Immune checkpoint inhibitor-induced neurotoxicity is not associated with seroprevalence of neurotropic infections

ConclusionPrevious viral, bacterial and protozoal neurotropic infections appear not to be associated with the development of neurological irAEs in melanoma patients who underwent therapy with ICI across 3 countries. Further efforts are needed to unravel the factors underlying neurological irAEs in order to identify risk factors for these toxicities, especially with the increasing use of ICI in earlier stage disease.
Source: Cancer Immunology, Immunotherapy - Category: Cancer & Oncology Source Type: research