Peripheral Vascular Disease (PVD) Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Applicability and impact of the COMPASS trial in a Canadian population of patients with atherosclerotic disease
CONCLUSIONS: In a real-world population of 4.4 million adults, there are roughly 20,000 new cases of ASVCD diagnosed yearly, with ∼40% being eligible for the addition of low-dose rivaroxaban therapy to antiplatelet therapy. The theoretical implementation of dual antithrombotic treatment in this population could result in a substantial reduction in cardiovascular morbidity and mortality.PMID:38582637 | DOI:10.1016/j.atherosclerosis.2024.117486 (Source: Atherosclerosis)
Source: Atherosclerosis - April 6, 2024 Category: Cardiology Authors: Robert C Welsh Pishoy Gouda Doug Dover Kevin R Bainey Finlay A McAlister Padma Kaul Source Type: research

Advancements in Omics and Breakthrough Gene Therapies: A Glimpse into the Future of Peripheral Artery Disease
Ann Vasc Surg. 2024 Apr 4:S0890-5096(24)00156-0. doi: 10.1016/j.avsg.2024.01.031. Online ahead of print.ABSTRACTPeripheral artery disease (PAD), a highly prevalent global disease, associates with significant morbidity and mortality in affected patients. Despite progress in endovascular and open revascularization techniques for advanced PAD, these interventions grapple with elevated rates of arterial restenosis and vein graft failure attributed to intimal hyperplasia (IH). Novel multi-omics technologies, coupled with sophisticated analyses tools recently powered by advances in artificial intelligence, have enabled the study...
Source: Atherosclerosis - April 6, 2024 Category: Cardiology Authors: Phillip G Brennan Lucas Mota Tarek Aridi Nyah Patel Patric Liang Christiane Ferran Source Type: research

Dual-pathway Inhibition with Low-dose Aspirin and Rivaroxaban versus Aspirin Monotherapy in Patients with Coronary Artery Disease and Peripheral Artery Disease: Systematic Literature Review and Meta-analysis
Platelet activation and aggregation play a pivotal role in the complex pathophysiological process of atherosclerotic disease, resulting in the formation of an occlusive thrombus.1 Furthermore, platelets modulate the various endothelial and inflammatory processes tha... Dual-pathway Inhibition with Low-dose Aspirin and Rivaroxaban versus Aspirin Monotherapy in Patients with Coronary Artery Disease and Peripheral Artery Disease: Systematic Literature Review and Meta-analysis Platelet activation and aggregation play a pivotal role in the complex pathophysiological process of atherosclerotic disea...
Source: Radcliffe Cardiology - April 4, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Appropriateness of Care Measures: A Novel Approach to Quality
The clinical judgement of a physician is one of the most important aspects of medical quality, yet it is rarely captured with quality measures in use today. We propose a novel approach using individualized physician benchmarking that measures the appropriateness of care that a physician delivers by looking at their practice pattern in a specific clinical situation. A prime application of our novel approach to appropriateness measures is the surgical management of peripheral artery disease and claudication. (Source: Annals of Vascular Surgery)
Source: Annals of Vascular Surgery - April 4, 2024 Category: Surgery Authors: Caitlin W. Hicks, Michael S. Conte, Chen Dun, Martin A. Makary Source Type: research

Medical Optimization of Patients with Symptomatic Peripheral Arterial Disease
Peripheral artery disease (PAD) is a progressive disease associated with the occurrence of major adverse cardiovascular and limb events, and elevated mortality rates. Symptoms of PAD, including claudication and chronic limb threatening ischemia, impair functional capacity and lead to lower quality of life. The focus of current therapies is to minimize symptoms, improve quality of life, and reduce adverse cardiovascular and limb events. Among the medical therapies are antiplatelets, anticoagulants, antihypertensives, cilostazol and pentoxifylline, and novel blood sugar-lowering therapies, plus exercise therapy and smoking c...
Source: Annals of Vascular Surgery - April 4, 2024 Category: Surgery Authors: Abdelrhman Abumoawad, Ross A. Okazaki, Leili Behrooz, Robert T. Eberhardt Source Type: research

Advancements in Omics and Breakthrough Gene Therapies: A Glimpse into the Future of Peripheral Artery Disease
Peripheral artery disease (PAD), a highly prevalent global disease, associates with significant morbidity and mortality in affected patients. Despite progress in endovascular and open revascularization techniques for advanced PAD, these interventions grapple with elevated rates of arterial restenosis and vein graft failure attributed to intimal hyperplasia (IH). Novel multi-omics technologies, coupled with sophisticated analyses tools recently powered by advances in artificial intelligence, have enabled the study of atherosclerosis and intimal hyperplasia with unprecedented single cell and spatial precision. (Source: Annal...
Source: Annals of Vascular Surgery - April 4, 2024 Category: Surgery Authors: Phillip G. Brennan, Lucas Mota, Tarek Aridi, Nyah Patel, Patric Liang, Christiane Ferran Source Type: research

Lessons Learned from Coronary Revascularization Appropriateness Statements for Application to Peripheral Artery Disease
Appropriate Use Criteria (AUC) are evidence-based criteria developed in a methodologically robust manner with the input of expert providers across a wide range of disciplines and practice settings. AUC have been successfully implemented in the diagnosis and management of a wide range of cardiovascular disease processes. AUC have demonstrated clear potential for influencing meaningful change in practice patterns with regards to high-value, high-quality care in cardiovascular pathologies. Potential for similar impact in the management of peripheral artery disease, specifically for patients presenting with intermittent claudi...
Source: Annals of Vascular Surgery - April 4, 2024 Category: Surgery Authors: M. Libby Weaver Source Type: research

Leveraging Artificial Intelligence to Optimize the Care of Peripheral Artery Disease Patients
Peripheral artery disease is a major atherosclerotic disease that is associated with poor outcomes such as limb loss, cardiovascular morbidity, and death. Artificial intelligence has seen increasing integration in medicine, and its various applications can optimize the care of peripheral artery disease patients in diagnosis, predicting patient outcomes, and imaging interpretation. In this review, we introduce various artificial intelligence applications such as natural language processing, supervised machine learning, and deep learning, and we analyze the current literature in which these algorithms have been applied to pe...
Source: Annals of Vascular Surgery - April 4, 2024 Category: Surgery Authors: Jee Hoon Song, Roger T. Tomihama, Daniel Roh, Andrew Cabrera, Alan Dardik, Sharon C. Kiang Source Type: research

Educating Trainees to Treat Peripheral Arterial Disease: Challenges and Opportunities
Educating trainees to treat Peripheral Artery Disease (PAD) carries specific contemporary challenges. The national increase of the prevalence of PAD combined with a significant shortage of vascular surgeons creates a need for concern for future management of this complex disease. Over the past two decades, traditional (5+2) and integrated (0+5) paradigms have fostered trainee annual growth and comparable case distribution and volumes in endovascular and open surgical treatment options have been maintained. (Source: Annals of Vascular Surgery)
Source: Annals of Vascular Surgery - April 4, 2024 Category: Surgery Authors: Anthony Campbell, Hossam Alslaim, Sira Duson, Vincent L. Rowe Source Type: research

A Comprehensive Review on Nanoparticles as Drug Delivery System and Their Role for Management of Hypertension
Curr Pharm Biotechnol. 2024 Apr 2. doi: 10.2174/0113892010291414240322112508. Online ahead of print.ABSTRACTThe current global epidemic of hypertension is not a disease in and of itself but rather a significant risk factor for serious cardiovascular conditions such as peripheral artery disease, heart failure, myocardial infarction, and stroke. Although many medications that work through various mechanisms of action are available on the market in conventional formulations to treat hypertension, these medications face significant difficulties with their bioavailability, dosing, and associated side effects, which significantl...
Source: Current Pharmaceutical Biotechnology - April 3, 2024 Category: Biotechnology Authors: None Prerna Dinesh Chandra Bhatt Khalid Basir Mir Vikash Kumar Sandeep Rathor Source Type: research

Pharmacist optimization of lipid therapy in patients with peripheral vascular disease
CONCLUSION: The addition of a pharmacist consult led to an increase in the percentage of patients discharged on a high-intensity statin and an increase in overall statin intensification.PMID:38567808 | DOI:10.1093/ajhp/zxae097 (Source: American Journal of Health-System Pharmacy : AJHP)
Source: American Journal of Health-System Pharmacy : AJHP - April 3, 2024 Category: Drugs & Pharmacology Authors: Mary-Ashlyn Tucker Andrew Meyer Michael Bitonti Megan Supple Brandon Cain Source Type: research

Lipoprotein Apheresis Alleviates Treatment-Resistant Peripheral Artery Disease Despite the Normal Range of Atherogenic Lipoproteins: The LETS-PAD Study
CONCLUSION: ABI and QOL improved after a series of LA sessions in conventional treatment-resistant PAD patients with controlled serum lipoprotein levels. Increased antioxidative capacity and ameliorated endothelial function were observed after the LA treatment.PMID:38569869 | DOI:10.5551/jat.64639 (Source: Journal of Atherosclerosis and Thrombosis)
Source: Journal of Atherosclerosis and Thrombosis - April 3, 2024 Category: Cardiology Authors: Eiko Ueda Yoshiyuki Toya Hiromichi Wakui Kohei Ishiga Yuki Kawai Ryu Kobayashi Sho Kinguchi Tomohiko Kanaoka Yusuke Saigusa Taro Mikami Yuichiro Yabuki Motohiko Goda Daisuke Machida Takayuki Fujita Kotaro Haruhara Teruyasu Sugano Kengo Azushima Kouichi Ta Source Type: research