Individualising Antithrombotic Strategies for Acute and Chronic Coronary Syndromes
Coronary artery disease (CAD) is associated with the risk of atherothrombotic events and warrants long-term antithrombotic therapy. The standard treatment for CAD patients who present with acute coronary syndrome (ACS) or chronic coronary syndrome (CCS) includes single (SAPT) or dual antiplatelet therapy (DAPT), sometimes in combination with oral anticoagulants (OACs).1,2 However, establi... Individualising Antithrombotic Strategies for Acute and Chronic Coronary Syndromes Coronary artery disease (CAD) is associated with the risk of atherothrombotic events and warrants long-term antithrombotic...
Source: Radcliffe Cardiology - May 13, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Left Atrium: A New Prognostic Marker and Therapeutic Target in Secondary Mitral Regurgitation?
Mitral regurgitation (MR) is one of the most common valvular abnormalities worldwide and the second most common type requiring surgical treatment.1 The heterogeneity of MR has attracted the interest of imagers who have identified the need to implement newer advanced cardiovascular imaging techniques to delineate MV anatomy and understand the underlying pathophysiologic substra... Left Atrium: A New Prognostic Marker and Therapeutic Target in Secondary Mitral Regurgitation? Mitral regurgitation (MR) is one of the most common valvular abnormalities worldwide and the second most common type requi...
Source: Radcliffe Cardiology - May 13, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series
Ventricular arrhythmias (VAs) are a group of potentially fatal electrophysiological alterations, including heart rhythm disorders that cause erratic electrical shocks. They usually occur in patients with heart failure, ischaemic heart disease, hereditary long QT syndrome and catecholaminergic polymorphic ventricular tachycardia syndrome, among o... Cardiac Sympathetic Denervation as a Treatment for Ventricular Arrhythmias Refractory to Conventional Treatment: A Case Series Ventricular arrhythmias (VAs) are a group of potentially fatal electrophysiological alterations, including heart rhythm di...
Source: Radcliffe Cardiology - May 8, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Procedural Results and Long-term Outcome of Chronic Total Occlusion Percutaneous Coronary Intervention in a UK Non-surgical Centre
Outcomes of CTO PCI in a Non-surgical Centre Download Coronary chronic total occlusions (CTOs) are common and found in up to 25% of patients undergoing coronary angiography; ... Procedural Results and Long-term Outcome of Chronic Total Occlusion Percutaneous Coronary Intervention in a UK Non-surgical Centre Outcomes of CTO PCI in a Non-surgical Centre Download Coronary chronic total occlusions (CTOs) are common and...
Source: Radcliffe Cardiology - May 7, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Application of Transcatheter Electrosurgery in Structural Heart Interventions: A Report of Three Different Techniques
Transcatheter electrosurgery refers to the novel technique of traversing or cutting tissue, within blood-filled spaces, using alternating current directed by guidewires and catheters.1 Unlike conventional open surgery, which employs electrosurgery using an electrosurgery pencil in dry, air-filled conditions under direct operator vision, transcatheter ele... Application of Transcatheter Electrosurgery in Structural Heart Interventions: A Report of Three Different Techniques Transcatheter electrosurgery refers to the novel technique of traversing or cutting tissue, within blood-filled spaces, us...
Source: Radcliffe Cardiology - May 6, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Coronary Revascularisation in Heart Failure with Reduced Ejection Fraction
Ischaemic cardiomyopathy (ICM) is the most common cause of heart failure with reduced ejection fraction (HFrEF) and the largest contributing factor of the projected increases in heart failure (HF) incidence worldwide.1,2 The mechanism by which ICM leads to HF is through the development of left ventricular (LV) systolic dysfunction either via acute MI(s) or gradually via a progressive decline in s... Coronary Revascularisation in Heart Failure with Reduced Ejection Fraction Ischaemic cardiomyopathy (ICM) is the most common cause of heart failure with reduced ejection fraction (HFrEF) and the la...
Source: Radcliffe Cardiology - May 6, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Stent Ablation by Rotational Atherectomy for Management of Resistant Lesions within and across the Stent Struts in Coronary Arteries
BackgroundSeverely calcified lesions are associated with increased procedural risks and suboptimal results such as stent underexpansion.1 Stent underexpansion is often related to stent thrombosis and in-stent restenosis (ISR).2 Conventional treatment of native non-dilatable calcified lesions is well established with rotational atherectomy ... Stent Ablation by Rotational Atherectomy for Management of Resistant Lesions within and across the Stent Struts in Coronary Arteries BackgroundSeverely calcified lesions are associated with increased procedural risks and suboptimal results such as stent u...
Source: Radcliffe Cardiology - May 5, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Navigating the Link Between Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis and Cardiometabolic Syndrome
Non-alcoholic fatty liver disease (NAFLD) is characterised by the presence of steatosis in more than 5% of hepatocytes, often associated with metabolic risk factors (particularly obesity and type 2 diabetes), and in the absence of excessive alcohol consumption or other chronic liver diseases.1 NAFLD serves as an umbrella term encompassing a wide range... Navigating the Link Between Non-alcoholic Fatty Liver Disease/Non-alcoholic Steatohepatitis and Cardiometabolic Syndrome Non-alcoholic fatty liver disease (NAFLD) is characterised by the presence of steatosis in more than 5% of hepatocytes, of...
Source: Radcliffe Cardiology - May 4, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Navigating the Link Between Non-alcoholic Fatty Liver Disease/ Non-alcoholic Steatohepatitis and Cardiometabolic Syndrome
Non-alcoholic fatty liver disease (NAFLD) is characterised by the presence of steatosis in more than 5% of hepatocytes, often associated with metabolic risk factors (particularly obesity and type 2 diabetes), and in the absence of excessive alcohol consumption or other chronic liver diseases.1 NAFLD serves as an umbrella term encompassing a wide rang... Navigating the Link Between Non-alcoholic Fatty Liver Disease/ Non-alcoholic Steatohepatitis and Cardiometabolic Syndrome Non-alcoholic fatty liver disease (NAFLD) is characterised by the presence of steatosis in more than 5% of hepatocytes, of...
Source: Radcliffe Cardiology - May 4, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Management of Cardiovascular Risk in the Non ‑alcoholic Fatty Liver Disease Setting
Non-alcoholic fatty liver disease (NAFLD), also named metabolic dysfunction-associated fatty liver disease (MAFLD), is a progressive disease spectrum encompassing simple steatosis, non-alcoholic steatohepatitis, fibrosis and cirrhosis .1 Hepatic steatosis refers to ectopic deposition of triglycerides in the liver. It is necessary to exclude secondary hepatic fat accumulation (heavy alcohol... Management of Cardiovascular Risk in the Non ‑alcoholic Fatty Liver Disease Setting Non-alcoholic fatty liver disease (NAFLD), also named metabolic dysfunction-associated fatty liver disease (MAFLD), is...
Source: Radcliffe Cardiology - May 3, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Spironolactone versus Eplerenone in Patients with Resistant Hypertension: A Systematic Review and Indirect Meta-analysis
Hypertension is one of the main risk factors for cardiovascular diseases, stroke and kidney failure. Approximately 1.28 billion adults worldwide are afflicted by hypertension, predominantly in lower-middle-income countries.1 Among individuals with hypertension, a small subset experience resistant hypertension (RH), a condition that often complicates o... Spironolactone versus Eplerenone in Patients with Resistant Hypertension: A Systematic Review and Indirect Meta-analysis Hypertension is one of the main risk factors for cardiovascular diseases, stroke and kidney failure. Approximately 1.28 bi...
Source: Radcliffe Cardiology - April 23, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Delayed Diagnosis of Right Heart Failure Due to Sinus Venosus Atrial Septal Defect, Persistent Left Superior Vena Cava and Partial Anomalous Pulmonary Venous Return
Atrial septal defects (ASD) are an uncommon cause of right heart failure and pulmonary hypertension. Sinus venosus ASD (SVASD) are an uncommon form of ASD, amounting to 5 –10% of all ASD. They are commonly underdiagnosed as the defects are often located superior and adjacent to the superior vena cava (SVC), w... Delayed Diagnosis of Right Heart Failure Due to Sinus Venosus Atrial Septal Defect, Persistent Left Superior Vena Cava and Partial Anomalous Pulmonary Venous Return Atrial septal defects (ASD) are an uncommon cause of right heart failure and pulmonary hypertension. Sinus venosus ASD ...
Source: Radcliffe Cardiology - April 23, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Asian Pacific Society of Cardiology Consensus Statements on the Diagnosis and Management of Acute MI-Cardiogenic Shock and Endorsed by the Asian Pacific Society of Interventional Cardiology
In the Asia-Pacific region, acute coronary syndrome (ACS) remains a major cause of death and disability, with in-hospital mortality typically exceeding 5%.1 Furthermore, regional data showed that 10 –15% of patients with acute MI (AMI) develop cardiogenic shock (CS), which was associa... Asian Pacific Society of Cardiology Consensus Statements on the Diagnosis and Management of Acute MI-Cardiogenic Shock and Endorsed by the Asian Pacific Society of Interventional Cardiology In the Asia-Pacific region, acute coronary syndrome (ACS) remains a major cause of death and disability, with in-hospit...
Source: Radcliffe Cardiology - April 23, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

Optimum Risk Assessment for Stroke in Atrial Fibrillation: Should We Hold the Status Quo or Consider Magnitude Synergism and Left Atrial Appendage Anatomy?
Optimum Risk Assessment for Stroke in Atrial Fibrillation: Should We Hold the Status Quo or Consider Magnitude Synergism and Left Atrial Appendage Anatomy? Thromboembolic stroke and systemic embolism are generally agreed to be the major morbidity/mortality concerns for patients with AF. However, the risk of thromboembolism (TE) is not the same for all AF patients. While ECG rhythm strips of patients with AF are generally indistinguishable, it has long been known that ... Optimum Risk Assessment for Stroke in Atrial Fibrillation: Should We Hold the Status Quo or Consider Magnitude Synergism and Left Atrial Ap...
Source: Radcliffe Cardiology - April 16, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research

A Rare Case of Tuberculous Constrictive Pericarditis Due to Disseminated Tuberculosis with Response to Anti-tuberculosis Chemotherapy and Steroids in a Developed City State
Tuberculosis (TB) is a rare cause of constrictive pericarditis in the developed world, accounting for<5% of all cases.1 In countries where TB is endemic, tuberculous pericarditis is the most common manifestation of TB in the cardiovascular system and pericardial constriction can still occur in up... A Rare Case of Tuberculous Constrictive Pericarditis Due to Disseminated Tuberculosis with Response to Anti-tuberculosis Chemotherapy and Steroids in a Developed City State Tuberculosis (TB) is a rare cause of constrictive pericarditis in the developed world, accounting for<5% of all cases.1 ...
Source: Radcliffe Cardiology - April 10, 2024 Category: Cardiology Authors: dbarot525787 Source Type: research