source Type: blogs

What Are the Symptoms of High Blood Pressure in Women?
ConclusionThe Common Symptoms Of High Blood Pressure In Women Numerous signs and symptoms in women can point to increased blood pressure. Visit your doctor immediately to check your blood pressure if you experience any of the following signs or symptoms. Or read our article on Complete Blood Pressure Chart to understand the elevations. Excessive fatigue One of the major symptoms of high blood pressure is fatigue. Women with this condition often report feeling tired all the time, even when they get a full night’s sleep. Fatigue can make it difficult to concentrate, and simple tasks seem overwhelming. Thi...
Source: The EMT Spot - November 11, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs

Does High Blood Pressure Make You Tired, Sleepy?
This article will help shed light on the link. Quick Summary There is a strong link between feeling tired or sleepy with high blood pressure due to underlying conditions or medication. Kidney disease, arterial disease, and sleep apnea are possible explanations for lethargy with hypertension. Proper treatment and control can reduce the risk of fatigue caused by elevated blood pressure. So, Does High Blood Pressure Make You Feel Tired, Sleepy, or Fatigued? Fatigue and high blood pressure are connected, but they could also be a symptom of underlying causes—for example, hypertension medication...
Source: The EMT Spot - November 8, 2022 Category: Emergency Medicine Authors: Michael Kutryk Tags: Guides Blood Pressure Source Type: blogs