Assessing vaccine hesitancy and support for vaccination requirements for pets and potential Spillovers from humans
CONCLUSION: The high correlation between pet and human measures raises the stake for public health efforts to improve attitudes about vaccines and vaccination rates across the board. Strong support for vaccination requirements should encourage policymakers to explore policy change. Moreover, veterinarians and their associations should consider expanding the number of core vaccinations.PMID:37935596 | DOI:10.1016/j.vaccine.2023.10.061 (Source: Vaccine)
Source: Vaccine - November 7, 2023 Category: Allergy & Immunology Authors: Simon F Haeder Source Type: research
Assessing vaccine hesitancy and support for vaccination requirements for pets and potential Spillovers from humans
CONCLUSION: The high correlation between pet and human measures raises the stake for public health efforts to improve attitudes about vaccines and vaccination rates across the board. Strong support for vaccination requirements should encourage policymakers to explore policy change. Moreover, veterinarians and their associations should consider expanding the number of core vaccinations.PMID:37935596 | DOI:10.1016/j.vaccine.2023.10.061 (Source: Vaccine)
Source: Vaccine - November 7, 2023 Category: Allergy & Immunology Authors: Simon F Haeder Source Type: research
Protoparvovirus carnivoran 1 infection of golden jackals Canis aureus in Serbia
AbstractParvoviruses are among the major animal pathogens that can cause considerable health disorders ranging from subclinical to lethal in domestic and wild animals. Golden jackal (Canis aureus), an expanding European species, is a reservoir of many pathogens, including vector-borne diseases and zoonoses. Given the importance of parvovirus infections in dogs and cats, this study aimed to unfold the virus prevalence and molecular characterisation in the golden jackal population in Serbia. The spleen samples from 68 hunted jackals during 2022/2023 were tested for the VP2-specific genome region of Protoparvovirus carnivoran...
Source: Veterinary Research Communications - November 7, 2023 Category: Veterinary Research Source Type: research
Five families of diverse DNA viruses comprehensively restructure the nucleus
by Quincy Rosemarie, Bill Sugden
Many viruses have evolved ways to restructure their host cell ’s nucleus profoundly and unexpectedly upon infection. In particular, DNA viruses that need to commandeer their host’s cellular synthetic functions to produce their progeny can induce the condensation and margination of host chromatin during productive infection, a phenomenon known as virus-indu ced reorganization of cellular chromatin (ROCC). These ROCC-inducing DNA viruses belong to 5 families (herpesviruses, baculoviruses, adenoviruses, parvoviruses, and geminiviruses) that infect a wide range of hosts and are important f...
Source: PLoS Biology: Archived Table of Contents - November 6, 2023 Category: Biology Authors: Quincy Rosemarie Source Type: research
Isolation, characterization, and phylogenetic analysis of two new porcine parvovirus 1 isolates from Northern China
In this study, we isolated two new PPV1 (HLJ202108-Y and SDLC202109) from northern China and sequenced their whole genomes. The new isolates were found to have three amino acid substitutions (K195R, K562R, and S578P) in nonstructural protein 1. The VP2 amino acid site contained nine nonsynonymous substitutions, including six substitutions of the Kresse strain corresponding to the NADL-2 strain and three substitutions of A414S, S436T, and N555K. Genetic evolution analysis was conducted on 107 reference sequences available in the GenBank database, and 4-5 PPV1 taxa were defined. The new isolates were in the same phylogenetic...
Source: Virus Research - November 3, 2023 Category: Virology Authors: Huiwei Deng Guangyi Cong Hongfeng Wang Zedong Hu Da Shi Hongyan Shi Changyou Xia Fang Fu Li Feng Source Type: research
Viruses, Vol. 15, Pages 2179: Suitable Disinfectants with Proven Efficacy for Genetically Modified Viruses and Viral Vectors
This article proposes a new activity claim known as “virucidal activity PLUS”, summarizes the available methods for evaluating the virucidal activity of chemical disinfectants against genetically modified organisms (GMOs) using current European standards, including the activity against highly resistant parvoviridae such as the adeno-associated virus (AAV), and provides guidance on the selection of disinfectants for pharmaceutical manufacturers, laboratories, and clinical users. (Source: Viruses)
Source: Viruses - October 30, 2023 Category: Virology Authors: Maren Eggers Ingeborg Schwebke Johannes Bl ümel Franziska Brandt Helmut Fickenscher J ürgen Gebel Nils H übner Janis A. M üller Holger F. Rabenau Ingrid Rapp Sven Reiche Eike Steinmann Jochen Steinmann Paula Zwicker Miranda Suchomel Tags: Review Source Type: research
Evaluation of viral infection as an etiology of ME/CFS: a systematic review and meta-analysis
CONCLUSION: This study comprehensively evaluated the risk of viral infections associated with ME/CFS, and identified BDV. These results provide valuable reference data for future studies investigating the role of viruses in the causation of ME/CFS.PMID:37898798 | DOI:10.1186/s12967-023-04635-0 (Source: Herpes)
Source: Herpes - October 29, 2023 Category: Infectious Diseases Authors: Jae-Hyun Hwang Jin-Seok Lee Hyeon-Muk Oh Eun-Jung Lee Eun-Jin Lim Chang-Gue Son Source Type: research
Detection and genetic evolution analysis of porcine parvovirus type 7 (PPV7) in Fujian Province
This study provides significant insights into the molecular characteristics of PPV7 in Fujian Province and serves as a crucial foundation for further advancements in PPV7 prevention and control strategies.PMID:37866684 | DOI:10.1016/j.meegid.2023.105515 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 22, 2023 Category: Genetics & Stem Cells Authors: Zixin Lyu Xinjie Zhang Shaohua Xue Xiaoyan Yang Jiankui Liu Kewei Fan Ailing Dai Source Type: research
Detection and genetic evolution analysis of porcine parvovirus type 7 (PPV7) in Fujian Province
This study provides significant insights into the molecular characteristics of PPV7 in Fujian Province and serves as a crucial foundation for further advancements in PPV7 prevention and control strategies.PMID:37866684 | DOI:10.1016/j.meegid.2023.105515 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 22, 2023 Category: Genetics & Stem Cells Authors: Zixin Lyu Xinjie Zhang Shaohua Xue Xiaoyan Yang Jiankui Liu Kewei Fan Ailing Dai Source Type: research
Detection and genetic evolution analysis of porcine parvovirus type 7 (PPV7) in Fujian Province
This study provides significant insights into the molecular characteristics of PPV7 in Fujian Province and serves as a crucial foundation for further advancements in PPV7 prevention and control strategies.PMID:37866684 | DOI:10.1016/j.meegid.2023.105515 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 22, 2023 Category: Genetics & Stem Cells Authors: Zixin Lyu Xinjie Zhang Shaohua Xue Xiaoyan Yang Jiankui Liu Kewei Fan Ailing Dai Source Type: research
Viruses, Vol. 15, Pages 2129: The XVIII International Parvovirus Workshop Rimini, Italy, 14 & ndash;17 June 2022
Viruses, Vol. 15, Pages 2129: The XVIII International Parvovirus Workshop Rimini, Italy, 14–17 June 2022
Viruses doi: 10.3390/v15102129
Authors:
Giorgio Gallinella
Antonio Marchini
The XVIII International Parvovirus Workshop took place in Rimini, Italy, from 14 to 17 June 2022 as an on-site event, continuing the series of meetings started in 1985 and continuously held every two years. The communications dealt with all aspects of research in the field, from evolution and structure to receptors, from replication to trafficking, from virus–host interactions to clinical and veterinarian virolo...
Source: Viruses - October 20, 2023 Category: Virology Authors: Giorgio Gallinella Antonio Marchini Tags: Conference Report Source Type: research
Unmapped short reads from whole-genome sequencing indicate potential infectious pathogens in german black Pied cattle
In this study, unmapped reads from 302 German Black Pied cattle were analyzed to identify potential pathogenic DNA. These unmapped reads were assembled and blasted against NCBI ’s database to identify bacterial and viral sequences. The results provided evidence for the presence of pathogens. We found sequences ofBovine parvovirus 3 andMycoplasma species. These findings emphasize the information content of unmapped reads for gaining insight into bacterial and viral infections, which is important for veterinarians and epidemiologists. (Source: Veterinary Research)
Source: Veterinary Research - October 18, 2023 Category: Veterinary Research Source Type: research
Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections
ConclusionPrevious viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease. (Source: Cancer Immunology, Immunotherapy)
Source: Cancer Immunology, Immunotherapy - October 14, 2023 Category: Cancer & Oncology Source Type: research
Virus filtration using small pore virus filter in downstream processing of biotherapeutic products: The effect of operating pressure
Biologicals. 2023 Oct 12;84:101718. doi: 10.1016/j.biologicals.2023.101718. Online ahead of print.ABSTRACTVirus filtration is a robust and effective method to remove potential virus contaminants. Planova 20 N, a virus filter form Asahi Kasei Bioprocess, has been widely used in the manufacturing process of biotherapeutics. Previous studies have shown that parvovirus removal by Planova 20 N can be impacted by low operation pressure and depressurization. Therefore, it is critical to define an operating pressure range for robust virus removal. In this work, the effect of pressure combined with depressurization on virus removal...
Source: Biologicals : Journal of the International Association of Biological Standardization - October 14, 2023 Category: Biotechnology Authors: Na Liu Tiandan Xu Source Type: research
Virus filtration using small pore virus filter in downstream processing of biotherapeutic products: The effect of operating pressure
Biologicals. 2023 Oct 12;84:101718. doi: 10.1016/j.biologicals.2023.101718. Online ahead of print.ABSTRACTVirus filtration is a robust and effective method to remove potential virus contaminants. Planova 20 N, a virus filter form Asahi Kasei Bioprocess, has been widely used in the manufacturing process of biotherapeutics. Previous studies have shown that parvovirus removal by Planova 20 N can be impacted by low operation pressure and depressurization. Therefore, it is critical to define an operating pressure range for robust virus removal. In this work, the effect of pressure combined with depressurization on virus removal...
Source: Biologicals : Journal of the International Association of Biological Standardization - October 14, 2023 Category: Biotechnology Authors: Na Liu Tiandan Xu Source Type: research
