Short ‐term pain trajectories in patients with knee osteoarthritis
AbstractAimIt is unknown if pain in knee osteoarthritis (KOA) follows distinct patterns over the short term. Therefore, the aim of this study was to identify whether persons with a previous history of KOA pain fluctuations have distinct trajectories of pain over 90  days and to examine associations between baseline characteristics and pain trajectories.MethodPeople with a previous history of KOA were selected from a web-based longitudinal study. Baseline variables were sex, age, being obese/overweight, years of KOA, knee injury, knee buckling, satisfactory Lubben Social Support Score, pain and stress scales, Intermitt...
Source: International Journal of Rheumatic Diseases - January 26, 2022 Category: Rheumatology Authors: Inoshi Atukorala, Aron Downie, Arunasalam Pathmeswaran, Leticia Miranda Alle Deveza, Thashi Chang, Yuqing Zhang, David John Hunter Tags: ORIGINAL ARTICLE Source Type: research

Is image ‐guided glucocorticoid injection better than blind injection for shoulder pain? A Cochrane Review summary with commentary
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 26, 2022 Category: Rheumatology Authors: Giovanni Iolascon, Marco Paoletta Tags: COCHRANE CORNER Source Type: research

The value of SPARCC sacroiliac MRI scoring in axial psoriatic arthritis and its association with other disease parameters
ConclusionAlthough radiologic involvement is generally not severe in AxPsA, MRI still provides additional information about inflammatory activity and structural lesions. CRP may be helpful in monitoring the radiologic disease activity in AxPsA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 26, 2022 Category: Rheumatology Authors: Halise Hande Gezer, Mehmet Tuncay Duru öz Tags: ORIGINAL ARTICLE Source Type: research

The diagnostic accuracy of temporal artery ultrasound and temporal artery biopsy in giant cell arteritis: A single center Australian experience over 10  years
ConclusionTemporal artery ultrasound is a useful non-invasive investigation in the assessment of suspected GCA. If positive in the setting of a suggestive clinical presentation, a temporal artery ultrasound probably avoids the need for a temporal artery biopsy. Temporal artery ultrasound could be more widely used in the clinical management of GCA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 23, 2022 Category: Rheumatology Authors: Jianna He, Luke Williamson, Beverly Ng, Jeremy Wang, Nicholas Manolios, Socrates Angelides, David Farlow, Peter K. K. Wong Tags: ORIGINAL ARTICLE Source Type: research

Multisystem inflammatory syndrome in children associated with erythema multiforme ‐like eruption following COVID‐19
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 22, 2022 Category: Rheumatology Authors: Nesrine Ben Salah, Ines Lahouel, Chbil Ben Mariem, Khawla Trimech, Ahlem Bellallah, Sleh Chouchene, Jameleddine Zili Tags: CORRESPONDENCE Source Type: research

Pyoderma gangrenosum of the breast associated with rheumatoid arthritis: A challenging diagnosis
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 22, 2022 Category: Rheumatology Authors: Nour El Imene Ouni, Mouna Korbi, Nesrine Ben Salah, Mariem Kammoun, Bellalah Ahlem, Hichem Belhadjali, Monia Youssef, Abdelfattah Zakhama, Mongi Touzi, Jameleddine Zili Tags: CORRESPONDENCE Source Type: research

Efficacy of adding pain neuroscience education to a  multimodal treatment in fibromyalgia: A systematic review and meta‐analysis
AbstractThe aim of this study was to investigate whether adding pain neuroscience education (PNE) to a multimodal approach has additional benefits in patients with fibromyalgia (FM). The methodology of this study was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The methods and strategies applied in the study were registered in PROSPERO (CRD42021272246). A systematic search with related search terms in the PubMed, Ebsco (Academic Search Ultimate), Cochrane Library, Physiotherapy Evidence Database (PEDro), Medline (Ebsco), Cinahl (Ebsco), Scopus and Web of Sc...
Source: International Journal of Rheumatic Diseases - January 21, 2022 Category: Rheumatology Authors: Ismail Saracoglu, Esra Akin, G ökce Basak Aydin Dincer Tags: REVIEW Source Type: research

Disseminated drug ‐resistant tuberculosis and multiple autoimmune syndrome in a child with selective IgA deficiency—An uncustomary combination
AbstractPolyautoimmunity or multiple autoimmune syndrome (MAIS) is increasingly being recognized in pediatric clinical practice, often in conjunction with systemic lupus erythematosus (SLE). Besides multi-organ autoimmunity, children with SLE are often at a higher risk of developing infections including tuberculosis. The tendency to develop infections and multiple autoimmune diseases in childhood SLE often occurs in the absence of monogenic primary immunodeficiency disease. Conversely, children with inborn errors of immunity, of which selective IgA deficiency (sIgAD) is the most common, may develop recurrent infections and...
Source: International Journal of Rheumatic Diseases - January 20, 2022 Category: Rheumatology Authors: Harshita Nori, Viresh Vohra, Aaqib Zaffar Banday, Ankur Kumar Jindal, Reva Tyagi, Mandeep Kaur Sodhi, Amanjit Bal, Deepti Suri Tags: APLAR GRAND ROUND CASE Source Type: research

Differences of clinicopathological features between IgG4 ‐related and non‐IgG4‐related idiopathic retroperitoneal fibrosis
ConclusionsIdiopathic retroperitoneal fibrosis can be classified into IgG4-related and non-IgG4-related subtypes. There were no significant pathological differences between the two subtypes of IRF, except for the IgG4 staining. Patients with the IgG4 subtype tended to be more likely to be male, have a higher inflammatory index, and be more likely to have recurrence. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 19, 2022 Category: Rheumatology Authors: Juan Li, Huanan Wang, Min Wang, Fenghuang Xu, Feng Guo, Feng Ye Tags: ORIGINAL ARTICLE Source Type: research

The prevalence and correlates of depression in Korean adults with rheumatoid arthritis: Results from the Korea National Health and Nutrition Examination Surveys
ConclusionDepression is significantly prevalent in Korean RA patients. Along with managing pain and daily life functions, interventions to reduce perceived stress are needed for comprehensive RA management. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 19, 2022 Category: Rheumatology Authors: Hyunseuk Kim, Haeyoung Lee, Sang ‐Shin Lee Tags: ORIGINAL ARTICLE Source Type: research

APLAR recommendations on the practice of telemedicine in rheumatology
ConclusionThese recommendations provide guidance for the approach and use of telemedicine in rheumatology care to guide highest possible standards of clinical care and to enable equitable patient reach. However, since evidence in telemedicine care in rheumatology is limited and emerging, most recommendations will need further consideration when more data are available. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 19, 2022 Category: Rheumatology Authors: Sakir Ahmed, Rebecca Grainger, Anindita Santosa, Asal Adnan, Khalid A. Alnaqbi, Yi ‐Hsing Chen, Chengappa Kavadichanda, Nang San Kyauk Kaw, Amy Kelly, Saira Elaine Anwer Khan, Basel Masri, Shweta Nakarmi, Faisal Parlindungan, Nazibur Rahman Tags: REVIEW Source Type: research

Eosinophilic fasciitis induced by a game of drumming probably via type 2 innate immunity
We report a case of eosinophilic fasciitis triggered by strenuous physical activity, which did not relapse during the follow-up period. We ascertained that interleukin-33 (IL-33) was released from the vascular endothelial cells after intense exercise, inducing type 2 innate lymphocytes (ILC2) and causing fasciitis. A healthy woman experienced itching on both limbs a few hours after a game of drumming. Her hand, knee joints, and legs gradually swelled up with groove signs along the superficial veins. White blood cell and eosinophil counts were significantly elevated. Magnetic resonance imaging revealed a high signal at the ...
Source: International Journal of Rheumatic Diseases - January 13, 2022 Category: Rheumatology Authors: Seimi Watanabe, Makoto Kondo, Masako Ichishi, Akinobu Hayashi, Yoshiaki Matsushima, Yoshifumi Hirokawa, Koji Habe, Keiichi Yamanaka Tags: NOVEL HYPOTHESIS Source Type: research

Association between Klebsiella pneumoniae and ankylosing spondylitis: A systematic review and meta ‐analysis
ConclusionWhen compared with healthy people, a significantly higher positive rate ofK. pneumoniae in feces, serum IgA and IgG were observed in patients with AS, suggesting thatK. pneumoniae probably plays a crucial role in the occurrence of AS. The findings in this study need further prospective investigations for confirmation. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 12, 2022 Category: Rheumatology Authors: Fayu Long, Taiping Wang, Qing Li, Yiquan Xiong, Yong Zeng Tags: ORIGINAL ARTICLE Source Type: research

Both ASDAS and ADC are associated with spinal mobility in active axial spondyloarthritis: A comparison between early and later disease
AbstractObjectiveUsing diffusion-weighted imaging (DWI)-derived apparent diffusion coefficient (ADC), we aimed to determine the relationship between intensity of spinal inflammation and mobility in patients with axial spondyloarthritis (SpA) in early and later stages of active disease. The Ankylosing Spondylitis Disease Activity Score (ASDAS) was also used for a more comprehensive evaluation.MethodsParticipants with axial SpA and back pain were recruited from 10 rheumatology centers. Clinical, biochemical and radiological parameters were collected. Short tau inversion recovery (STIR) sequence magnetic resonance imaging (MR...
Source: International Journal of Rheumatic Diseases - January 12, 2022 Category: Rheumatology Authors: Ho Yin Chung, Shirley Chiu Wai Chan, Kam Ho Lee, Helen Hoi Lun Tsang, Ling Ling Ng, Chak Sing Lau Tags: ORIGINAL ARTICLE Source Type: research

Association of tumor necrosis factor ‐α inhibitors and liver cirrhosis in patients with rheumatoid arthritis: A nationwide population‐based nested case‐control study
ConclusionWe found no association between the use of TNF- α inhibitors and development of liver cirrhosis in RA patients. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 8, 2022 Category: Rheumatology Authors: Der ‐Yuan Chen, Ching‐Heng Lin, Hsin‐Hua Chen, Kuo‐Tung Tang Tags: ORIGINAL ARTICLE Source Type: research

B7 immune checkpoint family members as putative therapeutics in autoimmune disease: An updated overview
AbstractAutoimmune diseases, especially among young people in the US, are one of the leading causes of morbidity and death. The immune responses are the fundamental pathogenicity of autoimmune disorders. The equilibrium between stimulatory and inhibitory signals is critical for the stimulation, migration, survival, and T cell-related immune responses. The B7 family can substantially regulate T cell-mediated immune responses. Nevertheless, recent breakthroughs in immune checkpoint blockade in cancer immunotherapy have facilitated autoimmune diseases, especially among the prone populations. In the current study, we tried to ...
Source: International Journal of Rheumatic Diseases - January 7, 2022 Category: Rheumatology Authors: Katayoun Dolatkhah, Nazila Alizadeh, Hanieh Mohajjel ‐Shoja, Mahdi Abdoli Shadbad, Khalil Hajiasgharzadeh, Leili Aghebati‐Maleki, Amir Baghbanzadeh, Negar Hosseinkhani, Noora Karim Ahangar, Behzad Baradaran Tags: REVIEW Source Type: research

Predictive factors for retention of golimumab over a median 4 ‐year duration in Japanese patients with rheumatoid arthritis in a real‐world setting: A retrospective study and literature review
ConclusionsPrior exposure of increasing number of biologics was identified as the most important factor negatively affecting long-term golimumab retention in Japanese patients with RA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 6, 2022 Category: Rheumatology Authors: Tomoyuki Mutoh, Taichi Nagai, Tsuyoshi Shirai, Soshi Okazaki, Hiroko Sato, Hiroshi Fujii Tags: ORIGINAL ARTICLE Source Type: research

Transition readiness assessment in adolescents and young adults with rheumatic diseases: The Singapore experience
AbstractBackgroundTransition from pediatric to adult care is a challenging time for adolescents and young adults (AYA) with rheumatic diseases. Validated tools have been developed to assess transition readiness.AimTo evaluate transition readiness among AYA with rheumatic diseases and to identify factors associated with transition readiness.MethodsPatients ≥15 years old were enrolled into our transition program and administered a Transition Readiness Assessment Tool (TRAT) from July 2017. The TRAT consists of 3 components: (a) patient's perception on importance of transition and confidence toward transition on a Lik...
Source: International Journal of Rheumatic Diseases - January 6, 2022 Category: Rheumatology Authors: Kai Liang Teh, Sook Fun Hoh, Su ‐Wan Bianca Chan, Xiaocong Gao, Lena Das, Yun Xin Book, Thaschawee Arkachaisri Tags: ORIGINAL ARTICLE Source Type: research

Enhanced arthrocentesis of the effusive knee with pneumatic compression
AbstractAimComplete arthrocentesis of the effusive knee ameliorates patient pain, reduces intra-articular and intraosseous pressure, removes inflammatory cytokines, and has been shown to substantially improve the therapeutic outcomes of intra-articular injections. However, conventional arthrocentesis incompletely decompresses the knee, leaving considerable residual synovial fluid in the intra-articular space. The present study determined whether external pneumatic circumferential compression of the effusive knee permitted more successful arthrocentesis and complete joint decompression.MethodsUsing a paired sample design, 5...
Source: International Journal of Rheumatic Diseases - January 5, 2022 Category: Rheumatology Authors: Sumir Brahmbhatt, Ahsan Iqbal, Fatemeh Jafari Farshami, Maheswari Muruganandam, Jaren R. Trost, David R. Cisneros, Adnan N. Kiani, Matthew K. McElwee, William A. Hayward, Luke J. Haseler, Philip A. Band, Wilmer L. Sibbitt Tags: ORIGINAL ARTICLE Source Type: research

Altered bacterial profiles at genus level in the gut of ankylosing spondylitis patients with different ASDAS scores
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 4, 2022 Category: Rheumatology Authors: Yuquan You, Meimei Cai, Wei Zhang, Jun Sheng Lin Tags: CORRESPONDENCE Source Type: research

Early experience of COVID ‐19 vaccine‐related adverse events among adolescents and young adults with rheumatic diseases: A single‐center study
AbstractObjectiveConsidering the concerns regarding the coronavirus disease-2019 (COVID-19) vaccine safety among pediatric patients with inflammatory rheumatic diseases (IRD) due to a lack of data, an urgent need for studies evaluating safety profiles of vaccines emerged.MethodsAmong participants vaccinated by CoronaVac inactive SARS-CoV-2 or BNT162b2 messenger RNA (mRNA) COVID-19 (Pfizer-BioNTech) vaccine, healthy children under 18 and patients under 21 with an at least 1-year follow-up period in our department for a childhood-onset rheumatic disease were included into this cross-sectional study.ResultsOverall, 246 subjec...
Source: International Journal of Rheumatic Diseases - January 4, 2022 Category: Rheumatology Authors: Fatih Haslak, Aybuke Gunalp, Memnune Nur Cebi, Mehmet Yildiz, Amra Adrovic, Sezgin Sahin, Kenan Barut, Ozgur Kasapcopur Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 3, 2022 Category: Rheumatology Tags: ISSUE INFORMATION Source Type: research

COVID ‐19 vaccination can occasionally trigger autoimmune phenomena, probably via inducing age‐associated B cells
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - January 3, 2022 Category: Rheumatology Authors: Naim Mahroum, Yehuda Shoenfeld Tags: EDITORIAL Source Type: research

Interleukin ‐22 and the diagnosis of axial spondyloarthritis
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 31, 2021 Category: Rheumatology Authors: Maroua Slouma, Lobna Kharrat, Imen Gharsallah Tags: CORRESPONDENCE Source Type: research

Response to a letter by M. Slouma et al
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 31, 2021 Category: Rheumatology Authors: Michal Sagiv, Mohammad Adawi, Abid Awisat, Aniela Shouval, Regina Peri, Firas Sabbah, Itzhak Rosner, Aharon Kessel, Gleb Slobodin Tags: CORRESPONDENCE Source Type: research

The economic burden of systemic sclerosis —A systematic review
ConclusionsLarge variations existed in annual costs of SSc, but all studies found that SSc imposed a substantial economic burden on patients and their families. The identified studies were mostly from high-income countries and there is still a knowledge gap regarding the cost of SSc in other parts of the world. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 31, 2021 Category: Rheumatology Authors: Yongcong Chen, Lin Wu, Jose J. Hern ández‐Muñoz, Michael J. Miller, Melinda Pope, Yidan Huyan, Lixian Zhong Tags: ORIGINAL ARTICLE Source Type: research

Correspondence reply to authors J A Vondenberg et: RE: Increased malignancies in systemic sclerosis (IJRD: IJRD ‐2021‐0787)
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 27, 2021 Category: Rheumatology Authors: Monique S. Rees, Chris Frampton, Douglas H. N. White, Kamal K. Solanki Tags: CORRESPONDENCE Source Type: research

Performance of the 2019 European League Against Rheumatism/American College of Rheumatology classification criteria for systemic lupus erythematosus in a multiethnic Malaysian cohort
ConclusionThe EULAR/ACR performed well in our cohort. The EULAR/ACR and SLICC 2012 showed higher sensitivity than the ACR 1997, and the EULAR/ACR showed similar specificity to the ACR 1997 and SLICC 2012 overall, in early disease, and across the different ethnicities. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 24, 2021 Category: Rheumatology Authors: Shakira Selvananda, Sow Lai Kan Tags: ORIGINAL ARTICLE Source Type: research

Early control of C ‐reactive protein levels with non‐biologics is associated with slow radiographic progression in radiographic axial spondyloarthritis
This study aimed to investigate the relationship between changes in the CRP level and spinal radiographic progression in patients with radiographic axial spondyloarthritis who were initially treated with non-biologics.MethodsPatients with radiographic axial spondyloarthritis who were followed up for 18  years at a single center and initially treated with nonsteroidal anti-inflammatory drugs and/or conventional disease-modifying antirheumatic drugs for 3 months were included. Patients with a CRP level of
Source: International Journal of Rheumatic Diseases - December 22, 2021 Category: Rheumatology Authors: Bon San Koo, Seunghun Lee, Ji Seon Oh, Seo Young Park, Ga Young Ahn, Ji Hui Shin, Kyung Bin Joo, Tae ‐Hwan Kim Tags: ORIGINAL ARTICLE Source Type: research

2021 Asia ‐Pacific League of Associations for Rheumatology clinical practice guideline for treatment of gout
ConclusionRecommendations for clinically relevant scenarios in the management of gout were formulated to guide physicians in administering individualized care. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 21, 2021 Category: Rheumatology Authors: Jose Paulo P. Lorenzo, Ma. Hanna Monica Z. Sollano, Evelyn O. Salido, Julie Li ‐Yu, Sandra A. Tankeh‐Torres, Ida Ayu Ratih Wulansari Manuaba, Md Mujibur Rahman, Binoy J. Paul, Mo Yin Mok, Monika De Silva, Prasanta Padhan, Ai Lee Lim, Melvi Tags: ORIGINAL ARTICLE Source Type: research

(Un)disclosed. Disease disclosure in people living with rheumatic diseases: An exploratory study
AbstractObjectiveLittle is known about disease-related disclosure (DD) in patients with rheumatic musculoskeletal diseases (RMDs). We aim to investigate DD behaviors and to explore which socio-demographic, clinical and psychological factors play a role in this self-disclosure process among patients with RMDs.MethodsA cross-sectional Italian nationwide study captured DD in RMDs in different contexts (workplace, family, friends, partner, social networks). An ad hoc survey was developed and disseminated by the Patients' Association ALOMAR ODV (Lombard Association for Rheumatic Diseases) between June and July 2020. Patient dem...
Source: International Journal of Rheumatic Diseases - December 21, 2021 Category: Rheumatology Authors: Silvia Maria Teresa Ostuzzi, Francesca Ingegnoli, Caterina Pistarini, Edoardo Nicol ò Aiello, Elena Maria Fiabane Tags: ORIGINAL ARTICLE Source Type: research

Increased gene expression of B cell ‐activating factor of tumor necrosis factor family, in remitting antineutrophil cytoplasmic antibody‐associated vasculitis patients
AbstractAimTo study the expression of B cell-activating factor of tumor necrosis factor family (BAFF) and A proliferation-inducing ligand (APRIL) genes in active and remitting patients with anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) and healthy controls and their correlation with disease activity.MethodsThis was a prospective case-control study. Gene expressions of BAFF and APRIL were studied in 32 patients with AAV (16 each with active disease and in remission) and 30 healthy age and sex matched controls by real-time polymerase chain reaction.ResultsOut of 32 AAV patients, 26 had granulomatosis with ...
Source: International Journal of Rheumatic Diseases - December 16, 2021 Category: Rheumatology Authors: Saket Jha, Jagdeep Singh, Ranjana W. Minz, Aadhar Dhooria, GSRSNK Naidu, Rajiv Ranjan Kumar, Manish Rathi, Sanjay Jain, Shashi Anand, Aman Sharma Tags: ORIGINAL ARTICLE Source Type: research

Diagnostic codes for low back pain, nomenclature or noise? A  descriptive study of disease classification system coding of low back pain
ConclusionLBP diagnostic codes used in popular disease classification systems are out of touch with current approaches to diagnosis, as reflected in contemporary LBP guidelines. Our findings suggest these disease classification systems need revision, but precisely how they should be revised is unclear. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 15, 2021 Category: Rheumatology Authors: Mamata Tamrakar, Mary O ’Keeffe, Adrian C. Traeger, Ian Harris, Christopher Maher Tags: ORIGINAL ARTICLE Source Type: research

Outcome of low ‐dose prednisolone use for the induction of remission in lupus nephritis patients
ConclusionsIt has been observed that low-dose prednisolone regimen may be effective in LN. Steroid dose-related side effects and rate of infections were lower in this group. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 13, 2021 Category: Rheumatology Authors: Iftekhar Hussain Bandhan, Md. Nazrul Islam, Habib Imtiaz Ahmad, Abul Khair Ahmedullah Tags: ORIGINAL ARTICLE Source Type: research

Clinical features and prognostic factors of systemic sclerosis in Guangxi, China: Retrospective, single ‐center study of long‐term survival in 470 patients
AbstractObjectiveSystemic sclerosis (SSc) is an autoimmune disease the prevalence of which varies among populations. We analyzed SSc patients from Guangxi to improve the clinical understanding of this disease.MethodsData of 470 SSc patients admitted to our institution from October 2021 to January 2019 were examined. The characteristics of these patients were analyzed using Kaplan-Meier survival analysis. Cox proportional-hazard regression was used to identify prognostic factors.ResultsThe average age was 50.44  ± 12.31 years, 285 patients (60.6%) were women, 2.1% had pneumoconiosis, 58.2% had pulmonar...
Source: International Journal of Rheumatic Diseases - December 10, 2021 Category: Rheumatology Authors: Juan Chen, Chenxi Yang, Jie Pan, Cheng Zhao, Zhanrui Chen, Jing Wen, Fei Dong, Xiaoling Liao, Ling Lei Tags: ORIGINAL ARTICLE Source Type: research

Janus kinase inhibition in induction treatment of anti ‐MDA5 juvenile dermatomyositis‐associated rapidly progressive interstitial lung disease
AbstractTofacitinib has an important role in pediatric rapidly progressive interstitial lung disease (ILD) associated with juvenile dermatomyositis (JDM), an otherwise potentially fatal condition. It may be useful in induction of remission and can be used safely to maintain remission. Serum ferritin and interleukin-18 are useful markers for tracking activity and response of JDM-associated ILD. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 9, 2021 Category: Rheumatology Authors: Poh Lin Pauline Chan Ng, Archana Mopur, Daniel Yam Thiam Goh, Mahesh  Babu Ramamurthy, Michael Teik Chung Lim, Lee Kean Lim, Pei Ling Ooi, Elizabeth Youning Ang Tags: APLAR GRAND ROUND CASE Source Type: research

Metabolic obesity and the risk of knee osteoarthritis progression in elderly community residents: A 3 ‐year longitudinal cohort study
ConclusionIn this cohort, metabolic effects of obesity on knee cartilage damage and BML were not demonstrated. Further large-scale studies are required to prove the causal relationship between metabolic obesity and knee OA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 8, 2021 Category: Rheumatology Authors: Dong Jin Go, Dong Hyun Kim, Ali Guermazi, Michel Daoud Crema, David J. Hunter, Hyun Sook Hwang, Hyun Ah Kim Tags: ORIGINAL ARTICLE Source Type: research

Successful treatment of children with juvenile systemic sclerosis using mycophenolate mofetil after methylprednisolone pulse therapy: A 3 ‐year follow‐up
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 8, 2021 Category: Rheumatology Authors: Akinori Furusawa, Hiroyuki Wakiguchi, Fumiko Okazaki, Yuno Korenaga, Yoshihiro Azuma, Hiroki Yasudo, Shunji Hasegawa Tags: CORRESPONDENCE Source Type: research

Gene polymorphisms of SIRT1 in patients with rheumatoid arthritis
ConclusionThe findings suggest that rs3740051, rs7069102 and rs1467568 variants in SIRT1 gene are related to RA susceptibility in a Chinese Han population. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 6, 2021 Category: Rheumatology Authors: Jie Zhou, Yan ‐Wei He, Lu Fu, You‐Yu Lan, Xiao‐Yan Liu, Qian Wu, Wang‐Dong Xu, An‐Fang Huang Tags: ORIGINAL ARTICLE Source Type: research

Ultrasonography of auricular cartilage is a potential tool for diagnosing relapsing polychondritis and monitoring disease activity
ConclusionAssessment of RP lesions by ultrasonography is useful for the evaluation of cartilaginous lesions and monitoring of disease activity, especially when considering the treatment response and the timing of drug tapering. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 5, 2021 Category: Rheumatology Authors: Mitsuharu Yoshida, Yoshinori Taniguchi, Takeshi Yoshida, Hirofumi Nishikawa, Yoshio Terada Tags: ORIGINAL ARTICLE Source Type: research

Screening rates and prevalence of osteoporosis in a real ‐world, Australian systemic sclerosis cohort
We report rates of dual-energy X-ray absorptiometry (DXA) scanning in an SSc cohort at a tertiary hospital specialized outpatient clinic and the prevalence and associations of osteoporosis in screened patients.MethodWe performed retrospective chart review to determine if patients underwent DXA scanning between 2007 and 2018 and extracted lumbar spine and femoral neck T-scores, fracture history, and osteoporosis therapy.ResultsOf 244 patients, 104 (42.6%) underwent DXA scanning and among patients in whom T-scores were available (n = 91), 30 (33.0%) had osteoporosis and 48 (52.7%) had osteopenia. Screened patients were more ...
Source: International Journal of Rheumatic Diseases - December 3, 2021 Category: Rheumatology Authors: Gayathri Bimal, Joanne Sahhar, Monika Savanur, Gene ‐Siew Ngian Tags: ORIGINAL ARTICLE Source Type: research

Recent advances in Pediatric Rheumatology: July to September 2021
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 3, 2021 Category: Rheumatology Authors: Pallavi L. Nadig, Reva Tyagi, Surjit Singh Tags: EXPERT COMMENTS Source Type: research

Issue Information
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 2, 2021 Category: Rheumatology Tags: ISSUE INFORMATION Source Type: research

Is a fat thumb another sign of psoriatic arthritis?
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 2, 2021 Category: Rheumatology Authors: Kevin Pile Tags: EDITORIAL Source Type: research

Your help is needed in the fight against COVID ‐19: Please contribute to the COVID‐19 Global rheumatology alliance registry
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 2, 2021 Category: Rheumatology Tags: APLAR MATTERS Source Type: research

What are the effects of vasodilators in patients with primary Raynaud ’s phenomenon? A Cochrane review summary with commentary
(Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - December 1, 2021 Category: Rheumatology Authors: Ilke Coskun Benlidayi Tags: COCHRANE CORNER Source Type: research

Baseline characteristics of systemic sclerosis patients with restrictive lung disease in a multi ‐center US‐based longitudinal registry
AbstractAimInterstitial lung disease (ILD) is the leading cause of disease-related death in systemic sclerosis (SSc). Here, we assess baseline characteristics of SSc subjects with and without restrictive lung disease (RLD) in a multi-center, US-based registry.MethodsSSc patients within 5  years of disease onset were enrolled in the Collaborative National Quality and Efficacy Registry (CONQUER), a multi-center US-based registry of SSc study participants (age ≥ 18 years) enrolled at 13 expert centers. All subjects met 2013 American College of Rheumatology / European League Again st Rheumatism criteria....
Source: International Journal of Rheumatic Diseases - November 30, 2021 Category: Rheumatology Authors: Flavia V. Castelino, John M. VanBuren, Emily Startup, Shervin Assassi, Elana J. Bernstein, Lorinda Chung, Chase Correia, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Faye N. Hant, Laura K. Hummers, Dinesh Khanna, Nora Sandorfi, Ami A. S Tags: ORIGINAL ARTICLE Source Type: research

Increased serum AXL is associated with radiographic knee osteoarthritis severity
AbstractObjectiveTo investigate the expression and clinical significance of serum soluble AXL in patients with radiographic knee osteoarthritis (KOA).MethodsThere were 183 patients with KOA who were selected and divided based on the Kellgren-Lawrence (KL) score into KL 0 subgroups (n  = 42), KL I-II subgroups (n = 90), and KL III-IV subgroups (n = 51). Healthy volunteers (n = 170) in our hospital were selected with matched age and gender as the control group. AXL level in serum was detected by enzyme-linked immunosorbent assay. The correlation between serum AXL with seve rity and cli...
Source: International Journal of Rheumatic Diseases - November 29, 2021 Category: Rheumatology Authors: Shao Zhenghai Tags: ORIGINAL ARTICLE Source Type: research

Characteristics of monosodium urate crystal deposition in the foot in the different stages of gout by dual ‐energy computed tomography
This study included 101 patients with gout, 64 had early gout (3  years). We retrospectively compared the total volumes of MSU crystals, the detection rates, and the morphology of MSU crystals at specific anatomical sites in the foot of the patients with different gout durations.ResultsThe total volume of MSU crystals in patients with early gout was significantly smaller than that in patients with late gout (P 
Source: International Journal of Rheumatic Diseases - November 26, 2021 Category: Rheumatology Authors: Yan Zhang, Aihui Di, Huishu Yuan Tags: ORIGINAL ARTICLE Source Type: research

Associations between radiographic features, clinical features and ultrasound of thumb ‐base osteoarthritis: A secondary analysis of the COMBO study
ConclusionThis study indicates that radiographic features significantly correlate with hand function, and ultrasound PDS is closely related to the PGA at baseline in thumb-base OA. Radiographic JSN may be a predictor for stiffness and PGA in thumb-base OA. (Source: International Journal of Rheumatic Diseases)
Source: International Journal of Rheumatic Diseases - November 25, 2021 Category: Rheumatology Authors: Ying Shi, Kai Fu, Win Min Oo, Leticia A. Deveza, Xia Wang, Vicky Duong, Sarah R. Robbins, David J. Hunter Tags: ORIGINAL ARTICLE Source Type: research