Parvovirus Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Development of a Large-Scale Pathogen Screening Test for the Biosafety Evaluation of Canine Mesenchymal Stem Cells
CONCLUSION: In this study, we established and validated reliable, highly sensitive, and accurate nucleic acid-based testing methods for a broad spectrum of canine pathogens.PMID:38097939 | PMC:PMC10720183 | DOI:10.1186/s12575-023-00226-x (Source: Biological Procedures Online)
Source: Biological Procedures Online - December 15, 2023 Category: Molecular Biology Authors: Emese Pekker Katalin Priskin Éva Szabó-Kriston Bernadett Cs ányi Orsolya Buz ás-Bereczki Lili Adorj án Val éria Szukacsov Lajos Pint ér Mikl ós Rusvai Paul Cooper Endre Kiss-T óth Lajos Haracska Source Type: research

Genetic diversity and relatedness of feline parvovirus in Vietnam and its potential implications for canine-feline transmission
In this study, 19 rectal swab samples were collected from northern Vietnam in 2018 –2019 and screened for the presence of FPV using PCR. Through sequence analysis of the full-length VP2 gene, it was found that the FPV strains detected in Vietnam were closely related to those obtained from dogs in Vietnam, Asia, Europe, and America. Moreover, the FPV strains found in Vietnam may constitute a distinct group, related to viruses sampled in China. Interestingly, most of the nucleotide changes identified were T-C substitutions. (Source: Archives of Virology)
Source: Archives of Virology - December 15, 2023 Category: Virology Source Type: research

Development of an accurate and rapid method for whole genome characterization of canine parvovirus
J Virol Methods. 2023 Dec 10:114870. doi: 10.1016/j.jviromet.2023.114870. Online ahead of print.ABSTRACTCanine parvovirus is a highly contagious pathogen affecting domestic dogs and other carnivores globally. Monitoring CPV through continuous genomic surveillance is crucial for mapping variability and developing effective control measures. Here, we developed a method using multiplex-PCR-next-generation sequencing to obtain full-length CPV genomes directly from clinical samples. This approach utilizes tiling and tailed amplicons to amplify overlapping fragments of roughly 250 base pairs. This enables the creation of Illumin...
Source: Journal of Virological Methods - December 12, 2023 Category: Virology Authors: Emma Condon Sof ía Grecco Ana Marandino Jaime Aldaz Javier Enciso Luis Alfaro Danilo Bucafusco Ruben P érez Yanina Panzera Source Type: research

Viruses, Vol. 15, Pages 2398: The Novel Porcine Parvoviruses: Current State of Knowledge and Their Possible Implications in Clinical Syndromes in Pigs
o Jaime Parvoviruses (PVs) affect various animal species causing different diseases. To date, eight different porcine parvoviruses (PPV1 through PPV8) are recognized in the swine population, all of which are distributed among subfamilies and genera of the Parvoviridae family. PPV1 is the oldest and is recognized as the primary agent of SMEDI, while the rest of the PPVs (PPV2 through PPV8) are called novel PPVs (nPPVs). The pathogenesis of nPPVs is still undefined, and whether these viruses are putative disease agents is unknown. Structurally, the PPVs are very similar; the differences occur mainly at the level of their...
Source: Viruses - December 9, 2023 Category: Virology Authors: Diana S. Vargas-Bermudez Jose Dario Mogollon Camila Franco-Rodriguez Jairo Jaime Tags: Review Source Type: research

Molecular typing of canine parvovirus type 2 by VP2 gene sequencing and restriction fragment length polymorphism in affected dogs from Egypt
This study reports the prevalence and molecular analysis of CPV-2 variants collected from El-Gharbia and Kafrelsheikh governorates in the Delta of Egypt.MethodsIn this study, 320 rectal swabs were collected from infected domestic dogs from two districts in delta Egypt. The samples were investigated by rapid immunochromatographic test and polymerase chain reaction for detection the prevalence of CPV-2 variants. The genetic characterization was performed using restriction fragment length polymorphism (RFLP) analysis and partial VP2 gene sequence.Results and discussionThe viral antigen was detected in (264/320, 82.5%) of samp...
Source: Frontiers in Microbiology - December 7, 2023 Category: Microbiology Source Type: research

Structural Shifts of the Parvovirus B19 Capsid Receptor-binding Domain: A Peptide Study
CONCLUSION: Loss of function Y20W substitution in VP1 capsid protein prevents the shift into the beta-structural state by way of alpha helix stabilization and the decrease of its ability to turn into the disordered state.PMID:38053353 | DOI:10.2174/0109298665272845231121064717 (Source: Protein and Peptide Letters)
Source: Protein and Peptide Letters - December 6, 2023 Category: Biochemistry Authors: Vladislav Victorovich Khrustalev Aleksander Nicolaevich Stojarov Anastasia Aleksandrovna Akunevich Oleg Evgenyevich Baranov Anna Vladimirovna Popinako Elena Olegovna Samoylovich Marina Anatolyevna Yermolovich Galina Valeryevna Semeiko Egor Gennadyevich Sa Source Type: research

Hemolytic anemia in a two-year-old child: A case of multiple red blood cell abnormalities
Ann Biol Clin (Paris). 2023 Nov 29;81(5). doi: 10.1684/abc.2023.1843. Online ahead of print.ABSTRACTThe discovery of hemolytic anemia requires a meticulous investigation to determine its etiology. Among patients of African origin, it is not uncommon to find multiple constitutional red blood cell abnormalities, which can complicate diagnosis. We herein describe the case of a two-year-old child presenting with acute hemolytic anemia. A G6PD deficiency, hereditary spherocytosis, and a sickle cell trait A/S were simultaneously identified, all within the context of a primary infection with Parvovirus B19. This virus commonly tr...
Source: Annales de Biologie Clinique - November 29, 2023 Category: Biochemistry Authors: Romain Ravel-Chapuis L éo Mottin Ma ïssa Souissi Agn ès Lahary Victor Bob ée Source Type: research