The Impact of the Pandemic on the Quality of Colorectal and Anal Cancer Care, and 2-Year Clinical Outcomes
Curr Oncol. 2024 Apr 19;31(4):2328-2340. doi: 10.3390/curroncol31040173.ABSTRACTWe undertook a retrospective study to compare the quality of care delivered to a cohort of newly diagnosed adults with colon, rectal or anal cancer during the early phase of COVID-19 (02/20-12/20) relative to the same period in the year prior (the comparator cohort), and examine the impact of the pandemic on 2-year disease progression and all-cause mortality. We observed poorer performance on a number of quality measures, such as approximately three times as many patients in the COVID-19 cohort experienced 30-day post-surgical readmission (10.5...
Source: Current Oncology - April 26, 2024 Category: Cancer & Oncology Authors: Melanie Powis Rinku Sutradhar Simron Singh Shabbir Alibhai Saidah Hack Abed Baiad Kevin Chen Huaqi Li Zuhal Mohmand Monika K Krzyzanowska Source Type: research
Multivariate data analysis of process parameters affecting the growth and productivity of stable Chinese hamster ovary cell pools expressing SARS ‐CoV‐2 spike protein as vaccine antigen in early process development
In this study, we analyze early process development data of recombinant trimeric spike protein Cumate-inducible manufacturing platform utilizing CHO stable pool as a preferred production host across three different stirred-tank bioreactor scales (0.75, 1, and 10 L). The impact of cell passage number as an indicator of cell age, methionine sulfoximine (MSX) concentration as a selection pressure, and cell seeding density was investigated using stable pools expressing three variants of concern. Multivariate data analysis with principal component analysis an d batch-wise unfolding technique was applied to evaluate the effec...
Source: Biotechnology Progress - April 26, 2024 Category: Biotechnology Authors: Sebastian ‐Juan Reyes,
Lucas Lemire,
Raul‐Santiago Molina,
Marjolaine Roy,
Helene L'Ecuyer‐Coelho,
Yuliya Martynova,
Brian Cass,
Robert Voyer,
Yves Durocher,
Olivier Henry,
Phuong Lan Pham Tags: RESEARCH ARTICLE Source Type: research
Where are services regarding sexual minorities and psychological therapies post-COVID in 2024? A mixed-method systematised review
Matt Broadway-Horner Mental Health and Social Inclusion, Vol. ahead-of-print, No. ahead-of-print, pp.- Since COVID-19, many services have burgeoned within the UK, but what about sexual minorities? Since the last review, there are appropriate therapies, but there is often inadequate research. The purpose of this mixed-method review synthesis looking into the efficacy of psychological therapies for sexual minorities. Seven studies were found in total.A mixed-method review synthesis, three studies looking into the efficacy of psychological therapies for sexual minorities and four studies addressing the experiences of sexual ...
Source: Mental Health and Social Inclusion - April 26, 2024 Category: Psychiatry Authors: Matt Broadway-Horner Source Type: research
Viruses, Vol. 16, Pages 690: Challenges in Treating Pediatric Cancer Patients during the COVID-19 Pandemic: Balancing Risks and Care
es-Espíndola
The COVID-19 pandemic has resulted in millions of fatalities worldwide. The case of pediatric cancer patients stands out since, despite being considered a population at risk, few studies have been carried out concerning symptom detection or the description of the mechanisms capable of modifying the course of the COVID-19 disease, such as the interaction and response between the virus and the treatment given to cancer patients. By synthesizing existing studies, this paper aims to expose the treatment challenges for pediatric patients with COVID-19 in an oncology context. Additionally, this updated review i...
Source: Viruses - April 26, 2024 Category: Virology Authors: Ch ávez-Pacheco Castillejos-L ópez Laura M. Hern ández-Regino Velasco-Hidalgo Zapata-Tarres Correa-Carranza Rosario-M éndez Barrientos-R íos Aquino-G álvez Torres-Esp índola Tags: Review Source Type: research
Correction: Longitudinal analysis of home food production and food sharing behavior in Japan: multiple benefits of local food systems and the recent impact of the COVID-19 pandemic
(Source: Sustainability Science)
Source: Sustainability Science - April 26, 2024 Category: Science Source Type: research
Telemedicine for adolescent and young adult long-acting reversible contraception post-insertion visits: outcomes over 1 year
Telemedicine for long-acting reversible contraception (LARC) care is understudied given the rapid implementation of these services in response to the COVID-19 pandemic. We compared outcomes over 1 year of adolescents and young adults (AYAs) attending a LARC post-insertion visit via telemedicine versus in person. (Source: Journal of Pediatric and Adolescent Gynecology)
Source: Journal of Pediatric and Adolescent Gynecology - April 26, 2024 Category: OBGYN Authors: Amanda E. Bryson, Carly E. Milliren, Sarah A. Golub, Sofya Maslyanskaya, Michelle Escovedo, Claudia Borzutzky, Sarah A.B. Pitts, Amy D. DiVasta Source Type: research
Cancers, Vol. 16, Pages 1673: COVID-19 and Cancer Detection in Russia
In this study, we analyzed the impact of the expected reduction in screening intensity on morbidity and mortality from certain malignancies. Cumulative data from the Russian National Cancer Registry available from 2000 to 2022 were analyzed. It was noted that there has been no noticeable effect of the COVID-19 lockdowns on mortality rates from breast, prostate, renal, or thyroid cancers. At the same time, the detectable incidence decreased markedly in 2020 at the time of the lockdowns and then returned to pre-pandemic levels in 2022. At the moment, there is no sufficient reason to believe that skipping screening tests in 2...
Source: Cancers - April 26, 2024 Category: Cancer & Oncology Authors: Andrey Sudarikov Tags: Communication Source Type: research
Evaluation of the internet-based intervention “Selfapy” in participants with unipolar depression and the impact on quality of life: a randomized, parallel group study
ConclusionSelfapy proved to positively affect psychological and physical QOL in a sample of participants suffering from depressive disorders and can therefore be considered an effective and highly scalable therapeutic tool. The pattern of results might partly be attributable to effects of the COVID-19 pandemic and public health measures that coincided with the trial.Trial registration: German Clinical Trials Register (DRKS): DRKS00017191. Registered June 14th, 2019,https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00017191. (Source: Quality of Life Research)
Source: Quality of Life Research - April 25, 2024 Category: Health Management Source Type: research
Can science find ways to ease loneliness?
Related podcast
The science of loneliness, making one of organic chemistry’s oldest reactions safer, and a new book series
BY
Sarah Crespi
,
Kelly Servick
,
Ariana Remmel
,
Valerie Thompson
,
Angela Saini
Podcast
25 Apr 2024
One Wednesday in May 2023, a small group gathered at an outdoor café in Barcelona, Spain, sipping coffee in t...
Source: Science of Aging Knowledge Environment - April 25, 2024 Category: Geriatrics Source Type: research
Clinical features of patients with rheumatic and musculoskeletal diseases during the coronavirus disease 2019 pandemic and the association of its relapse with infection: Across ‐sectional study
ConclusionPatients with RMDs were at lower risk of symptoms of COVID-19. Rheumatic and musculoskeletal disease patients experience a higher risk of relapse especially when they adjust medications during COVID-19 infection. The long-term prognosis of infected RMDs patients need further investigation. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - April 25, 2024 Category: Rheumatology Authors: Yuqi Zhang,
Peijun Xu,
Jianlin Huang,
Zaiying Hu Tags: ORIGINAL ARTICLE Source Type: research
Stepping into the future of behavioral health: Opportunities, challenges, and possibilities
Am J Orthopsychiatry. 2024 Apr 25. doi: 10.1037/ort0000743. Online ahead of print.ABSTRACTTo improve our practices of today and to overcome the problems that confront us at present, the behavioral health field must anticipate what the future is likely to bring. Such foresight is particularly important right now because of the changes and disruptions that have occurred due to the COVID-19 pandemic over the past 3 years. We begin by recounting major developments in the mental health field since the founding of the National Institute of Mental Health (NIMH) more than 70 years ago, including some firsthand experiences of the s...
Source: The American Journal of Orthopsychiatry - April 25, 2024 Category: Psychiatry Authors: Ronald W Manderscheid Amy A Ward Source Type: research
Loneliness and Mortality Risk Among Cancer Survivors in the United States: A Retrospective, Longitudinal Study
CONCLUSIONS: Elevated loneliness was associated with a higher mortality risk among cancer survivors. Programs to screen for loneliness among cancer survivors and to provide resources and support are warranted, especially considering the widespread social distancing that occurred during the COVID-19 pandemic.PMID:38663443 | DOI:10.6004/jnccn.2023.7114 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - April 25, 2024 Category: Cancer & Oncology Authors: Jingxuan Zhao Jennifer B Reese Xuesong Han K Robin Yabroff Source Type: research
Perspectives on the implementation of health informatics curricula frameworks
CONCLUSIONS: The proposed implementation framework serves as a roadmap for successful health informatics implementation into health professional curricula. Prioritising engagement with health services and digital health industry is essential to ensure the relevance of implemented informatics curricula for the future workforce, acknowledging the variability in placement experiences and their influence on informatics exposure, experience, and learning.PMID:38662767 | DOI:10.1080/10376178.2024.2343010 (Source: Contemporary Nurse)
Source: Contemporary Nurse - April 25, 2024 Category: Nursing Authors: Zerina Lokmic-Tomkins Kalpana Raghunathan Helen Almond Richard G Booth Susan G McBride Mari Tietze Michelle Honey Paula Procter Monica Peddle Lisa McKenna Source Type: research
What Is Light in Dark Times?
Perspect Biol Med. 2023;66(3):492-501. doi: 10.1353/pbm.2023.a902041.ABSTRACTAlisse Waterston and Charlotte Corden's Light in Dark Times (2020) began as an address by the president of the American Anthropological Association and was transformed into "a work of art and anthropology" by a member of the audience. The result was a coauthored book-length graphic essay that is expansive in subject matter, and in the representation of ideas, scholars, and questions about what it means to be human and how we will pass the time that is given us on earth. Light and dark are central to the visual representations that serve as the bac...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: Sue E Estroff Source Type: research
Science in the Public Mind: < em > sources and consequences of antipathy < /em >
Perspect Biol Med. 2023;66(3):468-477. doi: 10.1353/pbm.2023.a902039.ABSTRACTPublic attitudes toward science in the United States can profoundly affect national well-being, and even national security. We live in a time when these attitudes are considerably more negative than usual. This critical assessment identifies a number of contributors to public antipathy toward science, some of which are intrinsic to the nature of science and as old as science itself, and some of which are external to science, have arisen recently, and may be unique to the present. Historic examples of scientific developments and challenges and two ...
Source: Perspectives in Biology and Medicine - April 25, 2024 Category: Medical Ethics Authors: William H Woodruff Source Type: research
