Will rheumatologists ever pick up the arthroscope again?
AbstractConditions prompting physicians and surgeons first adapting endoscopes to peer into joints were mainly the sort of synovial conditions that would concern today's rheumatologists. Rheumatologists were among the pre-World War II pioneers developing and documenting arthroscopy. The post-War father of modern arthroscopy, Watanabe, found rheumatologists among his early students, who took back the technique to their home countries, teaching orthopedists and rheumatologists alike. Rheumatologists described and analyzed the intra-articular features of their common diseases in the ’60s and ’70s. A groundswell of...
Source: International Journal of Rheumatic Diseases - July 29, 2021 Category: Rheumatology Authors: Robert W. Ike, Kenneth C. Kalunian Tags: INVITED REVIEW Source Type: research

Fibromyalgia in HIV ‐positive patients in Nigeria: A cross‐sectional prospective study
AbstractBackgroundFibromyalgia is a chronic pain syndrome of unknown etiology characterized by chronic widespread musculoskeletal pain and tenderness. It affects the quality of life of patients and has been associated with the human immunodeficiency virus (HIV). The study aimed to determine the prevalence of fibromyalgia in HIV-positive patients and assess the effect of fibromyalgia on their functional status.MethodologyThis was a cross-sectional study comprising 160 treatment-naive HIV-positive patients and 160 age- and sex-matched HIV-negative controls. The diagnosis of fibromyalgia was based on the 2011 modification of ...
Source: International Journal of Rheumatic Diseases - July 29, 2021 Category: Rheumatology Authors: Airenakho Emorinken, Mercy Ofunami Dic ‐Ijiewere, Cyril Oshomah Erameh, Asuwemhe Johnson Ugheoke, Folasade Ojuolape Agbebaku, Oluwaseun Remi Agbadaola Tags: ORIGINAL ARTICLE Source Type: research

Serial administration of rhBMP ‐2 and alendronate enhances the differentiation of osteoblasts
AbstractAimThe incorporation of growth factors is an effective strategy to accelerate bone induction. Bone morphogenetic protein-2 (BMP-2) promotes osteoblast differentiation and induces bone formation. Alendronate (ALN) is an osteoclast deactivation drug. We investigated the effect of serial administration of recombinant human BMP-2 (rhBMP-2) and ALN on osteoblast differentiation.MethodsThe effect of serial administration of rhBMP-2 (0-150  ng/mL) and ALN (0-15 µmol/L) on the viability and differentiation of a clonal murine calvarial cell line, MC3T3-E1, was evaluated at various concentrations and for diff...
Source: International Journal of Rheumatic Diseases - July 29, 2021 Category: Rheumatology Authors: Sang ‐Hyon Kim, Hye‐Jung Choi, Dae Sung Yoon, Chang‐Nam Son Tags: ORIGINAL ARTICLE Source Type: research

Self ‐concept and body image of people living with lupus: A systematic review
ConclusionsThe dimensions of self-concept and body image are essential for assessing the quality of life of individuals with lupus. The formation of a adjusted self-concept can be managed by health professionals supporting these people. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 28, 2021 Category: Rheumatology Authors: Larissa Rodrigues, Maria M. F. Sim ‐Sim, Luis Sousa, Débora B. Faria‐Schützer, Fernanda G. Surita Tags: REVIEW Source Type: research

Epidemiology of Takayasu arteritis in Shanghai: A hospital ‐based study and systematic review
ConclusionsThe prevalence and incidence of TAK in Shanghai was at moderate to high levels among the previous reports. The disease burden varied globally among racial populations. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 27, 2021 Category: Rheumatology Authors: Ying Sun, Meng ‐meng Yin, Li‐li Ma, Xiao‐min Dai, Liang‐jing Lv, Xiao‐xiang Chen, Shuang Ye, Ting Li, Jie Chen, Dong‐bao Zhao, Rui‐na Kong, Qiang‐hua Wei, Guang‐hui Yang, Su‐gang Gong, Cheng‐de Yang, Hong‐lei Liu, Y Tags: ORIGINAL ARTICLE Source Type: research

What is behind the elevated neutrophil to lymphocyte ratio in glucocorticoid ‐resistant polymyalgia rheumatica?
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 25, 2021 Category: Rheumatology Authors: Hiroshi Ito Tags: CORRESPONDENCE Source Type: research

Coexistence of Takayasu arteritis and chronic myeloid leukemia: Coincidental or paraneoplastic phenomenon?
AbstractVasculitis may rarely be seen in the course of myeloproliferative neoplasms (MPN). In vasculitis associated with hematological diseases, mostly small- and medium-vessel involvement is expected, aortitis is very rare. It is not exactly known whether large-vessel vasculitis associated with MPN is a paraneoplastic phenomenon or coincidental. We aimed to present an uncommon case diagnosed with chronic myeloid leukemia and Takayasu arteritis concurrently. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 24, 2021 Category: Rheumatology Authors: Tuba Yuce Inel, Aytac Gulcu, Ali Karakas, Elcin Erdogan Yucel, Fatos Onen Tags: APLAR GRAND ROUND CASE Source Type: research

The relationship between common variants in the DPEP1 gene and the susceptibility and clinical severity of osteoarthritis
ConclusionWe reported a common DNA variant in theDPEP1 gene that contributes to the risk of OA, providing additional evidence that theDPEP1 gene plays a significant role in the pathological mechanisms of OA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 22, 2021 Category: Rheumatology Authors: Ziqi Zhang, Yufeng Mei, Min Feng, Chunsheng Wang, Pei Yang, Run Tian Tags: ORIGINAL ARTICLE Source Type: research

Development and validation of a Beh çet's Disease Damage Index for adults with BD: An Explicit, Composite and Rated (ECR) tool
ConclusionThe proposed BDI represents a new robust and potentially useful tool when dealing with BD chronic status. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 21, 2021 Category: Rheumatology Authors: Tamer A. Gheita, Nevin Hammam, Samar M. Fawzy, Eiman Abd El ‐Latif, Iman I. El‐Gazzar, Nermeen Samy, Dina H. El‐Hammady, Rasha Abdel Noor, Emad El‐Shebini, Amany R. El‐Najjar, Nahla N. Eesa, Mohamed N. Salem, Soha E. Ibrahim, Dina F Tags: ORIGINAL ARTICLE Source Type: research

Static foot posture and its relation to clinical variables in ankylosing spondylitis
AbstractAimPostural abnormalities of the foot are common in rheumatic diseases. Static foot posture is a poorly studied clinical parameter in ankylosing spondylitis (AS). The aim of the study was to evaluate static foot posture in patients with AS and to determine the potential impact of clinical variables on foot posture.MethodFifty patients with AS and 40 age- and sex-matched healthy controls were enrolled in the study. Disease activity was measured using the Ankylosing Spondylitis Disease Activity Score. Axial mobility was evaluated with the Bath Ankylosing Spondylitis Metrology Index three-point answer scale. Functiona...
Source: International Journal of Rheumatic Diseases - July 20, 2021 Category: Rheumatology Authors: Neslihan Gokcen, Aylin Sariyildiz, Ilke Coskun Benlidayi Tags: ORIGINAL ARTICLE Source Type: research

Vale Dr Christina Ann Boros (1966 ‐2021)
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 20, 2021 Category: Rheumatology Authors: Davinder Singh ‐Grewal Tags: ANNOUNCEMENT Source Type: research

Prevalence of obstructive sleep apnea among patients with rheumatoid arthritis and its association with age and body mass index: A systematic review and meta ‐analysis
ConclusionPrevalence of OSA among the RA cohort was 29.8% with significant heterogeneity. However, the prevalence was 45.3% when studies were restricted to the OSA diagnosis based on the Berlin questionnaire with very low heterogeneity. Higher BMI is the principal risk factor of OSA development in RA. Hence, controlling BMI could be a preventive strategy for OSA among RA patients. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 19, 2021 Category: Rheumatology Authors: Bhaskar Thakur, Mona Pathak, Pratima Singh, Prasanta Padhan Tags: ORIGINAL ARTICLE Source Type: research

Effects of supervised exercise program and home exercise program in patients with systemic sclerosis: A randomized controlled trial
AbstractAimTo compare the effects of supervised exercise and home exercise program in patients with systemic sclerosis (SSc).MethodsThirty-seven SSc patients were included. Patients with SSc were allocated into 2 groups as supervised and home exercise. Breathing, aerobic and resistance exercises were performed with a physiotherapist for 12  weeks in the supervised exercise group. Breathing, posture and aerobic exercises were given to the home exercise group as a home program for 12 weeks. All patients were assessed at baseline and 12 weeks later in terms of functional capacity, pulmonary functions, respirato...
Source: International Journal of Rheumatic Diseases - July 16, 2021 Category: Rheumatology Authors: Hazal Yakut, Sevgi Özalevli, Ridvan Aktan, Aylin Özgen Alpaydın, Ahmet Merih Birlik, Gerçek Can Tags: ORIGINAL ARTICLE Source Type: research

A Benchmarking Study Evaluating Axial Spondyloarthritis Burden in Spain and Other European Countries. Results from the Spanish Atlas and the European Map of Axial Spondyloarthritis (EMAS) Studies
AbstractAimTo compare the burden of disease in Spanish patients with axial spondyloarthritis (axSpA) vs other European countries (OEC).MethodsData from 2846 unselected patients from the European Map of Axial Spondyloarthritis (EMAS) and the Atlas of Axial Spondyloarthritis in Spain (Atlas) were collected through online surveys. Comparative analysis was carried out between Spanish patients (2016) and patients from 12 OEC ( 2017-2018). Socio-demographic characteristics, life habits, and patient-reported outcomes (Bath Ankylosing Spondylitis Disease Activity Index 0-10, spinal stiffness 3-12, functional limitation 0-54, the 1...
Source: International Journal of Rheumatic Diseases - July 16, 2021 Category: Rheumatology Authors: Marco Garrido ‐Cumbrera, Jordi Gratacós, Eduardo Collantes‐Estevez, Pedro Zarco‐Montejo, Carlos Sastre, Laura Christen, Sergio Sanz‐Gómez, José Correa‐Fernández, Victoria Navarro‐Compán Tags: ORIGINAL ARTICLE Source Type: research

Performance of myositis ‐specific antibodies detected on myositis line immunoassay to diagnose and sub‐classify patients with suspected idiopathic inflammatory myopathy, a retrospective records‐based review
ConclusionIncreased MSA signal strength on myositis LIA and the presence of an expected IIF pattern were associated with IIM diagnosis. Test performance was non-significantly improved by these methods. Prevalence of IIM in this patient cohort was low; it is not excluded that LIA performance could be improved by these methods in a higher prevalence cohort. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 12, 2021 Category: Rheumatology Authors: Thomas J. Beaton, David Gillis, Kerri Prain, Karen Morwood, James Anderson, John Goddard, Timothy Baird Tags: ORIGINAL ARTICLE Source Type: research

Clinical characteristics of non ‐radiographic axial spondyloarthritis: Results of the Korean Nonradiographic Axial SPondyloArthritis (KONASPA) data
AbstractAimTo evaluate clinical characteristics and natural history of non-radiographic axial spondyloarthritis (nr-axSpA) using KOrean Nonradiographic Axial SPondyloArthritis (KONASPA) data.MethodsData were collected from 11 centers in South Korea. A total of 278 patients with nr-axSpA from January 2018 to July 2020 were included. Demographic data, clinical features, comorbidities, disease activity, medications, and laboratory results were collected.ResultsMean age at symptom onset was 28.2  ± 14.2 years. Of 278 patients, 152 (54.7%) were male. Mean Bath Ankylosing Spondylitis Disease Activity Index ...
Source: International Journal of Rheumatic Diseases - July 12, 2021 Category: Rheumatology Authors: Hyemin Jeong, Yong ‐Gil Kim, Tae‐Hwan Kim, Tae‐Jong Kim, Min‐Chan Park, Mi Ryoung Seo, Kichul Shin, Ji Seon Oh, Sang‐Hoon Lee, Yeon‐Ah Lee, Eun Young Lee, Han Joo Baek, Hoon‐Suk Cha Tags: ORIGINAL ARTICLE Source Type: research

Your help is needed in the fight against COVID ‐19: Please contribute to the COVID‐19 Global rheumatology alliance registry
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 10, 2021 Category: Rheumatology Tags: APLAR MATTERS Source Type: research

Issue Information
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 9, 2021 Category: Rheumatology Tags: ISSUE INFORMATION Source Type: research

Interleukin ‐17 inhibitor, is it safer than tumor necrosis factor inhibitor?
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 9, 2021 Category: Rheumatology Authors: Jinxian Huang, Lijun Zhang, James C ‐C Wei Tags: EDITORIAL Source Type: research

The implication of interferon ‐γ‐producing immunocompetent cells for evaluating disease activity and severity in adult‐onset Still’s disease
ConclusionIncreased serum levels of IFN- γ, increased expression of IFN-γ in CD4+ cells, and decreased NK cell proportion correlate with disease activity in AOSD. Moreover, a lower proportion of NK cells may be useful for predicting a refractory clinical course. Meanwhile, increased serum levels of IL-6, IL-12, and IL-18 may persist afte r clinical remission. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 9, 2021 Category: Rheumatology Authors: Takanori Ichikawa, Yasuhiro Shimojima, Dai Kishida, Ken ‐ichi Ueno, Yoshiki Sekijima Tags: ORIGINAL ARTICLE Source Type: research

Prevalence and factors associated with low back pain in schoolchildren in Cameroon, sub ‐Saharan Africa
AbstractBackgroundData on the prevalence and factors associated with low back pain (LBP) in schoolchildren are scarce in Africa, particularly in sub-Saharan Africa.ObjectivesTo assess the prevalence and factors associated with LBP in schoolchildren in Cameroon.Patients and methodsWe performed a cross-sectional study in 10 randomly selected schools (public and private) in Douala, Cameroon. Using a self-administrated questionnaire, sociodemographic, usual physical activity, and clinical data were collected and all the schoolbags were weighted. Informed consent was obtained from the parents. Statistical significance was established atP 
Source: International Journal of Rheumatic Diseases - July 8, 2021 Category: Rheumatology Authors: Fernando Kemta Lekpa, Dominique Enyama, Diomede Noukeu Njinkui, Arielle Ngongang Chiedjio, Sylvain Raoul Simeni Njonnou, Christian Ngongang Ouankou, Henry Namme Luma, Simeon Pierre Choukem Tags: ORIGINAL ARTICLE Source Type: research

Interval between symptom onset and diagnosis among patients with autoimmune rheumatic diseases in a multi ‐ethnic Asian population
ConclusionA long pre-diagnosis interval was observed among patients with ARDs (especially axSpA), due largely to a long interval between symptom onset and the first visit to healthcare professionals. This highlights the importance of interventions targeting patients prior to their first visit to healthcare professionals in reducing pre-diagnosis interval. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 7, 2021 Category: Rheumatology Authors: Ling Xiang, Andrea Hsiu Ling Low, Ying Ying Leung, Warren Fong, Mihir Gandhi, Sungwon Yoon, Tang Ching Lau, Dow Rhoon Koh, Julian Thumboo Tags: ORIGINAL ARTICLE Source Type: research

Circulating CD4+  FoxP3– CXCR5– CXCR3+ PD‐1hi cells are elevated in active rheumatoid arthritis and reflect the severity of the disease
ConclusionCirculating CD4+ FoxP3– CXCR5– CXCR3+ PD-1hi cells in patients with active RA are increased and could reflect the severity of the disease, which may play a potential role in the pathogenesis of RA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 6, 2021 Category: Rheumatology Authors: Lei Zhao, Zhenxue Li, Xingyue Zeng, Changsheng Xia, Lijuan Xu, Qinzhu Xu, Ying Song, Chen Liu Tags: ORIGINAL ARTICLE Source Type: research

Sj ögren’s syndrome complicated with membranous nephropathy, a cause of coincidence?
ConclusionsIn patients with both MN and SS, PLA2R-negative MN should be considered as a secondary form. Careful screen for SLE is necessary in these patients during follow-up. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 5, 2021 Category: Rheumatology Authors: Ruiying Chen, Jia Wang, Qionghong Xie, Jun Xue, Chuanming Hao Tags: ORIGINAL ARTICLE Source Type: research

Sj ögren’s syndrome complicated with membranous nephropathy, a cause or coincidence?
ConclusionsIn patients with both MN and SS, PLA2R-negative MN should be considered as a secondary form. Careful screen for SLE is necessary in these patients during follow-up. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 5, 2021 Category: Rheumatology Authors: Ruiying Chen, Jia Wang, Qionghong Xie, Jun Xue, Chuanming Hao Tags: ORIGINAL ARTICLE Source Type: research

Acceptance and image quality of high ‐resolution peripheral quantitative computed tomography of the metacarpophalangeal joints in rheumatoid arthritis
ConclusionThe high patient acceptance adds to the feasibility of HR-pQCT imaging of MCP joints in RA. The inflatable immobilization device did not reduce motion-induced image degradation. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - July 2, 2021 Category: Rheumatology Authors: Rasmus Klose ‐Jensen, Kresten Krarup Keller, Bente Langdahl, Ellen‐Margrethe Hauge Tags: ORIGINAL ARTICLE Source Type: research

Discriminative ability of trabecular bone score over bone mineral density for vertebral and fragility fracture in patients treated with long ‐term and low‐dose glucocorticoid
This study assessed TBS and bone mineral density (BMD) in chronic GC users, defined as ≥2.5 mg/d of prednisone for>3  months (n = 89, mean age: 62.5 ± 11 years), and in controls (n = 59, mean age: 60.3 ± 9.6 years). Osteoporosis risk factors, radiographs of the thoracolumbar spine, non-VF history, osteoporosis drugs, and current/cumulative GC doses were collected. Patients were classified as high (TBS1.31), according to the fracture risk based on a recent meta-analysis.ResultsThe mean current dose and duration of GC treatment were 3.9  &pl...
Source: International Journal of Rheumatic Diseases - June 30, 2021 Category: Rheumatology Authors: Kyung ‐Ann Lee, JongSun Kim, Hyun‐joo Kim, Hyun‐Sook Kim Tags: ORIGINAL ARTICLE Source Type: research

Familial aggregation of juvenile idiopathic arthritis with other autoimmune diseases: Impact on clinical characteristics, disease activity status and disease damage
ConclusionThis study shows that autoimmune diseases cluster within families of patients with JIA with a high proportion of ERA and psoriatic arthritis. JIA patients with FHADs are likely to have more disease damage. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 29, 2021 Category: Rheumatology Authors: Sulaiman M. Al ‐Mayouf, Abeer Alrasheedi, Iman Almsellati, Soad Hashad, Khulood Khawaja, Reem Abdwani, Samia AlHashim, Mohammed Muzaffer, Hala Lotfy, Nora Almutairi Tags: ORIGINAL ARTICLE Source Type: research

Magnetic Resonance Imaging evidence of Inflammation at Interphalangeal joint of Thumb — A distinct entity in psoriatic arthritis
ConclusionGlobal MRI inflammation around the IP joint of the thumb is significantly more common in patients with PsA as compared to individuals with UIA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 29, 2021 Category: Rheumatology Authors: Ashish J Mathew, Arvind Ganapati, Jyoti Panwar, Varghese Koshy, Anu Desai, Debashish Danda Tags: ORIGINAL ARTICLE Source Type: research

Recent advances in pediatric rheumatology: January to March 2021
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 28, 2021 Category: Rheumatology Authors: Archan Sil, Prabal Barman, Surjit Singh Tags: EXPERT COMMENTS Source Type: research

Turkish version of modified Hand Mobility in Scleroderma test: A translation and validation study
This study included a total of 39 patients with systemic sclerosis (SSc) who were assessed with mHAMIS. The Cronbach's α coefficient, Kappa concordance, and intraclass correlation were respectively used to assess the internal consistency, intra- and inter-observer agreement, and inter-observer reliability of the test. The correlation between the Health Assessment Questionnaire (HAQ), the Duruoz Hand Index (DHI), an d the Turkish version of mHAMIS were evaluated.ResultsThe internal consistency of the test items was between .912 and .939. The total internal consistency of the test was excellent, with a Cronbach's alpha...
Source: International Journal of Rheumatic Diseases - June 24, 2021 Category: Rheumatology Authors: Serdar Kaymaz, Ugur Karasu, Hakan Alkan, Veli Cobankara Tags: ORIGINAL ARTICLE Source Type: research

Will the COVID ‐19 pandemic trigger future occurrence of autoimmunity like Sjögren’s syndrome?
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 22, 2021 Category: Rheumatology Authors: Kayo Masuko Tags: NOVEL HYPOTHESIS Source Type: research

Downregulation of miR ‐98‐5p expression induces interleukin‐6 expression in rheumatoid fibroblast‐like synoviocytes
ConclusionThese data suggest that manipulation of miR-98-5p, which negatively modulates IL-6 expression, may be a potential clinical approach in RA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 22, 2021 Category: Rheumatology Authors: Shujun Wang, Qin Geng, Hongju Zhang, Qing Du, Qiaofeng Wei, Yanhui Cui, Xiuying Zhang, Min Yuan Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of bone erosion in rheumatoid arthritis patients by high ‐resolution peripheral quantitative computed tomography scans: Comparison between two semi‐automated programs in a three‐dimensional setting
AbstractAimThe aim of this study was to compareOsiriX software with the previous published Medical Image Analysis Framework (MIAF) method to assess the volume of erosion in patients with rheumatoid arthritis (RA).MethodsForty RA patients underwent high-resolution peripheral quantitative computed tomography scans of the second and third metacarpophalangeal joints, and thirty-four patients with any bone erosion were enrolled. Two techniques were applied to erosion evaluation: (a) semi-automated MIAF software, and (b) semi-automated segmentation by free open-source Digital Imaging and Communications in Medicine viewer,OsiriX ...
Source: International Journal of Rheumatic Diseases - June 21, 2021 Category: Rheumatology Authors: Camille Pinto Figueiredo, Mariana Ortega Perez, Lucas Peixoto Sales, Valeria de Falco Caparbo, Rosa Maria Rodrigues Pereira Tags: ORIGINAL ARTICLE Source Type: research

Invalidation in fibromyalgia and rheumatoid arthritis and its effect on quality of life in Indian patients
AbstractAimFibromyalgia (FM) and rheumatoid arthritis (RA) patients face invalidation in the form of “discounting” and “lack of understanding”. Invalidation can have effects on the quality of life (QoL) in these patients. We planned this study to look for invalidation in FM and RA Indian patients and see the correlation between invalidation and QoL.MethodsInvalidation was measured by the Illness Invalidation Inventory (3*I) to look for “discounting” and “lack of understanding” across sources, that is, spouse, family, medical professionals, work environment. QoL was measured u...
Source: International Journal of Rheumatic Diseases - June 21, 2021 Category: Rheumatology Authors: Gurmeet Singh, Abdul Hamid Tags: ORIGINAL ARTICLE Source Type: research

Arterial evaluation of systemic sclerosis patients with Doppler ultrasound: What did we find?
ConclusionsIn this study, we examined the arteries by means of CDUS, and we detected structural alterations in the peripheral and carotid arteries. We witnessed that these macrovascular changes had a close association with certain features of SSc. We think there is a need for broader prospective studies in order to evaluate the contribution of these factors to the macrovascular changes stated in the article. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 19, 2021 Category: Rheumatology Authors: Suade Ozlem Badak, Bozkurt Gulek, Esra Kayacan Erdogan, Hulya B ınokay, Eren Erken Tags: ORIGINAL ARTICLE Source Type: research

Coronary (peri) ‐arteritis in patients with IgG4‐related disease: A case series from the Central Anatolia Region of Turkey
ConclusionCoronary arteritis is a rare but notable manifestation of IgG4-RD. Although coronary periarteritis can cause significant morbidity and mortality, it seems better results can be achieved with early diagnosis and treatment. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 17, 2021 Category: Rheumatology Authors: Gozde Kubra Yardimci, Selin Ardali Duzgun, Ertugrul Cagri Bolek, Levent Kilic, Ugur Canpolat, Tuncay Hazirolan, Kudret Aytemir, Omer Karadag Tags: ORIGINAL ARTICLE Source Type: research

Takayasu arteritis developing during the course of palmoplantar pustulosis
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 17, 2021 Category: Rheumatology Authors: Masahiro Kondo, Yohko Murakawa, Sakae Kaneko, Teruaki Iwahashi, Manabu Honda, Mayuko Moriyama Tags: CORRESPONDENCE Source Type: research

Exercise capacity in axial spondyloarthritis and associated factors: A cross ‐sectional controlled study
AbstractObjectiveTo examine the associations between exercise capacity (EC), cardiovascular (CV) risk factors and disease-related variables in axial spondyloarthritis (AxSpA) patients.MethodsIn this cross-sectional controlled study, CV risk profile data, physical activity, 10-year CV event risk estimated by the Framingham model and Ankylosing Spondylitis Disease Activity Score – C-reactive protein were recorded. A maximal treadmill exercise test by Bruce protocol was administered. Analyses of covariance were performed with adjustments for age, smoking status and physical activity level. Linear regression analysis was...
Source: International Journal of Rheumatic Diseases - June 16, 2021 Category: Rheumatology Authors: Ebru K öseoğlu Tohma, Zafer Günendi, Özden Özyemişçi Taşkıran, Gönen Mengi, Nesrin Demirsoy, Nihal Taş Tags: ORIGINAL ARTICLE Source Type: research

A comparison of Janus kinase inhibitor safety in rheumatoid arthritis
AbstractThe last decade has seen considerable advancement in the treatment options available to patients with rheumatoid arthritis (RA) through the development of oral, small molecules that target and inhibit Janus kinases (JAKi). These drugs have a rapid onset of action, disrupting the Janus kinase/signal transducer and activator of transcription pathway and preventing the production of cytokines involved in inflammatory processes. They have the potential to provide immunomodulatory benefits across a broad range of diseases. This narrative review focuses on the safety profile of tofacitinib, baricitinib, upadacitinib, and...
Source: International Journal of Rheumatic Diseases - June 15, 2021 Category: Rheumatology Authors: Peter Nash, Irwin Lim, Mona Marabani Tags: INVITED REVIEW Source Type: research

Issue Information
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 15, 2021 Category: Rheumatology Tags: ISSUE INFORMATION Source Type: research

Efficacy of aqua ‐based plyometric exercises in the rehabilitation of patients with juvenile dermatomyositis: A randomized crossover pilot study
AbstractBackgroundPatients with juvenile dermatomyositis (JDM) experience muscle weakness, tiredness, and loss of energy, which restrict their abilities in performance of their daily living activities.ObjectiveTo explore the effect of aquatic-based plyometric (Aqua-PLYO) exercises on muscle strength, fatigue, and functional ability in patients with JDM.MethodsThis was a randomized, single-blind, crossover pilot study that included 16 patients with JDM (age 13.44  ± 2.85 years). They were assigned randomly to receive either the Aqua-PLYO exercises (n = 8) or the standard outpatient care (SoC ...
Source: International Journal of Rheumatic Diseases - June 14, 2021 Category: Rheumatology Authors: Ragab K. Elnaggar, Walaa A. Abd El ‐Nabie Tags: ORIGINAL ARTICLE Source Type: research

Greater trochanteric pain syndrome in women: Analysis of magnetic resonance, sagittal alignment, muscular strength and endurance of the hip and trunk
AbstractIntroductionThere are many studies on the Greater Trochanteric Pain Syndrome (GTPS), however its relationship with radiographic and biomechanics parameters is not established.ObjectiveTo compare the magnetic resonance images (MRI) of the hip, radiographic parameters of sagittal alignment (pelvic incidence, sacral slope and lumbar lordosis), muscular strength and endurance in women with and without GTPS.MethodsForty women, age over 45, IMC  .05), sacral slope (P >  .05) and lumbar lordosis (P >  .05). The GTPSG showed lower strength of all hip muscle groups (abductors, adductors, flexo...
Source: International Journal of Rheumatic Diseases - June 10, 2021 Category: Rheumatology Authors: Maur ício Rodrigues Miyasaki, Marieli Araujo Rossoni Marcioli, Amanda Paula Ricardo Rodrigues da Cunha, Giancarlo Cavalli Polesello, Marcelo Garcia Marini, Karen Barros Parron Fernandes, Christiane de Souza Guerino Macedo Tags: ORIGINAL ARTICLE Source Type: research

Your help is needed in the fight against COVID ‐19: Please contribute to the COVID‐19 Global rheumatology alliance registry
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 8, 2021 Category: Rheumatology Tags: APLAR MATTERS Source Type: research

Issue Information
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 7, 2021 Category: Rheumatology Tags: ISSUE INFORMATION Source Type: research

Is Tai Chi beneficial for rheumatoid arthritis? —A Cochrane Review summary with commentary
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 7, 2021 Category: Rheumatology Authors: Francesco Negrini Tags: COCHRANE CORNER Source Type: research

Survivin promotes rheumatoid arthritis fibroblast ‐like synoviocyte cell proliferation, and the expression of angiogenesis‐related proteins by activating the NOTCH pathway
ConclusionThis study confirmed that survivin promotes RA-HFLS cell proliferation, the expression of angiogenesis-related proteins and suppresses apoptosis by activating the NOTCH pathway. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 7, 2021 Category: Rheumatology Authors: Sha Ma, Jing Wang, Jun Lin, Song Jin, Fang He, Jian Mei, Hong Zhang, Shuya Wang, Qin Li Tags: ORIGINAL ARTICLE Source Type: research

Prevalence of metabolic syndrome in patients with rheumatoid arthritis in eastern China —A hospital based study
AbstractObjectiveThe purpose of this hospital clinic based study was to evaluate the potential risk factors associated with the prevalence of MetS in RA population.MethodsFrom January 2015 to October 2018, 717 patients with RA and 717 healthy controls who were treated or performed physical examination in Tianjin First Central Hospital were enrolled in this study. The basic disease diagnoses were recorded. A questionnaire was performed on all participants to assess the demographic details of the RA cohort. Moreover, laboratory indicators related to glucose and lipid metabolism in patients with RA were also detected. The pot...
Source: International Journal of Rheumatic Diseases - June 4, 2021 Category: Rheumatology Authors: Chun ‐yu Kong, Chang‐lei Wang, Kai‐jun Niu, Wufang Qi Tags: ORIGINAL ARTICLE Source Type: research

Systematic review and meta ‐analysis on prevalence of metabolic syndrome in psoriatic arthritis, rheumatoid arthritis and psoriasis
ConclusionThe prevalence of MetS is significantly increased in PsA populations compared with PsO and RA populations. Further studies should be performed using a standardized definition of MetS in PsA, RA, and PsO populations to determine whether addressing the metabolic components in MetS offers any therapeutic benefits and in terms of attaining MDA and improving cardiovascular health. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 2, 2021 Category: Rheumatology Authors: Aravinthan Loganathan, Narainraj Kamalaraj, Carlos El ‐Haddad, Kevin Pile Tags: ORIGINAL ARTICLE Source Type: research

A multicenter longitudinal study of the prevalence and mortality rate of systemic lupus erythematosus patients in Oman: Oman Lupus Study
ConclusionThis study showed that the mean prevalence of SLE in Oman to be 38.8 (range 5-63) per 100  000 inhabitants. The 40-year survival rate among patients with positive ANA was found to be 90%, while patients with negative ANA had worse survival outcomes. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - June 1, 2021 Category: Rheumatology Authors: Nasra K. Al ‐Adhoubi, Farida Al‐Balushi, Issa Al Salmi, Maha Ali, Talal Al Lawati, Batool S. H. Al Lawati, Reem Abdwani, Ali Al Shamsi, Juma Al Kaabi, Musallam Al Mashaani, Divij Krishna Jha, Sherin Sayed, Tariq Al‐Araimi, Prabha Liyana Tags: ORIGINAL ARTICLE Source Type: research