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Exercise Therapy for Chronic Symptomatic Peripheral Artery Disease: A Clinical Consensus Document of the European Society of Cardiology Working Group on Aorta and Peripheral Vascular Diseases in Collaboration With the European Society of Vascular Medicine and the European Society for Vascular Surgery
All guidelines worldwide strongly recommend exercise as a pillar in the management of patients affected by lower extremity peripheral artery disease (PAD). Exercise therapy in this setting presents different modalities, and a structured programme provides optimal results. This clinical consensus paper is intended to promote and assist the set up of comprehensive exercise programmes and best advice for patients with symptomatic chronic PAD. Different exercise training protocols specific for patients with PAD are presented. (Source: Journal of Vascular Surgery)
Source: Journal of Vascular Surgery - April 18, 2024 Category: Surgery Authors: L. Mazzolai, J. Belch, M. Venermo, V. Aboyans, M. Brodmann, A. Bura-Rivi ère, S. Debus, C. Espinola-Klein, A.E. Harwood, J.A. Hawley, S. Lanzi, J. Madarič, G. Mahé, D. Malatesta, O. Schlager, A. Schmidt-Trucksäss, C. Seenan, H. Sillesen, G.A. Tew, A. Source Type: research

Patient characteristics associated with acute kidney injury following coronary angiography
CONCLUSION: Peripheral artery disease, multivessel disease, and creatinine >1.5 mg/dL were associated with a higher risk of AKI in patients undergoing coronary angiography in this single-center retrospective cohort.PMID:38628321 | PMC:PMC11018084 | DOI:10.1080/08998280.2024.2301903 (Source: Baylor University Medical Center Proceedings)
Source: Baylor University Medical Center Proceedings - April 17, 2024 Category: Universities & Medical Training Authors: Jonathan Knott Michael Engheta Jeffery Michel Timothy Mixon R Jay Widmer Source Type: research

Two-year outcomes of endovascular therapy for femoropopliteal arterial lesions for patients with high bleeding risk
AbstractThe Academic Research Consortium (ARC) recently published a definition of patients at high bleeding risk (HBR) undergoing percutaneous coronary intervention. However, the prevalence of the ARC-HBR criteria in patients undergoing endovascular therapy (EVT) for femoropopliteal arterial lesions has not been thoroughly investigated. The study population comprised 165 patients undergoing initial EVT for femoropopliteal lesions between June 2018 and June 2020. They were divided into two groups according to the ARC-HBR criteria. The primary end point was a composite of all-cause death, Bleeding Academic Research Consortiu...
Source: Cardiovascular Intervention and Therapeutics - April 17, 2024 Category: Cardiology Source Type: research

Short-duration aerobic high-intensity intervals versus moderate exercise training intensity in patients with peripheral artery disease: study protocol for a randomised controlled trial (the Angiof-HIIT Study)
This study aims to compare the effects of 12-week-long supervised walking exercise training (high-intensity interval training (HIIT) vs moderate-intensity exercise (MOD)) in patients with chronic symptomatic PAD. Methods and analysis This study is a monocentric, interventional, non-blinded randomised controlled trial. 60 patients (30 in each group) will be randomly allocated (by using the random permuted blocks) to 12 weeks (three times a week) of HIIT or MOD. For HIIT, exercise sessions will consist of alternating brief high-intensity (≥85% of the peak heart rate (HRpeak)) periods (≤60 s) of work with periods of pa...
Source: BMJ Open - April 17, 2024 Category: General Medicine Authors: Lanzi, S., Pousaz, A., Fresa, M., Besson, C., Desgraz, B., Gremeaux-Bader, V., Mazzolai, L. Tags: Open access, Sports and exercise medicine Source Type: research

Retrospective analysis on diameters of drug-coated balloons and predilatation balloons in infra-inguinal endovascular treatment (RABBIT study)
AbstractThis multicenter retrospective study assessed the clinical outcomes of endovascular therapy (EVT) using a drug-coated balloon (DCB) that was larger than the predilatation balloons for femoropopliteal artery lesions. We analyzed 1140 cases with symptomatic peripheral artery disease that underwent EVT with DCB for femoropopliteal lesions between 2017 and 2021. The primary endpoint was procedural failure, defined as a composite of deteriorated dissection and bailout stenting. The secondary endpoints included deteriorated dissection, bailout stenting, restenosis, and target lesion revascularization. We performed propen...
Source: Cardiovascular Intervention and Therapeutics - April 17, 2024 Category: Cardiology Source Type: research

Impact of a quality improvement initiative on medical management of Veterans with peripheral artery disease
Peripheral artery disease (PAD) is a leading cause of atherosclerotic cardiovascular morbidity and is associated with increased rates of lower extremity amputation (LEA).1 PAD is a strong predictor of both cardiovascular and overall mortality, even more so than prior MI.2,3 In fact, PAD in the absence of known CAD predicted cardiovascular events more strongly than did CAD.4 (Source: The American Journal of Cardiology)
Source: The American Journal of Cardiology - April 16, 2024 Category: Cardiology Authors: Lawrence Hoang, Bidyut Mani, Gina Wilson, Jenifer Chisom Ogu, Subhash Banerjee, Bala Ramanan, J. Gregory Modrall, Carlos H. Timaran, Shirling Tsai Source Type: research

Impact of atrial fibrillation on 1-year outcome in patients with implantable cardioverter defibrillator or cardiac resynchronization therapy with defibrillator: results from the German DEVICE Registry
CONCLUSIONS: Our clinical data on an extended cohort of contemporary patients confirm the significant impact of AF, and its associated comorbidities, upon mortality and major adverse events after implantation of ICD/CRT.PMID:38617758 | PMC:PMC11009579 | DOI:10.21037/jtd-23-274 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Sebastian Feickert Niels Christian Ewertsen Julia K öbe Thomas Kleemann Joachim Jehle Jochen Senges Matthias Hochadel Dietrich Andresen Christoph Stellbrink Lars Eckardt Stefan Spitzer Johannes Brachmann H üseyin Ince Giuseppe D'Ancona Source Type: research

Beyond Venoarterial and Venovenous ECMO: Novel Cannulation Strategies
Extracorporeal Membrane Oxygenation (ECMO) is most commonly used as either lung support or venovenous ECMO (VV-ECMO) or combined heart and lung support or venoarterial ECMO (VA-ECMO). In certain instances such as large body habitus, peripheral vascular disease or poor vascular access, these strategies may not provide sufficient support or are not feasible to deploy. New strategies for ECMO including parallel VV-ECMO circuits for patients with high cardiac output, veno-venopulmonary ECMO, left atrial venoarterial ECMO, and dual lumen cannula access through the left ventricular apical may be helpful in complex circumstances....
Source: Journal of Cardiothoracic and Vascular Anesthesia - April 15, 2024 Category: Anesthesiology Authors: Anthony Calhoun, Christopher Szabo, David Convissar, Dominic V. Pisano, Jamel Ortoleva Tags: Editorial Source Type: research

Risk factors for and risk of all-cause and atherosclerotic cardiovascular disease mortality in people with type 2 diabetes and peripheral artery disease: an observational, register-based cohort study
Type 2 diabetes (T2D) and peripheral artery disease (PAD) are recognized as independent risk factors contributing to excess mortality. Contemporary observational studies exploring the associations of risk fact... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 15, 2024 Category: Cardiology Authors: Tarik Avdic, Hanne K. Carlsen, Aidin Rawshani, Soffia Gudbj örnsdottir, Zacharias Mandalenakis and Björn Eliasson Tags: Research Source Type: research

Cardiovascular risk and inflammation in a population with autoimmune diseases: a narrative review
Front Immunol. 2024 Mar 28;15:1380372. doi: 10.3389/fimmu.2024.1380372. eCollection 2024.ABSTRACTJuvenile Systemic Connective Tissue Diseases (JSCTD) are a heterogeneous group of chronic autoimmune diseases, associated with dyslipidemia and increased cardiovascular risk are related. Studies from the last 10 years, from 2013 to 2022, on lipid profiles in JSCTD were collected. Different studies on lipid profiles in children affected by JSCTD were selected, because the aim is to analyze the cardiovascular risk and the possibility of atherosclerosis in these patients in whom, sometimes, corticosteroid therapies and immunosuppr...
Source: Atherosclerosis - April 12, 2024 Category: Cardiology Authors: Camilla Bertoni Alessandra Mazzocchi Ludovica Leone Carlo Agostoni Giovanni Filocamo Source Type: research

Reversion of the Inflammatory Markers in Patients With Chronic Limb-Threatening Ischemia
CONCLUSIONS: CLTI has an inflammatory environment that can be partially reverted after resolution of the ischemic process, emphasizing the importance of timely intervention.PMID:38606780 | DOI:10.1161/JAHA.123.031922 (Source: Atherosclerosis)
Source: Atherosclerosis - April 12, 2024 Category: Cardiology Authors: Joana Ferreira Susana Roque Alexandre Lima Carneiro Adhemar Longatto-Filho Isabel Vila Cristina Cunha Cristina Silva Am ílcar Mesquita Jorge Cotter Margarida Correia-Neves Armando Mansilha Pedro Guimar ães Cunha Source Type: research

Profiling of differentially expressed MicroRNAs in familial hypercholesterolemia via direct hybridization
CONCLUSIONS: The case-control nature of this study precluded the possibility of assessing the predictive role of the identified differentially expressed miRNAs for cardiovascular events. Therefore, the signature of miRNAs reflecting the pathogenesis of both HeFH and HoFH.PMID:38590435 | PMC:PMC10999490 | DOI:10.1016/j.ncrna.2024.02.017 (Source: Cell Research)
Source: Cell Research - April 9, 2024 Category: Cytology Authors: Erika Cione Maryam Mahjoubin-Tehran Tiziana Bacchetti Maciej Banach Gianna Ferretti Amirhossein Sahebkar Source Type: research

Factors Associated With Physical Inactivity of Recipients of a Kidney Transplant: Results From the ADHERE BRAZIL Multicenter Study
CONCLUSIONS: This study identified factors associated with physical inactivity after kidney transplantation that may guide future multilevel behavioral change interventions for physical activity.IMPACT: In a multicenter sample of recipients of a kidney transplant with a prevalence of physical inactivity of 69%, we found associations between this behavior and patient- and center-level factors. At the patient level, the chance of physical inactivity was positively associated with smoking, obesity, and patient morbidity (peripheral vascular disease and hospitalization events after kidney transplantation). Conversely, a high f...
Source: Health Physics - April 9, 2024 Category: Physics Authors: Emiliana S Sertorio Fernando A B Colugnati Kris Denhaerynck Stefan De Smet Jose O P Medina Maycon M Reboredo Sabina De Geest Helady Sanders-Pinheiro None On Behalf Of The Adhere Brazil Study Team Source Type: research