AI-Powered Plaque Classification: Revealing Peripheral  Artery Disease With 9.4 Tesla MRI Histology
Peripheral artery disease (PAD) lesion composition impacts percutaneous vascular interventions (PVIs). Ultrashort echo time (UTE) magnetic resonance imaging (MRI) can differentiate soft (e.g. fat, thrombus) and hard (calcification, dense collagen) tissue. Artificial intelligence (AI) algorithms are valuable for analyzing complex medical imaging datasets. Our feasibility study aimed to semi-automatically differentiate soft/hard components in PAD lesions and assess crossability using 9.4 T MRI images, a custom-made AI-algorithm, and histological samples. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Judit Csore, Christof Karmonik, Alan B. Lumsden, Trisha L. Roy Source Type: research

Association Between the Neutrophil to High-density Lipoprotein Cholesterol Ratio and Peripheral Artery Disease
This study aims to investigate the relationship between NHR and PAD in American adults. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - March 20, 2024 Category: Surgery Authors: Qiaodan Lu Source Type: research

Gut microbiota's causative relationship with peripheral artery disease: a Mendelian randomization study
CONCLUSION: Our findings hint at a causative association between certain gut microbiota and PAD, introducing new avenues for understanding PAD's etiology and developing effective treatments. The observed associations now warrant further validation in varied populations and detailed exploration at finer taxonomic levels.PMID:38505559 | PMC:PMC10948605 | DOI:10.3389/fmicb.2024.1340262 (Source: Atherosclerosis)
Source: Atherosclerosis - March 20, 2024 Category: Cardiology Authors: Yu Tian Guanqun Yao Loren Skudder-Hill Guangyang Xu Yuxuan Qian Feng Tang Qian Wang Qianhui Bao Lei Li Source Type: research

A multi-centre investigation of macrovascular and non-ocular microvascular complications in children and adolescents with diabetes mellitus in southern Ghana
CONCLUSIONS: Macrovascular and non-ocular microvascular complications are common among children and adolescents with diabetes in southern Ghana and are associated with a long duration of diabetes diagnosis, abnormal body mass index, low HDL cholesterol, and triglyceride levels. Therefore, the early institution of regular screening for diabetes-related complications to allow early detection and appropriate management is recommended.FUNDING: University of Ghana Research Fund.PMID:38504754 | PMC:PMC10846650 | DOI:10.4314/gmj.v57i2.2 (Source: Ghana Medical Journal)
Source: Ghana Medical Journal - March 20, 2024 Category: African Health Authors: Josephine Akpalu Vera A Essuman Winfried M Amoaku Benjamin Abaidoo Akye Essuman Charles Hayfron-Benjamin Nana A Barnes Naa N Tagoe George Asare Thomas A Ndanu Benedicta Appiah-Thompson Imelda D-B Ofori-Adjei Adziri H Sackey Source Type: research

Gut microbiota's causative relationship with peripheral artery disease: a Mendelian randomization study
CONCLUSION: Our findings hint at a causative association between certain gut microbiota and PAD, introducing new avenues for understanding PAD's etiology and developing effective treatments. The observed associations now warrant further validation in varied populations and detailed exploration at finer taxonomic levels.PMID:38505559 | PMC:PMC10948605 | DOI:10.3389/fmicb.2024.1340262 (Source: Atherosclerosis)
Source: Atherosclerosis - March 20, 2024 Category: Cardiology Authors: Yu Tian Guanqun Yao Loren Skudder-Hill Guangyang Xu Yuxuan Qian Feng Tang Qian Wang Qianhui Bao Lei Li Source Type: research

A multi-centre investigation of macrovascular and non-ocular microvascular complications in children and adolescents with diabetes mellitus in southern Ghana
CONCLUSIONS: Macrovascular and non-ocular microvascular complications are common among children and adolescents with diabetes in southern Ghana and are associated with a long duration of diabetes diagnosis, abnormal body mass index, low HDL cholesterol, and triglyceride levels. Therefore, the early institution of regular screening for diabetes-related complications to allow early detection and appropriate management is recommended.FUNDING: University of Ghana Research Fund.PMID:38504754 | PMC:PMC10846650 | DOI:10.4314/gmj.v57i2.2 (Source: Ghana Medical Journal)
Source: Ghana Medical Journal - March 20, 2024 Category: African Health Authors: Josephine Akpalu Vera A Essuman Winfried M Amoaku Benjamin Abaidoo Akye Essuman Charles Hayfron-Benjamin Nana A Barnes Naa N Tagoe George Asare Thomas A Ndanu Benedicta Appiah-Thompson Imelda D-B Ofori-Adjei Adziri H Sackey Source Type: research