Understanding the Prevalence of Prediabetes and Diabetes in Patients With Cancer in Clinical Practice: A Real-World Cohort Study
CONCLUSIONS: Every second patient with cancer experiences preDM or DM. It is essential to foster interprofessional collaboration and to develop evidence-based practice guidelines. A better understanding of the impact of cancer treatment on the development of preDM and DM remains critical.PMID:34129522 | DOI:10.6004/jnccn.2020.7653 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - June 15, 2021 Category: Cancer & Oncology Authors: Dominik J Ose Richard Viskochil Andreana N Holowatyj Mikaela Larson Dalton Wilson William A Dunson Vikrant G Deshmukh J Ryan Butcher Belinda R Taylor Kim Svoboda Jennifer Leiser Benjamin Tingey Benjamin Haaland David W Wetter Simon J Fisher Mia Hashibe Co Source Type: research

Association Between Chronologic Age and Geriatric Assessment-Identified Impairments: Findings From the CARE Registry
CONCLUSIONS: Using chronologic age alone to identify which patients may benefit from GA is problematic. Future studies should identify screening tools that may identify patients at high risk of frailty and GA impairments.PMID:34116502 | DOI:10.6004/jnccn.2020.7679 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - June 11, 2021 Category: Cancer & Oncology Authors: Smith Giri Mustafa Al-Obaidi Alice Weaver Kelly M Kenzik Andrew McDonald Deanna Clark Crystal Young-Smith Ravi Paluri Lakshmin Nandagopal Olumide Gbolahan Mackenzi Pergolotti Smita Bhatia Grant R Williams Source Type: research

Disparate Use of Chemoradiation in Elderly Patients With Localized Anal Cancer
J Natl Compr Canc Netw. 2021 Jun 10:1-9. doi: 10.6004/jnccn.2020.7691. Online ahead of print.ABSTRACTBACKGROUND: The incidence of squamous cell carcinoma of the anus (SCCA) is increasing, particularly among the elderly (age ≥65 years). We sought to compare patterns of care for the treatment of SCCA in elderly versus nonelderly patients.METHODS: Data for patients with stages I-III SCCA diagnosed from 2004 through 2015 were obtained from the National Cancer Database. Patients were categorized as having received standard-of-care (SOC) chemoradiation (CRT) with multiagent chemotherapy, non-SOC therapy, palliative therapy, o...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - June 10, 2021 Category: Cancer & Oncology Authors: Eric D Miller Ansel P Nalin Dayssy A Diaz Pardo Andrea L Arnett Emily Huang Alessandra C Gasior Pannaga Malalur Hui-Zi Chen Terence M Williams Jose G Bazan Source Type: research

Clinicopathologic Features, Treatment Response, and Outcomes of Immune Checkpoint Inhibitor-Related Esophagitis
J Natl Compr Canc Netw. 2021 Jan 1:1-9. Online ahead of print.NO ABSTRACTPMID:34102607 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - June 8, 2021 Category: Cancer & Oncology Authors: Kavea Panneerselvam Rajan N Amin Dongguang Wei Dongfeng Tan Phillip J Lum Hao Chi Zhang David M Richards Mehmet Altan Petros Grivas John A Thompson Anusha S Thomas Yinghong Wang Source Type: research

Risk of Cancer-Specific Death for Patients Diagnosed With Neuroendocrine Tumors: A Population-Based Analysis
CONCLUSIONS: Among all NETs, the risk of dying of cancer was higher than that of dying of other causes. Heterogeneity exists by primary NET site. Some patients with nonmetastatic NETs are more likely to die of noncancer causes than of cancer causes. This information is important for counseling, decision-making, and design of future trials. Cancer-specific mortality should be included in outcomes when assessing treatment strategies.PMID:34087785 | DOI:10.6004/jnccn.2020.7666 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - June 4, 2021 Category: Cancer & Oncology Authors: Julie Hallet Calvin Law Simron Singh Alyson Mahar Sten Myrehaug Victoria Zuk Haoyu Zhao Wing Chan Angela Assal Natalie Coburn Source Type: research

Diagnostic and Therapeutic Delays in Patients With Hepatocellular Carcinoma
CONCLUSIONS: Diagnostic and therapeutic delays exceeding 3 months are common in patients with HCC; however, observed treatment delays do not seem to significantly impact overall survival.PMID:34077908 | DOI:10.6004/jnccn.2020.7689 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - June 2, 2021 Category: Cancer & Oncology Authors: Ashwin Rao Nicole E Rich Jorge A Marrero Adam C Yopp Amit G Singal Source Type: research

National Quality Measure Compliance for Palliative Bone Radiation Among Patients With Metastatic Non-Small Cell Lung Cancer
CONCLUSIONS: Among patients treated for metastatic non-small cell lung cancer, compliance with NQF 1822 increased over time. Although extended fractionation constituted a majority of noncompliant treatment courses, a substantial proportion also involved shorter courses.PMID:34044365 | DOI:10.6004/jnccn.2020.7688 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 27, 2021 Category: Cancer & Oncology Authors: Stephen R Grant Benjamin D Smith Lauren E Colbert Qunyh-Nhu Nguyen James B Yu Steven H Lin Aileen B Chen Source Type: research

Clinical Activity of Selitrectinib in a Patient With Mammary Analogue Secretory Carcinoma of the Parotid Gland With Secondary Resistance to Entrectinib
J Natl Compr Canc Netw. 2021 May 2;19(5):478-482. doi: 10.6004/jnccn.2021.7022. Print 2021 May.ABSTRACTNTRK gene fusions are found in
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Vaia Florou Christopher Nevala-Plagemann Jonathan Whisenant Patricia Maeda Glynn W Gilcrease Ignacio Garrido-Laguna Source Type: research

Open Notes Are Here: Are We Ready?
J Natl Compr Canc Netw. 2021 May 1;19(5):477. doi: 10.6004/jnccn.2021.0024.NO ABSTRACTPMID:34030126 | DOI:10.6004/jnccn.2021.0024 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Margaret Tempero Source Type: research

Authors' Reply: To Letter to the Editor by Guo and Liu
J Natl Compr Canc Netw. 2021 May;19(5):xxviii. doi: 10.6004/jnccn.2021.7019.NO ABSTRACTPMID:34030127 | DOI:10.6004/jnccn.2021.7019 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Angela Pecoraro Francesco Porpiglia Pierre I Karakiewicz Source Type: research

NCCN Guidelines ® Insights: Breast Cancer, Version 4.2021
J Natl Compr Canc Netw. 2021 May 1;19(5):484-493. doi: 10.6004/jnccn.2021.0023.ABSTRACTThe NCCN Guidelines for Breast Cancer include up-to-date guidelines for clinical management of patients with carcinoma in situ, invasive breast cancer, Paget disease, phyllodes tumor, inflammatory breast cancer, male breast cancer, and breast cancer during pregnancy. These guidelines are developed by a multidisciplinary panel of representatives from NCCN Member Institutions with breast cancer-focused expertise in the fields of medical oncology, surgical oncology, radiation oncology, pathology, reconstructive surgery, and patient advocacy...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: William J Gradishar Meena S Moran Jame Abraham Rebecca Aft Doreen Agnese Kimberly H Allison Sarah L Blair Harold J Burstein Chau Dang Anthony D Elias Sharon H Giordano Matthew P Goetz Lori J Goldstein Sara A Hurvitz Steven J Isakoff Rachel C Jankowitz Sar Source Type: research

Leveraging Surgical Case Volume in Improving Cancer Care Outcomes: Where Do We Go From Here?
J Natl Compr Canc Netw. 2021 May;19(5):577-579. doi: 10.6004/jnccn.2021.7045.NO ABSTRACTPMID:34030129 | DOI:10.6004/jnccn.2021.7045 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Henry Soo-Min Park Source Type: research

Letter to the Editor: T1a 0- to 2-cm Small Renal Masses
J Natl Compr Canc Netw. 2021 May;19(5):xxviii. doi: 10.6004/jnccn.2021.7020.NO ABSTRACTPMID:34030130 | DOI:10.6004/jnccn.2021.7020 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Boda Guo Ming Liu Source Type: research

Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology
This article discusses the NCCN Guidelines recommendations for HCC.PMID:34030131 | DOI:10.6004/jnccn.2021.0022 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Al B Benson Michael I D'Angelica Daniel E Abbott Daniel A Anaya Robert Anders Chandrakanth Are Melinda Bachini Mitesh Borad Daniel Brown Adam Burgoyne Prabhleen Chahal Daniel T Chang Jordan Cloyd Anne M Covey Evan S Glazer Lipika Goyal William G Hawkins R Source Type: research

Integration of Systemic and Liver-Directed Therapies for Locally Advanced Hepatocellular Cancer: Harnessing Potential Synergy for New Therapeutic Horizons
This article reviews the treatment options available to patients with locally advanced HCC and discusses the rationale, ongoing trials, and future prospects for combining locoregional and systemic therapy in both the definitive and neoadjuvant settings.PMID:34030132 | DOI:10.6004/jnccn.2021.7037 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Eric H Bent Eric Wehrenberg-Klee Eugene J Koay Lipika Goyal Jennifer Y Wo Source Type: research

Clinical Activity of Selitrectinib in a Patient With Mammary Analogue Secretory Carcinoma of the Parotid Gland With Secondary Resistance to Entrectinib
J Natl Compr Canc Netw. 2021 May 2;19(5):478-482. doi: 10.6004/jnccn.2021.7022. Print 2021 May.ABSTRACTNTRK gene fusions are found in
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Vaia Florou Christopher Nevala-Plagemann Jonathan Whisenant Patricia Maeda Glynn W Gilcrease Ignacio Garrido-Laguna Source Type: research

Open Notes Are Here: Are We Ready?
J Natl Compr Canc Netw. 2021 May 1;19(5):477. doi: 10.6004/jnccn.2021.0024.NO ABSTRACTPMID:34030126 | DOI:10.6004/jnccn.2021.0024 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Margaret Tempero Source Type: research

Authors' Reply: To Letter to the Editor by Guo and Liu
J Natl Compr Canc Netw. 2021 May;19(5):xxviii. doi: 10.6004/jnccn.2021.7019.NO ABSTRACTPMID:34030127 | DOI:10.6004/jnccn.2021.7019 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Angela Pecoraro Francesco Porpiglia Pierre I Karakiewicz Source Type: research

NCCN Guidelines ® Insights: Breast Cancer, Version 4.2021
J Natl Compr Canc Netw. 2021 May 1;19(5):484-493. doi: 10.6004/jnccn.2021.0023.ABSTRACTThe NCCN Guidelines for Breast Cancer include up-to-date guidelines for clinical management of patients with carcinoma in situ, invasive breast cancer, Paget disease, phyllodes tumor, inflammatory breast cancer, male breast cancer, and breast cancer during pregnancy. These guidelines are developed by a multidisciplinary panel of representatives from NCCN Member Institutions with breast cancer-focused expertise in the fields of medical oncology, surgical oncology, radiation oncology, pathology, reconstructive surgery, and patient advocacy...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: William J Gradishar Meena S Moran Jame Abraham Rebecca Aft Doreen Agnese Kimberly H Allison Sarah L Blair Harold J Burstein Chau Dang Anthony D Elias Sharon H Giordano Matthew P Goetz Lori J Goldstein Sara A Hurvitz Steven J Isakoff Rachel C Jankowitz Sar Source Type: research

Leveraging Surgical Case Volume in Improving Cancer Care Outcomes: Where Do We Go From Here?
J Natl Compr Canc Netw. 2021 May;19(5):577-579. doi: 10.6004/jnccn.2021.7045.NO ABSTRACTPMID:34030129 | DOI:10.6004/jnccn.2021.7045 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Henry Soo-Min Park Source Type: research

Letter to the Editor: T1a 0- to 2-cm Small Renal Masses
J Natl Compr Canc Netw. 2021 May;19(5):xxviii. doi: 10.6004/jnccn.2021.7020.NO ABSTRACTPMID:34030130 | DOI:10.6004/jnccn.2021.7020 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Boda Guo Ming Liu Source Type: research

Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology
This article discusses the NCCN Guidelines recommendations for HCC.PMID:34030131 | DOI:10.6004/jnccn.2021.0022 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Al B Benson Michael I D'Angelica Daniel E Abbott Daniel A Anaya Robert Anders Chandrakanth Are Melinda Bachini Mitesh Borad Daniel Brown Adam Burgoyne Prabhleen Chahal Daniel T Chang Jordan Cloyd Anne M Covey Evan S Glazer Lipika Goyal William G Hawkins R Source Type: research

Integration of Systemic and Liver-Directed Therapies for Locally Advanced Hepatocellular Cancer: Harnessing Potential Synergy for New Therapeutic Horizons
This article reviews the treatment options available to patients with locally advanced HCC and discusses the rationale, ongoing trials, and future prospects for combining locoregional and systemic therapy in both the definitive and neoadjuvant settings.PMID:34030132 | DOI:10.6004/jnccn.2021.7037 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Eric H Bent Eric Wehrenberg-Klee Eugene J Koay Lipika Goyal Jennifer Y Wo Source Type: research

Clinical Activity of Selitrectinib in a Patient With Mammary Analogue Secretory Carcinoma of the Parotid Gland With Secondary Resistance to Entrectinib
J Natl Compr Canc Netw. 2021 May 2;19(5):478-482. doi: 10.6004/jnccn.2021.7022. Print 2021 May.ABSTRACTNTRK gene fusions are found in
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Vaia Florou Christopher Nevala-Plagemann Jonathan Whisenant Patricia Maeda Glynn W Gilcrease Ignacio Garrido-Laguna Source Type: research

Open Notes Are Here: Are We Ready?
J Natl Compr Canc Netw. 2021 May 1;19(5):477. doi: 10.6004/jnccn.2021.0024.NO ABSTRACTPMID:34030126 | DOI:10.6004/jnccn.2021.0024 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Margaret Tempero Source Type: research

Authors' Reply: To Letter to the Editor by Guo and Liu
J Natl Compr Canc Netw. 2021 May;19(5):xxviii. doi: 10.6004/jnccn.2021.7019.NO ABSTRACTPMID:34030127 | DOI:10.6004/jnccn.2021.7019 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Angela Pecoraro Francesco Porpiglia Pierre I Karakiewicz Source Type: research

NCCN Guidelines ® Insights: Breast Cancer, Version 4.2021
J Natl Compr Canc Netw. 2021 May 1;19(5):484-493. doi: 10.6004/jnccn.2021.0023.ABSTRACTThe NCCN Guidelines for Breast Cancer include up-to-date guidelines for clinical management of patients with carcinoma in situ, invasive breast cancer, Paget disease, phyllodes tumor, inflammatory breast cancer, male breast cancer, and breast cancer during pregnancy. These guidelines are developed by a multidisciplinary panel of representatives from NCCN Member Institutions with breast cancer-focused expertise in the fields of medical oncology, surgical oncology, radiation oncology, pathology, reconstructive surgery, and patient advocacy...
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: William J Gradishar Meena S Moran Jame Abraham Rebecca Aft Doreen Agnese Kimberly H Allison Sarah L Blair Harold J Burstein Chau Dang Anthony D Elias Sharon H Giordano Matthew P Goetz Lori J Goldstein Sara A Hurvitz Steven J Isakoff Rachel C Jankowitz Sar Source Type: research

Leveraging Surgical Case Volume in Improving Cancer Care Outcomes: Where Do We Go From Here?
J Natl Compr Canc Netw. 2021 May;19(5):577-579. doi: 10.6004/jnccn.2021.7045.NO ABSTRACTPMID:34030129 | DOI:10.6004/jnccn.2021.7045 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Henry Soo-Min Park Source Type: research

Letter to the Editor: T1a 0- to 2-cm Small Renal Masses
J Natl Compr Canc Netw. 2021 May;19(5):xxviii. doi: 10.6004/jnccn.2021.7020.NO ABSTRACTPMID:34030130 | DOI:10.6004/jnccn.2021.7020 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Boda Guo Ming Liu Source Type: research

Hepatobiliary Cancers, Version 2.2021, NCCN Clinical Practice Guidelines in Oncology
This article discusses the NCCN Guidelines recommendations for HCC.PMID:34030131 | DOI:10.6004/jnccn.2021.0022 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Al B Benson Michael I D'Angelica Daniel E Abbott Daniel A Anaya Robert Anders Chandrakanth Are Melinda Bachini Mitesh Borad Daniel Brown Adam Burgoyne Prabhleen Chahal Daniel T Chang Jordan Cloyd Anne M Covey Evan S Glazer Lipika Goyal William G Hawkins R Source Type: research

Integration of Systemic and Liver-Directed Therapies for Locally Advanced Hepatocellular Cancer: Harnessing Potential Synergy for New Therapeutic Horizons
This article reviews the treatment options available to patients with locally advanced HCC and discusses the rationale, ongoing trials, and future prospects for combining locoregional and systemic therapy in both the definitive and neoadjuvant settings.PMID:34030132 | DOI:10.6004/jnccn.2021.7037 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 24, 2021 Category: Cancer & Oncology Authors: Eric H Bent Eric Wehrenberg-Klee Eugene J Koay Lipika Goyal Jennifer Y Wo Source Type: research

Use of Circulating Tumor DNA for the Clinical Management of Metastatic Castration-Resistant Prostate Cancer: A Multicenter, Real-World Study
CONCLUSIONS: Our study explored the genomic landscape of Chinese patients with mCRPC at different treatment stages using minimally invasive methods and evaluated the clinical implications of the driver genomic alterations on patients' response to the most widely used therapies for mCRPC. We observed a significantly higher alteration frequency of CDK12 in our cohort compared with the SU2C-PCF cohort.PMID:33990090 | DOI:10.6004/jnccn.2020.7663 (Source: Journal of the National Comprehensive Cancer Network : JNCCN)
Source: Journal of the National Comprehensive Cancer Network : JNCCN - May 14, 2021 Category: Cancer & Oncology Authors: Baijun Dong Liancheng Fan Bin Yang Wei Chen Yonghong Li Kaijie Wu Fengbo Zhang Haiying Dong Huihua Cheng Jiahua Pan Yinjie Zhu Chenfei Chi Liang Dong Jianjun Sha Lei Li Xudong Yao Wei Xue Source Type: research