What Are the Symptoms of Herpes Simplex Keratitis?
Discussion Herpes simplex virus (HSV) infections are common with an estimated 50% of the US population being infected by age 30, and with latent infection harboring in the trigeminal nerve in 100% of people by age 60 years. HSV infections can cause a vesicular or pustular skin rash that is painful, burning or pruritic and also flu-like symptoms with fever, chills, headache, and fatigue. HSV can also be asymptomatic. To laymen, herpes simplex viruses cause “cold sores,” but to health care personnel, herpes causes many systemic infections including eczema herpeticum, folliculitis, herpes gladiatorum, whitlow, e...
Source: PediatricEducation.org - October 5, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

What Are Systemic Disease Causes of Oral Ulcers?
Discussion Oral ulcers are common problems seen by dentists but pediatricians also see them. Usually families have are concerned because they are painful and acute. Ulcers are sometime noticed by the physician and not the family as in the case of herpangina or hand-foot and mouth disease. Chronic or recurrent ulcerations present less commonly and therefore it may be more difficult to determine their etiology. Many of the systemic disease causes of oral ulcers are overall infrequent and/or not common in the pediatric age range. Ulcers can be classified in several ways but acute ulcers are usually painful and last less tha...
Source: PediatricEducation.org - September 21, 2020 Category: Pediatrics Authors: Pediatric Education Tags: Uncategorized Source Type: news

Are Cold Sores and Canker Sores the Same Thing?
Title: Are Cold Sores and Canker Sores the Same Thing?Category: Diseases and ConditionsCreated: 9/18/2020 12:00:00 AMLast Editorial Review: 9/18/2020 12:00:00 AM (Source: MedicineNet Skin General)
Source: MedicineNet Skin General - September 18, 2020 Category: Dermatology Source Type: news

Researchers identify key role of immune cells in brain infection
(University of Liverpool) Researchers at the University of Liverpool have identified the specific type of immune cell that induces brain inflammation in herpes simplex virus (HSV) encephalitis. Crucially, they have also determined the signalling protein that calls this immune cell into the brain from the bloodstream. The findings, published in Cell Reports, could aid the development of targeted treatments for the brain infection, which is the most common cause of viral encephalitis worldwide. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - September 15, 2020 Category: International Medicine & Public Health Source Type: news

Scientists Use Gene Therapy to Tackle Oral Herpes in Mice
MONDAY, Aug. 31, 2020 -- Gene therapy has nearly eliminated the oral herpes virus in lab animals, researchers report. Using a gene editing technique, they achieved at least a 90% reduction in latent herpes simplex virus 1 (HSV-1) in mice, which... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - August 31, 2020 Category: General Medicine Source Type: news

New gene therapy approach eliminates at least 90% latent herpes simplex virus 1
(Fred Hutchinson Cancer Research Center) Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes. In animal models, the findings show at least a 90 percent decrease in the latent virus, enough researchers expect that it will keep the infection from coming back. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - August 18, 2020 Category: Infectious Diseases Source Type: news

Epidemiology of Herpes Simplex Virus in Europe Transitioning
WEDNESDAY, July 22, 2020 -- The epidemiology of herpes simplex virus (HSV)-1 is transitioning away from oral acquisition in childhood with an increasing proportion of HSV-1 detection in genital herpes, according to a study published online July 16... (Source: Drugs.com - Pharma News)
Source: Drugs.com - Pharma News - July 22, 2020 Category: Pharmaceuticals Source Type: news

TREMFYA ® (guselkumab) Approved by U.S. Food and Drug Administration as the First Selective Interleukin (IL)-23 Inhibitor for Active Psoriatic Arthritis
HORSHAM, PA, July 14, 2020 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has approved TREMFYA® (guselkumab) for adult patients with active psoriatic arthritis (PsA), a chronic progressive disease characterized by painful joints and skin inflammation.[1],[2] TREMFYA is the first treatment approved for active PsA that selectively inhibits interleukin (IL)-23, a naturally occurring cytokine that is involved in normal inflammatory and immune responses associated with the symptoms of PsA. The safety and efficacy of TREMFYA in PsA have b...
Source: Johnson and Johnson - July 14, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

Brain model links herpes virus to development of Alzheimer's disease
Bio-engineered models of the human brain infected with herpes simplex virus-1 develop many of the same characteristics found in Alzheimer's disease, according to a new analysis published by Science Advances. (Source: Health News - UPI.com)
Source: Health News - UPI.com - May 7, 2020 Category: Consumer Health News Source Type: news

Herpes Virus Yields Up Genetic Secrets
WEDNESDAY, April 29, 2020 -- Herpes simplex virus -- the virus that causes cold sores -- is more complex than scientists had thought, a new study finds. It had been believed that there were about 80 so-called open reading frames in the herpes gene,... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - April 29, 2020 Category: General Medicine Source Type: news

Herpes virus decoded
(University of W ü rzburg) The genome of the herpes simplex virus 1 was decoded using new methods. Hundreds of previously unknown gene products were found. The virus causes lip herpes, but can also be life-threatening. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 27, 2020 Category: Infectious Diseases Source Type: news

Roche receives FDA approval for cobas HPV test for use on the cobas 6800/8800 Systems to identify women at risk for cervical cancer
             Basel, 21 April 2020 - Roche (SIX: RO, ROG; OTCQX:RHHBY) today announced US Food and Drug Administration (FDA) approval for the cobas ® HPV test for use on the fully automated, high-throughput cobas® 6800/8800 Systems. The cobas® HPV test identifies women at risk for cervical cancer by detecting the presence of high-risk human papillomavirus (HPV) DNA in cervical samples. Persistent high-risk HPV infections can develop into pre cancerous lesions and, if left untreated, these lesions can progress to cervical cancer.“The approval ...
Source: Roche Media News - April 21, 2020 Category: Pharmaceuticals Source Type: news

Can Vitamin Supplements Prevent Infection? Dr. Mallika Marshall Answers Your Coronavirus Questions
BOSTON (CBS) – As the number of coronavirus cases continues to grow, we are receiving a number of questions from the public. Dr. Mallika Marshall answered some of the questions sent to WBZ-TV’s Facebook, Instagram and Twitter accounts. I am a recovering cancer patient. Would cancer be considered an underlying condition? – Harry, Hingham It depends on the type of cancer and where you are in your recovery. But in general, people with cancer are often treated with medications that can weaken their immune system, putting them at greater risk for infection, including the coronavirus. So I would be particu...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - April 20, 2020 Category: Consumer Health News Authors: Health – CBS Boston Tags: Boston News Health Syndicated Local Coronavirus Dr. Mallika Marshall Source Type: news

Unique new antiviral treatment made using sugar
(University of Manchester) New antiviral materials made from sugar have been developed to destroy viruses on contact and may help in the fight against viral outbreaks. This new development from a collaborative team of international scientists shows promise for the treatment of herpes simplex (cold sore virus), respiratory syncytial virus, hepatitis C, HIV, and Zika virus to name a few. The team have demonstrated success treating a range of viruses in the lab - including respiratory infections to genital herpes. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 29, 2020 Category: Infectious Diseases Source Type: news

Herpes simplex viruses: new relationships between epidemiology and history
(Molecular Biology and Evolution (Oxford University Press)) An Italian research team has refined the history and origins of two extremely common pathogens in human populations, herpes simplex virus type 1 and type 2. Using and applying rather precise data methods they estimated that the circulating strains of herpes simplex virus type 1 migrated from Africa about 5000 years ago. The exit from Africa of herpes simplex virus type 2 was even more recent and probably occurred in the eighteenth century, during the height of the slave trade. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 13, 2020 Category: Infectious Diseases Source Type: news

Herpes's Achilles heel
(Harvard Medical School) Scientists have used the gene-editing tool CRISPR-Cas9 to disrupt both latent reservoirs of the herpes simplex virus and actively replicating virus in human fibroblast cells. Experiments pinpoint weak spot that can make the virus susceptible to gene editing. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - December 12, 2019 Category: Infectious Diseases Source Type: news

Could a hot 'lipstick' end the misery of cold sores?
A German-engineered device, which is the size and shape of a lipstick, may help those infected with the HSV-1 virus, which causes cold sores. (Source: the Mail online | Health)
Source: the Mail online | Health - December 10, 2019 Category: Consumer Health News Source Type: news

Medical News Today: How dormant herpes springs back to life
Researchers have now uncovered a cellular mechanism that may explain how the herpes simplex virus goes into and comes out of hiding. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 23, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Congenital viral infections in England over five decades: a population-based observational study
Study (data from 1968 to 2016) reports that compared with earlier years of the study, rates in 2016 were higher for congenital cytomegalovirus (CMV), herpes simplex virus, and varicella zoster virus, but lower for rubella. (Source: Current Awareness Service for Health (CASH))
Source: Current Awareness Service for Health (CASH) - November 20, 2019 Category: Consumer Health News Source Type: news

Medical News Today: Preventing herpes infections: Study offers new insights
A new study reveals a key protein that can encourage or slow the progression of the herpes simplex virus 1 and tests a compound that blocks the virus. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - October 29, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

What happens when herpes viruses merge? For one, a supervirus
(Natural News) Experts have known that the herpes simplex viruses (HSV) responsible for oral and genital infections were capable of mixing their genetic material. But a recent study by the University of Washington (UW) warns that these pathogens recombine more often than predicted. The HSV-1 virus is classically responsible for oral herpes. Meanwhile, HSV-2 triggers genital herpes. They... (Source: NaturalNews.com)
Source: NaturalNews.com - October 24, 2019 Category: Consumer Health News Source Type: news

Health Tip: Living With Herpes
-- Herpes is a common and usually mild skin condition caused by the herpes simplex virus (HSV). If you are living with herpes, Sutter Health encourages you to: Be alert to triggers that activate herpes. Use safe sex methods, such as... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 7, 2019 Category: General Medicine Source Type: news

Experimental Genital Herpes Vaccine Shows Promise in Mice
THURSDAY, Sept. 26, 2019 -- An experimental vaccine against genital herpes is extremely effective in mice, offering hope of human protection against an incurable sexually transmitted disease. The vaccine prevented transmission of the herpes simplex... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - September 26, 2019 Category: General Medicine Source Type: news

Medical News Today: How long are cold sores contagious for?
Cold sores are highly infectious blisters that develop on the lips and around the mouth. They result from a common viral infection and tend to be contagious for around 15 days. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - September 16, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

These effective natural remedies can help heal cold sores
(Natural News) Cold sores can be painful and inconvenient. If you want relief from these tiny, annoying blisters, try natural remedies like essential oils, L-lysine, or zinc-based creams. What causes cold sores? Cold sores (also known as fever blisters) can appear when you’re sick, stressed, or menstruating. Dr. William Cole, a functional medicine expert, says that cold sores... (Source: NaturalNews.com)
Source: NaturalNews.com - August 15, 2019 Category: Consumer Health News Source Type: news

Mother reveals her baby girl was left unable to eat or drink 'after catching herpes from a kiss'
Katie Taylor, from Sunderland, revealed her daughter developed cold sores around her mouth and she feared the then 10-month-old would develop a serious and deadly infection. (Source: the Mail online | Health)
Source: the Mail online | Health - August 8, 2019 Category: Consumer Health News Source Type: news

Mother's warning after her three-year-old catches the herpes virus after being kissed by a relative
Hayley Etheridge, 24, of Prestwich, was told her son, Baylie-Grey, had the herpes simplex virus. Doctors told Ms Etheridge her unborn baby was at risk if she too had the virus. (Source: the Mail online | Health)
Source: the Mail online | Health - July 31, 2019 Category: Consumer Health News Source Type: news

Squarex Appoints Biopharmaceutical Industry Veteran Jack V. Talley as Chief Executive Officer
ST. PAUL, Minn., July 1, 2019 -- (Healthcare Sales & Marketing Network) -- Squarex, a clinical-stage pharmaceutical company developing a topical immunomodulator for the long-term prevention of recurrent cold sores and other diseases, today announced the a... Biopharmaceuticals, Personnel Squarex, squaric acid dibutyl ester, Herpes Simplex, herpes simplex (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 1, 2019 Category: Pharmaceuticals Source Type: news

What Infectious Diseases are Important to Consider in Transplantation Patients?
Discussion Transplantation is not a common problem for primary care physicians but when a child’s disease has progressed to end-stage organ failure, transplantation can be the only treatment available. While the primary care provider usually is not involved in the daily management of patients before, during and after transplantation, they can be involved in many areas. These can include providing appropriate primary and acute care, ordering and obtaining necessary medical tests, medications and equipment, assisting with medical insurance, providing medical history and records to consultants, translating medical infor...
Source: PediatricEducation.org - June 24, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

DR ELLIE CANNON: How do I get rid of nose blisters? 
The Mail on Sunday's GP discusses cold sores, blisters, pap smear tests, constipation and how forest bathing can help treat mental health problems. (Source: the Mail online | Health)
Source: the Mail online | Health - June 8, 2019 Category: Consumer Health News Source Type: news

What Causes Facial Nerve Palsy?
Discussion Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Honey is 'just as effective as treating cold sores as anti-viral creams'
The trial of 952 participants was led by researchers at the Medical Research Institute of New Zealand (MRINZ). The volunteers used either an anti-viral cream or honey. (Source: the Mail online | Health)
Source: the Mail online | Health - May 27, 2019 Category: Consumer Health News Source Type: news

HSV Strains Recombining, Potentially Impacting Vaccine Development HSV Strains Recombining, Potentially Impacting Vaccine Development
Herpes simplex viruses 1 and 2 (HSV-1 and HSV-2) are recombining, suggesting that live attenuated HSV-2 vaccine candidates carry a"significant risk" of recombining with circulating HSV-1 strains to form an infectious virus, researchers say.Reuters Health Information (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - May 13, 2019 Category: Consumer Health News Tags: Medscape Today News Source Type: news

Simple remedies for herpes you can make at home
(Natural News) Oral herpes is a condition that causes painful cold sores to form on your mouth or face. If you have oral herpes, natural remedies like aloe vera or sage can help relieve your symptoms. What is oral herpes? The herpes simplex virus (HSV) is an infection that causes herpes. Herpes can appear in various... (Source: NaturalNews.com)
Source: NaturalNews.com - May 9, 2019 Category: Consumer Health News Source Type: news

How to manage infected eczema
Red, itchy and inflamed skin is a well-known symptom of what's generally called eczema. While there are a variety of conditions described in this way, the most common type of eczema is atopic dermatitis. Occasionally, complications develop and the skin becomes infected. When this happens, there are a number of treatment options available. Consult your doctor or medical practitioner if you have any questions regarding your eczema treatment plan, but in the meantime, here are some things you'll want to know about the condition. When eczema becomes infected, there are a variety of treatments.  What causes an ec...
Source: Advanced Tissue - May 7, 2019 Category: Dermatology Authors: AdvancedTissue Tags: Wound Care Wound Infection Source Type: news

Water pandemic: Airborne viruses found to survive for weeks in WATER… and most water filters can't remove viruses
(Natural News) It has long been believed that enveloped viruses – viruses like Herpes simplex, chickenpox and the flu virus, which have an outer membranous envelope – are not very stable, and are only infectious through direct and speedy aerosol transmission. A new study by scientists from the Leibniz Institute for Zoo and Wildlife Research... (Source: NaturalNews.com)
Source: NaturalNews.com - May 1, 2019 Category: Consumer Health News Source Type: news

Lines blurring between human herpes simplex viruses
(University of Washington Health Sciences/UW Medicine) The herpes simplex virus (HSV-1) that commonly infects the mouth, is continuing to mix with the genital herpes virus (HSV-2) to create new, different recombinant versions. Genital co-infection with both viruses could create opportunities for the viruses to recombine. This ability of the viruses to recombine poses problems for vaccine development, due to the risk of a live vaccine for genital herpes mixing with HSV-1 to form an infectious recombinant. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - April 30, 2019 Category: Infectious Diseases Source Type: news

Medical News Today: What does herpes look like?
This article discusses what herpes looks like, describes the symptoms, and provides pictures to help identify herpes. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 30, 2019 Category: Consumer Health News Tags: Sexual Health / STDs Source Type: news

Space travel is giving astronauts SHINGLES and cold sores
NASA-funded researchers in the US studied 87 astronauts who had been on space shuttles or the International Space Station and found more than half started shedding previously inactive viruses. (Source: the Mail online | Health)
Source: the Mail online | Health - March 18, 2019 Category: Consumer Health News Source Type: news

Medical News Today: What causes recurrent cold sores?
Many people have cold sores throughout their lives, but some factors can make it easier for them to recur. Learn about why cold sores recur here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 14, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Medical News Today: Lysine for cold sores: Does it work?
Lysine is an amino acid that may help prevent cold sores. Most people get lysine from their diet. In this article, Learn more about whether it is effective and how to use it. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 13, 2019 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Health Tip: Cold Sores 101
-- Cold sores are caused by herpes simplex virus (HSV), a contagious germ. Although some people show no symptoms, others develop unpleasant sores on the mouth or lips. Normally, cold sores will go away on their own within a few weeks. Antiviral... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - March 13, 2019 Category: General Medicine Source Type: news

Sexually transmitted infections are on the rise. Here ’s what you need to know to protect yourself
UCLA Health Rates of sexually transmitted diseases have risen for the past four years to record highs in the United States, according to the Centers for Disease Control and Prevention ’slatest analysis. In California, the state health departmentfound that the number of people diagnosed with syphilis, gonorrhea or chlamydia in 2017 was 45 percent higher than five years prior.These sorts of statistics may spark a fear that there ’s little we can do to protect ourselves — but that’s not the full story.Dr. Leena Nathan, an obstetrician/gynecologist at UCLA Health-Westlake Village, consults with peo...
Source: UCLA Newsroom: Health Sciences - February 14, 2019 Category: Universities & Medical Training Source Type: news

Mayo Clinic Q and A: Cold sore virus can 'wake up' after remaining dormant for years
DEAR MAYO CLINIC:?I have had a few cold sore flare-ups over the past few months after years without getting any. What causes them to come back, and what's the best way to treat them? ANSWER:?Cold sores?are caused by the herpes simplex virus. Once you're exposed to the virus, which is typically passed from skin-to-skin contact, [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - February 8, 2019 Category: Databases & Libraries Source Type: news

Consumer Health: Treating cold sores
Treating cold sores Cold sores, also called fever blisters, are a common viral infection. They are tiny, fluid-filled blisters on and around your lips, often grouped together in patches. Cold sores generally clear up without treatment in two to four weeks. There are over-the-counter, prescription and alternative medicine treatments that may speed the healing process, [...] (Source: News from Mayo Clinic)
Source: News from Mayo Clinic - January 18, 2019 Category: Databases & Libraries Source Type: news

MTN researchers begin safety study of a 90-day vaginal ring containing tenofovir
(Microbicide Trials Network) A vaginal ring designed to protect women against both HIV and herpes simplex virus type 2 (HSV-2) is being tested in a new study that aims to determine whether its use for three months is safe. The Phase I study, taking place at three U.S. trial sites, is one of two studies evaluating full 90-day use of the ring, which contains an antiretroviral drug called tenofovir, and the first to enroll participants. (Source: EurekAlert! - Infectious and Emerging Diseases)
Source: EurekAlert! - Infectious and Emerging Diseases - January 16, 2019 Category: Infectious Diseases Source Type: news

Detection of HSV and VZV by Molecular Methods Detection of HSV and VZV by Molecular Methods
This study compared multiplex nucleic acid amplification tests that detect and differentiate herpes simplex virus and varicella-zoster virus with traditional virologic assays.American Journal of Clinical Pathology (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - January 14, 2019 Category: Consumer Health News Tags: Pathology & Lab Medicine Journal Article Source Type: news

Medical News Today: Herpes simplex: Everything you need to know
Herpes simplex is a very common virus that affects billions of people globally. It can cause sores around the mouth or on the genitals and surrounding areas. Learn more about herpes simplex here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - December 10, 2018 Category: Consumer Health News Tags: Infectious Diseases / Bacteria / Viruses Source Type: news

Medical News Today: What is herpes esophagitis?
Esophagitis is swelling and irritation of the food pipe, or esophagus. Herpes esophagitis is a type of esophagitis that results from infection with the herpes simplex virus. This condition is rare and usually only occurs in people with a weakened immune system. Learn more here. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - November 22, 2018 Category: Consumer Health News Tags: GastroIntestinal / Gastroenterology Source Type: news

How to get rid of a cold sore: Take this daily supplement to soothe blisters says Dr Chris
HOW TO get rid of cold sores: A cold sore is a small fluid-filled blister which commonly appears on the face and can sometimes burst and crust over into a scab. Taking a daily supplement can help soothe your painful symptoms, according to Dr Chris Steele. (Source: Daily Express - Health)
Source: Daily Express - Health - October 30, 2018 Category: Consumer Health News Source Type: news