Prevalence of viral agents causing swine reproductive failure in Korea and the development of multiplex real-time PCR and RT-PCR assays
This study aimed to investigate the prevalence of viral agents causing reproductive failure in pigs in Korea. In addition, two types of multiplex real-time PCR (mqPCR) were developed for the simultaneous detection of Aujeszky's disease virus (ADV) and porcine parvovirus (PPV) in mqPCR and encephalomyocarditis virus (EMCV) and Japanese encephalitis virus (JEV) in reverse transcription mqPCR (mRT-qPCR). A total of 150 aborted fetus samples collected from 2020 to 2022 were analyzed. Porcine reproductive and respiratory syndrome virus was the most prevalent (49/150 32.7%), followed by porcine circovirus type 2 (31/150, 20.7%),...
Source: Biologicals : Journal of the International Association of Biological Standardization - April 19, 2024 Category: Biotechnology Authors: Go-Eun Shin Kyoung-Ki Lee Bok-Kyung Ku Su Hong Oh Sang-Ho Jang Bokyu Kang Hye-Young Jeoung Source Type: research
Stability and integrity of self-assembled bovine parvovirus virus ‑like particles (BPV‑VLPs) of VP2 and combination of VP1VP2 assisted by baculovirus-insect cell expression: a potential logistical platform for vaccine deployment
Bovine parvovirus (BPV) is an autonomous DNA virus with a smaller molecular size and subtle differences in its structural proteins, unlike other animal parvoviruses. More importantly, this virus has the potent... (Source: Virology Journal)
Source: Virology Journal - April 19, 2024 Category: Virology Authors: Ashenafi Kiros Wubshet, Guo-xiu Li, Qian Li, Jun-Fei Dai, Yao-Zhong Ding, Luoyi Zhou, Min Qu, Yang Wang, Zhongyuan Ma, Gebremeskel Mamu Werid, Birhanu Hadush Abera, Asmelash Tassew Kebede, Yuefeng Sun, Xiangping Yin, Yongsheng Liu and Zhang Jie Tags: Methodology Source Type: research
Viruses, Vol. 16, Pages 621: Chimeric Porcine Parvovirus VP2 Virus-like Particles with Epitopes of South African Serotype 2 Foot-and-Mouth Disease Virus Elicits Specific Humoral and Cellular Responses in Mice
In this study, chimeric porcine parvovirus VP2 VLPs (chimeric PPV-SAT2-VLPs) expressing the T-and/or B-cell epitopes of the structural protein VP1 of FMDV SAT2 were produced using the recombinant pFastBac™ Dual vector of baculoviruses in Sf9 and HF cells We used the Bac-to-Bac system to construct the recombinant baculoviruses. The VP2-VLP--SAT2 chimeras displayed chimeric T-cell epitope (amino acids 21–40 of VP1) and/or the B-cell epitope (amino acids 135–174) of SAT FMDV VP1 by substitution of the corresponding regions at the N terminus (amino acids 2–23) and/or loop...
Source: Viruses - April 17, 2024 Category: Virology Authors: Qian Li Xusheng Ma Yaner Shen Junfei Dai Xiaofeng Nian Xiaofen Shang Jiao Chen Ashenafi Kiros Wubshet Jie Zhang Haixue Zheng Tags: Article Source Type: research
A Multiplex Fluorescence of Loop Primer Upon Self-Dequenching Loop-Mediated Isothermal Amplification Assay for the Detection of Epstein –Barr Virus and Human Parvovirus B19 in Clinical Transplant Samples
Viral Immunology, Ahead of Print. (Source: Viral Immunology)
Source: Viral Immunology - April 16, 2024 Category: Allergy & Immunology Authors: Yushan Xu Miaomiao Li Mengjiao Lin Yan Lv Dawei Cui Yongjun Wang Jue Xie Source Type: research
Heritability and genome-wide association study of vaccine-induced immune response in Beagles: A pilot study
The objective of this study was to estimate the heritability of the antibody response to vaccination against viral and bacterial pathogens, and to identify genes driving variation of the immune response to vaccination in Beagles. Sixty puppies were immunized following a standard vaccination schedule with an attenuated combination vaccine containing antigens for canine adenovirus type 2, canine distemper virus, canine parainfluenza virus, canine parvovirus, and four strains of Leptospira bacteria. Serum antibody measurements for each viral and bacterial component were measured at multiple time points. Heritability estimatio...
Source: Vaccine - April 11, 2024 Category: Allergy & Immunology Authors: Jeanna M Blake James Thompson Harm HogenEsch Kari J Ekenstedt Source Type: research
Heritability and genome-wide association study of vaccine-induced immune response in Beagles: A pilot study
The objective of this study was to estimate the heritability of the antibody response to vaccination against viral and bacterial pathogens, and to identify genes driving variation of the immune response to vaccination in Beagles. Sixty puppies were immunized following a standard vaccination schedule with an attenuated combination vaccine containing antigens for canine adenovirus type 2, canine distemper virus, canine parainfluenza virus, canine parvovirus, and four strains of Leptospira bacteria. Serum antibody measurements for each viral and bacterial component were measured at multiple time points. Heritability estimatio...
Source: Vaccine - April 11, 2024 Category: Allergy & Immunology Authors: Jeanna M Blake James Thompson Harm HogenEsch Kari J Ekenstedt Source Type: research
Opportunistic sampling of yellow canary (Crithagra flaviventris) has revealed a high genetic diversity of detected parvoviral sequences
Virology. 2024 Apr 4;595:110081. doi: 10.1016/j.virol.2024.110081. Online ahead of print.ABSTRACTParvoviruses are known to be significant viral pathogens that infect a wide range of species globally. However, little is known about the parvoviruses circulating in Australian birds, including yellow canaries. Here, we present four parvoviral sequences including three novel parvoviruses detected from 10 yellow canaries (Crithagra flaviventris), named canary chaphamaparvovirus 1 and -2 (CaChPV1 and CaChPV2), canary dependoparvovirus 1 and -2 (CaDePV1 and CaDePV2). The whole genome sequences of CaChPV1, CaChPV2, CaDePV1, and CaD...
Source: Virology - April 10, 2024 Category: Virology Authors: Yuhao Zhang Saranika Talukder Md Safiul Alam Bhuiyan Lei He Subir Sarker Source Type: research
Opportunistic sampling of yellow canary (Crithagra flaviventris) has revealed a high genetic diversity of detected parvoviral sequences
Virology. 2024 Apr 4;595:110081. doi: 10.1016/j.virol.2024.110081. Online ahead of print.ABSTRACTParvoviruses are known to be significant viral pathogens that infect a wide range of species globally. However, little is known about the parvoviruses circulating in Australian birds, including yellow canaries. Here, we present four parvoviral sequences including three novel parvoviruses detected from 10 yellow canaries (Crithagra flaviventris), named canary chaphamaparvovirus 1 and -2 (CaChPV1 and CaChPV2), canary dependoparvovirus 1 and -2 (CaDePV1 and CaDePV2). The whole genome sequences of CaChPV1, CaChPV2, CaDePV1, and CaD...
Source: Virology - April 10, 2024 Category: Virology Authors: Yuhao Zhang Saranika Talukder Md Safiul Alam Bhuiyan Lei He Subir Sarker Source Type: research
Opportunistic sampling of yellow canary (Crithagra flaviventris) has revealed a high genetic diversity of detected parvoviral sequences
Virology. 2024 Apr 4;595:110081. doi: 10.1016/j.virol.2024.110081. Online ahead of print.ABSTRACTParvoviruses are known to be significant viral pathogens that infect a wide range of species globally. However, little is known about the parvoviruses circulating in Australian birds, including yellow canaries. Here, we present four parvoviral sequences including three novel parvoviruses detected from 10 yellow canaries (Crithagra flaviventris), named canary chaphamaparvovirus 1 and -2 (CaChPV1 and CaChPV2), canary dependoparvovirus 1 and -2 (CaDePV1 and CaDePV2). The whole genome sequences of CaChPV1, CaChPV2, CaDePV1, and CaD...
Source: Virology - April 10, 2024 Category: Virology Authors: Yuhao Zhang Saranika Talukder Md Safiul Alam Bhuiyan Lei He Subir Sarker Source Type: research
Opportunistic sampling of yellow canary (Crithagra flaviventris) has revealed a high genetic diversity of detected parvoviral sequences
Virology. 2024 Apr 4;595:110081. doi: 10.1016/j.virol.2024.110081. Online ahead of print.ABSTRACTParvoviruses are known to be significant viral pathogens that infect a wide range of species globally. However, little is known about the parvoviruses circulating in Australian birds, including yellow canaries. Here, we present four parvoviral sequences including three novel parvoviruses detected from 10 yellow canaries (Crithagra flaviventris), named canary chaphamaparvovirus 1 and -2 (CaChPV1 and CaChPV2), canary dependoparvovirus 1 and -2 (CaDePV1 and CaDePV2). The whole genome sequences of CaChPV1, CaChPV2, CaDePV1, and CaD...
Source: Virology - April 10, 2024 Category: Virology Authors: Yuhao Zhang Saranika Talukder Md Safiul Alam Bhuiyan Lei He Subir Sarker Source Type: research
Opportunistic sampling of yellow canary (Crithagra flaviventris) has revealed a high genetic diversity of detected parvoviral sequences
Virology. 2024 Apr 4;595:110081. doi: 10.1016/j.virol.2024.110081. Online ahead of print.ABSTRACTParvoviruses are known to be significant viral pathogens that infect a wide range of species globally. However, little is known about the parvoviruses circulating in Australian birds, including yellow canaries. Here, we present four parvoviral sequences including three novel parvoviruses detected from 10 yellow canaries (Crithagra flaviventris), named canary chaphamaparvovirus 1 and -2 (CaChPV1 and CaChPV2), canary dependoparvovirus 1 and -2 (CaDePV1 and CaDePV2). The whole genome sequences of CaChPV1, CaChPV2, CaDePV1, and CaD...
Source: Virology - April 10, 2024 Category: Virology Authors: Yuhao Zhang Saranika Talukder Md Safiul Alam Bhuiyan Lei He Subir Sarker Source Type: research
Opportunistic sampling of yellow canary (Crithagra flaviventris) has revealed a high genetic diversity of detected parvoviral sequences
Virology. 2024 Apr 4;595:110081. doi: 10.1016/j.virol.2024.110081. Online ahead of print.ABSTRACTParvoviruses are known to be significant viral pathogens that infect a wide range of species globally. However, little is known about the parvoviruses circulating in Australian birds, including yellow canaries. Here, we present four parvoviral sequences including three novel parvoviruses detected from 10 yellow canaries (Crithagra flaviventris), named canary chaphamaparvovirus 1 and -2 (CaChPV1 and CaChPV2), canary dependoparvovirus 1 and -2 (CaDePV1 and CaDePV2). The whole genome sequences of CaChPV1, CaChPV2, CaDePV1, and CaD...
Source: Virology - April 10, 2024 Category: Virology Authors: Yuhao Zhang Saranika Talukder Md Safiul Alam Bhuiyan Lei He Subir Sarker Source Type: research
Congenital Infectious Encephalopathies from the Intrapartum Period to Postnatal Life
Congenital infections are a common but often underrecognized cause of fetal brain abnormalities, as well as fetal-neonatal morbidity and mortality, that should be considered by all healthcare professionals providing neurological care to fetuses and newborns.Maternal infection with various pathogens (cytomegalovirus, Toxoplasmosis, Rubella virus, Parvovirus B19, lymphocytic choriomeningitis virus, syphilis, Zika virus, varicella zoster virus) during pregnancy can be transmitted to the developing fetus, which can cause multisystem dysfunction and destructive or malformative central nervous system lesions, which can be recogn...
Source: Seminars in Fetal and Neonatal Medicine - April 10, 2024 Category: Perinatology & Neonatology Authors: Olivier Fortin, Roberta L. DeBiasi, Sarah B. Mulkey Source Type: research
TCR αβ-depleted hematopoietic stem cell transplant and third-party CD45RA+ depleted adoptive cell therapy for treatment of post-transplant parvovirus B19 aplastic crisis
CD19 and CD22-targeted chimeric antigen receptor (CAR) T-cell therapy bridged to hematopoietic stem cell transplantation (HSCT) has emerged as an effective therapeutic approach for refractory/relapsed acute lymphoblastic leukemia [1,2]. However, despite successful therapy, patients remain vulnerable to viral infections caused by prolonged immune system deficiency. Human parvovirus (HPV) B19 infection is among the frequently encountered viral infections post-transplantation. Effective treatment for persistent HPV B19 infection in immunocompromised patients has yet to be established. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - April 5, 2024 Category: Infectious Diseases Authors: Manpin Zhang, Chengjuan Luo, Jianmin Wang, Hua Zhu, Changying Luo, Xia Qin, Xiaohang Huang, Yuchen Lin, Jing Chen Tags: Case Report Source Type: research
Detection and genetic characterization of circulating canine parvovirus from stray dogs in Shanghai, China
This study further confirmed the prevalence of CPV-2c and new-CPV-2b in Shanghai, and also found a new mutation site of new-CPV-2c, which provided a theoretical basis for further enriching the epidemiological data of CPV-2 in Shanghai, as well as the development of vaccines and the prevention and control of the disease.PMID:38555807 | DOI:10.1016/j.virol.2024.110041 (Source: Virology)
Source: Virology - March 31, 2024 Category: Virology Authors: Junyi Pu Yan Zhang Dengke Zhong Qiusheng Chen Source Type: research
